Rapid media transition: An experimental approach for steady state analysis of metabolic pathways

Biotechnology Progress

Volumn 26, Issue 1, 2010, Pages 1-10

  Link, Hannes ^a   Anselment, Bernd ^a   Weuster Botz, Dirk ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Fed batch process; Metabolic flux analysis; Metabolome analysis; Steady state perturbation

Indexed keywords

BIOPROCESSES; CARBON SOURCE; CHEMOSTAT CULTURE; CONTINUOUS CULTURE; ENVIRONMENTAL CONDITIONS; EXPERIMENTAL APPROACHES; EXPERIMENTAL SETUP; EXTRACELLULAR; FED BATCHES; FED-BATCH PROCESS; INDUSTRIAL BIOPROCESSES; MEDIA TRANSITION; METABOLIC FLUX ANALYSIS; METABOLIC PATHWAYS; METABOLITE CONCENTRATIONS; METABOLOME ANALYSIS; METABOLOMES; MICROBIAL METABOLISM; NEW APPROACHES; NON-STATIONARY CONDITION; PHYSIOLOGICAL CONDITION; PRODUCTION PROCESS; PYRUVATES; STEADY STATE; STEADY-STATE ANALYSIS; STIRRED TANK REACTORS; TIME-SCALES;

BATCH DATA PROCESSING; CELL CULTURE; ENZYME ACTIVITY; ESCHERICHIA COLI; GLUCOSE;

METABOLISM;

ACETIC ACID DERIVATIVE; CARBON; GLUCOSE; PYRUVIC ACID; SUCCINIC ACID;

ARTICLE; BIOMASS; BIOREACTOR; CULTURE MEDIUM; CYTOLOGY; ESCHERICHIA COLI K 12; GROWTH, DEVELOPMENT AND AGING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; TIME;

ACETATES; BACTERIOLOGICAL TECHNIQUES; BIOMASS; BIOREACTORS; CARBON; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CULTURE MEDIA; ESCHERICHIA COLI K12; GLUCOSE; MASS SPECTROMETRY; METABOLIC NETWORKS AND PATHWAYS; PYRUVIC ACID; SUCCINIC ACID; TIME FACTORS;

ESCHERICHIA COLI;

EID: 76849096152     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.290     Document Type: Article

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