Downregulation of protein kinase C- αenhances intracellular survival of Mycobacteria: Role of PknG

BMC Microbiology

Volumn 9, Issue , 2009, Pages

  Chaurasiya, Shivendra K ^a   Srivastava, Kishore K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE C ALPHA; VIRULENCE FACTOR;

ARTICLE; BACTERIAL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; MACROPHAGE FUNCTION; MYCOBACTERIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; PROTEIN EXPRESSION; CELL LINE; CYTOSOL; DRUG ANTAGONISM; HOST PATHOGEN INTERACTION; IMMUNOLOGY; MACROPHAGE; MICROBIAL VIABILITY; MICROBIOLOGY; MYCOBACTERIUM SMEGMATIS; PATHOGENICITY; PHYSIOLOGY;

CORYNEBACTERINEAE; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

CELL LINE; CYCLIC GMP-DEPENDENT PROTEIN KINASES; CYTOSOL; DOWN-REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; MACROPHAGES; MICROBIAL VIABILITY; MYCOBACTERIUM BOVIS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; PROTEIN KINASE C-ALPHA; VIRULENCE FACTORS;

EID: 76649111379     PISSN: 14712180     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-9-271     Document Type: Article

References (37)

1. Interplay between mycobacteria and host signalling pathways. A Koul T Herget B Klebl A Ullrich, Nat Rev Microbiol 2004 2 189 202 10.1038/nrmicro840 15083155
2. 2+ signaling by Mycobacterium tuberculosis is associated with reduced phagosome-lysosome fusion an d increased survival within human macrophages. ZA Malik GM Denning DJ Kusner, J Exp Med 2000 191 287 302 10.1084/jem.191.2.287 10637273
3. Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction: contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages. ZA Malik SS Iyer DJ Kusner, J Immunol 2001 166 3392 3401 11207296
4. MAP kinase activation in macrophages. KMK Rao, J Leukoc Biol 2001 69 3 10 11200064
5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. ST Cole R Brosch J Parkhill T Garnier C Churcher D Harris SV Gordon K Eiglmeier S Gas CE Barry F Tekaia K Badcock D Basham D Brown T Chillingworth T Connor R Davies K Devlin T Feltwell S Gentles N Hamlin S Holroyd T Hornsby K Jagels A Krogh J McLean S Moule L Murphy K Oliver J Osborne MA Quail MA Rajandream J Rogers S Rutter K Seeger J Skelton R Squares S Squares JE Sulston K Taylor Whitehead BG Barrell, Nature 1998 393 537 544 10.1038/31159 9634230
6. The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. Y Av-Gay M Everett, Trends Microbiol 2000 8 238 244 10.1016/S0966-842X(00)01734-0 10785641
7. Differential regulation of the mitogen-activated protein kinases by pathogenic and nonpathogenic mycobacteria. SK Roach JS Schorey, Infect Immun 2002 70 3040 3052 10.1128/IAI.70.6.3040-3052.2002 12010996
8. Macrophage signaling upon mycobacterial infection:the map kinases lead the way. JS Schorey AM Cooper, Cell Microbiol 2003 5 133 142 10.1046/j.1462-5822.2003.00263.x 12614457
9. Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. A Walburger A Koul G Ferrari L Nguyen C Prescianotto-Baschong K Huygen B Klebl C Thompson G Bacher J Pieters, Science 2004 304 1800 1804 10.1126/science.1099384 15155913
10. Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis. BLJ Webb SJ S Hirst MA Giembycz, Br J Pharmacol 2000 130 1433 1452 10.1038/sj.bjp.0703452 10928943
11. Engagement of protein kinase C-theta in interferon signaling in T-cells. KK Srivastava S Batra A Sassano Y Li B Majchrzak H Kiyokawa A Altman EN Fish LC Platanias, J Biol Chem 2004 279 29911 29920 10.1074/jbc.M401997200 15150272
12. Immunoglobulin-mediated phagocytosis by human monocytes requires protein kinase C activation. A Zheleznyak EJ Brown, J Biol Chem 1992 267 1242 1248
13. Role of protein kinase C- for uptake of unopsonized prey and phagosomal maturation in macrophages. A Holm K Tejle T Gunnarsson KE Magnusson A Descoteaux B Rasmusson, Biochem 2003 302 653 658
14. Role of protein kinase C- in the control of infection by intracellular pathogens in macrophages. A St-denis V Caouras F Gervais A Descoteaux, J Immunol 1999 163 5505 5511 10553077
15. Proteomic analysis reveals a role for protein kinase C- in phagosome maturation. DJN Yan Hing M Desjardins A Descoteaux, Biochem Biophys Res Commun 2004 319 810 816 10.1016/j.bbrc.2004.05.054 15184055
16. A Role for MARCKS, the isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages. LH Allen A Aderem, J Exp Med 1995 182 829 840 10.1084/jem.182.3.829 7650489
17. The role of protein kinase C in the transient association of p57, a coronin family actin-binding protein, with phagosomes. S Itoh K Suzuki J Nishihata M Iwasa T Oku S Nakajin WM Nauseef S Toyoshima, Biol Pharm Bull 2002 25 837 844 10.1248/bpb.25.837 12132654
18. Differential regulation of protein kinase C isoforms of macrophages by pathogenic and non-pathogenic mycobacteria. SK Chaurasiya KK Srivastava, Mol Cell Biochem 2008 318 167 74 10.1007/s11010-008-9866-6 18649046
19. Differences in uptake of mycobacteria by human monocytes: a role for complement. RP Swartz D Naai CW Vogel H Yeager, Infect Immun 1988 56 2223 2227 3137162
20. Protein kinase C- participates in FcR-mediated phagocytosis in macrophages. A Breton A Descoteaux, Biochem Biophys Res Commun 2000 276 472 476 10.1006/bbrc.2000.3511 11027499
21. Phenotypic difference between Bcg(r) and Bcg(s) macrophages is related to differences in protein-kinase-C-dependent signaling. M Olivier P Cook J Desanctis Z Hel W Wojciechowski NE Reiner E Skamene D Radzioch, Eur J Biochem 1998 251 734 743 10.1046/j.1432-1327.1998.2510734.x 9490047
22. Encapsulated streptococcus suis inhibits activation of signaling pathways involved in phagocytosis. M Segura M Gottschalk M Olivier, Infect Immun 2004 72 5322 5330 10.1128/IAI.72.9.5322-5330.2004 15322029
23. Leishmania donovani lipophosphoglycan causes periphagosomal actin accumulation:correlation with impaired translocation of PKCα- and defective phagosome maturation. A Holm K Tejle KE Magnusson A Descoteaux B Rasmusson, Cell Microbiol 2001 3 439 447 10.1046/j.1462-5822.2001.00127.x 11437830
24. Identification of Mycobacterium tuberculosis clinical isolates with altered phagocytosis by human macrophages due to a truncated lipoarabinomannan. JB Torrelles R Knaup A Kolareth T Slepushkina TM Kaufman P Kang PJ Hill PJ Brennan D Chatterjee JY Belisle JM Musser LS Schlesinger, J Biol Chem 2008 283 31417 31428 10.1074/jbc.M806350200 18784076
25. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. JD Thompson GD Higgins TJ Gibson, Nucleic Acids Res 1994 22 4673 4680 10.1093/nar/22.22.4673 7984417
26. A coat protein on phagosomes involved in the intracellular survival of mycobacteria. G Ferrari H Langen M Naito J Pieters, Cell 1999 97 435 447 10.1016/S0092-8674(00)80754-0 10338208
27. Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin. R Jayachandran V Sundaramurthy B Combaluzier P Mueller H Korf K Huygen T Miyazaki I Albrecht J Massner Pieters, Cell 2007 130 37 50 10.1016/j.cell.2007.04.043 17632055
28. Differential expression of a virulence factor in pathogenic and nonpathogenic mycobacteria. EN Houben A Walburger G Ferrari L Nguyen CG Thompson C Miess G Vogel B Mueller J Pieters, Mol Microbiol 2009 72 41 52 10.1111/j.1365-2958.2009.06612.x 19210624
29. Dephosphorylation of activated protein kinase C contributes to downregulation by bryostatin. H Lee L Smith GR Pettit JB Smith, Am J Physio 1996 271 304 311
30. Regulation of glutamate metabolism by protein kinases in Mycobacteria. HM O'Hare R Duran C Cervẽansky M Bellinzoni AM Wehenkel O Pritsch G Obal J Baumgartner J Vialaret K Johnsson PM Alzari, Mol Microbiol 2008 70 1408 1423 10.1111/j.1365-2958.2008.06489.x 19019160
31. The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo. S Cowley M Ko N Pick R Chow KJ Downing BG Gordhan JC Betts V Mizrahi DA Smith RW Stokes Y Av-Gay, Mol Microbiol 2004 52 1691 1702 10.1111/j.1365-2958. 2004.04085.x 15186418
32. The Leishmania Surface Protease GP63 Cleaves Multiple Intracellular Proteins and Actively Participates in p38 Mitogen-activated Protein Kinase Inactivation. M Halle MA Gomez M Stuible H Shimizu WR McMaster M Olivier ML Tremblay, J Biol Chem 2009 284 6893 6908 10.1074/jbc.M805861200 19064994
33. Macrophage Phenotype Determines the Nonopsonic Binding of Mycobacterium tuberculosis to Murine Macrophages. RW Stokes ID Haidl WA Jefferies DP Speert, J Immunol 1993 151 7067 7076 8258711
34. Surface-exposed glyAcopeptidolipids of Mycobacterium smegmatis specifically inhibit the phagocytosis of mycobacteria by human macrophages. C Villeneuve G Etienne V Abadie H Montrozier C Bordier F Laval M Daffe I Maridonneau-Parini C Astarie-Dequeke, J Biol Chem 2003 278 51291 51300 10.1074/jbc.M306554200 14534313
35. Identification of Mycobacterium avium pathogenicity island important for macrophage and amoeba infection. L Danelishvili M Wu B Stang M Harriff S Cirillo J Cirillo R Bildfell B Arbogast LE Bermudez, Proc Natl Acad Sci USA 2007 104 11038 11043 10.1073/pnas.0610746104 17578930
36. The glycan-rich outer layer of the cell wall of Mycobacterium tuberculosis acts as an antiphagocytic capsule limiting the association of the bacterium with macrophages. RW Stokes R Jones-Norris DE Brooks J Beveridge D Doxsee LM Thorson, Infect Immun 2001 72 5676 5686 10.1128/IAI.72.10.5676-5686. 2004
37. Serine/threonine protein kinases PknF and PknG of Mycobacterium tuberculosis:characterization and localization. A Koul A Choidas AK Tyagi K Drlica Y Singh A Ullrich, Microbiol 2004 14 2307 2314