Co-response analysis: A new experimental strategy for metabolic control analysis

Journal of Theoretical Biology

Volumn 182, Issue 3, 1996, Pages 371-380

  Hofmeyr, Jan Hendrik S ^a   Cornish Bowden, Athel ^b  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME;

ENZYME ACTIVITY; ENZYME REGULATION; METABOLIC REGULATION; PRIORITY JOURNAL; REVIEW; STOICHIOMETRY;

EID: 0030574092     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1996.0176     Document Type: Article

References (34)

1. ACERENZA, L. (1993). Metabolic control design. J. theor. Biol. 165, 63-85.
2. ACERENZA, L. (1996). How constrained is metabolic control? J. theor. Biol. 182, 277-283.
3. BROWN, G. C., HAFNER, R. P. & BRAND, M. D. (1990). A "top-down" approach to the determination of control coefficients in metabolic control theory. Eur. J. Biochem. 188, 321-325.
4. CASCANTE, M., FRANCO, R. & CANELA, E. I. (1989a). Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. 1. Unbranched pathways. Math. Biosci. 94, 271-288.
5. CASCANTE, M., FRANCO, R. & CANELA, E. I. (1989b). Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. 2. Complex systems. Math. Biosci. 94, 289-309.
6. CORNISH-BOWDEN, A. & HOFMEYR, J.-H. S. (1991). A program for the modelling and control analysis of metabolic pathways on the IBM PC and compatibles. Comp. Appl. Biosci. 7, 89-93.
7. CORNISH-BOWDEN, A. & HOFMEYR, J.-H. S. (1994). Determination of control coefficients in intact metabolic systems. Biochem. J. 298, 367-375.
8. FELL, D. A. & SAURO, H. M. (1985). Metabolic control analysis: Additional relationships between elasticities and control coefficients. Eur. J. Biochem. 148, 555-561.
9. FELL, D. A., SAURO, H. M. & SMALL, J. R. (1990). Control coefficients and the matrix method. In: Control of Metabolic Processes (Cornish-Bowden, A. & Cárdenas, M. L., eds), pp. 139-148. New York: Plenum Press.
10. GIERSCH, C. (1988). Control analysis of biochemical pathways. J. theor. Biol. 134, 451-462.
11. GIERSCH, C. (1994). Determining elasticities from multiple measurement of steady-state flux rates and metabolite concentrations: Theory. J. theor. Biol. 169, 89-99.
12. GIERSCH, C. (1995). Determining elasticities from multiple measurement of steady-state flux rates and metabolite concentrations: Applications of the multiple modulation method to a reconstituted pathway. Eur. J. Biochem. 227, 194-201.
13. GIERSCH, C. & CORNISH-BOWDEN, A. (1996). Extending double modulation: Combinatorial rules for identifying the modulations necessary for determining the elasticities in metabolic pathways. J. theor. Biol. 182, 361-369.
14. HEINRICH, R. & REDER, C. (1991). Metabolic control analysis of relaxation processes. J. theor. Biol. 151, 343-350.
15. HOFMEYR, J.-H. S. & CORNISH-BOWDEN, A. (1991). Quantitative assessment of regulation in metabolic systems. Eur. J. Biochem. 200, 223-236.
16. HOFMEYR, J.-H. S. & CORNISH-BOWDEN, A. (1993). A control analysis of metabolic regulation. In: Modern Trends in BioThermoKinetics (Schuster, S., Rigoulet, M., Ouhabi, R. & Mazat, J., eds), Vol. 2, pp. 193-198. New York: Plenum Press.
17. HOFMEYR, J.-H. S. & CORNISH-BOWDEN, A. (1994). How should we quantify metabolic regulation? In: Modern Trends in BioThermoKinetics (Gnaiger, E., Gellerich, F. N. & Wyss, M., eds), Vol. 3, pp. 91-94. Innsbruck: Innsbruck University Press.
18. HOFMEYR, J.-H. S., CORNISH-BOWDEN, A. & ROHWER, J. M. (1993). Taking enzyme kinetics out of control: Putting control into regulation. Eur. J. Biochem. 212, 833-837.
19. HOFMEYR, J.-H. S., KACSER, H. & VAN DER MERWE, K. J. (1986). Metabolic control analysis of moiety-conserved cycles. Eur. J. Biochem. 155, 631-641.
20. HOFMEYR, J.-H. S. (1995). Metabolic regulation: A control analytic perspective. J. Bioenerg. Biomembranes 27, 479-489.
21. KACSER, H. (1956). Molecular organization of genetic material. Science 124, 151-154.
22. KACSER, H. & BURNS, J. A. (1973). The control of flux. Symp. Soc. Exp. Biol. 32, 65-104.
23. KACSER, H. & BURNS, J. (1979). Molecular democracy: Who shares the controls? Biochem. Soc. Trans. 7, 1149-1160.
24. KACSER, H., SAURO, H. M. & ACERENZA, L. (1990). Enzyme-enzyme interaction and control analysis. 1. The case of non-additivity: Monomer-oligomer associations. Eur. J. Biochem. 187, 481-491.
25. KAHN, D. & WESTERHOFF, H. V. (1991). Control theory of regulatory cascades. J. theor. Biol. 153, 255-285.
26. KHOLODENKO, B. N. (1988). How do external parameters control fluxes and concentrations of metabolites? An additional relationship in the theory of metabolic control. FEBS Lett. 232, 383-386.
27. REDER, C. (1988). Metabolic control theory: a structural approach. J. theor. Biol. 135, 175-201.
28. ROHWER, J. M., SCHUSTER, S. & WESTERHOFF, H. V. (1996). How to recognise monofunctional units in a metabolic system. J. theor. Biol. 179, 213-228.
29. SAURO, H. (1993). SCAMP: A general-purpose simulator and metabolic control analysis program. Comp. Appl. Biosci. 9, 441-450.
30. SAURO, H. M. & KACSER, H. (1990). Enzyme-enzyme interaction and control analysis. 2. The case of non-independence: Heterologous associations. Eur. J. Biochem. 187, 493-500.
31. SAURO, H. M., SMALL, J. R. & FELL, D. A. (1987). Metabolic control and its analysis: Extensions to the theory and matrix method. Eur. J. Biochem. 165, 215-221.
32. SCHUSTER, S., KAHN, D. & WESTERHOFF, H. V. (1993). Modular analysis of the control of complex metabolic pathways. Biophys. Chem. 48, 1-17.
33. SMALL, J. R. & FELL, D. A. (1989). The matrix method of control analysis: Its validity for complex pathway structures. J. theor. Biol. 136, 181-197.
34. WESTERHOFF, H. V. & KELL, D. B. (1987). Matrix method for determining steps most rate-limiting to flux in biotechnological processes. Biotechnol. Bioeng. 30, 101-107.