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Volumn 11, Issue 1, 1997, Pages 60-67

Imprinted genes in liver carcinogenesis

Author keywords

genomic imprinting; IGF2; M6P IGF2R; tumor suppressor gene

Indexed keywords

GROWTH FACTOR; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR;

EID: 0031049935     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.11.1.9034167     Document Type: Review
Times cited : (92)

References (136)
  • 1
    • 0029080716 scopus 로고
    • Mechanistic and developmental aspects of genetic imprinting in mammals
    • Latham, K. E., McGrath, J., and Solter, D. (1995) Mechanistic and developmental aspects of genetic imprinting in mammals. Int. Rev. Cytol. 160, 53-98
    • (1995) Int. Rev. Cytol. , vol.160 , pp. 53-98
    • Latham, K.E.1    McGrath, J.2    Solter, D.3
  • 3
    • 0028086834 scopus 로고
    • Mechanism of genomic imprinting in mammals
    • Gold, J. D., and Pedersen, R. A. (1994) Mechanism of genomic imprinting in mammals. Curr. Top. Dev. Biol. 29, 227-280
    • (1994) Curr. Top. Dev. Biol. , vol.29 , pp. 227-280
    • Gold, J.D.1    Pedersen, R.A.2
  • 4
    • 0028286005 scopus 로고
    • DNA methylation and genomic imprinting
    • Razin, A., and Cedar, H. (1994) DNA methylation and genomic imprinting. Cell 77, 473-476
    • (1994) Cell , vol.77 , pp. 473-476
    • Razin, A.1    Cedar, H.2
  • 5
    • 0029160462 scopus 로고
    • Epigenetic regulation of gene expression: The effect of altered chromatin structure from yeast to mammals
    • Hendrich, B. D., and Huntington, F. W. (1995) Epigenetic regulation of gene expression: the effect of altered chromatin structure from yeast to mammals. Hum. Mol. Genet. 4, 1765-1777
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 1765-1777
    • Hendrich, B.D.1    Huntington, F.W.2
  • 6
    • 0027375345 scopus 로고
    • Gene imprinting during placental and embryonic development
    • De-Groot, N., and Hochberg, A. (1993) Gene imprinting during placental and embryonic development. Mol. Reprod. Dev. 36, 390-106
    • (1993) Mol. Reprod. Dev. , vol.36 , pp. 390-1106
    • De-Groot, N.1    Hochberg, A.2
  • 7
    • 0029091780 scopus 로고
    • Parental genomic imprinting
    • Deal, C. L. (1995) Parental genomic imprinting. Curr. Opin. Pediatr. 7, 445-458
    • (1995) Curr. Opin. Pediatr. , vol.7 , pp. 445-458
    • Deal, C.L.1
  • 10
    • 0028980026 scopus 로고
    • KIP2, a cyclin-dependent kinase inhibitor, in mouse
    • KIP2, a cyclin-dependent kinase inhibitor, in mouse. Nat. Genet. 11, 204-206
    • (1995) Nat. Genet. , vol.11 , pp. 204-206
    • Hatada, I.1    Mukai, T.2
  • 13
    • 0030249276 scopus 로고    scopus 로고
    • Clomerular-specific imprinting of the mouse Gsα gene: How does this relate to hormone resistance in Albright hereditary osteodystrophy?
    • Williamson, C. M., Schofield, J., Dutton, E. R., Seymour, A., Beechey, C. V., Edwards, Y. H., and Peters, J. (1996) Clomerular-specific imprinting of the mouse Gsα gene: how does this relate to hormone resistance in Albright hereditary osteodystrophy? Genomics, 36, 280-287
    • (1996) Genomics , vol.36 , pp. 280-287
    • Williamson, C.M.1    Schofield, J.2    Dutton, E.R.3    Seymour, A.4    Beechey, C.V.5    Edwards, Y.H.6    Peters, J.7
  • 16
    • 0030587572 scopus 로고    scopus 로고
    • Genomic imprinting and chromosomal localization of the human MEST gene
    • Nishita, Y., Yoshida, I., Sado, K., and Takagi, N. (1996) Genomic imprinting and chromosomal localization of the human MEST gene. Genumics 36, 539-542
    • (1996) Genumics , vol.36 , pp. 539-542
    • Nishita, Y.1    Yoshida, I.2    Sado, K.3    Takagi, N.4
  • 17
    • 0027180213 scopus 로고
    • The insulin-like growth factor type-2 receptor gene is imprinted in the mouse but not in humans
    • Kalscheuer, V. M., Mariman, E. C., Schepens, M. T., Rehder, H., and Ropers, H.-H. (1993) The insulin-like growth factor type-2 receptor gene is imprinted in the mouse but not in humans. Nat. Genet. 5, 74-78
    • (1993) Nat. Genet. , vol.5 , pp. 74-78
    • Kalscheuer, V.M.1    Mariman, E.C.2    Schepens, M.T.3    Rehder, H.4    Ropers, H.-H.5
  • 18
    • 0027749350 scopus 로고
    • Human insulin-like growth factor type I and type II receptors are not imprinted
    • Ogawa, O., McNoe, L., A., Eccles, M. R., Morison, I. M., and Reeve, A. E. (1993) Human insulin-like growth factor type I and type II receptors are not imprinted. Hum. Mol. Genet. 2, 2163-2165
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 2163-2165
    • Ogawa, O.1    McNoe, L.A.2    Eccles, M.R.3    Morison, I.M.4    Reeve, A.E.5
  • 19
    • 0027716060 scopus 로고
    • Functional polymorphism in the parental imprinting of the human IGF2R gene
    • Xu, Y., Goodyer, C. G., Deal, C., and Polychronakos, C. (1993) Functional polymorphism in the parental imprinting of the human IGF2R gene. Biochem. Biophys. Res. Commun. 197, 747-754
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 747-754
    • Xu, Y.1    Goodyer, C.G.2    Deal, C.3    Polychronakos, C.4
  • 20
    • 0021139084 scopus 로고
    • Completion of mouse embryogenesis requires both the maternal and paternal genomes
    • McGrath, J., and Solter, D. (1984) Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell 37, 179-183
    • (1984) Cell , vol.37 , pp. 179-183
    • McGrath, J.1    Solter, D.2
  • 21
    • 0021237658 scopus 로고
    • Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis
    • Surani, M. A., Barton, S. C., and Norris, M. I., (1984) Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature (London) 308, 548-550
    • (1984) Nature (London) , vol.308 , pp. 548-550
    • Surani, M.A.1    Barton, S.C.2    Norris, M.I.3
  • 22
    • 0026036288 scopus 로고
    • Genomic imprinting and the strange case of the insulin-like growth factor II receptor
    • Haig, D., and Graham, C. (1991) Genomic imprinting and the strange case of the insulin-like growth factor II receptor. Cell 64, 1015-1046
    • (1991) Cell , vol.64 , pp. 1015-1046
    • Haig, D.1    Graham, C.2
  • 23
    • 0026098090 scopus 로고
    • The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus
    • Barlow, D. P., Stöger, R., Herrmann, B. G., Saito, K., and Schweifer, N. (1991) The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature (London) 349, 84-87
    • (1991) Nature (London) , vol.349 , pp. 84-87
    • Barlow, D.P.1    Stöger, R.2    Herrmann, B.G.3    Saito, K.4    Schweifer, N.5
  • 24
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
    • DeChiara, T. M., Efstratiadis, A., and Robertson, E. J. (1990) A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature (London) 345, 78-80
    • (1990) Nature (London) , vol.345 , pp. 78-80
    • DeChiara, T.M.1    Efstratiadis, A.2    Robertson, E.J.3
  • 25
    • 0028284563 scopus 로고
    • Genomic imprinting: Mechanism and role in human pathology
    • Tycko, B. (1994) Genomic imprinting: mechanism and role in human pathology. Am. J. Pathol. 144, 431-443
    • (1994) Am. J. Pathol. , vol.144 , pp. 431-443
    • Tycko, B.1
  • 26
    • 0029074375 scopus 로고
    • Uniparental disomy and genomic imprinting as causes of human genetic disease
    • Cassidy, S. B. (1995) Uniparental disomy and genomic imprinting as causes of human genetic disease. Environ. Mol. Mutagen. 25, 13-20
    • (1995) Environ. Mol. Mutagen. , vol.25 , pp. 13-20
    • Cassidy, S.B.1
  • 27
    • 0016426316 scopus 로고
    • Parthenogenetic origin of benign ovarian teratomas
    • Linder, D., McCaw, B. K., and Hecht, F. (1975) Parthenogenetic origin of benign ovarian teratomas. N. Engl. J. Med. 292, 63-66
    • (1975) N. Engl. J. Med. , vol.292 , pp. 63-66
    • Linder, D.1    McCaw, B.K.2    Hecht, F.3
  • 30
    • 0026525423 scopus 로고
    • Possible evidence for genomic imprinting in childhood acute myeloblastic leukaemia associated with monosomy for chromosome 7
    • Katz, F., Webb, D., Gibbons, B., Reeves, B., McMahon, C., Cheselles, J., and Mitchell, C. (1992) Possible evidence for genomic imprinting in childhood acute myeloblastic leukaemia associated with monosomy for chromosome 7. Br. J. Haematol. 80, 332-336
    • (1992) Br. J. Haematol. , vol.80 , pp. 332-336
    • Katz, F.1    Webb, D.2    Gibbons, B.3    Reeves, B.4    McMahon, C.5    Cheselles, J.6    Mitchell, C.7
  • 31
    • 0024440608 scopus 로고
    • Genetic imprinting suggested by maternal heterodisomy in nondeletion Prader-Willi syndrome
    • Nicholls, R. D., Knoll, J. H. M., Butler, M. G., Karam, S., and Lalande, N. (1989) Genetic imprinting suggested by maternal heterodisomy in nondeletion Prader-Willi syndrome. Nature (London) 342, 281-285
    • (1989) Nature (London) , vol.342 , pp. 281-285
    • Nicholls, R.D.1    Knoll, J.H.M.2    Butler, M.G.3    Karam, S.4    Lalande, N.5
  • 32
    • 0027474137 scopus 로고
    • Genomic imprinting and uniparental disomy in Angelman and Prader-Willi syndromes: A review
    • Nicholls, R. D. (1993) Genomic imprinting and uniparental disomy in Angelman and Prader-Willi syndromes: a review. Am. J. Med. Genet 46, 16-25
    • (1993) Am. J. Med. Genet , vol.46 , pp. 16-25
    • Nicholls, R.D.1
  • 34
    • 0019827947 scopus 로고
    • Localization of the human insulin gene to the distal end of the short arm of chromosome 11
    • Harper, M. E., Ullrich, A., and Saunders, G. F. (1981) Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Proc. Natl. Acad. Sci. USA 78, 4458-4460
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 4458-4460
    • Harper, M.E.1    Ullrich, A.2    Saunders, G.F.3
  • 35
    • 0021211670 scopus 로고
    • Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor
    • Brissenden, J. E., Ullrich, A., and Franke, U. (1984) Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor. Nature (London) 310, 781-784
    • (1984) Nature (London) , vol.310 , pp. 781-784
    • Brissenden, J.E.1    Ullrich, A.2    Franke, U.3
  • 38
    • 0026849544 scopus 로고
    • Monoallelic expression of the human H19 gene
    • Zhang, Y., and Tycko, B. (1992) Monoallelic expression of the human H19 gene. Nat. Genet. 1, 40-44
    • (1992) Nat. Genet. , vol.1 , pp. 40-44
    • Zhang, Y.1    Tycko, B.2
  • 40
    • 0022910322 scopus 로고
    • Wiedemann-Beckwith syndrome: Presentation of clinical and cytogenetic data on 22 new cases and review of the literature
    • Pettenati, M. J., Haines, J. L., Higgins, R. R., Wapper, R. S., Palmer, C. G., and Weaver, D. D. (1986) Wiedemann-Beckwith syndrome: presentation of clinical and cytogenetic data on 22 new cases and review of the literature. Hum. Genet. 74, 143-154
    • (1986) Hum. Genet. , vol.74 , pp. 143-154
    • Pettenati, M.J.1    Haines, J.L.2    Higgins, R.R.3    Wapper, R.S.4    Palmer, C.G.5    Weaver, D.D.6
  • 42
    • 0028356544 scopus 로고
    • Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilm's tumor
    • Steenman, M. J. C., Rainier, S., Dobry, C. J., Grundy, P., Horon, I. L., and Feinberg, A. P. (1994) Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilm's tumor. Nat. Genet. 7, 433-439
    • (1994) Nat. Genet. , vol.7 , pp. 433-439
    • Steenman, M.J.C.1    Rainier, S.2    Dobry, C.J.3    Grundy, P.4    Horon, I.L.5    Feinberg, A.P.6
  • 43
    • 0028935017 scopus 로고
    • Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilm's tumor
    • Taniguchi, T., Sultan, M. J., Osamu, O., and Reeve, A. (1995) Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilm's tumor. Proc. Natl. Acad. Sci. USA 92, 2159-2163
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2159-2163
    • Taniguchi, T.1    Sultan, M.J.2    Osamu, O.3    Reeve, A.4
  • 46
    • 0027140480 scopus 로고
    • Tumor suppression by RNA from the 3′ untranslated region of alpha-tropomyosin
    • Rastmejad F., Conboy, M. J., Rando, T. A., and Blau, H. M. (1993) Tumor suppression by RNA from the 3′ untranslated region of alpha-tropomyosin. Cell 75, 1107-1118
    • (1993) Cell , vol.75 , pp. 1107-1118
    • Rastmejad, F.1    Conboy, M.J.2    Rando, T.A.3    Blau, H.M.4
  • 47
    • 0029776812 scopus 로고    scopus 로고
    • Suppression of malignancy by the 3′ untranslated regions of ribonucleotide reductase R1 and R2 messenger RNAs
    • Fan, H., Villigas, C., Huang, A., and Wright, J. A. (1996) Suppression of malignancy by the 3′ untranslated regions of ribonucleotide reductase R1 and R2 messenger RNAs. Cancer Res. 56, 4366-4369
    • (1996) Cancer Res. , vol.56 , pp. 4366-4369
    • Fan, H.1    Villigas, C.2    Huang, A.3    Wright, J.A.4
  • 48
    • 0024358929 scopus 로고
    • Signal transmission by the insulin-like growth factors
    • Czech, M. P. (1989) Signal transmission by the insulin-like growth factors. Cell 59, 235-238
    • (1989) Cell , vol.59 , pp. 235-238
    • Czech, M.P.1
  • 49
    • 0024369203 scopus 로고
    • Insulin-like growth factor II (IGF-II): A potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor
    • Osborne, C. K., Coronado, E. B., Kitten, L. J., Arteaga, C. I., Fuqua, S. A. W., Ramasharma, K., Marshall, M., and Li, C. H. (1989) Insulin-like growth factor II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor. Mol. Endocrinol. 3, 1701-1709
    • (1989) Mol. Endocrinol. , vol.3 , pp. 1701-1709
    • Osborne, C.K.1    Coronado, E.B.2    Kitten, L.J.3    Arteaga, C.I.4    Fuqua, S.A.W.5    Ramasharma, K.6    Marshall, M.7    Li, C.H.8
  • 50
    • 0002862225 scopus 로고
    • Insulin-like growth factor receptors
    • Schofield, P. N., ed, Oxford University Press, Oxford
    • Moxham, C., and Jacobs, S. (1992) Insulin-like growth factor receptors. In The Insulin-like Growth Factors (Schofield, P. N., ed) pp. 80-109, Oxford University Press, Oxford
    • (1992) The Insulin-like Growth Factors , pp. 80-109
    • Moxham, C.1    Jacobs, S.2
  • 52
    • 0001379970 scopus 로고
    • Local expression of insulin-like growth factors during tissue growth and regeneration
    • Schofield, P. N., ed, Oxford Medical Publications, Oxford
    • Jennische, E., Isgaard, J., and Isaksson, O. G. P. (1992) Local expression of insulin-like growth factors during tissue growth and regeneration. In The Insulin-Like Growth Factors: Structure and Biological Functions (Schofield, P. N., ed) pp. 221-239, Oxford Medical Publications, Oxford
    • (1992) The Insulin-Like Growth Factors: Structure and Biological Functions , pp. 221-239
    • Jennische, E.1    Isgaard, J.2    Isaksson, O.G.P.3
  • 53
    • 0002363497 scopus 로고
    • The involvement of insulin-like growth factors in embryonic and fetal development
    • Schofield, P. N., ed, Oxford Medical Publications, Oxford
    • Han, V. K. M., and Hill, D. J. (1992) The involvement of insulin-like growth factors in embryonic and fetal development. In The Insulin-Like Growth Factors: Structure and Biological Functions (Schofield, P. N., ed) pp. 178-220, Oxford Medical Publications, Oxford
    • (1992) The Insulin-Like Growth Factors: Structure and Biological Functions , pp. 178-220
    • Han, V.K.M.1    Hill, D.J.2
  • 54
    • 0024355048 scopus 로고
    • Insulin-like growth factors I and II. peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations
    • Daughaday, W. H., and Rotwein, P. (1989) Insulin-like growth factors I and II. peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocrinol. Rev. 10, 68-91
    • (1989) Endocrinol. Rev. , vol.10 , pp. 68-91
    • Daughaday, W.H.1    Rotwein, P.2
  • 55
    • 0025700681 scopus 로고
    • Insulin-like growth factors I and II
    • Humbel, R. E. (1990) Insulin-like growth factors I and II. Eur. J. Biochem. 190, 445-462
    • (1990) Eur. J. Biochem. , vol.190 , pp. 445-462
    • Humbel, R.E.1
  • 56
    • 0027945263 scopus 로고
    • Promoter-specific imprinting of the human insulin-like growth factor-II gene
    • Vu, T. H., and Hoffman, A. R. (1994) Promoter-specific imprinting of the human insulin-like growth factor-II gene. Nature (London) 371, 714-177
    • (1994) Nature (London) , vol.371 , pp. 714-1177
    • Vu, T.H.1    Hoffman, A.R.2
  • 57
    • 0028006662 scopus 로고
    • Parental imprinting and the IGF2 gene
    • Ekstrom, T. J. (1994) Parental imprinting and the IGF2 gene. Horm. Res. 42, 176-181
    • (1994) Horm. Res. , vol.42 , pp. 176-181
    • Ekstrom, T.J.1
  • 60
    • 0026714984 scopus 로고
    • Interference of the IGF system as a strategy to inhibit breast cancer growth
    • Arteaga, C. L. (1992) Interference of the IGF system as a strategy to inhibit breast cancer growth. Breast Cancer Res. Treat. 22, 101-106
    • (1992) Breast Cancer Res. Treat. , vol.22 , pp. 101-106
    • Arteaga, C.L.1
  • 61
    • 0024246997 scopus 로고
    • Insulin-like growth factor II mRNA expression in human breast cancer
    • Yee, D., Cullen, K. J., Paik, S., Perdue, J. F., Hampton, B., and Schwartz, A. (1988) Insulin-like growth factor II mRNA expression in human breast cancer. Cancer Res. 48, 6691-6696
    • (1988) Cancer Res. , vol.48 , pp. 6691-6696
    • Yee, D.1    Cullen, K.J.2    Paik, S.3    Perdue, J.F.4    Hampton, B.5    Schwartz, A.6
  • 62
    • 0026649393 scopus 로고
    • Insulin-like growth factor II in two human colon-carcinoma cell lines: Gene structure and expression, and protein secretion
    • Lambert, S., Carlisi, A., Collette, J., Franchimont, P., and Gol-Winkler, R. (1992) Insulin-like growth factor II in two human colon-carcinoma cell lines: gene structure and expression, and protein secretion. Int. J. Cancer 52, 404-408
    • (1992) Int. J. Cancer , vol.52 , pp. 404-408
    • Lambert, S.1    Carlisi, A.2    Collette, J.3    Franchimont, P.4    Gol-Winkler, R.5
  • 63
    • 0026538194 scopus 로고
    • Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor α
    • Lahm, H., Suardet, L., Laurent, P. L., Fischer, J. R., Ceyhan, A., Givel, J.-C., and Odartchenko, N. (1992) Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor α. Br. J. Cancer 65, 341-346
    • (1992) Br. J. Cancer , vol.65 , pp. 341-346
    • Lahm, H.1    Suardet, L.2    Laurent, P.L.3    Fischer, J.R.4    Ceyhan, A.5    Givel, J.-C.6    Odartchenko, N.7
  • 64
    • 0025864072 scopus 로고
    • Tumor IGF-II content in a patient with a colon adenocarcinoma correlates with abnormal expression of the gene
    • Lambert, S., Collette, J., Gillis, J., Franchimont, R., Desaive, C., and Gol-Winkler, R. (1991) Tumor IGF-II content in a patient with a colon adenocarcinoma correlates with abnormal expression of the gene. Int. J. Cancer 48, 826-830
    • (1991) Int. J. Cancer , vol.48 , pp. 826-830
    • Lambert, S.1    Collette, J.2    Gillis, J.3    Franchimont, R.4    Desaive, C.5    Gol-Winkler, R.6
  • 65
    • 0025005049 scopus 로고
    • Abnormal expression and structural modification of the insulin-like growth-factor-11 gene in human colorectal tumors
    • Lambert, S., Vivario, J., Boniver, J., and Gol-Winkler, R. (1990) Abnormal expression and structural modification of the insulin-like growth-factor-11 gene in human colorectal tumors. Int. J. Cancer 46, 405-410
    • (1990) Int. J. Cancer , vol.46 , pp. 405-410
    • Lambert, S.1    Vivario, J.2    Boniver, J.3    Gol-Winkler, R.4
  • 68
    • 0028880017 scopus 로고
    • Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)
    • Bates, P., Fisher, R., Ward, A., Richardson, L., Hill, D. J., and Graham, C. F. (1995) Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II). Br. J. Cancer 72, 1189-1193
    • (1995) Br. J. Cancer , vol.72 , pp. 1189-1193
    • Bates, P.1    Fisher, R.2    Ward, A.3    Richardson, L.4    Hill, D.J.5    Graham, C.F.6
  • 69
    • 0028318189 scopus 로고
    • Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice
    • Rogler, C. E., Yang, D., Rossetti, L., Donohoe, J., Alt, E., Chang, C. J., Rosenfeld, R., Neely, K., and Hintz, R. (1994) Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. J. Biol. Chem. 269, 13779-13784
    • (1994) J. Biol. Chem. , vol.269 , pp. 13779-13784
    • Rogler, C.E.1    Yang, D.2    Rossetti, L.3    Donohoe, J.4    Alt, E.5    Chang, C.J.6    Rosenfeld, R.7    Neely, K.8    Hintz, R.9
  • 70
    • 0025341727 scopus 로고
    • TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of lhe mammary gland and pancreas
    • Jhappan, C., Stahle, C., Harkins, R. N., Fausto, N., Smith, G. H., and Merlino, G. T. (1990) TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of lhe mammary gland and pancreas. Cell 61, 1137-1146
    • (1990) Cell , vol.61 , pp. 1137-1146
    • Jhappan, C.1    Stahle, C.2    Harkins, R.N.3    Fausto, N.4    Smith, G.H.5    Merlino, G.T.6
  • 71
    • 0028970950 scopus 로고
    • Transforming growth factor-α promotes mammary tumongenesis through selective survival and growth of secretory epithelial cells
    • Smith, G. H., Sharp, R., Kordon, E. C., Jhappan, C., and Merlino, G. (1995) Transforming growth factor-α promotes mammary tumongenesis through selective survival and growth of secretory epithelial cells. Am. J. Pathol. 147, 1081-1096
    • (1995) Am. J. Pathol. , vol.147 , pp. 1081-1096
    • Smith, G.H.1    Sharp, R.2    Kordon, E.C.3    Jhappan, C.4    Merlino, G.5
  • 72
    • 0028824490 scopus 로고
    • Insulin-like growth factors: The unrecognised oncogenes
    • Westley, B. R., and May, F. E. B. (1995) Insulin-like growth factors: the unrecognised oncogenes. Br. J. Cancer 72, 1065-1066
    • (1995) Br. J. Cancer , vol.72 , pp. 1065-1066
    • Westley, B.R.1    May, F.E.B.2
  • 75
    • 0028229910 scopus 로고
    • Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma
    • Zhan, S., Shapiro, D. N., and Helman, L. J. (1994) Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J. Clin. Invest. 94, 445-448
    • (1994) J. Clin. Invest. , vol.94 , pp. 445-448
    • Zhan, S.1    Shapiro, D.N.2    Helman, L.J.3
  • 77
    • 0028343231 scopus 로고
    • Altered imprinting in lung cancer
    • Suzuki, H., Veda, R., and Takahashi, T. (1994) Altered imprinting in lung cancer. Nat. Genet. 6, 332-333
    • (1994) Nat. Genet. , vol.6 , pp. 332-333
    • Suzuki, H.1    Veda, R.2    Takahashi, T.3
  • 78
    • 0029039059 scopus 로고
    • Insulin-like growth factor II in uterine smooth-muscle tumors: Maintenance of genomic imprinting in leiomyomata and loss of imprinting in leiomyosarcomata
    • Vu, T. H., Yballe, C., Boonyanit, S., and Hoffman, A. R. (1995) Insulin-like growth factor II in uterine smooth-muscle tumors: maintenance of genomic imprinting in leiomyomata and loss of imprinting in leiomyosarcomata. J. Clin. Endocrinol. Metab. 80, 1670-1676
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 1670-1676
    • Vu, T.H.1    Yballe, C.2    Boonyanit, S.3    Hoffman, A.R.4
  • 79
    • 1842385004 scopus 로고    scopus 로고
    • Loss of imprinting of H19 and IGF2 genes associated with overexpression and hypomethylation of H19 in testicular germ cell tumors
    • Barrois, M., Theodore, C., Court, B., Perrin, J. L., and Riou, C. (1996) Loss of imprinting of H19 and IGF2 genes associated with overexpression and hypomethylation of H19 in testicular germ cell tumors. Proc. Am. Assoc. Cancer Res. 37, 598
    • (1996) Proc. Am. Assoc. Cancer Res. , vol.37 , pp. 598
    • Barrois, M.1    Theodore, C.2    Court, B.3    Perrin, J.L.4    Riou, C.5
  • 81
    • 0027491152 scopus 로고
    • Maintenance of genomic imprinting at the IGF2 locus in hepatoblastnma
    • Davies, S. M. (1993) Maintenance of genomic imprinting at the IGF2 locus in hepatoblastnma. Cancer Res. 53, 4781-4783
    • (1993) Cancer Res. , vol.53 , pp. 4781-4783
    • Davies, S.M.1
  • 82
    • 0028920031 scopus 로고
    • Loss of imprinting in hepatoblastoma
    • Rainier S., Dobry, C. J., and Feinberg, A. P. (1995) Loss of imprinting in hepatoblastoma. Cancer Res. 55, 1836-1838
    • (1995) Cancer Res. , vol.55 , pp. 1836-1838
    • Rainier, S.1    Dobry, C.J.2    Feinberg, A.P.3
  • 83
    • 0029122489 scopus 로고
    • Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: Uncoupling of IGF2 and H19 imprinting
    • Li, K., Adam, G., Cui, H., Sandstedt, B., Ohlsson, R., and Ekstrom, T. J. (1995) Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: uncoupling of IGF2 and H19 imprinting. Oncogene 11, 221-229
    • (1995) Oncogene , vol.11 , pp. 221-229
    • Li, K.1    Adam, G.2    Cui, H.3    Sandstedt, B.4    Ohlsson, R.5    Ekstrom, T.J.6
  • 86
    • 0026637316 scopus 로고
    • Structure and function of the mannose 6-phosphate/insulin-like growth factor II receptors
    • Kornfeld, S. (1992) Structure and function of the mannose 6-phosphate/insulin-like growth factor II receptors. Annu. Rev. Biochem. 61, 307-330
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 307-330
    • Kornfeld, S.1
  • 88
    • 0024514387 scopus 로고
    • Serum form of the rat insulin-like growth factor II/mannose 6-phosphate receptor is truncated in the carboxyl-terminal domain
    • MacDonald, R. C., Tepper, M. A., Clairmont, C. B., Perregaux, S. B., and Czech, M. P. (1989) Serum form of the rat insulin-like growth factor II/mannose 6-phosphate receptor is truncated in the carboxyl-terminal domain. J. Biol. Chem. 264, 3256-3261
    • (1989) J. Biol. Chem. , vol.264 , pp. 3256-3261
    • MacDonald, R.C.1    Tepper, M.A.2    Clairmont, C.B.3    Perregaux, S.B.4    Czech, M.P.5
  • 89
    • 0030054287 scopus 로고    scopus 로고
    • Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognition
    • Dahms, N. M. (1996) Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognition. Biochem. Soc. Trans. 24, 136-141
    • (1996) Biochem. Soc. Trans. , vol.24 , pp. 136-141
    • Dahms, N.M.1
  • 91
    • 0028788172 scopus 로고
    • In vivo coupling of insulin-like growth factor II/mannose 6-phosphate receptor to heteromeric G-proteins
    • Ikezu, T., Okamoto, T., Giambarella, U., Yokota, T., and Nishimoto, I. (1995) In vivo coupling of insulin-like growth factor II/mannose 6-phosphate receptor to heteromeric G-proteins. J. Biol. Chem. 270, 29224-29228
    • (1995) J. Biol. Chem. , vol.270 , pp. 29224-29228
    • Ikezu, T.1    Okamoto, T.2    Giambarella, U.3    Yokota, T.4    Nishimoto, I.5
  • 92
    • 0028861822 scopus 로고
    • Mannose 6-phosphate/insulin-like growth factor II receptor fails to interact with G-proteins
    • Korner, C., Nurnberg, B., Uhde, M., and Braulke, T. (1995) Mannose 6-phosphate/insulin-like growth factor II receptor fails to interact with G-proteins. J. Biol. Chem. 270, 287-295
    • (1995) J. Biol. Chem. , vol.270 , pp. 287-295
    • Korner, C.1    Nurnberg, B.2    Uhde, M.3    Braulke, T.4
  • 93
    • 0026757062 scopus 로고
    • The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-11 receptor has two signals for lysosomal enzyme sorting in the Golgi
    • Johnson, K. F., and Kornfeld, S. (1992) The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-11 receptor has two signals for lysosomal enzyme sorting in the Golgi. J. Cell Biol. 119, 249-257
    • (1992) J. Cell Biol. , vol.119 , pp. 249-257
    • Johnson, K.F.1    Kornfeld, S.2
  • 94
    • 0027379702 scopus 로고
    • Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial mis-sorting of multiple lysosomal enzymes
    • Ludwig, T., Ovitt, C. E., Bauer, I., Hollinshead, M., Remmler, J., Lobel, P., Ruther, U., and Hoflack, B. (1993) Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial mis-sorting of multiple lysosomal enzymes. EMBO J. 12, 5225-5235
    • (1993) EMBO J. , vol.12 , pp. 5225-5235
    • Ludwig, T.1    Ovitt, C.E.2    Bauer, I.3    Hollinshead, M.4    Remmler, J.5    Lobel, P.6    Ruther, U.7    Hoflack, B.8
  • 95
    • 0023710423 scopus 로고
    • Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta-1 precursor
    • Purchio, A. F., Cooper, J. A., Brunner, A. M., Lioubin, M. N., Gentry, L. E., Kovacina, K. S., Roth, R. A., and Marquardt, H. (1988) Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta-1 precursor. J. Biol. Chem. 263, 14211-14215
    • (1988) J. Biol. Chem. , vol.263 , pp. 14211-14215
    • Purchio, A.F.1    Cooper, J.A.2    Brunner, A.M.3    Lioubin, M.N.4    Gentry, L.E.5    Kovacina, K.S.6    Roth, R.A.7    Marquardt, H.8
  • 96
    • 0024592869 scopus 로고
    • Interactions of recombinant and platelet transforming growth factor-β1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor
    • Kovacina, K. S., Steele-Perkins, G., Purchio, A. F., Lioubin, M., Miyazono, K., Heldin, C.-H., and Roth, R. A. (1989) Interactions of recombinant and platelet transforming growth factor-β1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor. Biochem. Biophys. Res. Commun. 160, 393-403
    • (1989) Biochem. Biophys. Res. Commun. , vol.160 , pp. 393-403
    • Kovacina, K.S.1    Steele-Perkins, G.2    Purchio, A.F.3    Lioubin, M.4    Miyazono, K.5    Heldin, C.-H.6    Roth, R.A.7
  • 97
    • 0026059613 scopus 로고
    • Cellular activation of latent transforming growth factor β requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor
    • Dennis, P. A., and Rifkin, D. B. (1991) Cellular activation of latent transforming growth factor β requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc. Natl. Acad. Sci. USA 88, 580-584
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 580-584
    • Dennis, P.A.1    Rifkin, D.B.2
  • 98
    • 0025989562 scopus 로고
    • Expression cloning and characterization of the TGF-β type III receptor
    • Wang, X.-F., Lin, H. Y., Ng-Eaton, E., Downward, J., Lodish, H. F., and Weinberg, R. A. (1991) Expression cloning and characterization of the TGF-β type III receptor. Cell 67, 797-805
    • (1991) Cell , vol.67 , pp. 797-805
    • Wang, X.-F.1    Lin, H.Y.2    Ng-Eaton, E.3    Downward, J.4    Lodish, H.F.5    Weinberg, R.A.6
  • 99
    • 0025987832 scopus 로고
    • Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system
    • Lopez-Cassillas, F., Cheifetz, S., Doody, J., Andres, J. L., Lane, W. S., and Massagué, J. (1991) Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system. Cell 67, 785-795
    • (1991) Cell , vol.67 , pp. 785-795
    • Lopez-Cassillas, F.1    Cheifetz, S.2    Doody, J.3    Andres, J.L.4    Lane, W.S.5    Massagué, J.6
  • 101
    • 0026537831 scopus 로고
    • Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase
    • Lin, H. Y., Wang, X.-F., Hg-Eaton, E., Weinberg, R. A., and Lodish, H. F. (1992) Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 68, 775-785
    • (1992) Cell , vol.68 , pp. 775-785
    • Lin, H.Y.1    Wang, X.-F.2    Hg-Eaton, E.3    Weinberg, R.A.4    Lodish, H.F.5
  • 103
    • 0026750213 scopus 로고
    • Receptors for the TGF-β family
    • Massagué, J. (1992) Receptors for the TGF-β family. Cell 69, 1067-1070
    • (1992) Cell , vol.69 , pp. 1067-1070
    • Massagué, J.1
  • 104
    • 0030048263 scopus 로고    scopus 로고
    • Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells
    • Kim, Y. L. Ahn, H.-J., Zelner, D. J., Shaw, J. W., Sensibar, J. A., Kim, J.-H., Kato, M., and Lee, C. (1996) Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells. Cancer Res. 56, 44-48
    • (1996) Cancer Res. , vol.56 , pp. 44-48
    • Kim, Y.L.1    Ahn, H.-J.2    Zelner, D.J.3    Shaw, J.W.4    Sensibar, J.A.5    Kim, J.-H.6    Kato, M.7    Lee, C.8
  • 106
    • 0029131403 scopus 로고
    • Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
    • Wang, J., Sun, L., Myeroff, L., Wang, X., Gentry, L. E., Yang, J., Liang, J., Zborowska, E., Markowitz, S., Willson, J. K. V., and Brattain, M. G. (1995) Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J. Biol. Chem. 270, 22044-22049
    • (1995) J. Biol. Chem. , vol.270 , pp. 22044-22049
    • Wang, J.1    Sun, L.2    Myeroff, L.3    Wang, X.4    Gentry, L.E.5    Yang, J.6    Liang, J.7    Zborowska, E.8    Markowitz, S.9    Willson, J.K.V.10    Brattain, M.G.11
  • 108
    • 0027978109 scopus 로고
    • Regulation of mannose 6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital
    • Jirtle, R. L., Hankins, G. R., Reisenbichler, H., and Boyer, I. J. (1994) Regulation of mannose 6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital. Carcinogenesis 15, 1473-1478
    • (1994) Carcinogenesis , vol.15 , pp. 1473-1478
    • Jirtle, R.L.1    Hankins, G.R.2    Reisenbichler, H.3    Boyer, I.J.4
  • 109
    • 0027199916 scopus 로고
    • Increased mannose 6-phosphate/insulin-like growth factor II receptor and TGF-β1 levels during monoterpene-induced regression of mammary tumors
    • Jirtle, R. L., Haag, J. D., Ariazi, E. A., and Gould, M. N. (1993) Increased mannose 6-phosphate/insulin-like growth factor II receptor and TGF-β1 levels during monoterpene-induced regression of mammary tumors. Cancer Res. 53, 3849-3852
    • (1993) Cancer Res. , vol.53 , pp. 3849-3852
    • Jirtle, R.L.1    Haag, J.D.2    Ariazi, E.A.3    Gould, M.N.4
  • 110
    • 0028928294 scopus 로고
    • Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol
    • Mills, J. J., Chari, R. S., Boyer, I. J., Gould, M. N., and Jirtle, R. L. (1995) Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol. Cancer Res. 55, 979-983
    • (1995) Cancer Res. , vol.55 , pp. 979-983
    • Mills, J.J.1    Chari, R.S.2    Boyer, I.J.3    Gould, M.N.4    Jirtle, R.L.5
  • 111
    • 0029100622 scopus 로고
    • Transforming growth factor beta receptors and mannose 6-phosphate/insulin-like growth factor II receptor expression in human hepatocellular carcinomas
    • Sue, S. R., Chari, R. S., Kong, F.-M., Mills, J. J., Fine, R. L., Jirtle, R. L., and Meyers, W. C. (1995) Transforming growth factor beta receptors and mannose 6-phosphate/insulin-like growth factor II receptor expression in human hepatocellular carcinomas. Ann. Surg. 222, 171-178
    • (1995) Ann. Surg. , vol.222 , pp. 171-178
    • Sue, S.R.1    Chari, R.S.2    Kong, F.-M.3    Mills, J.J.4    Fine, R.L.5    Jirtle, R.L.6    Meyers, W.C.7
  • 112
    • 0026335851 scopus 로고
    • Loss of constitutional heterozygosity in human cancer
    • Lasko, D., Cavenee, W., and Nordenskkjöld, M. (1991) Loss of constitutional heterozygosity in human cancer. Annu. Rev. Genet. 25, 281-314
    • (1991) Annu. Rev. Genet. , vol.25 , pp. 281-314
    • Lasko, D.1    Cavenee, W.2    Nordenskkjöld, M.3
  • 113
    • 0024097574 scopus 로고
    • Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-indepemlent mannose 6-phosphate receptor in man and mouse
    • Laureys, G., Barton, D. F., Ullrich, A., and Francke, U. (1988) Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-indepemlent mannose 6-phosphate receptor in man and mouse. Genomics 3, 224-229
    • (1988) Genomics , vol.3 , pp. 224-229
    • Laureys, G.1    Barton, D.F.2    Ullrich, A.3    Francke, U.4
  • 114
    • 0029031943 scopus 로고
    • Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors
    • De Souza, A. T., Hankins, G. R., Washington, M. K., Fine, R. L., Orton, T. C., and Jirtle, R. L. (1995) Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors. Oncogene 10, 1725-1729
    • (1995) Oncogene , vol.10 , pp. 1725-1729
    • De Souza, A.T.1    Hankins, G.R.2    Washington, M.K.3    Fine, R.L.4    Orton, T.C.5    Jirtle, R.L.6
  • 115
    • 0028804071 scopus 로고
    • M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
    • De Souza, A. T., Hankins, G. R., Washington, M. K., Orton, T. C., and Jirtle, R. L. (1995) M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nat. Genet. 11, 447-449
    • (1995) Nat. Genet. , vol.11 , pp. 447-449
    • De Souza, A.T.1    Hankins, G.R.2    Washington, M.K.3    Orton, T.C.4    Jirtle, R.L.5
  • 116
    • 0006343339 scopus 로고    scopus 로고
    • Mannose 6-phosphate/insulin-like growth factor-II receptor: A tumor suppressor gene in human liver cancer associated with viral hepatitis and cirrhosis
    • Yamada, T., De Souza, A. T., Finkelstein, S., Reddy, R., and Jirtle, R. L. (1996) Mannose 6-phosphate/insulin-like growth factor-II receptor: a tumor suppressor gene in human liver cancer associated with viral hepatitis and cirrhosis. Hepatology 24, 358A
    • (1996) Hepatology , vol.24
    • Yamada, T.1    De Souza, A.T.2    Finkelstein, S.3    Reddy, R.4    Jirtle, R.L.5
  • 117
    • 0025166061 scopus 로고
    • Characterization of chromosomal abnormalities in human breast cancer: A comparison of 30 paradiploid cases with few chromosome changes
    • Dutrillaux, B., Gerbault-Suereau, M., and Zafrani, B. (1990) Characterization of chromosomal abnormalities in human breast cancer: a comparison of 30 paradiploid cases with few chromosome changes. Cancer Genet. Cytogenet. 49, 203-217
    • (1990) Cancer Genet. Cytogenet. , vol.49 , pp. 203-217
    • Dutrillaux, B.1    Gerbault-Suereau, M.2    Zafrani, B.3
  • 118
    • 0025458633 scopus 로고
    • Chromosomal abnormalities in human breast cancer
    • Mars, W. M., and Saunders, G. F. (1990) Chromosomal abnormalities in human breast cancer. Cancer Metastasis Rev. 9, 35-43
    • (1990) Cancer Metastasis Rev. , vol.9 , pp. 35-43
    • Mars, W.M.1    Saunders, G.F.2
  • 119
  • 120
    • 0025321563 scopus 로고
    • Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas
    • Lee, J. H., Kavanagh, J. J., Wildrick, D. M., Wharton, J. T., and Blick, M. (1990) Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas. Cancer Res. 50, 2724-2728
    • (1990) Cancer Res. , vol.50 , pp. 2724-2728
    • Lee, J.H.1    Kavanagh, J.J.2    Wildrick, D.M.3    Wharton, J.T.4    Blick, M.5
  • 121
    • 0026699258 scopus 로고
    • Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers
    • Saito, S., Saito, H., Koi, S., Sagae, S., Kudo, R., Saito, J., Noda, K., and Nakamura, Y. (1992) Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers. Cancer Res. 52, 5815-5817
    • (1992) Cancer Res. , vol.52 , pp. 5815-5817
    • Saito, S.1    Saito, H.2    Koi, S.3    Sagae, S.4    Kudo, R.5    Saito, J.6    Noda, K.7    Nakamura, Y.8
  • 122
    • 0027408255 scopus 로고
    • Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma
    • Foulkes, W. D., Ragoussis, J., Stamp, G. W., Allan, G. J., and Trowsdale, J. (1993) Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma. Br. J. Cancer 67, 551-559
    • (1993) Br. J. Cancer , vol.67 , pp. 551-559
    • Foulkes, W.D.1    Ragoussis, J.2    Stamp, G.W.3    Allan, G.J.4    Trowsdale, J.5
  • 123
    • 0026049238 scopus 로고
    • Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma
    • Millikin, D., Meese, F., Vogelstein, B., Wilkowski, C., and Trent, J. (1991) Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma. Cancer Res. 51, 5449-5453
    • (1991) Cancer Res. , vol.51 , pp. 5449-5453
    • Millikin, D.1    Meese, F.2    Vogelstein, B.3    Wilkowski, C.4    Trent, J.5
  • 127
    • 0027999284 scopus 로고
    • Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/M6pr gene
    • Wang, Z.-Q., Fung, M. R., Barlow, D. P., and Wagner, E. F. (1994) Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/M6pr gene. Nature (London) 372, 464-467
    • (1994) Nature (London) , vol.372 , pp. 464-467
    • Wang, Z.-Q.1    Fung, M.R.2    Barlow, D.P.3    Wagner, E.F.4
  • 128
    • 0027270870 scopus 로고
    • Rescue of the T-associated maternal effect in mice carrying null mutations in Igf-2 and Igf2r, two reciprocally imprinted genes
    • Filson, A. J., Louvi, A., Efstratiadis, A., and Robertson, E. J. (1993) Rescue of the T-associated maternal effect in mice carrying null mutations in Igf-2 and Igf2r, two reciprocally imprinted genes. Development 118, 731-736
    • (1993) Development , vol.118 , pp. 731-736
    • Filson, A.J.1    Louvi, A.2    Efstratiadis, A.3    Robertson, E.J.4
  • 129
    • 0027400888 scopus 로고
    • Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal
    • Stöger, R., Kubicka, P., Liu, C.-G., Kafri, T., Razin, A., Cedar, H., and Barlow, D. P. (1993) Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 73, 61-71
    • (1993) Cell , vol.73 , pp. 61-71
    • Stöger, R.1    Kubicka, P.2    Liu, C.-G.3    Kafri, T.4    Razin, A.5    Cedar, H.6    Barlow, D.P.7
  • 130
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
    • Liu, J.-P., Baker, J., Perkins, A. S., Robertson, E. J., and Efstratiadis, A. (1993) Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75, 59-72
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.-P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 131
    • 0027018063 scopus 로고
    • Maternal imprinting of mouse Snrpn gene and conserved linkage homology with the human Prader-Willi syndrome region
    • Leff, S. E., Brannan, C. I., Reed, M. L., Ozcelik, T., Francke, U., Copeland, N. G., and Jenkins, N. A. (1992) Maternal imprinting of mouse Snrpn gene and conserved linkage homology with the human Prader-Willi syndrome region. Nat. Genet. 4, 259-264
    • (1992) Nat. Genet. , vol.4 , pp. 259-264
    • Leff, S.E.1    Brannan, C.I.2    Reed, M.L.3    Ozcelik, T.4    Francke, U.5    Copeland, N.G.6    Jenkins, N.A.7
  • 133
    • 0027378582 scopus 로고
    • Role of DNA methylation in genomic imprinting
    • Li, E., Beard, C., and Jaenisch, R. (1993) Role of DNA methylation in genomic imprinting. Nature (London) 366, 362-365
    • (1993) Nature (London) , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 135
    • 0030156684 scopus 로고    scopus 로고
    • Vital factors in liver cancer
    • Rumbsby, P. C. (1996) Vital factors in liver cancer. Hum. Exp. Toxicol. 15, 539-540
    • (1996) Hum. Exp. Toxicol. , vol.15 , pp. 539-540
    • Rumbsby, P.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.