Highly regio- and stereoselective synthesis of α-(N-Alkyl-N-p- toluenesulfonyl)-β-bromo-ketones via Ni(OAc)2-catalyzed aminobromination of chalcones

Chemical Biology and Drug Design

Volumn 75, Issue 3, 2010, Pages 269-276

  Sun, Hao ^a   Zhi, San Jun ^a   Han, Jian Lin ^a   Li, Guigen ^a,b   Pan, Yi ^a  

^a NANJING UNIVERSITY   (China)

^b TEXAS TECH UNIVERSITY   (United States)

Author keywords

, unsaturated; Aminohalogenation; Ketones; N alkyl p toluenesulfonamide; Nickel acetate

Indexed keywords

3 BROMO 1 (4 BROMOPHENYL) 3 PHENYL 2 (N ETHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 1 (4 BROMOPHENYL) 3 PHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 1 (4 CHLOROPHENYL) 3 PHENYL 2 (N ETHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 1 (4 CHLOROPHENYL) 3 PHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 1 (4 METHYLPHENYL) 3 (4 METHYLPHENYL) 2 (N ETHYLTOSYLAMINO) 1 ONE; 3 BROMO 1 (4 METHYLPHENYL) 3 (4 METHYLPHENYL) 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 1 (4 METHYLPHENYL) 3 PHENYL 2 (N ETHYLTOSYLAMINO) 1 ONE; 3 BROMO 1 (4 METHYLPHENYL) 3 PHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 1,3 DIPHENYL 2 (N ETHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 1,3 DIPHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (2 CHLOROPHENYL) 1 PHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (4 BROMOPHENYL) 1 PHENYL 2 (N ETHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (4 BROMOPHENYL) 1 PHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (4 CHLOROPHENYL) 1 (4 METHYLPHENYL) 2 (N ETHYLTOSYLAMINO) 1 ONE; 3 BROMO 3 (4 CHLOROPHENYL) 1 (4 METHYLPHENYL) 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (4 CHLOROPHENYL) 1 PHENYL 2 (N ETHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (4 CHLOROPHENYL) 1 PHENYL 2 (N METHYLTOSYLMINO)PROPAN 1 ONE; 3 BROMO 3 (4 FLUOROPHENYL) 1 PHENYL 2 (N ETHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (4 FLUOROPHENYL) 1 PHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; 3 BROMO 3 (4 METHYLPHENYL) 1 PHENYL 2 (N ETHYLTOSYLAMINO) 1 ONE; 3 BROMO 3 (4 METHYLPHENYL) 1 PHENYL 2 (N METHYLTOSYLAMINO)PROPAN 1 ONE; CHALCONE DERIVATIVE; KETONE DERIVATIVE; NICKEL; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

ACETATES; CATALYSIS; CHALCONES; CRYSTALLOGRAPHY, X-RAY; HALOGENATION; KETONES; MOLECULAR CONFORMATION; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM; SULFONAMIDES;

EID: 76049103380     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00938.x     Document Type: Article

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