Fraxinus rhynchophylla ethanol extract attenuates carbon tetrachloride-induced liver fibrosis in rats via down-regulating the expressions of uPA, MMP-2, MMP-9 and TIMP-1

Journal of Ethnopharmacology

Volumn 127, Issue 3, 2010, Pages 606-613

  Peng, Wen Huang ^a   Tien, Yun Chen ^a   Huang, Chih Yang ^a   Huang, Tai Hung ^a   Liao, Jung Chun ^a   Kuo, Chao Lin ^a   Lin, Ying Chih ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b JEN TEH JUNIOR COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Anti oxidant enzymes; Fraxinus rhynchophylla; Hepatic fibrosis; Hepatoprotection

Indexed keywords

ALCOHOL; CARBON TETRACHLORIDE; CATALASE; ESCULETIN; FRAXINUS RHYNCHOPHYLLA EXTRACT; GELATINASE A; GELATINASE B; GLUTATHIONE PEROXIDASE; LIVER PROTECTIVE AGENT; PLANT EXTRACT; SILYMARIN; SUPEROXIDE DISMUTASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SWELLING; CELL VACUOLE; CONNECTIVE TISSUE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; FRAXINUS; FRAXINUS RHYNCHOPHYLLA; HISTOPATHOLOGY; LIVER CELL; LIVER FIBROSIS; LIVER FUNCTION; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LYMPHOCYTIC INFILTRATION; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CARBON TETRACHLORIDE POISONING; DOWN-REGULATION; FRAXINUS; GENE EXPRESSION; LIVER; LIVER CIRRHOSIS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SILYMARIN; TISSUE INHIBITOR OF METALLOPROTEINASE-1; UMBELLIFERONES; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

FRAXINUS RYNCHOPHYLLA; RATTUS;

EID: 76149087418     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.12.016     Document Type: Article

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