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Volumn 289, Issue 1, 2010, Pages 11-22

Mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in carcinogenesis

Author keywords

Cancer; IGF2; Loss of heterozygosity; M6P IGF2R; Mutation

Indexed keywords

MANNOSE 6 PHOSPHATE; METHIONINE; SOMATOMEDIN B RECEPTOR;

EID: 75949130596     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.06.036     Document Type: Review
Times cited : (53)

References (99)
  • 1
    • 0033054633 scopus 로고    scopus 로고
    • Regulation of soluble insulin-like growth factor II/mannose 6-phosphate receptor in human serum: measurement by enzyme-linked immunosorbent assay
    • Costello M., Baxter R.C., and Scott C.D. Regulation of soluble insulin-like growth factor II/mannose 6-phosphate receptor in human serum: measurement by enzyme-linked immunosorbent assay. J. Clin. Endocrinol. Metab. 84 (1999) 611-617
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 611-617
    • Costello, M.1    Baxter, R.C.2    Scott, C.D.3
  • 2
    • 0032775466 scopus 로고    scopus 로고
    • Genomic structure of the human M6P/IGF2 receptor
    • Killian J.K., and Jirtle R.L. Genomic structure of the human M6P/IGF2 receptor. Mamm. Genome 10 (1999) 74-77
    • (1999) Mamm. Genome , vol.10 , pp. 74-77
    • Killian, J.K.1    Jirtle, R.L.2
  • 3
    • 0023856926 scopus 로고
    • The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells
    • Oshima A., Nolan C.M., Kyle J.W., Grubb J.H., and Sly W.S. The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells. J. Biol. Chem. 263 (1988) 2553-2562
    • (1988) J. Biol. Chem. , vol.263 , pp. 2553-2562
    • Oshima, A.1    Nolan, C.M.2    Kyle, J.W.3    Grubb, J.H.4    Sly, W.S.5
  • 5
    • 1442299204 scopus 로고    scopus 로고
    • The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system
    • Hawkes C., and Kar S. The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system. Brain Res. Rev. 44 (2004) 117-140
    • (2004) Brain Res. Rev. , vol.44 , pp. 117-140
    • Hawkes, C.1    Kar, S.2
  • 7
    • 0033609918 scopus 로고    scopus 로고
    • Mannose-6-phosphate/insulin-like growth factor II receptor mediates internalization and degradation of leukemia inhibitory factor but not signal transduction
    • Blanchard F., Duplomb L., Raher S., Vusio P., Hoflack B., Jacques Y., and Godard A. Mannose-6-phosphate/insulin-like growth factor II receptor mediates internalization and degradation of leukemia inhibitory factor but not signal transduction. J. Biol. Chem. 274 (1999) 24685-24693
    • (1999) J. Biol. Chem. , vol.274 , pp. 24685-24693
    • Blanchard, F.1    Duplomb, L.2    Raher, S.3    Vusio, P.4    Hoflack, B.5    Jacques, Y.6    Godard, A.7
  • 8
    • 0023860003 scopus 로고
    • Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors
    • Lee S.J., and Nathans D. Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors. J. Biol. Chem. 263 (1988) 3521-3527
    • (1988) J. Biol. Chem. , vol.263 , pp. 3521-3527
    • Lee, S.J.1    Nathans, D.2
  • 9
    • 0025119503 scopus 로고
    • Interactions of cathepsin-D and insulin-like growth factor-II (IGF-II) on the IGF-II/mannose-6-phosphate receptor in human breast cancer cells and possible consequences on mitogenic activity of IGF-II
    • Mathieu M., Rochefort H., Barenton B., Prebois C., and Vignon F. Interactions of cathepsin-D and insulin-like growth factor-II (IGF-II) on the IGF-II/mannose-6-phosphate receptor in human breast cancer cells and possible consequences on mitogenic activity of IGF-II. Mol. Endocrinol. 4 (1990) 1327-1335
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1327-1335
    • Mathieu, M.1    Rochefort, H.2    Barenton, B.3    Prebois, C.4    Vignon, F.5
  • 10
    • 0026059613 scopus 로고
    • Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor
    • Dennis P.A., and Rifkin D.B. Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc. Natl. Acad. Sci. USA 88 (1991) 580-584
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 580-584
    • Dennis, P.A.1    Rifkin, D.B.2
  • 11
    • 0024097574 scopus 로고
    • Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse
    • Laureys G., Barton D.E., Ullrich A., and Francke U. Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse. Genomics 3 (1988) 224-229
    • (1988) Genomics , vol.3 , pp. 224-229
    • Laureys, G.1    Barton, D.E.2    Ullrich, A.3    Francke, U.4
  • 13
    • 0031456570 scopus 로고    scopus 로고
    • Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid
    • Kang J.X., Li Y., and Leaf A. Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid. Proc. Natl. Acad. Sci. USA 94 (1997) 13671-13676
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13671-13676
    • Kang, J.X.1    Li, Y.2    Leaf, A.3
  • 14
    • 33947685420 scopus 로고    scopus 로고
    • The cation-independent mannose 6-phosphate receptor is involved in lysosomal delivery of serglycin
    • Lemansky P., Fester I., Smolenova E., Uhlander C., and Hasilik A. The cation-independent mannose 6-phosphate receptor is involved in lysosomal delivery of serglycin. J. Leukoc. Biol. 81 (2007) 1149-1158
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1149-1158
    • Lemansky, P.1    Fester, I.2    Smolenova, E.3    Uhlander, C.4    Hasilik, A.5
  • 15
    • 42949156428 scopus 로고    scopus 로고
    • Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation
    • Wood R.J., and Hulett M.D. Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation. J. Biol. Chem. 283 (2008) 4165-4176
    • (2008) J. Biol. Chem. , vol.283 , pp. 4165-4176
    • Wood, R.J.1    Hulett, M.D.2
  • 16
    • 0041834587 scopus 로고    scopus 로고
    • The secreted glycoprotein CREG inhibits cell growth dependent on the mannose-6-phosphate/insulin-like growth factor II receptor
    • Di Bacco A., and Gill G. The secreted glycoprotein CREG inhibits cell growth dependent on the mannose-6-phosphate/insulin-like growth factor II receptor. Oncogene 22 (2003) 5436-5445
    • (2003) Oncogene , vol.22 , pp. 5436-5445
    • Di Bacco, A.1    Gill, G.2
  • 17
    • 0028575985 scopus 로고
    • Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality
    • Lau M.M., Stewart C.E., Liu Z., Bhatt H., Rotwein P., and Stewart C.L. Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev. 8 (1994) 2953-2963
    • (1994) Genes Dev. , vol.8 , pp. 2953-2963
    • Lau, M.M.1    Stewart, C.E.2    Liu, Z.3    Bhatt, H.4    Rotwein, P.5    Stewart, C.L.6
  • 18
    • 0027999284 scopus 로고
    • Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene
    • Wang Z.Q., Fung M.R., Barlow D.P., and Wagner E.F. Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene. Nature 372 (1994) 464-467
    • (1994) Nature , vol.372 , pp. 464-467
    • Wang, Z.Q.1    Fung, M.R.2    Barlow, D.P.3    Wagner, E.F.4
  • 19
    • 0030221121 scopus 로고    scopus 로고
    • Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds
    • Ludwig T., Eggenschwiler J., Fisher P., D'Ercole A.J., Davenport M.L., and Efstratiadis A. Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds. Dev. Biol. 177 (1996) 517-535
    • (1996) Dev. Biol. , vol.177 , pp. 517-535
    • Ludwig, T.1    Eggenschwiler, J.2    Fisher, P.3    D'Ercole, A.J.4    Davenport, M.L.5    Efstratiadis, A.6
  • 20
    • 32944459267 scopus 로고    scopus 로고
    • Delayed onset of IGF2-induced mammary tumors in IGF2R mice
    • Wise T.L., and Pravtcheva D.D. Delayed onset of IGF2-induced mammary tumors in IGF2R mice. Cancer Res. 66 (2006) 1327-1336
    • (2006) Cancer Res. , vol.66 , pp. 1327-1336
    • Wise, T.L.1    Pravtcheva, D.D.2
  • 21
    • 0033571113 scopus 로고    scopus 로고
    • Decreased insulin-like growth factor-II/mannose 6-phosphate receptor expression enhances tumorigenicity in JEG-3 cells
    • O'Gorman D.B., Costello M., Weiss J., Firth S.M., and Scott C.D. Decreased insulin-like growth factor-II/mannose 6-phosphate receptor expression enhances tumorigenicity in JEG-3 cells. Cancer Res. 59 (1999) 5692-5694
    • (1999) Cancer Res. , vol.59 , pp. 5692-5694
    • O'Gorman, D.B.1    Costello, M.2    Weiss, J.3    Firth, S.M.4    Scott, C.D.5
  • 22
    • 0033566056 scopus 로고    scopus 로고
    • Expression of the wild type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells
    • Souza R.F., Wang S., Thakar M., Smolinski K.N., Yin J., Zhou T.T., Kong D., Abraham J.M., Toretsky J.A., and Meltzer S.J. Expression of the wild type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells. Oncogene 18 (1999) 4063-4068
    • (1999) Oncogene , vol.18 , pp. 4063-4068
    • Souza, R.F.1    Wang, S.2    Thakar, M.3    Smolinski, K.N.4    Yin, J.5    Zhou, T.T.6    Kong, D.7    Abraham, J.M.8    Toretsky, J.A.9    Meltzer, S.J.10
  • 23
    • 3042714343 scopus 로고    scopus 로고
    • Decreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells
    • art. no. 18
    • Z.H. Chen, Y.L. Ge, N. Landman, J.X. Kang, Decreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells, BMC Cancer 2 (2002) (art. no. 18).
    • (2002) BMC Cancer , vol.2
    • Chen, Z.H.1    Ge, Y.L.2    Landman, N.3    Kang, J.X.4
  • 24
    • 11244346678 scopus 로고    scopus 로고
    • Demonstration of tumor suppression by mannose 6-phosphate/insulin-like growth factor 2 receptor
    • Li J., and Sahagian G.G. Demonstration of tumor suppression by mannose 6-phosphate/insulin-like growth factor 2 receptor. Oncogene 23 (2004) 9359-9368
    • (2004) Oncogene , vol.23 , pp. 9359-9368
    • Li, J.1    Sahagian, G.G.2
  • 25
    • 64249094725 scopus 로고    scopus 로고
    • The mannose 6-phosphate/insulin-like growth factor II receptor restricts the tumourigenicity and invasiveness of squamous cell carcinoma cells
    • Probst O.C., Puxbaum V., Svoboda B., Leksa V., Stockinger H., Mikula M., Mikulits W., and Mach L. The mannose 6-phosphate/insulin-like growth factor II receptor restricts the tumourigenicity and invasiveness of squamous cell carcinoma cells. Int. J. Cancer 124 (2009) 2559-2567
    • (2009) Int. J. Cancer , vol.124 , pp. 2559-2567
    • Probst, O.C.1    Puxbaum, V.2    Svoboda, B.3    Leksa, V.4    Stockinger, H.5    Mikula, M.6    Mikulits, W.7    Mach, L.8
  • 26
    • 0037372016 scopus 로고    scopus 로고
    • Opposing roles for the insulin-like growth factor (IGF)-II and mannose 6-phosphate (Man-6-P) binding activities of the IGF-II/Man-6-P receptor in the growth of prostate cancer cells
    • Schaffer B.S., Lin M.F., Byrd J.C., Park J.H., and MacDonald R.G. Opposing roles for the insulin-like growth factor (IGF)-II and mannose 6-phosphate (Man-6-P) binding activities of the IGF-II/Man-6-P receptor in the growth of prostate cancer cells. Endocrinology 144 (2003) 955-966
    • (2003) Endocrinology , vol.144 , pp. 955-966
    • Schaffer, B.S.1    Lin, M.F.2    Byrd, J.C.3    Park, J.H.4    MacDonald, R.G.5
  • 27
    • 0025166061 scopus 로고
    • Characterization of chromosomal anomalies in human breast cancer. A comparison of 30 paradiploid cases with few chromosome changes
    • Dutrillaux B., Gerbault-Seureau M., and Zafrani B. Characterization of chromosomal anomalies in human breast cancer. A comparison of 30 paradiploid cases with few chromosome changes. Cancer Genet. Cytogenet. 49 (1990) 203-217
    • (1990) Cancer Genet. Cytogenet. , vol.49 , pp. 203-217
    • Dutrillaux, B.1    Gerbault-Seureau, M.2    Zafrani, B.3
  • 28
    • 0025321563 scopus 로고
    • Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas
    • Lee J.H., Kavanagh J.J., Wildrick D.M., Wharton J.T., and Blick M. Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas. Cancer Res. 50 (1990) 2724-2728
    • (1990) Cancer Res. , vol.50 , pp. 2724-2728
    • Lee, J.H.1    Kavanagh, J.J.2    Wildrick, D.M.3    Wharton, J.T.4    Blick, M.5
  • 29
    • 0026699258 scopus 로고
    • Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers
    • Saito S., Saito H., Koi S., Sagae S., Kudo R., Saito J., Noda K., and Nakamura Y. Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers. Cancer Res. 52 (1992) 5815-5817
    • (1992) Cancer Res. , vol.52 , pp. 5815-5817
    • Saito, S.1    Saito, H.2    Koi, S.3    Sagae, S.4    Kudo, R.5    Saito, J.6    Noda, K.7    Nakamura, Y.8
  • 30
    • 0026049238 scopus 로고
    • Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma
    • Millikin D., Meese E., Vogelstein B., Witkowski C., and Trent J. Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma. Cancer Res. 51 (1991) 5449-5453
    • (1991) Cancer Res. , vol.51 , pp. 5449-5453
    • Millikin, D.1    Meese, E.2    Vogelstein, B.3    Witkowski, C.4    Trent, J.5
  • 34
    • 0030716258 scopus 로고    scopus 로고
    • Loss of heterozygosity at the mannose-6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinoma
    • Chappell S.A., Walsh T., Walker R.A., and Shaw J.A. Loss of heterozygosity at the mannose-6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinoma. Br. J. Cancer 76 (1997) 1558-1561
    • (1997) Br. J. Cancer , vol.76 , pp. 1558-1561
    • Chappell, S.A.1    Walsh, T.2    Walker, R.A.3    Shaw, J.A.4
  • 35
    • 0037333594 scopus 로고    scopus 로고
    • Mannose-6-phosphate/insulin-like growth factor-II receptor expression levels during the progression from normal human mammary tissue to invasive breast carcinomas
    • Berthe M.L., Esslimani Sahla M., Rogers P., Gleizes M., Lemamy G.J., Brouillet J.P., and Rochefort H. Mannose-6-phosphate/insulin-like growth factor-II receptor expression levels during the progression from normal human mammary tissue to invasive breast carcinomas. Eur. J. Cancer 39 (2003) 635-642
    • (2003) Eur. J. Cancer , vol.39 , pp. 635-642
    • Berthe, M.L.1    Esslimani Sahla, M.2    Rogers, P.3    Gleizes, M.4    Lemamy, G.J.5    Brouillet, J.P.6    Rochefort, H.7
  • 36
    • 34447509519 scopus 로고    scopus 로고
    • Radiation-induced posttranscriptional control of M6P/IGF2R expression in breast cancer cell lines
    • Iwamoto K.S., and Barber C.L. Radiation-induced posttranscriptional control of M6P/IGF2R expression in breast cancer cell lines. Mol. Carcinogen. 46 (2007) 497-502
    • (2007) Mol. Carcinogen. , vol.46 , pp. 497-502
    • Iwamoto, K.S.1    Barber, C.L.2
  • 37
    • 0029031943 scopus 로고
    • Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors
    • de Souza A.T., Hankins G.R., Washington M.K., Fine R.L., Orton T.C., and Jirtle R.L. Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors. Oncogene 10 (1995) 1725-1729
    • (1995) Oncogene , vol.10 , pp. 1725-1729
    • de Souza, A.T.1    Hankins, G.R.2    Washington, M.K.3    Fine, R.L.4    Orton, T.C.5    Jirtle, R.L.6
  • 38
    • 0032991094 scopus 로고    scopus 로고
    • Failure to detect genetic alteration of the mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) gene in hepatocellular carcinomas in Japan
    • Wada I., Kanada H., Nomura K., Kato Y., Machinami R., and Kitagawa T. Failure to detect genetic alteration of the mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) gene in hepatocellular carcinomas in Japan. Hepatology 29 (1999) 1718-1721
    • (1999) Hepatology , vol.29 , pp. 1718-1721
    • Wada, I.1    Kanada, H.2    Nomura, K.3    Kato, Y.4    Machinami, R.5    Kitagawa, T.6
  • 40
    • 0029100622 scopus 로고
    • Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcinoma
    • Sue S.R., Chari R.S., Kong F.M., Mills J.J., Fine R.L., Jirtle R.L., and Meyers W.C. Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcinoma. Ann. Surg. 222 (1995) 171-178
    • (1995) Ann. Surg. , vol.222 , pp. 171-178
    • Sue, S.R.1    Chari, R.S.2    Kong, F.M.3    Mills, J.J.4    Fine, R.L.5    Jirtle, R.L.6    Meyers, W.C.7
  • 41
    • 0028804071 scopus 로고
    • M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
    • De Souza A.T., Hankins G.R., Washington M.K., Orton T.C., and Jirtle R.L. M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nat. Genet. 11 (1995) 447-449
    • (1995) Nat. Genet. , vol.11 , pp. 447-449
    • De Souza, A.T.1    Hankins, G.R.2    Washington, M.K.3    Orton, T.C.4    Jirtle, R.L.5
  • 42
    • 41149151320 scopus 로고    scopus 로고
    • Clinical significance of loss of heterozygosity for M6P/IGF2R in patients with primary hepatocellular carcinoma
    • Jang H.S., Kang K.M., Choi B.O., Chai G.Y., Hong S.C., Ha W.S., and Jirtle R.L. Clinical significance of loss of heterozygosity for M6P/IGF2R in patients with primary hepatocellular carcinoma. World J. Gastroenterol. 14 (2008) 1394-1398
    • (2008) World J. Gastroenterol. , vol.14 , pp. 1394-1398
    • Jang, H.S.1    Kang, K.M.2    Choi, B.O.3    Chai, G.Y.4    Hong, S.C.5    Ha, W.S.6    Jirtle, R.L.7
  • 43
    • 0030928653 scopus 로고    scopus 로고
    • Loss of the gene encoding mannose 6-phosphate/insulin-like growth factor II receptor is an early event in liver carcinogenesis
    • Yamada T., Desouza A.T., Finkelstein S., and Jirtle R.L. Loss of the gene encoding mannose 6-phosphate/insulin-like growth factor II receptor is an early event in liver carcinogenesis. Proc. Natl. Acad. Sci. USA 94 (1997) 10351-10355
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10351-10355
    • Yamada, T.1    Desouza, A.T.2    Finkelstein, S.3    Jirtle, R.L.4
  • 44
    • 0030609202 scopus 로고    scopus 로고
    • Deletion of the M6P/IGF2R gene in primary hepatocellular carcinoma
    • Piao Z., Choi Y., Park C., Lee W.J., Park J.H., and Kim H. Deletion of the M6P/IGF2R gene in primary hepatocellular carcinoma. Cancer Lett. 120 (1997) 39-43
    • (1997) Cancer Lett. , vol.120 , pp. 39-43
    • Piao, Z.1    Choi, Y.2    Park, C.3    Lee, W.J.4    Park, J.H.5    Kim, H.6
  • 47
    • 66249120367 scopus 로고    scopus 로고
    • F.O. Desmet, D. Hamroun, M. Lalande, G. Collod-Béroud, M. Claustres, C. Béroud, Human splicing finder: an online bioinformatics tool to predict splicing signals, Nucl. Acids Res., doi:10.1093/nar/gkp215.
  • 48
    • 0033736831 scopus 로고    scopus 로고
    • Mutation analysis of the gene encoding the human mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in human cell lines resistant to growth inhibition by transforming growth factor beta(1) (TGF-β1)
    • Gemma A., Hosoya Y., Uematsu K., Seike M., Kurimoto F., Yoshimura A., Shibuya M., and Kudoh S. Mutation analysis of the gene encoding the human mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in human cell lines resistant to growth inhibition by transforming growth factor beta(1) (TGF-β1). Lung Cancer 30 (2000) 91-98
    • (2000) Lung Cancer , vol.30 , pp. 91-98
    • Gemma, A.1    Hosoya, Y.2    Uematsu, K.3    Seike, M.4    Kurimoto, F.5    Yoshimura, A.6    Shibuya, M.7    Kudoh, S.8
  • 50
    • 0034745791 scopus 로고    scopus 로고
    • Loss of heterozygosity at the mannose 6-phosphate/insulin-like growth factor 2 receptor locus: a frequent but late event in adrenocortical tumorigenesis
    • Leboulleux S., Gaston V., Boulle N., Le Bouc Y., and Gicquel C. Loss of heterozygosity at the mannose 6-phosphate/insulin-like growth factor 2 receptor locus: a frequent but late event in adrenocortical tumorigenesis. Eur. J. Endocrinol. 144 (2001) 163-168
    • (2001) Eur. J. Endocrinol. , vol.144 , pp. 163-168
    • Leboulleux, S.1    Gaston, V.2    Boulle, N.3    Le Bouc, Y.4    Gicquel, C.5
  • 51
    • 0033959501 scopus 로고    scopus 로고
    • Stable amino-acid sequence of the mannose-6-phosphate/insulin-like growth-factor II receptor in ovarian carcinomas with loss of heterozygosity and in breast cancer cell lines
    • Rey J.M., Theillet C., Brouillet J.P., and Rochefort H. Stable amino-acid sequence of the mannose-6-phosphate/insulin-like growth-factor II receptor in ovarian carcinomas with loss of heterozygosity and in breast cancer cell lines. Int. J. Cancer 85 (2000) 466-473
    • (2000) Int. J. Cancer , vol.85 , pp. 466-473
    • Rey, J.M.1    Theillet, C.2    Brouillet, J.P.3    Rochefort, H.4
  • 53
    • 34248389804 scopus 로고    scopus 로고
    • Insulin-like growth factor 2 and its receptors (IGF 1R and IGF 2R/mannose-6-phosphate) in endometrial carcinoma
    • Pavelić J., Radaković B., and Pavelić K. Insulin-like growth factor 2 and its receptors (IGF 1R and IGF 2R/mannose-6-phosphate) in endometrial carcinoma. Gynecol. Oncol. 105 (2007) 727-735
    • (2007) Gynecol. Oncol. , vol.105 , pp. 727-735
    • Pavelić, J.1    Radaković, B.2    Pavelić, K.3
  • 54
    • 32644435468 scopus 로고    scopus 로고
    • High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer
    • Huang Z., Wen Y., Shandilya R., Marks R.J., Berchuck A., and Murphy S.K. High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer. Nucl. Acids Res. 34 (2006) 555-563
    • (2006) Nucl. Acids Res. , vol.34 , pp. 555-563
    • Huang, Z.1    Wen, Y.2    Shandilya, R.3    Marks, R.J.4    Berchuck, A.5    Murphy, S.K.6
  • 57
    • 0038333245 scopus 로고    scopus 로고
    • Tumors with microsatellite instability: many mutations, targets and paradoxes
    • Perucho M. Tumors with microsatellite instability: many mutations, targets and paradoxes. Oncogene 22 (2003) 2223-2225
    • (2003) Oncogene , vol.22 , pp. 2223-2225
    • Perucho, M.1
  • 61
    • 0033946516 scopus 로고    scopus 로고
    • Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: a study of the TGF beta RII, Bax, HMSH3, HMSH6, IGHIIR and BLM Genes
    • Calin G.A., Gafa R., Tibiletti M.G., Herlea V., Becheanu G., Cavazzini L., Barbanti-Brodano G., Nenci I., Negrini M., and Lanza G. Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: a study of the TGF beta RII, Bax, HMSH3, HMSH6, IGHIIR and BLM Genes. Int. J. Cancer 89 (2000) 230-235
    • (2000) Int. J. Cancer , vol.89 , pp. 230-235
    • Calin, G.A.1    Gafa, R.2    Tibiletti, M.G.3    Herlea, V.4    Becheanu, G.5    Cavazzini, L.6    Barbanti-Brodano, G.7    Nenci, I.8    Negrini, M.9    Lanza, G.10
  • 64
    • 33645933898 scopus 로고    scopus 로고
    • Microsatellite instability and mismatch repair target gene mutation in cell lines and xenografts of prostate cancer
    • Sun X., Shen C., Vessela R.L., and Dong J.-T. Microsatellite instability and mismatch repair target gene mutation in cell lines and xenografts of prostate cancer. Prostate 66 (2006) 660-666
    • (2006) Prostate , vol.66 , pp. 660-666
    • Sun, X.1    Shen, C.2    Vessela, R.L.3    Dong, J.-T.4
  • 66
    • 0037439959 scopus 로고    scopus 로고
    • Insulin-like growth factor II receptor gene-167 genotype increases the risk of oral squamous cell carcinoma in humans
    • Zavras A.I., Pitiphat W., Wu T., Cartsos V., Lam A., Douglass C.W., and Diehl S.R. Insulin-like growth factor II receptor gene-167 genotype increases the risk of oral squamous cell carcinoma in humans. Cancer Res. 63 (2003) 296-297
    • (2003) Cancer Res. , vol.63 , pp. 296-297
    • Zavras, A.I.1    Pitiphat, W.2    Wu, T.3    Cartsos, V.4    Lam, A.5    Douglass, C.W.6    Diehl, S.R.7
  • 68
    • 34548078061 scopus 로고    scopus 로고
    • Analysis of genes critical for growth regulation identifies insulin-like growth factor 2 receptor variations with possible functional significance as risk factors for osteosarcoma
    • Savage S.A., Woodson K., Walk E., Modi W., Liao J., Douglass C., Hoover R.N., and Chanock S.J. Analysis of genes critical for growth regulation identifies insulin-like growth factor 2 receptor variations with possible functional significance as risk factors for osteosarcoma. Cancer Epidemiol. Biomar. Prev. 16 (2007) 1667-1674
    • (2007) Cancer Epidemiol. Biomar. Prev. , vol.16 , pp. 1667-1674
    • Savage, S.A.1    Woodson, K.2    Walk, E.3    Modi, W.4    Liao, J.5    Douglass, C.6    Hoover, R.N.7    Chanock, S.J.8
  • 72
    • 0026098090 scopus 로고
    • The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus
    • Barlow D.P., Stoger R., Herrmann B.G., Saito K., and Schweifer N. The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature 349 (1991) 84-87
    • (1991) Nature , vol.349 , pp. 84-87
    • Barlow, D.P.1    Stoger, R.2    Herrmann, B.G.3    Saito, K.4    Schweifer, N.5
  • 73
    • 0035336255 scopus 로고    scopus 로고
    • Allelic IGF2R repression does not correlate with expression of antisense RNA in human extraembryonic tissues
    • Oudejans C.B., Westerman B., Wouters D., Gooyer S., Leegwater P.A., van Wijk I.J., and Sleutels F. Allelic IGF2R repression does not correlate with expression of antisense RNA in human extraembryonic tissues. Genomics 73 (2001) 331-337
    • (2001) Genomics , vol.73 , pp. 331-337
    • Oudejans, C.B.1    Westerman, B.2    Wouters, D.3    Gooyer, S.4    Leegwater, P.A.5    van Wijk, I.J.6    Sleutels, F.7
  • 74
    • 0036124466 scopus 로고    scopus 로고
    • Shared role for differentially methylated domains of imprinted genes
    • Reinhart B., Eljanne M., and Chaillet J.R. Shared role for differentially methylated domains of imprinted genes. Mol. Cell. Biol. 22 (2002) 2089-2098
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2089-2098
    • Reinhart, B.1    Eljanne, M.2    Chaillet, J.R.3
  • 75
    • 0038104379 scopus 로고    scopus 로고
    • Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions
    • Sandovici I., Leppert M., Red Hawk P., Suarez A., Linares Y., and Sapienza C. Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions. Hum. Mol. Genet. 12 (2003) 1569-1578
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1569-1578
    • Sandovici, I.1    Leppert, M.2    Red Hawk, P.3    Suarez, A.4    Linares, Y.5    Sapienza, C.6
  • 76
    • 5444247848 scopus 로고    scopus 로고
    • Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse
    • Vu T.H., Li T., and Hoffman A.R. Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse. Hum. Mol. Genet. 13 (2004) 2233-2245
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2233-2245
    • Vu, T.H.1    Li, T.2    Hoffman, A.R.3
  • 77
    • 0033534489 scopus 로고    scopus 로고
    • The rate of internalization of the mannose 6-phosphate/insulin-like growth factor II receptor is enhanced by multivalent ligand binding
    • York S.J., Arneson L.S., Gregory W.T., Dahms N.M., and Kornfeld S. The rate of internalization of the mannose 6-phosphate/insulin-like growth factor II receptor is enhanced by multivalent ligand binding. J. Biol. Chem. 274 (1999) 1164-1171
    • (1999) J. Biol. Chem. , vol.274 , pp. 1164-1171
    • York, S.J.1    Arneson, L.S.2    Gregory, W.T.3    Dahms, N.M.4    Kornfeld, S.5
  • 78
    • 0034705596 scopus 로고    scopus 로고
    • Dimerization of the insulin-like growth factor II/mannose 6-phosphate receptor
    • Byrd J.C., Park J.H., Schaffer B.S., Garmroudi F., and MacDonald R.G. Dimerization of the insulin-like growth factor II/mannose 6-phosphate receptor. J. Biol. Chem. 275 (2000) 18647-18656
    • (2000) J. Biol. Chem. , vol.275 , pp. 18647-18656
    • Byrd, J.C.1    Park, J.H.2    Schaffer, B.S.3    Garmroudi, F.4    MacDonald, R.G.5
  • 79
    • 20444417789 scopus 로고    scopus 로고
    • Domain interactions of the mannose 6-phosphate/insulin-like growth factor II receptor
    • Kreiling J.L., Byrd J.C., and MacDonald R.G. Domain interactions of the mannose 6-phosphate/insulin-like growth factor II receptor. J. Biol. Chem. 280 (2005) 21067-21077
    • (2005) J. Biol. Chem. , vol.280 , pp. 21067-21077
    • Kreiling, J.L.1    Byrd, J.C.2    MacDonald, R.G.3
  • 80
    • 62149151218 scopus 로고    scopus 로고
    • High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose 6-phosphate/insulin-like growth factor II receptor
    • Hartman M.A., Kreiling J.L., Byrd J.C., and MacDonald R.G. High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose 6-phosphate/insulin-like growth factor II receptor. FEBS J. 276 (2009) 1915-1929
    • (2009) FEBS J. , vol.276 , pp. 1915-1929
    • Hartman, M.A.1    Kreiling, J.L.2    Byrd, J.C.3    MacDonald, R.G.4
  • 81
    • 0035968216 scopus 로고    scopus 로고
    • Real time kinetics of insulin-like growth factor II (IGF-II) interaction with the IGF-II/mannose 6-phosphate receptor: the effects of domain 13 and pH
    • Linnell J., Groeger G., and Hassan A.B. Real time kinetics of insulin-like growth factor II (IGF-II) interaction with the IGF-II/mannose 6-phosphate receptor: the effects of domain 13 and pH. J. Biol. Chem. 276 (2001) 23986-23991
    • (2001) J. Biol. Chem. , vol.276 , pp. 23986-23991
    • Linnell, J.1    Groeger, G.2    Hassan, A.B.3
  • 83
    • 0036499988 scopus 로고    scopus 로고
    • Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur
    • Brown J., Esnouf R.M., Jones M.A., Linnell J., Harlos K., Hassan A.B., and Jones E.Y. Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur. EMBO J. 21 (2002) 1054-1062
    • (2002) EMBO J. , vol.21 , pp. 1054-1062
    • Brown, J.1    Esnouf, R.M.2    Jones, M.A.3    Linnell, J.4    Harlos, K.5    Hassan, A.B.6    Jones, E.Y.7
  • 84
    • 33745537075 scopus 로고    scopus 로고
    • Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues
    • Zaccheo O.J., Prince S.N., Miller D.M., Williams C., Kemp C.F., Brown J., Jones E.Y., Catto L.E., Crump M.P., and Hassan A.B. Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues. J. Mol. Biol. 359 (2006) 403-421
    • (2006) J. Mol. Biol. , vol.359 , pp. 403-421
    • Zaccheo, O.J.1    Prince, S.N.2    Miller, D.M.3    Williams, C.4    Kemp, C.F.5    Brown, J.6    Jones, E.Y.7    Catto, L.E.8    Crump, M.P.9    Hassan, A.B.10
  • 85
    • 0037033019 scopus 로고    scopus 로고
    • Localization of the carbohydrate recognition sites of the insulin-like growth factor II/mannose 6-phosphate receptor to domains 3 and 9 of the extracytoplasmic region
    • Hancock M.K., Yammani R.D., and Dahms N.M. Localization of the carbohydrate recognition sites of the insulin-like growth factor II/mannose 6-phosphate receptor to domains 3 and 9 of the extracytoplasmic region. J. Biol. Chem. 277 (2002) 47205-47212
    • (2002) J. Biol. Chem. , vol.277 , pp. 47205-47212
    • Hancock, M.K.1    Yammani, R.D.2    Dahms, N.M.3
  • 86
    • 4644360229 scopus 로고    scopus 로고
    • Identification of a low affinity mannose 6-phosphate-binding site in domain 5 of the cation-independent mannose 6-phosphate receptor
    • Reddy S.T., Chai W.G., Childs R.A., Page J.D., Feizi T., and Dahms N.M. Identification of a low affinity mannose 6-phosphate-binding site in domain 5 of the cation-independent mannose 6-phosphate receptor. J. Biol. Chem. 279 (2004) 38658-38667
    • (2004) J. Biol. Chem. , vol.279 , pp. 38658-38667
    • Reddy, S.T.1    Chai, W.G.2    Childs, R.A.3    Page, J.D.4    Feizi, T.5    Dahms, N.M.6
  • 87
    • 0037192762 scopus 로고    scopus 로고
    • Identification of residues essential for carbohydrate recognition by the insulin-like growth factor II/mannose 6-phosphate receptor
    • Hancock M.K., Haskins D.J., Sun G.J., and Dahms N.M. Identification of residues essential for carbohydrate recognition by the insulin-like growth factor II/mannose 6-phosphate receptor. J. Biol. Chem. 277 (2002) 11255-11264
    • (2002) J. Biol. Chem. , vol.277 , pp. 11255-11264
    • Hancock, M.K.1    Haskins, D.J.2    Sun, G.J.3    Dahms, N.M.4
  • 88
    • 0027471426 scopus 로고
    • The bovine mannose 6-phosphate/insulin-like growth factor II receptor. The role of arginine residues in mannose 6-phosphate binding
    • Dahms N.M., Rose P.A., Molkentin J.D., Zhang Y., and Brzycki M.A. The bovine mannose 6-phosphate/insulin-like growth factor II receptor. The role of arginine residues in mannose 6-phosphate binding. J. Biol. Chem. 268 (1993) 5457-5463
    • (1993) J. Biol. Chem. , vol.268 , pp. 5457-5463
    • Dahms, N.M.1    Rose, P.A.2    Molkentin, J.D.3    Zhang, Y.4    Brzycki, M.A.5
  • 89
    • 2942558373 scopus 로고    scopus 로고
    • Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor
    • Olson L.J., Yammani R.D., Dahms N.M., and Kim J.J. Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor. EMBO J. 23 (2004) 2019-2028
    • (2004) EMBO J. , vol.23 , pp. 2019-2028
    • Olson, L.J.1    Yammani, R.D.2    Dahms, N.M.3    Kim, J.J.4
  • 90
    • 0033199917 scopus 로고    scopus 로고
    • Altered ligand binding by insulin-like growth factor II/mannose 6-phosphate receptors bearing missense mutations in human cancers
    • Devi G.R., De Souza A.T., Byrd J.C., Jirtle R.L., and MacDonald R.G. Altered ligand binding by insulin-like growth factor II/mannose 6-phosphate receptors bearing missense mutations in human cancers. Cancer Res. 59 (1999) 4314-4319
    • (1999) Cancer Res. , vol.59 , pp. 4314-4319
    • Devi, G.R.1    De Souza, A.T.2    Byrd, J.C.3    Jirtle, R.L.4    MacDonald, R.G.5
  • 91
    • 0033588086 scopus 로고    scopus 로고
    • Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations
    • Byrd J.C., Devi G.R., De Souza A.T., Jirtle R.L., and MacDonald R.G. Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations. J. Biol. Chem. 274 (1999) 24408-24416
    • (1999) J. Biol. Chem. , vol.274 , pp. 24408-24416
    • Byrd, J.C.1    Devi, G.R.2    De Souza, A.T.3    Jirtle, R.L.4    MacDonald, R.G.5
  • 92
    • 0025328862 scopus 로고
    • Regulation of mannose 6-phosphate/insulin-like growth factor II receptor distribution by activators and inhibitors of protein kinase C
    • Braulke T., Tippmer S., Chao H.J., and von Figura K. Regulation of mannose 6-phosphate/insulin-like growth factor II receptor distribution by activators and inhibitors of protein kinase C. Eur. J. Biochem. 189 (1990) 609-616
    • (1990) Eur. J. Biochem. , vol.189 , pp. 609-616
    • Braulke, T.1    Tippmer, S.2    Chao, H.J.3    von Figura, K.4
  • 93
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: biological actions
    • Jones J.I., and Clemmons D.R. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16 (1995) 3-34
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 94
    • 0025007360 scopus 로고
    • Distinctive regulation of the functional linkage between the human cation-independent mannose 6-phosphate receptor and GTP-binding proteins by insulin-like growth factor II and mannose 6-phosphate
    • Murayama Y., Okamoto T., Ogata E., Asano T., Iiri T., Katada T., Ui M., Grubb J.H., Sly W.S., and Nishimoto I. Distinctive regulation of the functional linkage between the human cation-independent mannose 6-phosphate receptor and GTP-binding proteins by insulin-like growth factor II and mannose 6-phosphate. J. Biol. Chem. 265 (1990) 17456-17462
    • (1990) J. Biol. Chem. , vol.265 , pp. 17456-17462
    • Murayama, Y.1    Okamoto, T.2    Ogata, E.3    Asano, T.4    Iiri, T.5    Katada, T.6    Ui, M.7    Grubb, J.H.8    Sly, W.S.9    Nishimoto, I.10
  • 95
    • 0033989981 scopus 로고    scopus 로고
    • Soluble insulin-like growth factor II/mannose 6-phosphate receptor inhibits DNA synthesis in insulin-like growth factor II sensitive cells
    • Scott C.D., and Weiss J. Soluble insulin-like growth factor II/mannose 6-phosphate receptor inhibits DNA synthesis in insulin-like growth factor II sensitive cells. J. Cell. Physiol. 182 (2000) 62-68
    • (2000) J. Cell. Physiol. , vol.182 , pp. 62-68
    • Scott, C.D.1    Weiss, J.2
  • 96
    • 0142117228 scopus 로고    scopus 로고
    • Increased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor in breast cancer cells alters tumorigenic properties in vitro and in vivo
    • Lee J.S., Weiss J., Martin J.L., and Scott C.D. Increased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor in breast cancer cells alters tumorigenic properties in vitro and in vivo. Int. J. Cancer 107 (2003) 564-570
    • (2003) Int. J. Cancer , vol.107 , pp. 564-570
    • Lee, J.S.1    Weiss, J.2    Martin, J.L.3    Scott, C.D.4
  • 97
    • 34548856208 scopus 로고    scopus 로고
    • The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells
    • El-Shewy H.M., Lee M.H., Obeid L.M., Jaffa A.A., and Luttrell L.M. The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells. J. Biol. Chem. 282 (2007) 26150-26157
    • (2007) J. Biol. Chem. , vol.282 , pp. 26150-26157
    • El-Shewy, H.M.1    Lee, M.H.2    Obeid, L.M.3    Jaffa, A.A.4    Luttrell, L.M.5
  • 99
    • 36849049303 scopus 로고    scopus 로고
    • Mannose 6-phosphate receptor targeting and its applications in human diseases
    • Gary-Bobo M., Nirdé P., Jeanjean A., Morère A., and Garcia M. Mannose 6-phosphate receptor targeting and its applications in human diseases. Curr. Med. Chem. 14 (2007) 2945-2953
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2945-2953
    • Gary-Bobo, M.1    Nirdé, P.2    Jeanjean, A.3    Morère, A.4    Garcia, M.5


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