Strategies for the identification of ubiquitin ligase inhibitors

Biochemical Society Transactions

Volumn 38, Issue 1, 2010, Pages 132-136

  Goldenberg, Seth J ^a   Marblestone, Jeffrey G ^a   Mattern, Michael R ^a   Nicholson, Benjamin ^a  

^a Progenra Inc   (United States)

Author keywords

High throughput screening; Homologous with E6 associated protein C terminus (HECT); RING; Ubiquitin protein ligase (E3)

Indexed keywords

BORTEZOMIB; CULLIN; F BOX PROTEIN; LIGASE INHIBITOR; PROTEASOME; PROTEIN MDM2; PROTEIN P53; RING FINGER PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; CLINICAL TRIAL; DEGENERATIVE DISEASE; DRUG RESEARCH; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME IMMOBILIZATION; ENZYME INHIBITION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; HUMAN; MALIGNANT NEOPLASTIC DISEASE; MULTIPLE MYELOMA; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; VIRUS INFECTION;

BIOLOGICAL ASSAY; HUMANS; IMMUNE SYSTEM DISEASES; NEOPLASMS; NEURODEGENERATIVE DISEASES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 76449085144     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0380132     Document Type: Article

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