메뉴 건너뛰기




Volumn 7, Issue 3, 2008, Pages 704-711

Overexpression of PTEN in ovarian cancer cells suppresses i.p. dissemination and extends survival in mice

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; VASCULOTROPIN;

EID: 41649111488     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0724     Document Type: Article
Times cited : (34)

References (41)
  • 2
    • 41649121976 scopus 로고    scopus 로고
    • Changes in mortality rate of major malignant tumors by organ
    • 1997: vital statistics. Tokyo: Ministry of Health and Welfare;
    • Japan MoHaWo. Changes in mortality rate of major malignant tumors by organ. In: Annual report on health and welfare, 1997: vital statistics. Tokyo: Ministry of Health and Welfare; 1997.
    • (1997) Annual report on health and welfare
    • MoHaWo, J.1
  • 3
    • 0030054309 scopus 로고    scopus 로고
    • Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer
    • McGuire WP, Hoskins WJ, Brady MF, et al. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer. N Engl J Med 1996;334:1-6.
    • (1996) N Engl J Med , vol.334 , pp. 1-6
    • McGuire, W.P.1    Hoskins, W.J.2    Brady, M.F.3
  • 4
    • 1542577513 scopus 로고    scopus 로고
    • A feasibility study of paclitaxel and carboplatin therapy in Japanese patients with epithelial ovarian cancer
    • Takei Y, Suzuki M, Ohwada M, et al. A feasibility study of paclitaxel and carboplatin therapy in Japanese patients with epithelial ovarian cancer. Oncol Rep 2003;10:951-5.
    • (2003) Oncol Rep , vol.10 , pp. 951-955
    • Takei, Y.1    Suzuki, M.2    Ohwada, M.3
  • 5
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • Steck PA, Pershouse MA, Jasser SA, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997;15:356-62.
    • (1997) Nat Genet , vol.15 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3
  • 6
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-7.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 7
    • 0033556443 scopus 로고    scopus 로고
    • Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: Differential involvement of focal adhesion kinase and p130Cas
    • Tamura M, Gu J, Takino T, Yamada KM. Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. Cancer Res 1999;59:442-9.
    • (1999) Cancer Res , vol.59 , pp. 442-449
    • Tamura, M.1    Gu, J.2    Takino, T.3    Yamada, K.M.4
  • 8
    • 0030799909 scopus 로고    scopus 로고
    • Somatic mutations of PTEN in glioblastoma multiforme
    • Wang SI, Puc J, Li J, et al. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 1997;57:4183-6.
    • (1997) Cancer Res , vol.57 , pp. 4183-4186
    • Wang, S.I.1    Puc, J.2    Li, J.3
  • 9
    • 0030777104 scopus 로고    scopus 로고
    • Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
    • Guldberg P, thor Straten P, Birck A, Ahrenkiel V, Kirkin AF, Zeuthen J. Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res 1997;57:3660-3.
    • (1997) Cancer Res , vol.57 , pp. 3660-3663
    • Guldberg, P.1    thor Straten, P.2    Birck, A.3    Ahrenkiel, V.4    Kirkin, A.F.5    Zeuthen, J.6
  • 11
    • 0030801275 scopus 로고    scopus 로고
    • Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
    • Rhei E, Kang L, Bogomolniy F, Federici MG, Borgen PI, Boyd J. Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res 1997;57:3657-9.
    • (1997) Cancer Res , vol.57 , pp. 3657-3659
    • Rhei, E.1    Kang, L.2    Bogomolniy, F.3    Federici, M.G.4    Borgen, P.I.5    Boyd, J.6
  • 13
    • 15444349266 scopus 로고    scopus 로고
    • Frequent inactivation of PTEN/MMAC1 in primary prostate cancer
    • Cairns P, Okami K, Halachmi S, et al. Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res 1997;57:4997-5000.
    • (1997) Cancer Res , vol.57 , pp. 4997-5000
    • Cairns, P.1    Okami, K.2    Halachmi, S.3
  • 14
    • 0032523808 scopus 로고    scopus 로고
    • Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors
    • Obata K, Morland SJ, Watson RH, et al. Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. Cancer Res 1998;58:2095-7.
    • (1998) Cancer Res , vol.58 , pp. 2095-2097
    • Obata, K.1    Morland, S.J.2    Watson, R.H.3
  • 15
    • 33748639077 scopus 로고    scopus 로고
    • Differential DNA methylation profiles in gynecological cancers and correlation with clinicopathological data
    • Yang HJ, Liu VW, Wang Y, Tsang PC, Ngan HY. Differential DNA methylation profiles in gynecological cancers and correlation with clinicopathological data. BMC Cancer 2006;6:212.
    • (2006) BMC Cancer , vol.6 , pp. 212
    • Yang, H.J.1    Liu, V.W.2    Wang, Y.3    Tsang, P.C.4    Ngan, H.Y.5
  • 16
    • 3042561633 scopus 로고    scopus 로고
    • Suppression of cell migration in ovarian cancer cells mediated by PTEN overexpression
    • Saga Y, Mizukami H, Takei Y, Ozawa K, Suzuki M. Suppression of cell migration in ovarian cancer cells mediated by PTEN overexpression. Int J Oncol 2003;23:1109-13.
    • (2003) Int J Oncol , vol.23 , pp. 1109-1113
    • Saga, Y.1    Mizukami, H.2    Takei, Y.3    Ozawa, K.4    Suzuki, M.5
  • 17
    • 0036096690 scopus 로고    scopus 로고
    • Overexpression of PTEN increases sensitivity to SN-38, an active metabolite of the topoisomerase I inhibitor irinotecan, in ovarian cancer cells
    • Saga Y, Mizukami H, Suzuki M, et al. Overexpression of PTEN increases sensitivity to SN-38, an active metabolite of the topoisomerase I inhibitor irinotecan, in ovarian cancer cells. Clin Cancer Res 2002;8:1248-52.
    • (2002) Clin Cancer Res , vol.8 , pp. 1248-1252
    • Saga, Y.1    Mizukami, H.2    Suzuki, M.3
  • 18
    • 0025161884 scopus 로고
    • Establishment and characterization of a human ovarian serous cystadenocarcinoma cell line that produces the tumor markers CA-125 and tissue polypeptide antigen
    • Imai S, Kiyozuka Y, Maeda H, Noda T, Hosick HL. Establishment and characterization of a human ovarian serous cystadenocarcinoma cell line that produces the tumor markers CA-125 and tissue polypeptide antigen. Oncology 1990;47:177-84.
    • (1990) Oncology , vol.47 , pp. 177-184
    • Imai, S.1    Kiyozuka, Y.2    Maeda, H.3    Noda, T.4    Hosick, H.L.5
  • 19
    • 0023157375 scopus 로고
    • Establishment of a human ovarian cancer cell line capable of forming ascites in nude mice and effects of tranexamic acid on cell proliferation and ascites formation
    • Kikuchi Y, Kizawa I, Oomori K, et al. Establishment of a human ovarian cancer cell line capable of forming ascites in nude mice and effects of tranexamic acid on cell proliferation and ascites formation. Cancer Res 1987;47:592-6.
    • (1987) Cancer Res , vol.47 , pp. 592-596
    • Kikuchi, Y.1    Kizawa, I.2    Oomori, K.3
  • 20
    • 0034777746 scopus 로고    scopus 로고
    • Expression of HGF/NK4 in ovarian cancer cells suppresses intraperitoneal dissemination and extends host survival
    • Saga Y, Mizukami H, Suzuki M, et al. Expression of HGF/NK4 in ovarian cancer cells suppresses intraperitoneal dissemination and extends host survival. Gene Ther 2001;8:1450-5.
    • (2001) Gene Ther , vol.8 , pp. 1450-1455
    • Saga, Y.1    Mizukami, H.2    Suzuki, M.3
  • 21
    • 8644279680 scopus 로고    scopus 로고
    • Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro
    • Takei Y, Mizukami H, Saga Y, et al. Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro. Int J Cancer 2005;113:54-8.
    • (2005) Int J Cancer , vol.113 , pp. 54-58
    • Takei, Y.1    Mizukami, H.2    Saga, Y.3
  • 22
    • 0036378727 scopus 로고    scopus 로고
    • Enhanced expression of thymidylate synthase mediates resistance of uterine cervical cancer cells to radiation
    • Saga Y, Suzuki M, Mizukami H, et al. Enhanced expression of thymidylate synthase mediates resistance of uterine cervical cancer cells to radiation. Oncology 2002;63:185-91.
    • (2002) Oncology , vol.63 , pp. 185-191
    • Saga, Y.1    Suzuki, M.2    Mizukami, H.3
  • 23
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • Kung AL, Wang S, Klco JM, et al. Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med 2000;6:1335-40.
    • (2000) Nat Med , vol.6 , pp. 1335-1340
    • Kung, A.L.1    Wang, S.2    Klco, J.M.3
  • 24
    • 0034100051 scopus 로고    scopus 로고
    • In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002)
    • Hu L, Zaloudek C, Mills GB, Gray J, Jaffe RB. In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002). Clin Cancer Res 2000;6:880-6.
    • (2000) Clin Cancer Res , vol.6 , pp. 880-886
    • Hu, L.1    Zaloudek, C.2    Mills, G.B.3    Gray, J.4    Jaffe, R.B.5
  • 25
    • 0042014500 scopus 로고    scopus 로고
    • Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer
    • Kohno T, Mizukami H, Suzuki M, et al. Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer. Cancer Res 2003;63:5091-4.
    • (2003) Cancer Res , vol.63 , pp. 5091-5094
    • Kohno, T.1    Mizukami, H.2    Suzuki, M.3
  • 26
    • 0042413371 scopus 로고    scopus 로고
    • In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin
    • Tanaka M, Grossman HB. In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin. Gene Ther 2003;10:1636-42.
    • (2003) Gene Ther , vol.10 , pp. 1636-1642
    • Tanaka, M.1    Grossman, H.B.2
  • 27
    • 0035935261 scopus 로고    scopus 로고
    • Suppression of tumorigenicity and metastasis in B16F10 cells by PTEN/MMAC1/TEP1 gene
    • Hwang PH, Yi HK, Kim DS, Nam SY, Kim JS, Lee DY. Suppression of tumorigenicity and metastasis in B16F10 cells by PTEN/MMAC1/TEP1 gene. Cancer Lett 2001;172:83-91.
    • (2001) Cancer Lett , vol.172 , pp. 83-91
    • Hwang, P.H.1    Yi, H.K.2    Kim, D.S.3    Nam, S.Y.4    Kim, J.S.5    Lee, D.Y.6
  • 28
    • 0037192768 scopus 로고    scopus 로고
    • PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects
    • Huang J, Kontos CD. PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects. J Biol Chem 2002;277:10760-6.
    • (2002) J Biol Chem , vol.277 , pp. 10760-10766
    • Huang, J.1    Kontos, C.D.2
  • 29
    • 0036731001 scopus 로고    scopus 로고
    • Koul D, Shen R, Garyali A, Ke LD, Liu TJ, Yung WK. MMAC/PTEN tumor suppressor gene regulates vascular endothelial growth factor-mediated angiogenesis in prostate cancer. Int J Oncol 2002;21:469-75.
    • Koul D, Shen R, Garyali A, Ke LD, Liu TJ, Yung WK. MMAC/PTEN tumor suppressor gene regulates vascular endothelial growth factor-mediated angiogenesis in prostate cancer. Int J Oncol 2002;21:469-75.
  • 30
    • 0032475861 scopus 로고    scopus 로고
    • Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
    • Stambolic V, Suzuki A, de la Pompa JL, et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 1998;95:29-39.
    • (1998) Cell , vol.95 , pp. 29-39
    • Stambolic, V.1    Suzuki, A.2    de la Pompa, J.L.3
  • 31
    • 0035328703 scopus 로고    scopus 로고
    • Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN
    • Matsushima-Nishiu M, Unoki M, Ono K, et al. Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN. Cancer Res 2001;61:3741-9.
    • (2001) Cancer Res , vol.61 , pp. 3741-3749
    • Matsushima-Nishiu, M.1    Unoki, M.2    Ono, K.3
  • 32
    • 33745987641 scopus 로고    scopus 로고
    • Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner
    • Yan X, Fraser M, Qiu Q, Tsang BK. Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner. Gynecol Oncol 2006;102:348-55.
    • (2006) Gynecol Oncol , vol.102 , pp. 348-355
    • Yan, X.1    Fraser, M.2    Qiu, Q.3    Tsang, B.K.4
  • 33
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983;219:983-5.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 34
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
    • Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995;146:1029-39.
    • (1995) Am J Pathol , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    Dvorak, A.M.4
  • 35
    • 13244251091 scopus 로고    scopus 로고
    • Inhibition of peritoneal dissemination of ovarian cancer by tyrosine kinase receptor inhibitor SU6668 (TSU-68)
    • Machida S, Saga Y, Takei Y, et al. Inhibition of peritoneal dissemination of ovarian cancer by tyrosine kinase receptor inhibitor SU6668 (TSU-68). Int J Cancer 2005;114:224-9.
    • (2005) Int J Cancer , vol.114 , pp. 224-229
    • Machida, S.1    Saga, Y.2    Takei, Y.3
  • 36
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003;349:427-34.
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 37
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F, Hurwitz HI, Fehrenbacher L, et al. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003;21:60-5.
    • (2003) J Clin Oncol , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3
  • 38
    • 10844295093 scopus 로고    scopus 로고
    • Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor
    • Mahendra G, Kumar S, Isayeva T, et al. Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor. Cancer Gene Ther 2005;12:26-34.
    • (2005) Cancer Gene Ther , vol.12 , pp. 26-34
    • Mahendra, G.1    Kumar, S.2    Isayeva, T.3
  • 39
    • 2442640516 scopus 로고    scopus 로고
    • Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer
    • Sako A, Kitayama J, Koyama H, et al. Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer. Cancer Res 2004;64:3624-8.
    • (2004) Cancer Res , vol.64 , pp. 3624-3628
    • Sako, A.1    Kitayama, J.2    Koyama, H.3
  • 40
    • 0034626708 scopus 로고    scopus 로고
    • MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells
    • Tanaka M, Koul D, Davies MA, Liebert M, Steck PA, Grossman HB. MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells. Oncogene 2000;19:5406-12.
    • (2000) Oncogene , vol.19 , pp. 5406-5412
    • Tanaka, M.1    Koul, D.2    Davies, M.A.3    Liebert, M.4    Steck, P.A.5    Grossman, H.B.6
  • 41
    • 0034671472 scopus 로고    scopus 로고
    • Derivation and initial characterization of a mouse mammary tumor cell line carrying the polyomavirus middle T antigen: Utility in the development of novel cancer therapeutics
    • Nielsen LL, Gurnani M, Shi B, et al. Derivation and initial characterization of a mouse mammary tumor cell line carrying the polyomavirus middle T antigen: utility in the development of novel cancer therapeutics. Cancer Res 2000;60:7066-74.
    • (2000) Cancer Res , vol.60 , pp. 7066-7074
    • Nielsen, L.L.1    Gurnani, M.2    Shi, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.