Intrinsically resolution enhancing probes for confocal microscopy

Nano Letters

Volumn 10, Issue 2, 2010, Pages 672-679

  Vogelsang, Jan ^a   Cordes, Thorben ^a   Forthmann, Carsten ^a   Steinhauer, Christian ^a   Tinnefeld, Philip ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Excited state saturation; FRET; Nonlinear fluorescence; Single molecule spectroscopy; Superresolution microscopy

Indexed keywords

CONFOCAL MICROSCOPES; DIFFRACTION BARRIER; EXCITATION INTENSITY; EXCITED-STATE SATURATION; FLUORESCENT PROBES; INTENSITY-DEPENDENT; KEY ELEMENTS; MOLECULAR STATE; NON-LINEARITY; PROOF-OF-PRINCIPLE EXPERIMENTS; QUANTITATIVE DESCRIPTION; RADICAL ANIONS; RESONANCE ENERGY TRANSFER; SINGLE-MOLECULE SPECTROSCOPY; SUPER-RESOLUTION MICROSCOPY; THEORETICAL MODELS; THREE DIMENSIONS;

CONFOCAL MICROSCOPY; ENERGY TRANSFER; EXCITED STATES; FLUOROPHORES; OPTICAL RESOLVING POWER;

PROBES;

ANION; BIOTIN; BOVINE SERUM ALBUMIN; FLUORESCENT DYE;

ANIMAL; ARTICLE; BIOPHYSICS; CATTLE; CHEMISTRY; CONFOCAL MICROSCOPY; ENERGY TRANSFER; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; INSTRUMENTATION; LIGHT; METHODOLOGY; NORMAL DISTRIBUTION; STATISTICAL MODEL;

ANIMALS; ANIONS; BIOPHYSICS; BIOTIN; CATTLE; ENERGY TRANSFER; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; LIGHT; MICROSCOPY, CONFOCAL; MODELS, STATISTICAL; NORMAL DISTRIBUTION; SERUM ALBUMIN, BOVINE;

EID: 76749128978     PISSN: 15306984     EISSN: 15306992     Source Type: Journal    
DOI: 10.1021/nl903823s     Document Type: Article

References (45)

1. Hell, S. W. Far-field optical nanoscopy. Science 2007, 316 (5828), 1153-1158.
2. Fernandez-Suarez, M.; Ting, A. Y. Fluorescent probes for superresolution imaging in living cells. Nat. Rev. Mol. Cell Biol 2008, 9 (12), 929-943
3. Huang, B.; Bates, M.; Zhuang, X. Super-resolution fluorescence microscopy. Annu. Rev. Biochem. 2009, 78, 993-1016.
4. Ji, N.; Shroff, H.; Zhong, H.; Betzig, E. Advances in the speed and resolution of light microscopy. Curr. Opin. Neurobiol. 2008, 18 (6), 605-616
5. Hell, S. W. Microscopy and its focal switch. Nat. Methods 2009, 6 (1), 24-32.
6. Hell, S. W. Strategy for far-field optical imaging and writing without diffraction limit. Phys. Lett. A 2004, 326 (1-2), 140-145.
7. Hell, S. W. Toward fluorescence nanoscopy. Nat. Biotechnol. 2003, 21 (11), 1347-1355.
8. Hell, S.W.; Dyba, M.; Jakobs, S. Concepts for nanoscale resolution in fluorescence microscopy. Curr. Opin. Neurobiol. 2004, 14 (5), 599-609. (Pubitemid 39359176)
9. Schonle, A.; Hanninen, P. E.; Hell, S. W. Nonlinear fluorescence through intermolecular energy transfer and resolution increase in fluorescence microscopy. Ann. Phys. 1999, 8 (2), 115-133.
10. Heintzmann, R.; Gustafsson, M. G. L. Subdiffraction resolution in continuous samples. Nat. Photon. 2009, 3 (7), 362-364.
11. Klar, T. A.; Jakobs, S.; Dyba, M.; Egner, A.; Hell, S. W. Fluorescence microscopy with diffraction resolution barrier broken by stimulated emission. Proc. Natl. Acad. Sci. U.S.A. 2000, 97 (15), 8206-8210. (Pubitemid 30639649)
12. Gustafsson, M. G. L. Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution.Proc. Natl. Acad. Sci. U.S.A. 2005, 102(37), 13081-13086.
13. Heintzmann, R.; Jovin, T. M.; Cremer, C. Saturated patterned excitation microscopy - a concept for optical resolution improvement J. Opt. Soc. Am. A 2002, 19 (8), 1599-1609.
14. Bretschneider, S.; Eggeling, C.; Hell, S. W. Breaking the diffraction barrier in fluorescence microscopy by optical shelving. Phys. Rev. Lett. 2007, 98 (21), 218103.
15. Betzig, E.; Patterson, G. H.; Sougrat, R.; Lindwasser, O. W.; Olenych, S.; Bonifacino, J. S.; Davidson, M. W.; Lippincott-Schwartz, J.; Hess, H. F. Imaging intracellular fluorescent proteins at nanometer resolution. Science 2006, 313 (5793), 1642-1645. (Pubitemid 44414039)
16. Rust, M. J.; Bates, M.; Zhuang, X. Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat Methods 2006, 3 (10), 793-795 (Pubitemid 44445825)
17. Hess, S. T.; Girirajan, T. P.; Mason, M. D. Ultra-high resolution imaging by fluorescence photoactivation localization microscopy. Biophys. J. 2006, 91 (11), 4258-4272
18. Heilemann, M.; van de Linde, S.; Schuttpelz, M.; Kasper, R.; Seefeldt, B.; Mukherjee, A.; Tinnefeld, P.; Sauer, M. Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes. Angew. Chem., Int. Ed. 2008, 47 (33), 6172-6176.
19. Foiling, J.; Bossi, M.; Bock, H.; Medda, R.; Wurm, C. A.; Hein, B.; Jakobs, S.; Eggeling, C.; Hell, S. W. Fluorescence nanoscopy by ground-state depletion and single-molecule return. Nat. Methods 2008, 5 (11), 943-945
20. Steinhauer, C.; Forthmann, C.; Vogelsang, J.; Tinnefeld, P. Superresolution microscopy on the basis of engineered dark states. J. Am. Chem. Soc. 2008, 130 (50), 16840-16841.
21. Rittweger, E.; Han, K. Y.; Irvine, S. E.; Eggeling, C.; Hell, S. W. STED microscopy reveals crystal colour centres with nanometric resolution. Nat. Photon. 2009, 3 (3), 144-147.
22. Vogelsang, J.; Kasper, R.; Steinhauer, C.; Person, B.; Heilemann, M.; Sauer, M.; Tinnefeld, P. A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes. Angew. Chem., Int. Ed. 2008, 47, 5465-5469.
23. Hanninen, P. E.; Lehtela, L.; Hell, S. W. Two- and multiphoton excitation of conjugate-dyes using a continuous wave laser. Opt. Commun. 1996, 130 (1-3), 29-33.
24. Denk, W.; Strickler, J. H.; Webb, W. W. Two-photon laser scanning fluorescence microscopy. Science (Washington, DC, U. S.) 1990, 248 (4951), 73-76 (Pubitemid 20139273)
25. Hennig, S.; van de Linde, S.; Heilemann, M.; Sauer, M. Quantum Dot Triexciton Imaging with Three-Dimensional Subdiffraction Resolution. Nano Lett. 2009, 9 (6), 2466-2470.
26. Berglund, A. J.; Doherty, A. C.; Mabuchi, H. Photon statistics and dynamics of fluorescence resonance energy transfer. Phys. Rev. Lett. 2002, 89 (6), 068101-1-068101-68104
27. Melnikov, S. M.; Yeow, E. K. L.; Uji-i, H.; Cotlet, M.; Mullen, K.; De Schryver, F. C.; Enderlein, J.; Hofkens, J. Origin of simultaneous donor-acceptor emission in single molecules of peryleneimide-terrylenediimide labeled polyphenylene dendrimers. J. Phys. Chem. B 2007, 111 (4), 708-719. (Pubitemid 46266329)
28. Hofkens, J.; Cotlet, M.; Vosch, T.; Tinnefeld, P.; Weston, K. D.; Ego, C.; Grimsdale, A.; Muellen, K.; Beljonne, D.; Bredas, J. L.; Jordens, S.; Schweitzer, G.; Sauer, M.; De Schryver, F. Revealing competitive Foerster-type resonance energy-transfer pathways in single bichromophoric molecules. Proc. Natl. Acad. Sci. U.S.A. 2003, 100 (23), 13146-13151. (Pubitemid 37444709)
29. Vosch, T.; Cotlet, M.; Hofkens, J.; Van Biest, K.; Lor, M.; Weston, K.; Tinnefeld, P.; Sauer, M.; Latterini, L.; Muellen, K.; De Schryver, F. C. Probing Foerster Type Energy Pathways in a First Generation Rigid Dendrimer Bearing Two Perylene Imide Chromophores J. Phys. Chem. A 2003, 107 (36), 6920-6931.
30. Gopich, I.; Szabo, A. Theory of photon statistics in single-molecule Forster resonance energy transfer. J. Chem. Phys. 2005, 122 (1), No.0147071-01470718.
31. Tinnefeld, P.; Buschmann, V.; Weston, K. D.; Biebricher, A.; Herten, D.-P.; Piestert, O.; Heinlein, T.; Heilemann, M.; Sauer, M. How single molecule photophysical studies complement ensemble methods for a better understanding of chromophores and chromophore interactions. Recent Res. Dev. Phys. Chem. 2004, 7(Pt. 1), 95-125.
32. Tinnefeld, P.; Buschmann, V.; Weston, K. D.; Sauer, M. Direct observation of collective blinking and energy transfer in a bichromophoric system J. Phys. Chem. A 2003, 107 (3), 323-327.
33. Kandori, H.; Kemnitz, K.; Yoshihara, K. Subpicosecond Transient Absorption Study of Intermolecular Electron-Transfer between Solute and Electron-Donating Solvents J. Phys. Chem. 1992, 96 (20), 8042-8048.
34. Chibisov, A. K. Triplet-States of Cyanine Dyes and Reactions of Electron-Transfer with Their Participation J. Photochem. 1977, 6 (3), 199-214.
35. Korobov, V. E.; Chibisov, A. K. Primary Processes in Photochemistry of Rhodamine Dyes J. Photochem. 1978, 9 (5), 411-424.
36. Vogelsang, J.; Cordes, T.; Forthmann, C.; Steinhauer, C.; Tinnefeld, P. Controlling the fluorescence of ordinary oxazine dyes for single-molecule switching and superresolution microscopy. Proc. Natl. Acad. Sci. U.S.A. 2009, 106 (20), 8107-8112.
37. Harada, Y.; Sakurada, K.; Aoki, T.; Thomas, D. D.; Yanagida, T. Mechanochemical Coupling in Actomyosin Energy Transduction Studied By Invitro Movement Assay. J. Mol. Biol. 1990, 216 (1), 49-68.
38. Cordes, T.; Vogelsang, J.; Tinnefeld, P. On the mechanism of trolox as antiblinking and antibleaching reagent J. Am. Chem. Soc. 2009, 131 (14), 5018-5019.
39. Metivier, R.; Nolde, F.; Müllen, K.; Basche, T. Electronic Excitation Energy Transfer between Two Single Molecules Embedded in a Polymer Host. Phys. Rev. Lett. 2007, 98 (4), 47802. (Pubitemid 46168670)
40. Bewersdorf, J.; Schmidt, R.; Hell, S. W. Comparison of (IM)-M-5 and 4Pi-microscopy. J. Microsc. (Oxford, U.K.) 2006, 222, 105-117.
41. Cotlet, M.; Gronheid, R.; Habuchi, S.; Stefan, A.; Barbafina, A.; Muellen, K.; Hofkens, J.; De Schryver, F. C. Intramolecular Directional Foerster Resonance Energy Transfer at the Single-Molecule Level in a Dendritic System J. Am. Chem. Soc. 2003, 125 (44), 13609-13617.
42. Cotlet, M.; Vosch, T.; Habuchi, S.; Weil, T.; Muellen, K.; Hofkens, J.; De Schryver, F. Probing Intramolecular Foerster Resonance Energy Transfer in a Naphthaleneimide-Peryleneimide-Terrylenediimide-Based Dendrimer by Ensemble and Single-Molecule Fluorescence Spectroscopy. J. Am. Chem. Soc. 2005, 127 (27), 9760-9768. (Pubitemid 40981539)
43. Heilemann, M.; Kasper, R.; Tinnefeld, P.; Sauer, M. Dissecting and reducing the heterogeneity of excited-state energy transport in DNA-based photonic wires. J. Am. Chem. Soc. 2006, 128 (51), 16864-16875
44. Espenel, C.; Margeat, E.; Dosset, P.; Arduise, C.; Le Grimellec, C.; Royer, C. A.; Boucheix, C.; Rubinstein, E.; Milhiet, P. E. Singlemolecule analysis of CD9 dynamics and partitioning reveals multiple modes of interaction in the tetraspanin web. J. Cell Biol. 2008, 182 (4), 765-776.
45. Marriott, G.; Mao, S.; Sakata, T.; Ran, J.; Jackson, D. K.; Petchprayoon, C.; Gomez, T. J.; Warp, E.; Tulyathan, O.; Aaron, H. L.; Isacoff, E. Y.; Yan, Y. L. Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells. Proc. Natl. Acad. Sci. U.S.A. 2008, 105 (46), 17789-17794.