Increased expression of the natural killer cell inhibitory receptor CD94/NKG2A and CD158b on circulating and lesional T cells in patients with chronic plaque psoriasis

British Journal of Dermatology

Volumn 155, Issue 2, 2006, Pages 318-324

  Liao, Y H ^a   Jee, S H ^a   Sheu, B C ^a   Huang, Y L ^a   Tseng, M P ^a   Hsu, S M ^b   Tsai, T F ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

CD94 NKG2A; D158a b; Natural killer cell receptor; Psoriasis; T cell

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; CD94 ANTIGEN; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2A;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; IMMUNOPHENOTYPING; MALE; NATURAL KILLER CELL; PRIORITY JOURNAL; PSORIASIS VULGARIS; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD94; FEMALE; FLOW CYTOMETRY; HUMANS; KILLER CELLS, NATURAL; MALE; MIDDLE AGED; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY D; PSORIASIS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, KIR; RECEPTORS, KIR2DL1; RECEPTORS, KIR2DL3; SEVERITY OF ILLNESS INDEX; SKIN; T-LYMPHOCYTE SUBSETS;

EID: 33745912540     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2006.07301.x     Document Type: Article

References (36)

1. Valdimarsson H, Baker BS, Jonsdottir I et al. Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens? Immunol Today 1995; 16:145-9.
2. Gottlieb AB. Novel immunotherapies for psoriasis: clinical research delivers new hope for patients and scientific advances. J Investig Dermatol Symp Proc 2004; 9:79-83.
3. Asahina A, Akazaki S, Nakagawa H et al. Specific nucleotide sequence of HLA-C is strongly associated with psoriasis vulgaris. J Invest Dermatol 1991; 97:254-8.
4. Morreta A, Bottino C, Vitale M et al. Receptors for HLA class-I molecules in human natural killer cells. Annu Rev Immunol 1996; 14:619-48.
5. Braud VM, Allan DS, O'Callaghan CA et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998; 391:795-9.
6. Speiser DE, Valmori D, Rimoldi D et al. CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients. Eur J Immunol 1999; 29:1990-9.
7. Mingari MC, Schiavetti F, Ponte M et al. Human CD8+ T lymphocyte subsets that express HLA-class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. Proc Natl Acad Sci USA 1996; 93:12433-8.
8. Nickoloff BJ, Wrone-Smith T, Bonish B, Porcelli SA. Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: detection of T cells expressing receptors typically present on natural killer cells including CD94, CD158 and CD161. Arch Dermatol 1999; 135:546-52.
9. Nickoloff BJ, Wrone-Smith T, Huang BB, Porcelli SA. Characterization of a T cell line bearing natural killer receptors and capable of creating in a SCID mouse model system. J Dermatol Sci 2000; 24:212-25.
10. Bonish B, Jullien D, Dutronc Y et al. Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependenl IFN-γ production by NK-T cells. J Immunol 2000; 165:4076-85.
11. Gilhar A, Ullmann Y, Kerner H et al. Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes: induction of psoriasis by cells with natural killer receptors. J Invest Dermatol 2002; 119:384-91.
12. Nicholoff BJ, Wrone-Smith T. Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis. Am J Pathol 1999; 155:154-8.
13. Cameron AL, Kirby B, Fei W, Griffiths CEM. Natural killer and natural killer-T cells in psoriasis. Arch Dermatol Res 2002; 294:363-9.
14. Vissers WHPM, Arndtz CHM, Muys L et al. Memory effector (CD45RO+) and cytotoxic (CD8+) T cells appear early in the margin zone of spreading psoriatic lesions in contrast to cells expressing natural killer receptors, which appear late. Br J Dermatol 2004; 150:852-9.
15. Sheu BC, Choiu SH, Lin HH et al. Up-regulation of inhibitory natural killer receptors CD94/NKG2A with suppressed intracellular perforin expression of tumor-infiltrating CD8+ T lymphocytes in human cervical carcinoma. Cancer Res 2005; 65:2921-9.
16. Sheu BC, Lin RH, Lien HC et al. Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer. J Immunol 2001; 167:2972-8.
17. Battistini L, Borsellino G, Sawicki G et al. Phenotypic and cytokine analysis of human peripheral blood γδ T cells expressing NK cell receptors. J Immunol 1997; 159:3723-30.
18. Koreck A, Suranyi A, Szony BJ et al. CD3+ CD56+ NK T cells are significantly decreased in the peripheral blood of patients with psoriasis. Clin Exp Immunol 2002; 127:176-82.
19. Cameron AL, Kirby B, Griffiths CE. Circulating natural killer cells in psoriasis. Br J Dermatol 2003; 149:160-4.
20. Moretta L, Ciccone E, Moretta A et al. Allorecognition by NK cells: nonself or no self? Immunol Today 1992; 13:300-6.
21. Houchins JP, Lanier LL, Niemi EC et al. Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C. J Immunol 1997; 158:3603-9.
22. Lazetic S, Chang C, Houchins JP et al. Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J Immunol 1996; 157:4741-5.
23. Brooks AG, Posch PE, Scorzelli CJ et al. NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J Exp Med 1997; 185:795-800.
24. Berton S, Schiavetti F, Bellomo R et al. Transforming growth factor-beta-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes. Eur J Immunol 1999; 29:23-9.
25. Mingari MC, Ponte M, Bertone S et al. HLA class I-specific inhibitory receptors in human T lymphocytes: interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8+ T cells. Proc Natl Acad Sci USA 1998; 95:1172-7.
26. Nockowski P, Szepietowski JC, Ziarkiewicz M, Baran E. Serum concentrations of transforming growth factor beta 1 in patients with psoriasis vulgaris. Acta Dermatovenerol Croat 2004; 12:2-6.
27. Dunne J, Lynch S, O'Farrelly C et al. Selective expansion and partial activation of human NK cells and NK receptor-positive T cells by IL-2 and IL-15. J Immunol 2001; 167:3129-38.
28. Borrego F, Kabat J, Kim DK et al. Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells. Mol Immunol 2001; 38:637-60.
29. Speiser DE, Valmori D, Rimoldi D et al. In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes. J Exp Med 1999; 190:775-82.
30. Noppen C, Schaefer C, Zajac P et al. C-type lectin-like receptors in peptide-specific HLA class I-restricted cytotoxic T lymphocytes differential expression and modulation of effector functions in clones sharing identical TCR structure and epitope specificity. Eur J Immunol 1998; 28:1134-42.
31. Huard B, Karlsson L. A subpopulation of CD8+ T cells specific for melanocyte differentiation antigens expresses killer inhibitory receptor (KIR) in healthy donors: evidence for a role of KIR in the control of peripheral tolerance. Eur J Immunol 2000; 30:1665-75.
32. Jabri B, Selby JM, Negulescu H et al. TCR specificity dictates CD94/NKG2A expression by human CTL. Immunity 2002; 17:487-99.
33. Mingari MC, Moretta A, Moretta L. Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell response. Immunol Today 1998; 19:153-7.
34. Gudjonsson JE, Johnston A, Sigmundsdottir H, Valdimarsson H. Immunopathogenic mechanisms in psoriasis. Clin Exp Immunol 2004; 135:1-8.
35. Wrone-Smith T, Mitra RS, Thompson CB et al. Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared to normal skin. Am J Pathol 1997; 151:1321-9.
36. Chan WL, Pejnovic N, Liew TV et al. NKT cell subsets in infection and inflammation. Immunol Lett 2003; 85:159-63.