Proteomic analysis reveals a role for protein kinase C-α in phagosome maturation

Biochemical and Biophysical Research Communications

Volumn 319, Issue 3, 2004, Pages 810-816

  Ng Yan Hing, John Derek ^a   Desjardins, Michel ^b   Descoteaux, Albert ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Macrophage; Phagocytosis; Phagolysosome; Protein kinase C; Proteomics

Indexed keywords

CATHEPSIN D; CATHEPSIN S; FLOTILLIN 1; GUANOSINE TRIPHOSPHATASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; PROTEIN KINASE C ALPHA; RAB7 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MATURATION; CONTROLLED STUDY; DOWN REGULATION; ENDOSOME; ENZYME ACTIVITY; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS;

ANIMALS; ANTIGENS, CD; BIOLOGICAL MARKERS; CATHEPSIN D; CATHEPSINS; CELL LINE; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICROSPHERES; MUTATION; PHAGOSOMES; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEOME; RAB GTP-BINDING PROTEINS;

EID: 2942568013     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.05.054     Document Type: Article

References (34)

1. Aderem A., Underhill D.M. Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol. 17:1999;593-623
2. Desjardins M., Huber L.A., Parton R.G., Griffiths G. Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J. Cell Biol. 124:1994;677-688
3. Jahraus A., Storrie B., Griffiths G., Desjardins M. Evidence for retrograde traffic between terminal lysosomes and the prelysosomal/late endosome compartment. J. Cell Sci. 107:1994;145-157
4. Mayorga L.S., Bertini F., Stahl P.D. Fusion of newly formed phagosomes with endosomes in intact cells and in a cell-free system. J. Biol. Chem. 266:1991;6511-6517
5. Alvarez-Dominguez C., Barbieri A.M., Beron W., Wandinger-Ness A., Stahl P.D. Phagocytosed live Listeria monocytogenes influences Rab5-regulated in vitro phagosome-endosome fusion. J. Biol. Chem. 271:1996;13834-13843
6. Rabinowitz S., Horstmann H., Gordon S., Griffiths G. Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages. J. Cell Biol. 116:1992;95-112
7. Vieira O.V., Botelho R.J., Grinstein S. Phagosome maturation: aging gracefully. Biochem. J. 366:2002;689-704
8. Jaken S. Protein kinase C isozymes and substrates. Curr. Opin. Cell Biol. 8:1996;168-173
9. Ohno S., Nishizuka Y. Protein kinase C isotypes and their specific functions: prologue. J. Biochem. (Tokyo). 132:2002;509-511
10. Breton A., Descoteaux A. Protein kinase C-α participates in FcgammaR-mediated phagocytosis in macrophages. Biochem. Biophys. Res. Commun. 276:2000;472-476
11. Brumell J.H., Howard J.C., Craig K., Grinstein S., Schreiber A.D., Tyers M. Expression of the protein kinase C substrate pleckstrin in macrophages: association with phagosomal membranes. J. Immunol. 163:1999;3388-3395
12. Allen L.A., Allgood J.A. Atypical protein kinase C-ζ is essential for delayed phagocytosis of Helicobacter pylori. Curr. Biol. 12:2002;1762-1766
13. Larsen E.C., DiGennaro J.A., Saito N., Mehta S., Loegering D.J., Mazurkiewicz J.E., Lennartz M.R. Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells. J. Immunol. 165:2000;2809-2817
14. Larsen E.C., Ueyama T., Brannock P.M., Shirai Y., Saito N., Larsson C., Loegering D., Weber P.B., Lennartz M.R. A role for PKC-varepsilon in FcgammaR-mediated phagocytosis by RAW 264.7 cells. J. Cell Biol. 159:2002;939-944
15. Zheng L., Zomerdijk T.P., Aarnoudse C., van Furth R., Nibbering P.H. Role of protein kinase C isozymes in Fc gamma receptor-mediated intracellular killing of Staphylococcus aureus by human monocytes. J. Immunol. 155:1995;776-784
16. Zheleznyak A., Brown E.J. Immunoglobulin-mediated phagocytosis by human monocytes requires protein kinase C activation. Evidence for protein kinase C translocation to phagosomes. J. Biol. Chem. 267:1992;12042-12048
17. Allen L.H., Aderem A. A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages. J. Exp. Med. 182:1995;829-840
18. Itoh S., Suzuki K., Nishihata J., Iwasa M., Oku T., Nakajin S., Nauseef W.M., Toyoshima S. The role of protein kinase C in the transient association of p57, a coronin family actin-binding protein, with phagosomes. Biol. Pharm. Bull. 25:2002;837-844
19. Garin J., Diez R., Kieffer S., Dermine J.F., Duclos S., Gagnon E., Sadoul R., Rondeau C., Desjardins M. The phagosome proteome. Insight into phagosome functions. J. Cell Biol. 152:2001;165-180
20. St-Denis A., Chano F., Tremblay P., St-Pierre Y., Descoteaux A. Protein kinase C-α modulates lipopolysaccharide-induced functions in a murine macrophage cell line. J. Biol. Chem. 273:1998;32787-32792
21. Desjardins M., Celis J.E., van Meer G., Dieplinger H., Jahraus A., Griffiths G., Huber L.A. Molecular characterization of phagosomes. J. Biol. Chem. 269:1994;32194-32200
22. Desjardins M. Biogenesis of phagolysosomes: the kiss and run hypothesis. Trends Cell Biol. 5:1995;183-186
23. Desjardins M., Griffiths G. Phagocytosis: latex leads the way. Curr. Opin. Cell Biol. 15:2003;498-503
24. Dermine J.F., Duclos S., Garin J., St-Louis F., Rea S., Parton R.G., Desjardins M. Flotillin-1-enriched lipid raft domains accumulate on maturing phagosomes. J. Biol. Chem. 276:2001;18507-18512
25. Feng Y., Press B., Wandinger-Ness A. Rab 7: an important regulator of late endocytic membrane traffic. J. Cell Biol. 131:1995;1435-1452
26. Vitelli R., Santillo M., Lattero D., Chiariello M., Bifulco M., Bruni C.B., Bucci C. Role of the small GTPase Rab7 in the late endocytic pathway. J. Biol. Chem. 272:1997;4391-4397
27. Bucci C., Thomsen P., Nicoziani P., McCarthy J., van Deurs B. Rab7: a key to lysosome biogenesis. Mol. Biol. Cell. 11:2000;467-480
28. Rupper A., Grove B., Cardelli J. Rab7 regulates phagosome maturation in Dictyostelium. J. Cell Sci. 114:2001;2449-2460
29. Fitzgerald M.L., Reed G.L. Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distribution. Biochem. J. 342(Pt. 2):1999;353-360
30. Holm A., Tejle K., Gunnarsson T., Magnusson K.E., Descoteaux A., Rasmusson B. Role of protein kinase Cα for uptake of unopsonized prey and phagosomal maturation in macrophages. Biochem. Biophys. Res. Commun. 302:2003;653-658
31. Villadangos J.A., Ploegh H.L. Proteolysis in MHC class II antigen presentation: who's in charge? Immunity. 12:2000;233-239
32. Honey K., Rudensky A.Y. Lysosomal cysteine proteases regulate antigen presentation. Nat. Rev. Immunol. 3:2003;472-482
33. Scianimanico S., Desrosiers M., Dermine J.-F., Méresse S., Descoteaux A., Desjardins M. Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes. Cell. Microbiol. 1:1999;19-32
34. Holm Å., Tejle K., Magnusson K.E., Descoteaux A., Rasmusson B. Leishmania donovani lipophosphoglycan causes periphagosomal actin accumulation: correlation with impaired translocation of PKCα and defective phagosome maturation. Cell. Microbiol. 3:2001;439-447