메뉴 건너뛰기




Volumn 103, Issue 2, 2010, Pages 761-778

Global gene expression analysis of rodent motor neurons following spinal cord injury associates molecular mechanisms with development of postinjury spasticity

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; CALCIUM CHANNEL; CHLORIDE CHANNEL; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER RECEPTOR; POTASSIUM CHANNEL; RNA; SODIUM CHANNEL;

EID: 76649091920     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00609.2009     Document Type: Article
Times cited : (41)

References (112)
  • 1
    • 0141646451 scopus 로고    scopus 로고
    • Metabotropic modulation of motoneurons by scratch-like spinal network activity
    • Alaburda A, Hounsgaard J. Metabotropic modulation of motoneurons by scratch-like spinal network activity. J Neurosci 23: 8625-8629, 2003.
    • (2003) J Neurosci , vol.23 , pp. 8625-8629
    • Alaburda, A.1    Hounsgaard, J.2
  • 3
    • 33847667598 scopus 로고    scopus 로고
    • Expression of L-type calcium channel alpha(1)-1.2 and alpha(1)-1.3 subunits on rat sacral motoneurons following chronic spinal cord injury
    • Anelli R, Sanelli L, Bennett DJ, Heckman CJ. Expression of L-type calcium channel alpha(1)-1.2 and alpha(1)-1.3 subunits on rat sacral motoneurons following chronic spinal cord injury. Neuroscience 145: 751-763, 2007.
    • (2007) Neuroscience , vol.145 , pp. 751-763
    • Anelli, R.1    Sanelli, L.2    Bennett, D.J.3    Heckman, C.J.4
  • 4
    • 0038045158 scopus 로고    scopus 로고
    • Auxiliary subunits: Essential components of the voltage-gated calcium channel complex
    • Arikkath J, Campbell KP. Auxiliary subunits: essential components of the voltage-gated calcium channel complex. Curr Opin Neurobiol 13: 298-307, 2003.
    • (2003) Curr Opin Neurobiol , vol.13 , pp. 298-307
    • Arikkath, J.1    Campbell, K.P.2
  • 5
    • 0034948896 scopus 로고    scopus 로고
    • A Bayesian framework for the analysis of microarray expression data: Regularized t-test and statistical inferences of gene changes
    • Baldi P, Long AD. A Bayesian framework for the analysis of microarray expression data: regularized t-test and statistical inferences of gene changes. Bioinformatics 17: 509-519, 2001.
    • (2001) Bioinformatics , vol.17 , pp. 509-519
    • Baldi, P.1    Long, A.D.2
  • 6
    • 0019508603 scopus 로고
    • Denervation supersensitivity to 5-hydroxytryptophan in rats following spinal transection and 5,7-dihydroxytryptamine injection
    • Barbeau H, Bedard P. Denervation supersensitivity to 5-hydroxytryptophan in rats following spinal transection and 5,7-dihydroxytryptamine injection. Neuropharmacology 20: 611-616, 1981.
    • (1981) Neuropharmacology , vol.20 , pp. 611-616
    • Barbeau, H.1    Bedard, P.2
  • 11
    • 42449087363 scopus 로고    scopus 로고
    • 2+ channel signaling complexes in neurons
    • 2+ channel signaling complexes in neurons. J Neurochem 105: 573-583, 2008.
    • (2008) J Neurochem , vol.105 , pp. 573-583
    • Calin-Jageman, I.1    Lee, A.2
  • 12
    • 0035378383 scopus 로고    scopus 로고
    • + channels: An unexpected form of cellular plasticity
    • + channels: an unexpected form of cellular plasticity. Nat Rev Neurosci 2: 397-407, 2001.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 397-407
    • Cantrell, A.R.1    Catterall, W.A.2
  • 13
    • 0242472014 scopus 로고    scopus 로고
    • Dendritic L-type calcium currents in mouse spinal motoneurons: Implications for bistability
    • Carlin KP, Jones KE, Jiang Z, Jordan LM, Brownstone RM. Dendritic L-type calcium currents in mouse spinal motoneurons: implications for bistability. Eur J Neurosci 12: 1635-1646, 2000.
    • (2000) Eur J Neurosci , vol.12 , pp. 1635-1646
    • Carlin, K.P.1    Jones, K.E.2    Jiang, Z.3    Jordan, L.M.4    Brownstone, R.M.5
  • 14
    • 29844438166 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltagegated sodium channels
    • Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltagegated sodium channels. Pharmacol Rev 57: 397-409, 2005a.
    • (2005) Pharmacol Rev , vol.57 , pp. 397-409
    • Catterall, W.A.1    Goldin, A.L.2    Waxman, S.G.3
  • 15
    • 29844439240 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels
    • Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol Rev 57: 411-425, 2005b.
    • (2005) Pharmacol Rev , vol.57 , pp. 411-425
    • Catterall, W.A.1    Perez-Reyes, E.2    Snutch, T.P.3    Striessnig, J.4
  • 17
    • 33845788244 scopus 로고    scopus 로고
    • A receptor associated proteins: A key factor regulating GABAA receptor function
    • A receptor associated proteins: a key factor regulating GABAA receptor function. J Neurochem 100: 279-294, 2007.
    • (2007) J Neurochem , vol.100 , pp. 279-294
    • Chen, Z.W.1    Olsen, R.W.2
  • 19
    • 0023789986 scopus 로고
    • Plateau potentials in alpha-motoneurones induced by intravenous injection of L-dopa and clonidine in the spinal cat
    • Conway BA, Hultborn H, Kiehn O, Mintz I. Plateau potentials in alpha-motoneurones induced by intravenous injection of L-dopa and clonidine in the spinal cat. J Physiol 405: 369-384, 1988.
    • (1988) J Physiol , vol.405 , pp. 369-384
    • Conway, B.A.1    Hultborn, H.2    Kiehn, O.3    Mintz, I.4
  • 20
    • 0023730011 scopus 로고
    • Maintained changes in motoneuronal excitability by short-lasting synaptic inputs in the decerebrate cat
    • Crone C, Hultborn H, Kiehn O, Mazieres L, Wigstrom H. Maintained changes in motoneuronal excitability by short-lasting synaptic inputs in the decerebrate cat. J Physiol 405: 321-343, 1988.
    • (1988) J Physiol , vol.405 , pp. 321-343
    • Crone, C.1    Hultborn, H.2    Kiehn, O.3    Mazieres, L.4    Wigstrom, H.5
  • 21
    • 33645797362 scopus 로고    scopus 로고
    • Divergence between motoneurons: Gene expression profiling provides a molecular characterization of functionally discrete somatic and autonomic motoneurons
    • Cui D, Dougherty KJ, Machacek DW, Sawchuk M, Hochman S, Baro DJ. Divergence between motoneurons: gene expression profiling provides a molecular characterization of functionally discrete somatic and autonomic motoneurons. Physiol Genomics 24: 276-289, 2006.
    • (2006) Physiol Genomics , vol.24 , pp. 276-289
    • Cui, D.1    Dougherty, K.J.2    Machacek, D.W.3    Sawchuk, M.4    Hochman, S.5    Baro, D.J.6
  • 24
    • 67649973701 scopus 로고    scopus 로고
    • Supramolecular assemblies and localized regulation of voltage-gated ion channels
    • Dai S, Hall DD, Hell JW. Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol Rev 89: 411-452, 2009.
    • (2009) Physiol Rev , vol.89 , pp. 411-452
    • Dai, S.1    Hall, D.D.2    Hell, J.W.3
  • 25
    • 1842408933 scopus 로고    scopus 로고
    • Metabotropic synaptic regulation of intrinsic response properties of turtle spinal motoneurones
    • Delgado-Lezama R, Perrier JF, Nedergaard S, Svirskis G, Hounsgaard J. Metabotropic synaptic regulation of intrinsic response properties of turtle spinal motoneurones. J Physiol 504: 97-102, 1997.
    • (1997) J Physiol , vol.504 , pp. 97-102
    • Delgado-Lezama, R.1    Perrier, J.F.2    Nedergaard, S.3    Svirskis, G.4    Hounsgaard, J.5
  • 26
    • 3242743582 scopus 로고    scopus 로고
    • Burns AS. Spinal shock revisited: A four-phase model
    • Ditunno JF, Little JW, Tessler A, Burns AS. Spinal shock revisited: a four-phase model. Spinal Cord 42: 383-395, 2004.
    • (2004) Spinal Cord , vol.42 , pp. 383-395
    • Ditunno, J.F.1    Little, J.W.2    Tessler, A.3
  • 27
    • 0345185172 scopus 로고    scopus 로고
    • Beta subunits of voltage-gated calcium channels
    • Dolphin AC. Beta subunits of voltage-gated calcium channels. J Bioenerg Biomembr 35: 599-620, 2003.
    • (2003) J Bioenerg Biomembr , vol.35 , pp. 599-620
    • Dolphin, A.C.1
  • 28
    • 0024943082 scopus 로고
    • Possible functions of transmitter-controlled plateau potentials in alpha motoneurones
    • Eken T, Hultborn H, Kiehn O. Possible functions of transmitter-controlled plateau potentials in alpha motoneurones. Prog Brain Res 80: 239-242, 257-267, 1989.
    • (1989) Prog Brain Res , vol.80 , Issue.239-242 , pp. 257-267
    • Eken, T.1    Hultborn, H.2    Kiehn, O.3
  • 29
    • 3042668916 scopus 로고    scopus 로고
    • Neuregulins and the neuromuscular system: 10 years of answers and questions
    • Falls DL. Neuregulins and the neuromuscular system: 10 years of answers and questions. J Neurocytol 32: 619-647, 2003.
    • (2003) J Neurocytol , vol.32 , pp. 619-647
    • Falls, D.L.1
  • 30
    • 33745614665 scopus 로고    scopus 로고
    • 2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand
    • 2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand. J Neurosci 26: 6259-6268, 2006.
    • (2006) J Neurosci , vol.26 , pp. 6259-6268
    • Gao, L.1    Blair, L.A.2    Salinas, G.D.3    Needleman, L.A.4    Marshall, J.5
  • 31
    • 0037066061 scopus 로고    scopus 로고
    • Glycine and GABA(A) receptor subunits on Renshaw cells: Relationship with presynaptic neurotransmitters and postsynaptic gephyrin clusters
    • Geiman EJ, Zheng W, Fritschy JM, Alvarez FJ. Glycine and GABA(A) receptor subunits on Renshaw cells: relationship with presynaptic neurotransmitters and postsynaptic gephyrin clusters. J Comp Neurol 444: 275-289, 2002.
    • (2002) J Comp Neurol , vol.444 , pp. 275-289
    • Geiman, E.J.1    Zheng, W.2    Fritschy, J.M.3    Alvarez, F.J.4
  • 32
    • 0033548721 scopus 로고    scopus 로고
    • Autoradiographic study of alpha1- and alpha2-noradrenergic and serotonin1A receptors in the spinal cord of normal and chronically transected cats
    • Giroux N, Rossignol S, Reader TA. Autoradiographic study of alpha1- and alpha2-noradrenergic and serotonin1A receptors in the spinal cord of normal and chronically transected cats. J Comp Neurol 406: 402-414, 1999.
    • (1999) J Comp Neurol , vol.406 , pp. 402-414
    • Giroux, N.1    Rossignol, S.2    Reader, T.A.3
  • 33
    • 61349121391 scopus 로고    scopus 로고
    • NKCC1 and AE3 appear to accumulate chloride in embryonic motoneurons
    • Gonzalez-Islas C, Chub N, Wenner P. NKCC1 and AE3 appear to accumulate chloride in embryonic motoneurons. J Neurophysiol 101: 507-518, 2009.
    • (2009) J Neurophysiol , vol.101 , pp. 507-518
    • Gonzalez-Islas, C.1    Chub, N.2    Wenner, P.3
  • 34
    • 26244434881 scopus 로고    scopus 로고
    • User-defined variables that affect outcome in spinal cord contusion/compression models
    • Grill RJ. User-defined variables that affect outcome in spinal cord contusion/compression models. Exp Neurol 196: 1-5, 2005.
    • (2005) Exp Neurol , vol.196 , pp. 1-5
    • Grill, R.J.1
  • 36
    • 33747110336 scopus 로고    scopus 로고
    • Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro
    • Gunther S, Maroteaux L, Schwarzacher SW. Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro. J Neurobiol 66: 949-961, 2006.
    • (2006) J Neurobiol , vol.66 , pp. 949-961
    • Gunther, S.1    Maroteaux, L.2    Schwarzacher, S.W.3
  • 37
    • 0021716508 scopus 로고
    • Spinal cord serotonin: A biochemical and immunohistochemical study following transection
    • Hadjiconstantinou M, Panula P, Lackovic Z, Neff NH. Spinal cord serotonin: a biochemical and immunohistochemical study following transection. Brain Res 322: 245-254, 1984.
    • (1984) Brain Res , vol.322 , pp. 245-254
    • Hadjiconstantinou, M.1    Panula, P.2    Lackovic, Z.3    Neff, N.H.4
  • 39
    • 36849070907 scopus 로고    scopus 로고
    • Dopaminergic modulation of spinal neuronal excitability
    • Han P, Nakanishi ST, Tran MA, Whelan PJ. Dopaminergic modulation of spinal neuronal excitability. J Neurosci 27: 13192-13204, 2007.
    • (2007) J Neurosci , vol.27 , pp. 13192-13204
    • Han, P.1    Nakanishi, S.T.2    Tran, M.A.3    Whelan, P.J.4
  • 41
    • 33748523450 scopus 로고    scopus 로고
    • 5-HT2 receptor activation facilitates a persistent sodium current and repetitive firing in spinal motoneurons of rats with and without chronic spinal cord injury
    • Harvey PJ, Li X, Li Y, Bennett DJ. 5-HT2 receptor activation facilitates a persistent sodium current and repetitive firing in spinal motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 96: 1158-1170, 2006a.
    • (2006) J Neurophysiol , vol.96 , pp. 1158-1170
    • Harvey, P.J.1    Li, X.2    Li, Y.3    Bennett, D.J.4
  • 42
    • 33748529605 scopus 로고    scopus 로고
    • Endogenous monoamine receptor activation is essential for enabling persistent sodium currents and repetitive firing in rat spinal motoneurons
    • Harvey PJ, Li X, Li Y, Bennett DJ. Endogenous monoamine receptor activation is essential for enabling persistent sodium currents and repetitive firing in rat spinal motoneurons. J Neurophysiol 96: 1171-1186, 2006b.
    • (2006) J Neurophysiol , vol.96 , pp. 1171-1186
    • Harvey, P.J.1    Li, X.2    Li, Y.3    Bennett, D.J.4
  • 43
    • 33748580668 scopus 로고    scopus 로고
    • Persistent sodium currents and repetitive firing in motoneurons of the sacrocaudal spinal cord of adult rats
    • Harvey PJ, Li Y, Li X, Bennett DJ. Persistent sodium currents and repetitive firing in motoneurons of the sacrocaudal spinal cord of adult rats. J Neurophysiol 96: 1141-1157, 2006c.
    • (2006) J Neurophysiol , vol.96 , pp. 1141-1157
    • Harvey, P.J.1    Li, Y.2    Li, X.3    Bennett, D.J.4
  • 44
    • 13244298118 scopus 로고    scopus 로고
    • Persistent inward currents in motoneuron dendrites: Implications for motor output
    • Heckman CJ, Gorassini MA, Bennett DJ. Persistent inward currents in motoneuron dendrites: implications for motor output. Muscle Nerve 31: 135-156, 2005.
    • (2005) Muscle Nerve , vol.31 , pp. 135-156
    • Heckman, C.J.1    Gorassini, M.A.2    Bennett, D.J.3
  • 45
    • 0042568798 scopus 로고    scopus 로고
    • Neuronal calcium sensor-1: A multifunctional regulator of secretion
    • Hilfiker S. Neuronal calcium sensor-1: a multifunctional regulator of secretion. Biochem Soc Trans 31: 828-832, 2003.
    • (2003) Biochem Soc Trans , vol.31 , pp. 828-832
    • Hilfiker, S.1
  • 46
    • 7044272142 scopus 로고    scopus 로고
    • Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones
    • Holohean AM, Hackman JC. Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones. Br J Pharmacol 143: 351-360, 2004.
    • (2004) Br J Pharmacol , vol.143 , pp. 351-360
    • Holohean, A.M.1    Hackman, J.C.2
  • 47
    • 0023780272 scopus 로고
    • Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan
    • Hounsgaard J, Hultborn H, Jespersen B, Kiehn O. Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan. J Physiol 405: 345-367, 1988.
    • (1988) J Physiol , vol.405 , pp. 345-367
    • Hounsgaard, J.1    Hultborn, H.2    Jespersen, B.3    Kiehn, O.4
  • 48
    • 0024319735 scopus 로고
    • Serotonin-induced bistability of turtle motoneurones caused by a nifedipine-sensitive calcium plateau potential
    • Hounsgaard J, Kiehn O. Serotonin-induced bistability of turtle motoneurones caused by a nifedipine-sensitive calcium plateau potential. J Physiol 414: 265-282, 1989.
    • (1989) J Physiol , vol.414 , pp. 265-282
    • Hounsgaard, J.1    Kiehn, O.2
  • 49
    • 33846039019 scopus 로고    scopus 로고
    • Hubbard TJ, Aken BL, Beal K, Ballester B, Caccamo M, Chen Y, Clarke L, Coates G, Cunningham F, Cutts T, Down T, Dyer SC, Fitzgerald S, Fernandez-Banet J, Graf S, Haider S, Hammond M, Herrero J, Holland R, Howe K, Johnson N, Kahari A, Keefe D, Kokocinski F, Kulesha E, Lawson D, Longden I, Melsopp C, Megy K, Meidl P, Ouverdin B, Parker A, Prlic A, Rice S, Rios D, Schuster M, Sealy I, Severin J, Slater G, Smedley D, Spudich G, Trevanion S, Vilella A, Vogel J, White S, Wood M, Cox T, Curwen V, Durbin R, Fernandez-Suarez XM, Flicek P, Kasprzyk A, Proctor G, Searle S, Smith J, Ureta-Vidal A, Birney E. Ensembl 2007. Nucleic Acids Res 35: D610-D617, 2007.
    • Hubbard TJ, Aken BL, Beal K, Ballester B, Caccamo M, Chen Y, Clarke L, Coates G, Cunningham F, Cutts T, Down T, Dyer SC, Fitzgerald S, Fernandez-Banet J, Graf S, Haider S, Hammond M, Herrero J, Holland R, Howe K, Johnson N, Kahari A, Keefe D, Kokocinski F, Kulesha E, Lawson D, Longden I, Melsopp C, Megy K, Meidl P, Ouverdin B, Parker A, Prlic A, Rice S, Rios D, Schuster M, Sealy I, Severin J, Slater G, Smedley D, Spudich G, Trevanion S, Vilella A, Vogel J, White S, Wood M, Cox T, Curwen V, Durbin R, Fernandez-Suarez XM, Flicek P, Kasprzyk A, Proctor G, Searle S, Smith J, Ureta-Vidal A, Birney E. Ensembl 2007. Nucleic Acids Res 35: D610-D617, 2007.
  • 50
    • 0033399914 scopus 로고    scopus 로고
    • Plateau potentials and their role in regulating motoneuronal firing
    • Hultborn H. Plateau potentials and their role in regulating motoneuronal firing. Prog Brain Res 123: 39-48, 1999.
    • (1999) Prog Brain Res , vol.123 , pp. 39-48
    • Hultborn, H.1
  • 51
    • 0038644183 scopus 로고    scopus 로고
    • Changes in neuronal properties and spinal reflexes during development of spasticity following spinal cord lesions and stroke: Studies in animal models and patients
    • Hultborn H. Changes in neuronal properties and spinal reflexes during development of spasticity following spinal cord lesions and stroke: studies in animal models and patients. J Rehabil Med 35, Suppl. 41: 46-55, 2003.
    • (2003) J Rehabil Med , vol.35 , Issue.SUPPL. 41 , pp. 46-55
    • Hultborn, H.1
  • 52
    • 0027021104 scopus 로고
    • Neuromodulation of vertebrate motor neuron membrane properties
    • Hultborn H, Kiehn O. Neuromodulation of vertebrate motor neuron membrane properties. Curr Opin Neurobiol 2: 770-775, 1992.
    • (1992) Curr Opin Neurobiol , vol.2 , pp. 770-775
    • Hultborn, H.1    Kiehn, O.2
  • 54
    • 0028980448 scopus 로고
    • Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line
    • Isom LL, Scheuer T, Brownstein AB, Ragsdale DS, Murphy BJ, Catterall WA. Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line. J Biol Chem 270: 3306-3312, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 3306-3312
    • Isom, L.L.1    Scheuer, T.2    Brownstein, A.B.3    Ragsdale, D.S.4    Murphy, B.J.5    Catterall, W.A.6
  • 55
    • 33751200627 scopus 로고    scopus 로고
    • Inhibitory postsynaptic potentials in lumbar motoneurons remain depolarizing after neonatal spinal cord transection in the rat
    • Jean-Xavier C, Pflieger JF, Liabeuf S, Vinay L. Inhibitory postsynaptic potentials in lumbar motoneurons remain depolarizing after neonatal spinal cord transection in the rat. J Neurophysiol 96: 2274-2281, 2006.
    • (2006) J Neurophysiol , vol.96 , pp. 2274-2281
    • Jean-Xavier, C.1    Pflieger, J.F.2    Liabeuf, S.3    Vinay, L.4
  • 56
    • 67349230237 scopus 로고    scopus 로고
    • Changes in GABA(A) receptor subunit gamma 2 in extensor and flexor motoneurons and astrocytes after spinal cord transection and motor training
    • Khristy W, Ali NJ, Bravo AB, de Leon R, Roy RR, Zhong H, London NJ, Edgerton VR, Tillakaratne NJ. Changes in GABA(A) receptor subunit gamma 2 in extensor and flexor motoneurons and astrocytes after spinal cord transection and motor training. Brain Res 1273: 9-17, 2009.
    • (2009) Brain Res , vol.1273 , pp. 9-17
    • Khristy, W.1    Ali, N.J.2    Bravo, A.B.3    de Leon, R.4    Roy, R.R.5    Zhong, H.6    London, N.J.7    Edgerton, V.R.8    Tillakaratne, N.J.9
  • 57
    • 0031696274 scopus 로고    scopus 로고
    • Functional role of plateau potentials in vertebrate motor neurons
    • Kiehn O, Eken T. Functional role of plateau potentials in vertebrate motor neurons. Curr Opin Neurobiol 8: 746-752, 1998.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 746-752
    • Kiehn, O.1    Eken, T.2
  • 58
    • 0037092353 scopus 로고    scopus 로고
    • Calcium and calcium-activated currents in vagotomized rat primary vagal afferent neurons
    • Lancaster E, Oh EJ, Gover T, Weinreich D. Calcium and calcium-activated currents in vagotomized rat primary vagal afferent neurons. J Physiol 540: 543-556, 2002.
    • (2002) J Physiol , vol.540 , pp. 543-556
    • Lancaster, E.1    Oh, E.J.2    Gover, T.3    Weinreich, D.4
  • 59
    • 0033021234 scopus 로고    scopus 로고
    • Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine
    • Lee RH, Heckman CJ. Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine. J Neurophysiol 81: 2164-2174, 1999.
    • (1999) J Neurophysiol , vol.81 , pp. 2164-2174
    • Lee, R.H.1    Heckman, C.J.2
  • 60
    • 0035186745 scopus 로고    scopus 로고
    • Essential role of a fast persistent inward current in action potential initiation and control of rhythmic firing
    • Lee RH, Heckman CJ. Essential role of a fast persistent inward current in action potential initiation and control of rhythmic firing. J Neurophysiol 85: 472-475, 2001.
    • (2001) J Neurophysiol , vol.85 , pp. 472-475
    • Lee, R.H.1    Heckman, C.J.2
  • 61
    • 0025266323 scopus 로고
    • Labelling neurons with fluorescent dyes administered via intravenous, subcutaneous or intraperitoneal route
    • Leong SK, Ling EA. Labelling neurons with fluorescent dyes administered via intravenous, subcutaneous or intraperitoneal route. J Neurosci Methods 32: 15-23, 1990.
    • (1990) J Neurosci Methods , vol.32 , pp. 15-23
    • Leong, S.K.1    Ling, E.A.2
  • 62
    • 33846908702 scopus 로고    scopus 로고
    • Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury
    • Li X, Murray K, Harvey PJ, Ballou EW, Bennett DJ. Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 97: 1236-1246, 2007.
    • (2007) J Neurophysiol , vol.97 , pp. 1236-1246
    • Li, X.1    Murray, K.2    Harvey, P.J.3    Ballou, E.W.4    Bennett, D.J.5
  • 63
    • 0041816000 scopus 로고    scopus 로고
    • Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats
    • Li Y, Bennett DJ. Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats. J Neurophysiol 90: 857-869, 2003.
    • (2003) J Neurophysiol , vol.90 , pp. 857-869
    • Li, Y.1    Bennett, D.J.2
  • 64
    • 0842327877 scopus 로고    scopus 로고
    • Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats
    • Li Y, Gorassini MA, Bennett DJ. Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats. J Neurophysiol 91: 767-783, 2004a.
    • (2004) J Neurophysiol , vol.91 , pp. 767-783
    • Li, Y.1    Gorassini, M.A.2    Bennett, D.J.3
  • 65
    • 14844320586 scopus 로고    scopus 로고
    • Effects of baclofen on spinal reflexes and persistent inward currents in motoneurons of chronic spinal rats with spasticity
    • Li Y, Li X, Harvey PJ, Bennett DJ. Effects of baclofen on spinal reflexes and persistent inward currents in motoneurons of chronic spinal rats with spasticity. J Neurophysiol 92: 2694-2703, 2004b.
    • (2004) J Neurophysiol , vol.92 , pp. 2694-2703
    • Li, Y.1    Li, X.2    Harvey, P.J.3    Bennett, D.J.4
  • 66
    • 0032899990 scopus 로고    scopus 로고
    • Incomplete spinal cord injury: Neuronal mechanisms of motor recovery and hyperreflexia
    • Little JW, Ditunno JF Jr, Stiens SA, Harris RM. Incomplete spinal cord injury: neuronal mechanisms of motor recovery and hyperreflexia. Arch Phys Med Rehabil 80: 587-599, 1999.
    • (1999) Arch Phys Med Rehabil , vol.80 , pp. 587-599
    • Little, J.W.1    Ditunno Jr, J.F.2    Stiens, S.A.3    Harris, R.M.4
  • 67
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 68
    • 33745264905 scopus 로고    scopus 로고
    • Noradrenaline unmasks novel self-reinforcing motor circuits within the mammalian spinal cord
    • Machacek DW, Hochman S. Noradrenaline unmasks novel self-reinforcing motor circuits within the mammalian spinal cord. J Neurosci 26: 5920-5928, 2006.
    • (2006) J Neurosci , vol.26 , pp. 5920-5928
    • Machacek, D.W.1    Hochman, S.2
  • 69
    • 4143062672 scopus 로고    scopus 로고
    • Modulation of locomotor activity by multiple 5-HT and dopaminergic receptor subtypes in the neonatal mouse spinal cord
    • Madriaga MA, McPhee LC, Chersa T, Christie KJ, Whelan PJ. Modulation of locomotor activity by multiple 5-HT and dopaminergic receptor subtypes in the neonatal mouse spinal cord. J Neurophysiol 92: 1566-1576, 2004.
    • (2004) J Neurophysiol , vol.92 , pp. 1566-1576
    • Madriaga, M.A.1    McPhee, L.C.2    Chersa, T.3    Christie, K.J.4    Whelan, P.J.5
  • 70
    • 0242526137 scopus 로고    scopus 로고
    • Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors
    • Matsuda K, Fletcher M, Kamiya Y, Yuzaki M. Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors. J Neurosci 23: 10064-10073, 2003.
    • (2003) J Neurosci , vol.23 , pp. 10064-10073
    • Matsuda, K.1    Fletcher, M.2    Kamiya, Y.3    Yuzaki, M.4
  • 71
    • 0037063705 scopus 로고    scopus 로고
    • Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary beta 1, beta 2 and beta 3 subunits
    • Meadows LS, Chen YH, Powell AJ, Clare JJ, Ragsdale DS. Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary beta 1, beta 2 and beta 3 subunits. Neuroscience 114: 745-753, 2002.
    • (2002) Neuroscience , vol.114 , pp. 745-753
    • Meadows, L.S.1    Chen, Y.H.2    Powell, A.J.3    Clare, J.J.4    Ragsdale, D.S.5
  • 72
    • 0028982140 scopus 로고
    • Modulation of GABAA receptors by tyrosine phosphorylation
    • Moss SJ, Gorrie GH, Amato A, Smart TG. Modulation of GABAA receptors by tyrosine phosphorylation. Nature 377: 344-348, 1995.
    • (1995) Nature , vol.377 , pp. 344-348
    • Moss, S.J.1    Gorrie, G.H.2    Amato, A.3    Smart, T.G.4
  • 73
    • 76649122996 scopus 로고    scopus 로고
    • Murray KC, Nakae A, Ballou T, Vavrek R, Rank MM, Stephens M, Anelli R, Harvey PJ, Heckman CJ, Bennett DJ. Role of constitutively active 5-HT2C receptors following spinal cord injury in rats. Program No. 1229. 2008 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience. 2008, CD-ROM.
    • Murray KC, Nakae A, Ballou T, Vavrek R, Rank MM, Stephens M, Anelli R, Harvey PJ, Heckman CJ, Bennett DJ. Role of constitutively active 5-HT2C receptors following spinal cord injury in rats. Program No. 1229. 2008 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience. 2008, CD-ROM.
  • 74
    • 0024158478 scopus 로고
    • The morphology and distribution of rat serotoninergic intraspinal neurons: An immunohistochemical study
    • Newton BW, Hamill RW. The morphology and distribution of rat serotoninergic intraspinal neurons: an immunohistochemical study. Brain Res Bull 20: 349-360, 1988.
    • (1988) Brain Res Bull , vol.20 , pp. 349-360
    • Newton, B.W.1    Hamill, R.W.2
  • 75
    • 33846453529 scopus 로고    scopus 로고
    • The spinal pathophysiology of spasticity-from a basic science point of view
    • Nielsen JB, Crone C, Hultborn H. The spinal pathophysiology of spasticity-from a basic science point of view. Acta Physiol (Oxford, England) 189: 171-180, 2007.
    • (2007) Acta Physiol (Oxford, England , vol.189 , pp. 171-180
    • Nielsen, J.B.1    Crone, C.2    Hultborn, H.3
  • 76
    • 17044381722 scopus 로고    scopus 로고
    • Mammalian motor neurons corelease glutamate and acetylcholine at central synapses
    • Nishimaru H, Restrepo CE, Ryge J, Yanagawa Y, Kiehn O. Mammalian motor neurons corelease glutamate and acetylcholine at central synapses. Proc Natl Acad Sci USA 102: 5245-5249, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5245-5249
    • Nishimaru, H.1    Restrepo, C.E.2    Ryge, J.3    Yanagawa, Y.4    Kiehn, O.5
  • 78
    • 0034306016 scopus 로고    scopus 로고
    • Facilitation of plateau potentials in turtle motoneurones by a pathway dependent on calcium and calmodulin
    • Perrier JF, Mejia-Gervacio S, Hounsgaard J. Facilitation of plateau potentials in turtle motoneurones by a pathway dependent on calcium and calmodulin. J Physiol 528: 107-113, 2000.
    • (2000) J Physiol , vol.528 , pp. 107-113
    • Perrier, J.F.1    Mejia-Gervacio, S.2    Hounsgaard, J.3
  • 81
    • 61849138403 scopus 로고    scopus 로고
    • Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system (Abstract)
    • Piirsoo M, Meijer D, Timmusk T. Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system (Abstract). BMC Dev Biol 9: 10, 2009.
    • (2009) BMC Dev Biol , vol.9 , pp. 10
    • Piirsoo, M.1    Meijer, D.2    Timmusk, T.3
  • 82
    • 0033554890 scopus 로고    scopus 로고
    • Modulation of synaptic GABAA receptor function by PKA and PKC in adult hippocampal neurons
    • Poisbeau P, Cheney MC, Browning MD, Mody I. Modulation of synaptic GABAA receptor function by PKA and PKC in adult hippocampal neurons. J Neurosci 19: 674-683, 1999.
    • (1999) J Neurosci , vol.19 , pp. 674-683
    • Poisbeau, P.1    Cheney, M.C.2    Browning, M.D.3    Mody, I.4
  • 84
    • 0014531780 scopus 로고
    • Neuronal plasticity in the septal nuclei of the adult rat
    • Raisman G. Neuronal plasticity in the septal nuclei of the adult rat. Brain Res 14: 25-48, 1969.
    • (1969) Brain Res , vol.14 , pp. 25-48
    • Raisman, G.1
  • 85
    • 34447307966 scopus 로고    scopus 로고
    • Role of endogenous release of norepinephrine in muscle spasms after chronic spinal cord injury
    • Rank MM, Li X, Bennett DJ, Gorassini MA. Role of endogenous release of norepinephrine in muscle spasms after chronic spinal cord injury. J Neurophysiol 97: 3166-3180, 2007.
    • (2007) J Neurophysiol , vol.97 , pp. 3166-3180
    • Rank, M.M.1    Li, X.2    Bennett, D.J.3    Gorassini, M.A.4
  • 86
    • 76649128265 scopus 로고    scopus 로고
    • Rank MM, Vavrek R, Murray K, Sanelli L, Fouad K, Gorassini M, Bennett DJ. Peripheral norepinephrine crosses the blood brain barrier and contributes to spasms after spinal cord injury. Program No. 76.9/NN17. 2008 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience. 2008, CD-ROM.
    • Rank MM, Vavrek R, Murray K, Sanelli L, Fouad K, Gorassini M, Bennett DJ. Peripheral norepinephrine crosses the blood brain barrier and contributes to spasms after spinal cord injury. Program No. 76.9/NN17. 2008 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience. 2008, CD-ROM.
  • 88
    • 56749131239 scopus 로고    scopus 로고
    • GRINL1A colocalizes with N-methyl D-aspartate receptor NR1 subunit and reduces N-methyl D-aspartate toxicity
    • Roginski RS, Goubaeva F, Mikami M, Fried-Cassorla E, Nair MR, Yang J. GRINL1A colocalizes with N-methyl D-aspartate receptor NR1 subunit and reduces N-methyl D-aspartate toxicity. Neuroreport 19: 1721-1726, 2008.
    • (2008) Neuroreport , vol.19 , pp. 1721-1726
    • Roginski, R.S.1    Goubaeva, F.2    Mikami, M.3    Fried-Cassorla, E.4    Nair, M.R.5    Yang, J.6
  • 89
    • 54849426209 scopus 로고    scopus 로고
    • Gene expression profiling of two distinct neuronal populations in the rodent spinal cord
    • Ryge J, Westerdahl AC, Alstrom P, Kiehn O. Gene expression profiling of two distinct neuronal populations in the rodent spinal cord. PLoS ONE 3: e3415, 2008.
    • (2008) PLoS ONE , vol.3
    • Ryge, J.1    Westerdahl, A.C.2    Alstrom, P.3    Kiehn, O.4
  • 90
    • 1842731881 scopus 로고    scopus 로고
    • Src kinases: A hub for NMDA receptor regulation
    • Salter MW, Kalia LV. Src kinases: a hub for NMDA receptor regulation. Nat Rev Neurosci 5: 317-328, 2004.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 317-328
    • Salter, M.W.1    Kalia, L.V.2
  • 91
    • 0028354443 scopus 로고
    • Calcium-dependent chloride current induced by axotomy in rat sympathetic neurons
    • Sanchez-Vives MV, Gallego R. Calcium-dependent chloride current induced by axotomy in rat sympathetic neurons. J Physiol 475: 391-400, 1994.
    • (1994) J Physiol , vol.475 , pp. 391-400
    • Sanchez-Vives, M.V.1    Gallego, R.2
  • 94
    • 0017340465 scopus 로고
    • A persistent negative resistance in cat lumbar motoneurons
    • Schwindt PC, Crill WE. A persistent negative resistance in cat lumbar motoneurons. Brain Res 120: 173-178, 1977.
    • (1977) Brain Res , vol.120 , pp. 173-178
    • Schwindt, P.C.1    Crill, W.E.2
  • 95
    • 0018869558 scopus 로고
    • Properties of a persistent inward current in normal and TEA-injected motoneurons
    • Schwindt PC, Crill WE. Properties of a persistent inward current in normal and TEA-injected motoneurons. J Neurophysiol 43: 1700-1724, 1980.
    • (1980) J Neurophysiol , vol.43 , pp. 1700-1724
    • Schwindt, P.C.1    Crill, W.E.2
  • 96
    • 0036673411 scopus 로고    scopus 로고
    • Subunit composition, distribution and function of GABA(A) receptor subtypes
    • Sieghart W, Sperk G. Subunit composition, distribution and function of GABA(A) receptor subtypes. Curr Topics Med Chem 2: 795-816, 2002.
    • (2002) Curr Topics Med Chem , vol.2 , pp. 795-816
    • Sieghart, W.1    Sperk, G.2
  • 97
    • 0041853532 scopus 로고    scopus 로고
    • 2+ channels responsible for plateau potentials in motoneurons from the lumbar spinal cord of the turtle
    • 2+ channels responsible for plateau potentials in motoneurons from the lumbar spinal cord of the turtle. Eur J Neurosci 18: 258-266, 2003.
    • (2003) Eur J Neurosci , vol.18 , pp. 258-266
    • Simon, M.1    Perrier, J.F.2    Hounsgaard, J.3
  • 98
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
    • Article
    • Smyth GK. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. In: Statistical Applications in Genetics and Molecular Biology [Electronic resource]. 3: Article 3, 2004.
    • (2004) Statistical Applications in Genetics and Molecular Biology [Electronic resource] , vol.3 , pp. 3
    • Smyth, G.K.1
  • 99
    • 73049161475 scopus 로고
    • Effects of partial denervation on spinal neurones and their possible relation to parkinsonism
    • Stavraky GW. Effects of partial denervation on spinal neurones and their possible relation to parkinsonism. Rev Can Biol 20: 159-166, 1961.
    • (1961) Rev Can Biol , vol.20 , pp. 159-166
    • Stavraky, G.W.1
  • 100
    • 0031892533 scopus 로고    scopus 로고
    • Transmitter regulation of plateau properties in turtle motoneurons
    • Svirskis G, Hounsgaard J. Transmitter regulation of plateau properties in turtle motoneurons. J Neurophysiol 79: 45-50, 1998.
    • (1998) J Neurophysiol , vol.79 , pp. 45-50
    • Svirskis, G.1    Hounsgaard, J.2
  • 102
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 103
    • 25444498065 scopus 로고    scopus 로고
    • Sodium channel inactivation: Molecular determinants and modulation
    • Ulbricht W. Sodium channel inactivation: molecular determinants and modulation. Physiol Rev 85: 1271-1301, 2005.
    • (2005) Physiol Rev , vol.85 , pp. 1271-1301
    • Ulbricht, W.1
  • 104
    • 76649122684 scopus 로고    scopus 로고
    • Venugopal S, Crook S, Hamm TM, Jung R. A computational study of the interaction between persistent inward currents and the recurrent inhibition of alpha motoneurons before and after injury. Program No. 1317. 2009 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience. 2009, CD-ROM.
    • Venugopal S, Crook S, Hamm TM, Jung R. A computational study of the interaction between persistent inward currents and the recurrent inhibition of alpha motoneurons before and after injury. Program No. 1317. 2009 Abstract Viewer and Itinerary Planner. Washington, DC: Society for Neuroscience. 2009, CD-ROM.
  • 106
    • 36749070905 scopus 로고    scopus 로고
    • Plasticity of spinal cord locomotor networks and contribution of cation-chloride cotransporters
    • Vinay L, Jean-Xavier C. Plasticity of spinal cord locomotor networks and contribution of cation-chloride cotransporters. Brain Res Rev 57: 103-110, 2008.
    • (2008) Brain Res Rev , vol.57 , pp. 103-110
    • Vinay, L.1    Jean-Xavier, C.2
  • 107
    • 12344330424 scopus 로고    scopus 로고
    • limmaGUI: A graphical user interface for linear modeling of microarray data
    • Wettenhall JM, Smyth GK. limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics 20: 3705-3706, 2004.
    • (2004) Bioinformatics , vol.20 , pp. 3705-3706
    • Wettenhall, J.M.1    Smyth, G.K.2
  • 108
    • 76649110721 scopus 로고    scopus 로고
    • Wienecke J, Ryge J, Westerdahl A-C, Hultborn H, Kiehn O. Gene expression changes in sacral motor neurons during development of spasticity after spinal cord injury. Soc Neurosci Abstr 76.7/HH2, 2007.
    • Wienecke J, Ryge J, Westerdahl A-C, Hultborn H, Kiehn O. Gene expression changes in sacral motor neurons during development of spasticity after spinal cord injury. Soc Neurosci Abstr 76.7/HH2, 2007.
  • 109
    • 22244437531 scopus 로고    scopus 로고
    • Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase
    • Wittmack EK, Rush AM, Hudmon A, Waxman SG, Dib-Hajj SD. Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase. J Neurosci 25: 6621-6630, 2005.
    • (2005) J Neurosci , vol.25 , pp. 6621-6630
    • Wittmack, E.K.1    Rush, A.M.2    Hudmon, A.3    Waxman, S.G.4    Dib-Hajj, S.D.5
  • 111
    • 10044241919 scopus 로고    scopus 로고
    • Use-dependent potentiation of the Nav1.6 sodium channel
    • Zhou W, Goldin AL. Use-dependent potentiation of the Nav1.6 sodium channel. Biophys J 87: 3862-3872, 2004.
    • (2004) Biophys J , vol.87 , pp. 3862-3872
    • Zhou, W.1    Goldin, A.L.2
  • 112
    • 36248942480 scopus 로고    scopus 로고
    • Expression and distribution of all dopamine receptor subtypes (D(1)-D(5)) in the mouse lumbar spinal cord: A real-time polymerase chain reaction and non-autoradiographic in situ hybridization study
    • Zhu H, Clemens S, Sawchuk M, Hochman S. Expression and distribution of all dopamine receptor subtypes (D(1)-D(5)) in the mouse lumbar spinal cord: a real-time polymerase chain reaction and non-autoradiographic in situ hybridization study. Neuroscience 149: 885-897, 2007.
    • (2007) Neuroscience , vol.149 , pp. 885-897
    • Zhu, H.1    Clemens, S.2    Sawchuk, M.3    Hochman, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.