Protein kinase C-α participates in FcγR-mediated phagocytosis in macrophages

Biochemical and Biophysical Research Communications

Volumn 276, Issue 2, 2000, Pages 472-476

  Breton, Anouk ^a   Descoteaux, Albert ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

ERK1 2; Fc receptor; Macrophage; Phagocytosis; Protein kinase C; Signal transduction

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ADHESION; ENZYME ACTIVATION; GENE OVEREXPRESSION; MACROPHAGE; MOUSE; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 0034710805     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3511     Document Type: Article

References (33)

1. Mechanisms of phagocytosis in macrophages
2. Tyrosine phosphorylation of the gamma subunit of Fc gamma receptors, p72syk, and paxillin during Fc receptor-mediated phagocytosis in macrophages
3. Clustered syk tyrosine kinase domains trigger phagocytosis
4. Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly
5. A critical role for syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages
6. The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils
7. Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling
8. A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages
9. Requirements for both Racl and Cdc42 in membrane ruffling and phagocytosis in leukocytes
10. Rho is required for the initiation of calcium signaling and phagocytosis by Fcgamma receptors in macrophages
11. Fc gamma receptor cross-linking activates p42, p38, and JNK/SAPK mitogen-activated protein kinases in murine macrophages: Role for p42MAPK in Fc gamma receptor-stimulated TNF-alpha synthesis
12. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
13. A requirement for ARF6 in Fcgamma receptor-mediated phagocytosis in macrophages
14. A requirement for phosphatidylinositol 3-kinase in pseudopod extension
15. Differential requirements for cellular cytoskeleton in human macrophage complement receptor- and Fc receptor-mediated phagocytosis
16. Immunoglobulin-mediated phagocytosis by human monocytes requires protein kinase C activation. Evidence for protein kinase C translocation to phagosomes
17. Protein kinase C activation precedes arachidonic acid release during IgG-mediated phagocytosis
18. Role of protein kinase C isozymes in Fc gamma receptor-mediated intracellular killing of Staphylococcus aureus by human monocytes
19. Molecular definition of distinct cytoskeletal structures involved in complement- and Fc receptor-mediated phagocytosis in macrophages
20. A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages
21. A role for PKC-α in the control of infection by intracellular pathogens in macrophages
22. Protein kinase C-α modulates lipopolysaccharide-induced functions in a murine macrophage cell line
23. Differences in the mode of phagocytosis with Fc and C3 receptors in macrophages
24. Mitogen-activated protein kinase is activated during IgG-mediated phagocytosis, but is not required for target ingestion
25. MacMARCKS is not essential for phagocytosis in macrophages
26. Isolation and characterization of monoclonal antibodies directed against novel components of macrophage phagosomes
27. Dynamin 2 Is required for phagocytosis in macrophages
28. Amphiphysin IIm, a novel amphiphysin II isoform, is required for macrophage phagocytosis
29. Amphiphysin heterodimers: Potential role in clathrin-mediated endocytosis
30. Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals
31. Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO
32. Regulation of ARNO nucleotide exchange by a PH domain electrostatic switch
33. Fcgamma receptor-mediated mitogen-activated protein kinase activation in monocytes is independent of Ras