Construction and testing of engineered zinc-finger proteins for sequence-specific modification of mtDNA

Nature Protocols

Volumn 5, Issue 2, 2010, Pages 342-356

  Minczuk, Michal ^a   Kolasinska Zwierz, Paulina ^b,c   Murphy, Michael P ^a   Papworth, Monika A ^b,d  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A; MITOCHONDRIAL DNA; NONSTRUCTURAL PROTEIN 2; PLASMID DNA; PROTEINASE K; ZINC FINGER PROTEIN;

ARTICLE; DNA BINDING; DNA SEQUENCE; GENE CONSTRUCT; HETEROPLASMY; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN ENGINEERING; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BASE SEQUENCE; DNA PROBES; DNA, MITOCHONDRIAL; GENETIC ENGINEERING; GENOME, MITOCHONDRIAL; MUTAGENESIS; OLIGODEOXYRIBONUCLEOTIDES; PLASMIDS; ZINC FINGERS;

MAMMALIA;

EID: 76649126393     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2009.245     Document Type: Article

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