Molecular scissors under light control

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 4, 2010, Pages 1259-1260

  Zaremb, Mindaugas ^a   Siksnys, Virginijus ^a  

^a VILNIUS UNIVERSITY   (Lithuania)

Author keywords

[No Author keywords available]

Indexed keywords

RESTRICTION ENDONUCLEASE;

ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; HUMAN; LIGHT; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN DNA BINDING;

ANIMALS; AZO COMPOUNDS; BIOCATALYSIS; DNA RESTRICTION ENZYMES; ENZYME ACTIVATION; HUMANS; LIGHT; ULTRAVIOLET RAYS;

EID: 76549086524     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0913923107     Document Type: Note

References (20)

1. Gorostiza P, Isacoff EY (2008) Optical switches for remote and noninvasive control of cell signaling. Science 322:395-399.
2. Schierling B, et al. (2009) Controlling the enzymatic activity of a restriction enzyme by light. Proc Natl Acad Sci USA 107:1361-1366.
3. Renner C, Moroder L (2006) Azobenzene as conformational switch in model peptides. ChemBioChem 7:868-878.
4. Muranaka N, Hohsaka T, Sisido M (2002) Photoswitching of peroxidase activity by position-specific incorporation of a photoisomerizable non-natural amino acid into horseradish peroxidase. FEBS Lett 510:10-12.
5. Nakayama K, Endo M, Majima T (2005) A hydrophilic azobenzene bearing amino acid for photochemical control of a restriction enzyme BamHI. Bioconjug Chem 16:1360-1366.
6. Carroll D (2008) Progress and prospects: Zinc-finger nucleases as gene therapy agents. Gene Ther 15:1463-1468.
7. Pâques F, Duchateau P (2007) Meganucleases and DNA double-strand break-induced recombination: Perspectives for gene therapy. Curr Gene Ther 7:49-66.
8. Szczepek M, et al. (2007) Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nat Biotechnol 25:786-793.
9. Li H, Pellenz S, Ulge U, Stoddard BL, Monnat RJ, Jr. (2009) Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins. Nucleic Acids Res 37:1650-1662.
10. Eisenschmidt K, et al. (2005) Developing a programmed restriction endonuclease for highly specific DNA cleavage. Nucleic Acids Res 33:7039-7047.
11. Lombardo A, et al. (2007) Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery. Nat Biotechnol 25:1298-1306.
12. Hockemeyer D, et al. (2009) Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat Biotechnol 27:851-857.
13. Grizot S, et al. (2009) Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease. Nucleic Acids Res 37:5405-5419.
14. Redondo P, et al. (2008) Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases. Nature 456:107-111.
15. + T cells by genome editing using zinc-finger nucleases. Nat Biotechnol 26:808-816.
16. Beumer K, Bhattacharyya G, Bibikova M, Trautman JK, Carroll D (2006) Efficient gene targeting in Drosophila with zinc-finger nucleases. Genetics 172:2391-2403.
17. Pruett-Miller SM, Reading DW, Porter SN, Porteus MH (2009) Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels. PLoS Genet 5:e1000376.
18. Pruett-Miller SM, Connelly JP, Maeder ML, Joung JK, Porteus MH (2008) Comparison of zinc finger nucleases for use in gene targeting in mammalian cells. Mol Ther 16:707-717.
19. Miller JC, et al. (2007) An improved zinc-finger nuclease architecture for highly specific genome editing. Nat Biotechnol 25:778-785.
20. Geel TM, et al. (2009) Endonucleases induced TRAIL-insensitive apoptosis in ovarian carcinoma cells. Exp Cell Res 315:2487-2495.