Killer cell immunoglobulin-like receptor expression induction on neonatal CD8+ T cells in vitro and following congenital infection with Trypanosoma cruzi

Immunology

Volumn 129, Issue 3, 2010, Pages 418-426

  Hermann, Emmanuel ^a,e,f,g   Berthe, Aurélie ^a   Truyens, Carine ^a   Alonso Vega, Cristina ^b   Parrado, Rudy ^b   Torrico, Faustino ^b   Carlier, Yves ^a   Braud, Véronique M ^c,d  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Centro Universitario de Medicina Tropical   (Bolivia)

^c CNRS   (France)

^d UNIVERSITÉ CÔTE D'AZUR   (France)

^e UNIV LILLE   (France)

^f INSERM   (France)

^g INSTITUT PASTEUR DE LILLE   (France)

Author keywords

DNA methylation; Interleukin 2; Killer cell immunoglobulin like receptors; T cell receptors; Trypanosoma cruzi

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA; GAMMA INTERFERON; INTERLEUKIN 2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR;

ARTICLE; CD8+ T LYMPHOCYTE; CHAGAS DISEASE; CONGENITAL INFECTION; CONTROLLED STUDY; DNA METHYLATION; ENZYME REGULATION; EPIGENETICS; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; NEWBORN; NEWBORN PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRYPANOSOMA CRUZI; UMBILICAL CORD BLOOD;

EID: 75949097207     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03194.x     Document Type: Article

References (44)

1. Parham P. MHC class I molecules and KIRs in human history, health and survival. Nat Rev Immunol 2005 5 : 201 214.
2. Shiroishi M, Tsumoto K, Amano K et al. Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci USA 2003 100 : 8856 8861.
3. Braud VM, Allan DS, O'Callaghan CA et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998 391 : 795 799.
4. Braud VM, Aldemir H, Breart B, Ferlin WG. Expression of CD94-NKG2A inhibitory receptor is restricted to a subset of CD8+ T cells. Trends Immunol 2003 24 : 162 164.
5. Vivier E, Anfossi N. Inhibitory NK-cell receptors on T cells: witness of the past, actors of the future. Nat Rev Immunol 2004 4 : 190 198.
6. Poszepczynska-Guigne E, Schiavon V, D'Incan M et al. CD158k/KIR3DL2 is a new phenotypic marker of Sezary cells: relevance for the diagnosis and follow-up of Sezary syndrome. J Invest Dermatol 2004 122 : 820 823.
7. Jabri B, Selby JM, Negulescu H et al. TCR specificity dictates CD94/NKG2A expression by human CTL. Immunity 2002 17 : 487 499.
8. Mingari MC, Ponte M, Bertone S et al. HLA class I-specific inhibitory receptors in human T lymphocytes: interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8+ T cells. Proc Natl Acad Sci USA 1998 95 : 1172 1177.
9. Derre L, Corvaisier M, Pandolfino MC, Diez E, Jotereau F, Gervois N. Expression of CD94/NKG2-A on human T lymphocytes is induced by IL-12: implications for adoptive immunotherapy. J Immunol 2002 168 : 4864 4870.
10. Bertone S, Schiavetti F, Bellomo R et al. Transforming growth factor-beta-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes. Eur J Immunol 1999 29 : 23 9.
11. Vely F, Peyrat M, Couedel C et al. Regulation of inhibitory and activating killer-cell Ig-like receptor expression occurs in T cells after termination of TCR rearrangements. J Immunol 2001 166 : 2487 2494.
12. Uhrberg M, Valiante NM, Young NT, Lanier LL, Phillips JH, Parham P. The repertoire of killer cell Ig-like receptor and CD94 : NKG2A receptors in T cells: clones sharing identical alpha beta TCR rearrangement express highly diverse killer cell Ig-like receptor patterns. J Immunol 2001 166 : 3923 3932.
13. Mingari MC, Ponte M, Cantoni C et al. HLA-class I-specific inhibitory receptors in human cytolytic T lymphocytes: molecular characterization, distribution in lymphoid tissues and co-expression by individual T cells. Int Immunol 1997 9 : 485 491.
14. Warren HS, Rana PM, Rieger DT, Hewitt KA, Dahlstrom JE, Kent AL. CD8 T cells expressing killer Ig-like receptors and NKG2A are present in cord blood and express a more naive phenotype than their counterparts in adult blood. J Leukoc Biol 2006 79 : 1252 1259.
15. Santourlidis S, Trompeter HI, Weinhold S et al. Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells. J Immunol 2002 169 : 4253 4261.
16. Chan HW, Kurago ZB, Stewart CA et al. DNA methylation maintains allele-specific KIR gene expression in human natural killer cells. J Exp Med 2003 197 : 245 255.
17. Santourlidis S, Graffmann N, Christ J, Uhrberg M. Lineage-specific transition of histone signatures in the killer cell Ig-like receptor locus from hematopoietic progenitor to NK cells. J Immunol 2008 180 : 418 425.
18. Li G, Weyand CM, Goronzy JJ. Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells. J Leukoc Biol 2008 84 : 824 834.
19. Liu Y, Kuick R, Hanash S, Richardson B. DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors. Clin Immunol 2009 130 : 213 224.
20. Adkins B, Leclerc C, Marshall-Clarke S. Neonatal adaptive immunity comes of age. Nat Rev Immunol 2004 4 : 553 564.
21. Hermann E, Truyens C, Alonso-Vega C et al. Human fetuses are able to mount an adultlike CD8 T-cell response. Blood 2002 100 : 2153 2158.
22. Torrico F, Alonso-Vega C, Suarez E et al. Maternal Trypanosoma cruzi infection, pregnancy outcome, morbidity, and mortality of congenitally infected and non-infected newborns in Bolivia. Am J Trop Med Hyg 2004 70 : 201 209.
23. Hermann E, Alonso-Vega C, Berthe A et al. Human congenital infection with Trypanosoma cruzi induces phenotypic and functional modifications of cord blood NK cells. Pediatr Res 2006 60 : 38 43.
24. Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999 401 : 708 712.
25. Liao YH, Jee SH, Sheu BC et al. Increased expression of the natural killer cell inhibitory receptor CD94/NKG2A and CD158b on circulating and lesional T cells in patients with chronic plaque psoriasis. Br J Dermatol 2006 155 : 318 324.
26. Campillo JA, Martinez-Escribano JA, Moya-Quiles MR et al. Natural killer receptors on CD8 T cells and natural killer cells from different HLA-C phenotypes in melanoma patients. Clin Cancer Res 2006 12 : 4822 4831.
27. Bonorino P, Leroy V, Dufeu-Duchesne T et al. Features and distribution of CD8 T cells with human leukocyte antigen class I-specific receptor expression in chronic hepatitis C. Hepatology 2007 46 : 1375 1386.
28. van Stijn A, Rowshani AT, Yong SL et al. Human cytomegalovirus infection induces a rapid and sustained change in the expression of NK cell receptors on CD8+ T cells. J Immunol 2008 180 : 4550 4560.
29. Alter G, Rihn S, Streeck H et al. Ligand independent exhaustion of killer immunoglobulin-like receptor+ CD8+ T cells in HIV-1 infection. J Virol 2008 82 : 9668 9677.
30. Young NT, Uhrberg M, Phillips JH, Lanier LL, Parham P. Differential expression of leukocyte receptor complex-encoded Ig-like receptors correlates with the transition from effector to memory CTL. J Immunol 2001 166 : 3933 3941.
31. Ugolini S, Arpin C, Anfossi N et al. Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells. Nat Immunol 2001 2 : 430 435.
32. Ferrini S, Cambiaggi A, Meazza R et al. T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function. Eur J Immunol 1994 24 : 2294 2298.
33. Henel G, Singh K, Cui D et al. Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors. Blood 2006 107 : 4449 4457.
34. van der Veken LT, Campelo MD, van der Hoorn MA et al. Functional analysis of killer Ig-like receptor-expressing cytomegalovirus-specific CD8+ T cells. J Immunol 2009 182 : 92 101.
35. Snyder MR, Muegge LO, Offord C et al. Formation of the killer Ig-like receptor repertoire on CD4+CD28null T cells. J Immunol 2002 168 : 3839 3846.
36. Xu J, Vallejo AN, Jiang Y, Weyand CM, Goronzy JJ. Distinct transcriptional control mechanisms of killer immunoglobulin-like receptors in natural killer (NK) and in T cells. J Biol Chem 2005 280 : 24277 24285.
37. Anfossi N, Doisne JM, Peyrat MA et al. Coordinated expression of Ig-like inhibitory MHC class I receptors and acquisition of cytotoxic function in human CD8+ T cells. J Immunol 2004 173 : 7223 7229. (Pubitemid 39628158)
38. Cichocki F, Hanson RJ, Lenvik T et al. The transcription factor c-Myc enhances KIR gene transcription through direct binding to an upstream distal promoter element. Blood 2009 113 : 3245 3253.
39. Assarsson E, Kambayashi T, Sandberg JK et al. CD8+ T cells rapidly acquire NK1.1 and NK cell-associated molecules upon stimulation in vitro and in vivo. J Immunol 2000 165 : 3673 3679.
40. Schonland SO, Zimmer JK, Lopez-Benitez CM et al. Homeostatic control of T-cell generation in neonates. Blood 2003 102 : 1428 1434.
41. Cookson S, Reen D. IL-15 drives neonatal T cells to acquire CD56 and become activated effector cells. Blood 2003 102 : 2195 2197.
42. Barreto G, Schafer A, Marhold J et al. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 2007 445 : 671 675.
43. Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007 447 : 425 432.
44. Issa JP. Age-related epigenetic changes and the immune system. Clin Immunol 2003 109 : 103 108.