Microsatellite instability and mismatch repair target gene mutations in cell lines and xenografts of prostate cancer

Prostate

Volumn 66, Issue 6, 2006, Pages 660-666

  Sun, Xiaodong ^a   Chen, Ceshi ^a   Vessella, Robert L ^b   Dong, Jin Tang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

BAX; Microsatellite instability; Mismatch repair; Prostate cancer; TGFBR2

Indexed keywords

PROTEIN BAX; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ARTICLE; BAX GENE; CANCER CELL CULTURE; CARCINOGENESIS; CELL DEATH; CELL PROLIFERATION; FRAMESHIFT MUTATION; GEL ELECTROPHORESIS; GENE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IGFR2 GENE; MICROSATELLITE INSTABILITY; MICROSATELLITE MARKER; MISMATCH REPAIR; MONONUCLEOTIDE REPEAT; MSH3 GENE; MSH6 GENE; NUCLEOTIDE REPEAT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE CANCER; TGFBR2 GENE; TUMOR XENOGRAFT;

ANIMALS; BASE PAIR MISMATCH; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; DNA PRIMERS; HUMANS; MALE; MICROSATELLITE REPEATS; MUTATION; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HETEROLOGOUS;

EID: 33645933898     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20390     Document Type: Article

References (45)

1. Edelmann L, Edelmann W. Loss of DNA mismatch repair function and cancer predisposition in the mouse: Animal models for human hereditary nonpolyposis colorectal cancer. Am J Med Genet C Semin Med Genet 2004;129:91-99.
2. Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993;363:558-561.
3. Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-819.
4. Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-1038.
5. Bronner CE, Baker SM, Morrison PT, Warren G, Smith LG, Lescoe MK, Kane M, Earabino C, Lipford J, Lindblom A, Tannergård P, Bollag RJ, Godwin AR, Ward DC, Nordenskjøld M, Fishel R, Kolodner R, Liskay RM. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994;368:258-261.
6. Scott RJ, McPhillips M, Meldrum CJ, Fitzgerald PE, Adams K, Spigelman AD, du Sart D, Tucker K, Kirk J. Hereditary nonpolyposis colorectal cancer in 95 families: Differences and similarities between mutation-positive and mutation-negative kindreds. Am J Hum Genet 2001;68:118-127 Epub 2000 Dec 7.
7. Polato F, Broggini M. Microsatellite instability and genetic alterations in ovarian cancer. Minerva Ginecol 2003;55:129-138.
8. Vassileva V, Millar A, Briollais L, Chapman W, Bapat B. Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability. Cancer Res 2002;62:4095-4099.
9. Perucho M. Cancer of the microsatellite mutator phenotype. Biol Chem 1996;377:675-684.
10. Fink D, Aebi S, Howell SB. The role of DNA mismatch repair in drug resistance. Clin Cancer Res 1998;4:1-6.
11. Li HR, Shagisultanova EI, Yamashita K, Piao Z, Perucho M, Malkhosyan SR. Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin. Cancer Res 2004;64:4760-4767.
12. Bhattacharyya N, Tao J, Klein EA, Banerjee S. Alterations of transforming growth factor beta receptor II, insulin growth factor receptor II genes in microsatellite unstable prostate carcinomas. Oncol Rep 2004;11:231-236.
13. Colombo P, Patriarca C, Alfano RM, Cassani B, Ceva Grimaldi G, Roncalli M, Bosari S, Coggi G, Campo B, Gould VE. Molecular disorders in transitional versus peripheral zone prostate adenocarcinoma. Int J Cancer 2001;94:383-389.
14. Dahiya R, Lee C, McCarville J, Hu W, Kaur G, Deng G. High frequency of genetic instability of microsatellites in human prostatic adenocarcinoma. Int J Cancer 1997;72:762-767.
15. Egawa S, Uchida T, Suyama K, Wang C, Ohori M, Irie S, Iwamura M, Koshiba K. Genomic instability of microsatellite repeats in prostate cancer: Relationship to clinicopathological variables. Cancer Res 1995;55:2418-2421.
16. Uchida T, Wada C, Wang C, Ishida H, Egawa S, Yokoyama E, Ohtani H, Koshiba K. Microsatellite instability in prostate cancer. Oncogene 1995;10:1019-1022.
17. Gao X, Wu N, Grignon D, Zacharek A, Liu H, Salkowski A, Li G, Sakr W, Sarkar F, Porter AT, Chen YQ, Honn KV. High frequency of mutator phenotype in human prostatic adenocarcinoma. Oncogene 1994;9:2999-3003.
18. Suzuki H, Komiya A, Aida S, Akimoto S, Shiraishi T, Yatani R, Igarashi T, Shimazaki J. Microsatellite instability and other molecular abnormalities in human prostate cancer. Jpn J Cancer Res 1995;86:956-961.
19. Watanabe M, Imai H, Shiraishi T, Shimazaki J, Kotake T, Yatani R. Microsatellite instability in human prostate cancer. Br J Cancer 1995;72:562-564.
20. Watanabe M, Imai H, Kato H, Shiraishi T, Ushijima T, Nagao M, Yatani R. Microsatellite instability in latent prostate cancers. Int J Cancer 1996;69:394-397.
21. Cunningham JM, Shan A, Wick MJ, McDonnell SK, Schaid DJ, Tester DJ, Qian J, Takahashi S, Jenkins RB, Bostwick DG, Thibodeau SN. Allelic imbalance and microsatellite instability in prostatic adenocarcinoma. Cancer Res 1996;56:4475-4482.
22. Zhou XP, Hoang JM, Li YJ, Seruca R, Carneiro F, Sobrinho-Simoes M, Lothe RA, Gleeson CM, Russell SE, Muzeau F, Flejou JF, Hoang-Xuan K, Lidereau R, Thomas G, Hamelin R. Determination of the replication error phenotype in human rumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites. Genes Chromosomes Cancer 1998;21:101-107.
23. Ahman AK, Jonsson BA, Damber JE, Bergh A, Emanuelsson M, Gronberg H. Low frequency of allelic imbalance at the prostate cancer susceptibility loci HPC1 and 1p36 in Swedish men with hereditary prostate cancer. Genes Chromosomes Cancer 2000;29:292-296.
24. Terrell RB, Wille AH, Cheville JC, Nysruen AM, Cohen MB, Sheffield VC. Microsatellite instability in adenocarcinoma of the prostate. Am J Pathol 1995;147:799-805.
25. Cho PA, Amon MA, Arnaout AA, Aziz RA, Bell D, Norman RW, Gupta R, Nassar BA. Stability of the Bax (G)8 microsatellite in localized prostatic adenocarcinoma. Can J Urol 1999;6:853-858.
26. Rohrbach H, Haas CJ, Baretton GB, Hirschmann A, Diebold J, Behrendt RP, Lohrs U. Microsatellite instability and loss of heterozygosity in prostatic carcinomas: Comparison of primary rumors, and of corresponding recurrences after androgen-deprivation therapy and lymph-node metastases. Prostate 1999;40:20-27.
27. Suzuki H, Freije D, Nusskern DR, Okami K, Cairns P, Sidransky D, Isaacs WB, Bova GS. Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues. Cancer Res 1998;58:204-209.
28. Tsujimoto Y, Takakuwa T, Takayama H, Nishimura K, Okuyama A, Aozasa K, Nonomura N. In situ shortening of CAG repeat length within the androgen receptor gene in prostatic cancer and its possible precursors. Prostate 2004;58:283-290.
29. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN, Srivastava S. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-5257.
30. Liu B, Parsons RE, Hamilton SR, Petersen GM, Lynch HT, Watson P, Markowitz S, Willson JK, Green J, de la Chapelle A, Kinzler KW, Vogelstein B. hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds. Cancer Res 1994;54:4590-4594.
31. Parsons R, Myeroff LL, Liu B, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. Cancer Res 1995;55:5548-5550.
32. Malkhosyan S, Rampino N, Yamamoto H, Perucho M. Frame-shift mutator mutations. Nature 1996;382:499-500.
33. Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed JC, Perucho M. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 1997;275:967-969.
34. Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, Lutterbaugh J, Fan RS, Zborowska E, Kinzler KW, Vogelstein B, Brattain M, Willson JKV. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 1995;268:1336-1338.
35. Souza RF, Appel R, Yin J, Wang S, Smolinski KN, Abraham JM, Zou TT, Shi YQ, Lei J, Cottrell J, Cymes K, Biden K, Simms L, Leggett B, Lynch PM, Frazier M, Powell SM, Harpaz N, Sugimura H, Young J, Meltzer SJ. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat Genet 1996;14:255-257.
36. Chen C, Bhalala HV, Vessella RL, Dong JT. KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer. Prostate 2003;55:81-88.
37. Soravia C, van der Klift H, Brundler MA, Blouin JL, Wijnen J, Hutter P, Fodde R, Delozier-Blanchet C. Prostate cancer is part of the hereditary non-polyposis colorectal cancer (HNPCC) tumor spectrum. Am J Med Genet A 2003;121:159-162.
38. van Bokhoven A, Varella-Garcia M, Korch C, Johannes WU, Smith EE, Miller HL, Nordeen SK, Miller GJ, Lucia MS. Molecular characterization of human prostate carcinoma cell lines. Prostate 2003;57:205-225.
39. Chen Y, Wang J, Fraig MM, Metcalf J, Turner WR, Bissada NK, Watson DK, Schweinfest CW. Defects of DNA mismatch repair in human prostate cancer. Cancer Res 2001;61:4112-4121.
40. Leach FS, Velasco A, Hsieh JT, Sagalowsky AI, McConnell JD. The mismatch repair gene hMSH2 is mutated in the prostate cancer cell line LNCaP. J Urol 2000;164:1830-1833.
41. Yeh CC, Lee C, Dahiya R. DNA mismatch repair enzyme activity and gene expression in prostate cancer. Biochem Biophys Res Commun 2001;285:409-413.
42. Boyer JC, Umar A, Risinger JI, Lipford JR, Kane M, Yin S, Barrett JC, Kolodner RD, Kunkel TA. Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res 1995;55:6063-6070.
43. Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:609-619.
44. Massague J, Blain SW, Lo RS. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 2000;103:295-309.
45. Hailing KC, Harper J, Moskaluk CA, Thibodeau SN, Petroni GR, Yustein AS, Tosi P, Minacci C, Roviello F, Piva P, Hamilton SR, Jackson CE, Powell SM. Origin of microsatellite instability in gastric cancer. Am J Pathol 1999;155:205-211.