메뉴 건너뛰기




Volumn 7, Issue 6, 2009, Pages 606-614

Comparison of bioluminescent kinase assays using substrate depletion and product formation

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; LUCIFERASE; PHENYLPYRIMIDINE DERIVATIVE; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN CLK4; PROTEIN CLK4 INHIBITOR; PROTEIN KINASE; PROTEIN KINASE C; PTERIDINONE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 76449108493     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2009.0230     Document Type: Article
Times cited : (36)

References (37)
  • 2
    • 65349122964 scopus 로고    scopus 로고
    • The current status of drug discovery against the human kinome
    • Eglen RM, Reisine T. The current status of drug discovery against the human kinome. Assay Drug Dev Technol 2009;7:22-43.
    • (2009) Assay Drug Dev Technol , vol.7 , pp. 22-43
    • Eglen, R.M.1    Reisine, T.2
  • 3
    • 2442457987 scopus 로고    scopus 로고
    • Evaluation of compound interference in immobilized metal ion affinity-based fluorescence polarization detection with a four million member compound collection
    • Beasley JR, Dunn DA, Walker TL, Parlato SM, Lehrach JM, Auld DS: Evaluation of compound interference in immobilized metal ion affinity-based fluorescence polarization detection with a four million member compound collection. Assay Drug Dev Technol 2003;1:455-459.
    • (2003) Assay Drug Dev Technol , vol.1 , pp. 455-459
    • Beasley, J.R.1    Dunn, D.A.2    Walker, T.L.3    Parlato, S.M.4    Lehrach, J.M.5    Auld, D.S.6
  • 4
    • 2142653053 scopus 로고    scopus 로고
    • A homogeneous fluorescence polarization assay adaptable for a range of protein serine/ threonine and tyrosine kinases
    • Gaudet EA, Huang KS, Zhang Y, Huang W, Mark D, Sportsman JR: A homogeneous fluorescence polarization assay adaptable for a range of protein serine/ threonine and tyrosine kinases. J Biomol Screen 2003;8:164-175.
    • (2003) J Biomol Screen , vol.8 , pp. 164-175
    • Gaudet, E.A.1    Huang, K.S.2    Zhang, Y.3    Huang, W.4    Mark, D.5    Sportsman, J.R.6
  • 5
    • 2442583662 scopus 로고    scopus 로고
    • High-throughput screening with immobilized metal ion affinity-based fluorescence polarization detection, a homogeneous assay for protein kinases
    • Loomans EE, van Doornmalen AM, Wat JW, Zaman GJ: High-throughput screening with immobilized metal ion affinity-based fluorescence polarization detection, a homogeneous assay for protein kinases. Assay Drug Dev Technol 2003;1:445-453.
    • (2003) Assay Drug Dev Technol , vol.1 , pp. 445-453
    • Loomans, E.E.1    Van Doornmalen, A.M.2    Wat, J.W.3    Zaman, G.J.4
  • 6
    • 2442593504 scopus 로고    scopus 로고
    • Immobilized metal ion affinity-based fluorescence polarization (IMAP): Advances in kinase screening
    • Sportsman JR, Gaudet EA, Boge A: Immobilized metal ion affinity-based fluorescence polarization (IMAP): advances in kinase screening. Assay Drug Dev Technol 2004;2:205-214.
    • (2004) Assay Drug Dev Technol , vol.2 , pp. 205-214
    • Sportsman, J.R.1    Gaudet, E.A.2    Boge, A.3
  • 7
    • 2442585687 scopus 로고    scopus 로고
    • Development of a fluorescence polarization AKT serine/threonine kinase assay using an immobilized metal ion affinity-based technology
    • Turek-Etienne TC, Kober TP, Stafford JM, Bryant RW: Development of a fluorescence polarization AKT serine/threonine kinase assay using an immobilized metal ion affinity-based technology. Assay Drug Dev Technol 2003;1:545-553.
    • (2003) Assay Drug Dev Technol , vol.1 , pp. 545-553
    • Turek-Etienne, T.C.1    Kober, T.P.2    Stafford, J.M.3    Bryant, R.W.4
  • 8
    • 0013223828 scopus 로고    scopus 로고
    • A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases
    • Rodems SM, Hamman BD, Lin C, Zhao J, Shah S, Heidary D, et al.: A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases. Assay Drug Dev Technol 2002;1:9-19.
    • (2002) Assay Drug Dev Technol , vol.1 , pp. 9-19
    • Rodems, S.M.1    Hamman, B.D.2    Lin, C.3    Zhao, J.4    Shah, S.5    Heidary, D.6
  • 9
    • 51149107449 scopus 로고    scopus 로고
    • Scintillation proximity assays in highthroughput screening
    • Glickman JF, Schmid A, Ferrand S: Scintillation proximity assays in highthroughput screening. Assay Drug Dev Technol 2008;6:433-455.
    • (2008) Assay Drug Dev Technol , vol.6 , pp. 433-455
    • Glickman, J.F.1    Schmid, A.2    Ferrand, S.3
  • 10
    • 33744912806 scopus 로고    scopus 로고
    • A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5?-diphosphate accumulation
    • Charter NW, Kauffman L, Singh R, Eglen RM: A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5?-diphosphate accumulation. J Biomol Screen 2006;11:390-399.
    • (2006) J Biomol Screen , vol.11 , pp. 390-399
    • Charter, N.W.1    Kauffman, L.2    Singh, R.3    Eglen, R.M.4
  • 11
    • 34249886323 scopus 로고    scopus 로고
    • Development of a Transcreener kinase assay for protein kinase A and demonstration of concordance of data with a filter-binding assay format
    • Huss KL, Blonigen PE, Campbell RM: Development of a Transcreener kinase assay for protein kinase A and demonstration of concordance of data with a filter-binding assay format. J Biomol Screen 2007;12:578-584.
    • (2007) J Biomol Screen , vol.12 , pp. 578-584
    • Huss, K.L.1    Blonigen, P.E.2    Campbell, R.M.3
  • 13
    • 34147210060 scopus 로고    scopus 로고
    • Bioluminescent assays for high-throughput screening
    • Fan F, Wood KV: Bioluminescent assays for high-throughput screening. Assay Drug Dev Technol 2007;5:127-136.
    • (2007) Assay Drug Dev Technol , vol.5 , pp. 127-136
    • Fan, F.1    Wood, K.V.2
  • 14
    • 37749050446 scopus 로고    scopus 로고
    • Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II)
    • Schroter T, Minond D, Weiser A, Dao C, Habel J, Spicer T, et al.: Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II). J Biomol Screen 2008;13:17-28.
    • (2008) J Biomol Screen , vol.13 , pp. 17-28
    • Schroter, T.1    Minond, D.2    Weiser, A.3    Dao, C.4    Habel, J.5    Spicer, T.6
  • 16
    • 2442501720 scopus 로고    scopus 로고
    • Determining appropriate substrate conversion for enzymatic assays in high-throughput screening
    • Wu G, Yuan Y, Hodge CN: Determining appropriate substrate conversion for enzymatic assays in high-throughput screening. J Biomol Screen 2003;8:694-700.
    • (2003) J Biomol Screen , vol.8 , pp. 694-700
    • Wu, G.1    Yuan, Y.2    Hodge, C.N.3
  • 18
    • 64349092077 scopus 로고    scopus 로고
    • A basis for reduced chemical library inhibition of firefl y luciferase obtained from directed evolution
    • Auld DS, Zhang YQ, Southall NT, Rai G, Landsman M, Maclure J, et al.: A basis for reduced chemical library inhibition of firefl y luciferase obtained from directed evolution. J Med Chem 2009;52:1450-1458.
    • (2009) J Med Chem , vol.52 , pp. 1450-1458
    • Auld, D.S.1    Zhang, Y.Q.2    Southall, N.T.3    Rai, G.4    Landsman, M.5    MacLure, J.6
  • 19
    • 2342655502 scopus 로고    scopus 로고
    • Manipulation of alternative splicing by a newly developed inhibitor of Clks
    • Muraki M, Ohkawara B, Hosoya T, Onogi H, Koizumi J, Koizumi T, et al.: Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem 2004;279:24246-24254.
    • (2004) J Biol Chem , vol.279 , pp. 24246-24254
    • Muraki, M.1    Ohkawara, B.2    Hosoya, T.3    Onogi, H.4    Koizumi, J.5    Koizumi, T.6
  • 20
    • 33746789921 scopus 로고    scopus 로고
    • Quantitative high-throughput screening: A titration-based approach that effi-ciently identifi es biological activities in large chemical libraries
    • Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, et al.: Quantitative high-throughput screening: a titration-based approach that effi-ciently identifi es biological activities in large chemical libraries. Proc Natl Acad Sci USA 2006;103:11473-11478.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11473-11478
    • Inglese, J.1    Auld, D.S.2    Jadhav, A.3    Johnson, R.L.4    Simeonov, A.5    Yasgar, A.6
  • 22
    • 20544439816 scopus 로고    scopus 로고
    • Piezo-and solenoid valve-based liquid dispensing for miniaturized assays
    • Niles WD, Coassin PJ: Piezo-and solenoid valve-based liquid dispensing for miniaturized assays. Assay Drug Dev Technol 2005;3:189-202.
    • (2005) Assay Drug Dev Technol , vol.3 , pp. 189-202
    • Niles, W.D.1    Coassin, P.J.2
  • 23
    • 20544456791 scopus 로고    scopus 로고
    • Nanoliter dispensing for uHTS using pin tools
    • Cleveland PH, Koutz PJ: Nanoliter dispensing for uHTS using pin tools. Assay Drug Dev Technol 2005;3:213-225.
    • (2005) Assay Drug Dev Technol , vol.3 , pp. 213-225
    • Cleveland, P.H.1    Koutz, P.J.2
  • 24
    • 67651207389 scopus 로고    scopus 로고
    • Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening
    • Shukla SJ, Nguyen DT, Macarthur R, Simeonov A, Frazee WJ, Hallis TM, et al.: Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening. Assay Drug Dev Technol 2009;7:143-169.
    • (2009) Assay Drug Dev Technol , vol.7 , pp. 143-169
    • Shukla, S.J.1    Nguyen, D.T.2    MacArthur, R.3    Simeonov, A.4    Frazee, W.J.5    Hallis, T.M.6
  • 25
    • 33646272448 scopus 로고    scopus 로고
    • The minimum signifi cant ratio: A statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies
    • Eastwood BJ, Farmen MW, Iversen PW, Craft TJ, Smallwood JK, Garbison KE, et al.: The minimum signifi cant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies. J Biomol Screen 2006;11:253-261.
    • (2006) J Biomol Screen , vol.11 , pp. 253-261
    • Eastwood, B.J.1    Farmen, M.W.2    Iversen, P.W.3    Craft, T.J.4    Smallwood, J.K.5    Garbison, K.E.6
  • 27
    • 54949108677 scopus 로고    scopus 로고
    • PubChem: Integrated platform of small molecules and biological activities
    • Bolton EE, Wang Y, Thiessen PA, Bryant SH: PubChem: integrated platform of small molecules and biological activities. Annu Rep Comput Chem 2008; 4:217-241.
    • (2008) Annu Rep Comput Chem , vol.4 , pp. 217-241
    • Bolton, E.E.1    Wang, Y.2    Thiessen, P.A.3    Bryant, S.H.4
  • 28
    • 76449101035 scopus 로고    scopus 로고
    • http://pubchem.ncbi.nlm.nih.gov/
  • 29
    • 76449109545 scopus 로고    scopus 로고
    • http://www.promega.com/tbs/tm313/tm313.pdf
  • 30
    • 76449092698 scopus 로고    scopus 로고
    • http://www.promega.com/tbs/tb372/tb372.pdf
  • 31
    • 0033598323 scopus 로고    scopus 로고
    • Substituted isoquinolines and quinazolines as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha
    • Chao Q, Deng L, Shih H, Leoni LM, Genini D, Carson DA, et al.: Substituted isoquinolines and quinazolines as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha. J Med Chem 1999;42:3860-3873.
    • (1999) J Med Chem , vol.42 , pp. 3860-3873
    • Chao, Q.1    Deng, L.2    Shih, H.3    Leoni, L.M.4    Genini, D.5    Carson, D.A.6
  • 33
    • 76449104765 scopus 로고    scopus 로고
    • http://www.ncbi.nlm.nih.gov/sites/entrez?db=pcsubstance&term=PCOP
  • 34
    • 71749110422 scopus 로고    scopus 로고
    • Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk)
    • Mott BT, Tanega C, Shen M, Maloney DJ, Shinn P, Leister W, et al.: Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk). Bioorg Med Chem Lett 2009;19:6700-6705.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 6700-6705
    • Mott, B.T.1    Tanega, C.2    Shen, M.3    Maloney, D.J.4    Shinn, P.5    Leister, W.6
  • 36
    • 0020133770 scopus 로고
    • A sensitive and simple assay of starch synthase activity with pyruvate kinase and luciferase
    • Ching TM: A sensitive and simple assay of starch synthase activity with pyruvate kinase and luciferase. Anal Biochem 1982;122:139-143.
    • (1982) Anal Biochem , vol.122 , pp. 139-143
    • Ching, T.M.1
  • 37
    • 0025845205 scopus 로고
    • The pyruvate kinase-coupled assay for ATPases: A critical analysis
    • Jenkins WT: The pyruvate kinase-coupled assay for ATPases: a critical analysis. Anal Biochem 1991;194:136-139.
    • (1991) Anal Biochem , vol.194 , pp. 136-139
    • Jenkins, W.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.