Mutagenesis alters the catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase

Journal of Biological Chemistry

Volumn 285, Issue 3, 2010, Pages 2113-2119

  Menon, Binuraj R K ^a   Davison, Paul A ^b   Hunter, C Neil ^b   Scrutton, Nigel S ^a   Heyes, Derren J ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED ENZYMES; CATALYTIC MECHANISMS; CONFORMATIONAL CHANGE; CYS RESIDUES; DONOR-ACCEPTOR DISTANCE; DOUBLE BONDS; HYDRIDE TRANSFERS; HYDROGEN TRANSFER; HYDROGEN-TRANSFER REACTIONS; KINETIC MEASUREMENT; LOCAL ACTIVE; MODEL SYSTEM; PROTOCHLOROPHYLLIDE; PROTOCHLOROPHYLLIDE OXIDOREDUCTASE; QUANTUM TUNNELING; RATE LIMITING; SEQUENTIAL ADDITION; SITE DIRECTED MUTAGENESIS; WILD TYPES;

CHLOROPHYLL; MUTAGENESIS; PORPHYRINS; PROTON TRANSFER; SYNTHESIS (CHEMICAL);

ENZYMES;

CYSTEINE; OXIDOREDUCTASE; PROTOCHLOROPHYLLIDE OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; PROTOCHLOROPHYLLIDE REDUCTASE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYANOBACTERIUM; KINETICS; LOW TEMPERATURE; NONHUMAN; PHOTOCHEMISTRY; PRIORITY JOURNAL; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY; WILD TYPE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COLD; ENZYMOLOGY; GENETICS; LASER; LIGHT; METABOLISM; MUTAGENESIS; MUTATION; PROTEIN CONFORMATION; RADIATION EXPOSURE;

BIOCATALYSIS; COLD TEMPERATURE; CYANOBACTERIA; CYSTEINE; KINETICS; LASERS; LIGHT; MODELS, MOLECULAR; MUTAGENESIS; MUTATION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PROTEIN CONFORMATION; SPECTRUM ANALYSIS;

EID: 76249103676     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.071522     Document Type: Article

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