Quantitative cervical spinal cord 3T proton MR spectroscopy in multiple sclerosis

American Journal of Neuroradiology

Volumn 31, Issue 1, 2010, Pages 180-184

  Marliani, Anna Federica ^a   Clementi, V ^b   Riccioli, L Albini ^a   Agati, R ^a   Carpenzano, M ^a   Salvi, F ^a   Leonardi, M ^a  

^a BELLARIA HOSPITAL   (Italy)

^b Casalecchio di Reno   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; CREATINE; INOSITOL; N ACETYLASPARTIC ACID;

ADULT; AGED; ARTICLE; CERVICAL SPINAL CORD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; PROTON NUCLEAR MAGNETIC RESONANCE;

ADULT; AGED; CERVICAL VERTEBRAE; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; PROTONS; SPINAL CORD;

EID: 75749150195     PISSN: 01956108     EISSN: None     Source Type: Journal    
DOI: 10.3174/ajnr.A1738     Document Type: Article

References (46)

1. He J, Inglese M, Li BS, et al. Relapsing-remitting multiple sclerosis: metabolic abnormality in nonenhancing lesions and normal-appearing white matter at MR imaging - initial experience. Radiology 2005;234:211-17
2. Cucurella MG, Rovira A, Río J, et al. Proton magnetic resonance spectroscopy in primary and secondary progressive multiple sclerosis. NMR Biomed 2000;13:57-63
3. Sijens PE, Mostert JP, Oudkerk M, et al. 1H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings. Eur Radiol 2006;16:489-95
4. Adalsteinsson E, Langer-Gould A, Homer RJ, et al. Gray matter N-acetyl aspartate deficits in secondary progressive but not relapsing-remitting multiple sclerosis. AJNR Am J Neuroradiol 2003;24:1941-45
5. Narayanan PA, Doyle TJ, Lai D, et al. Serial proton magnetic resonance spectroscopic imaging, contrast-enhanced magnetic resonance imaging, and quantitative lesion volumetry in multiple sclerosis. Ann Neurol 1998;43:56-71
6. Nelson F, Poonawalla AH, Hou P, et al. Improved identification of intracortical lesions in multiple sclerosis with phase-sensitive inversion recovery in combination with fast double inversion recovery MR imaging. AJNR Am J Neuroradiol 2007;28:1645-49
7. Chard DT, Griffin CM, McLean MA, et al. Brain metabolite changes in cortical grey and normal-appearing white matter in clinically early relapsing-remitting multiple sclerosis. Brain 2002;125:2342-52
8. Bozzali M, Cercignani M, Sormani MP, et al. Quantification of brain gray matter damage in different MS phenotypes by use of diffusion tensor MR imaging. AJNR Am J Neuroradiol 2002;23:985-88
9. Dehmeshki J, Chard DT, Leary SM, et al. The normal appearing grey matter in primary progressive multiple sclerosis: a magnetisation transfer imaging study. J Neurol 2003;250:67-74
10. Kapeller P, McLean MA, Griffin CM, et al. Preliminary evidence for neuronal damage in cortical grey matter and normal appearing white matter in short duration relapsing-remitting multiple sclerosis: a quantitative MR spectroscopic imaging study. J Neurol 2001;248:131-38
11. Narayanan PA. Magnetic resonance spectroscopy in the monitoring of multiple sclerosis. J Neuroimaging 2005;15:46S57S
12. Miki Y, Grossman RI, Udupa JK, et al. Relapsing-remitting multiple sclerosis: longitudinal analysis of MR images - lack of correlation between changes in T2 lesion volume and clinical findings. Radiology 1999;213:395-99
13. Zivadinov R, Leist TP. Clinical-magnetic resonance imaging correlations in multiple sclerosis. J Neuroimaging 2005;15:10S-21S
14. Brex PA, Ciccarelli O, O'Riordan JI, et al.Alongitudinal study of abnormalities on MRI and disability from multiple sclerosis. N Engl J Med 2002;346:158-64
15. Barkhof F. The clinico-pathological paradox in multiple sclerosis revisited. Curr Opin Neurol 2002;15:239-45
16. Wolinsky JS, Narayana PA, Fenstermacher MJ. Proton magnetic resonance spectroscopy in multiple sclerosis. Neurology 1990;40:1764-69
17. Inglese M, Li BS, Rusinek H, et al. Diffusely elevated cerebral choline and creatine in relapsing-remitting multiple sclerosis. Magn Reson Med 2003;50: 190-95
18. De Stefano N, Narayanan S, Francis GS, et al. Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability. Arch Neurol 2001;58:65-70
19. De Stefano N, Matthews PM, Fu L, et al. Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis: results of a longitudinal magnetic resonance spectroscopy study. Brain 1998;121:1469-77
20. Kapeller P, Brex PA, Chard D, et al. Quantitative 1H MRS imaging 14 years after presenting with a clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler 2002;8:207-10
21. Kendi AT, Tan FU, Kendi M, et al. MR spectroscopy of cervical spinal cord in patients with multiple sclerosis. Neuroradiology 2004;46:764-69
22. Blamire AM, Cader S, Lee M, et al. Axonal damage in the spinal cord of multiple sclerosis patients detected by magnetic resonance spectroscopy. Magn Reson Med 2007;58:880-85
23. Henning A, Schär M, Kollias SS, et al. Quantitative magnetic resonance spectroscopy in the entire human cervical spinal cord and beyond at 3T. Magn Reson Med 2008;59:1250-58
24. Cooke F, Blamire AM, Korlpara LP, et al. Proton spectroscopy of the motor pathway in patients with spinocerebellar ataxia (SCA). In: Proceedings of the 13th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Miami Beach, FL. May 7-13, 2005:1227
25. Dydak U, Kollias SS, Schär M, et al.MR spectroscopy in different regions of the spinal cord and in spinal cord tumors. In: Proceedings of the 13th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Miami Beach, FL. May 7-13, 2005:813
26. Ciccarelli O, Wheeler-Kingshott CA, McLean MA, et al. Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis. Brain 2007;130:2220-31
27. Marliani AF, Clementi V, Albini-Riccioli L, et al. Quantitative proton magnetic resonance spectroscopy of the human cervical spinal cord at 3 Tesla. Magn Reson Med 2007;57:160-63
28. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis. Ann Neurol 2001;50:121-27
29. Tran TK, Vigneron DB, Sailasuta N, et al. Very selective suppression pulses for clinical MRSI studies of brain and prostate cancer. Magn Reson Med 2000;43:23-33
30. Cooke FJ, Blamire AM, Manners DN, et al. Quantitative proton magnetic resonance spectroscopy of the cervical spinal cord. Magn Reson Med 2004;51: 1122-28
31. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30:672-79
32. Gomez-Anson B, MacManus DG, Parker GJM, et al. In vivo 1H-magnetic resonance spectroscopy of the spinal cord in humans. Neuroradiology 2000;42:515-17
33. Dubey P, Smith M, Bonekamp D, et al. Proton MR spectroscopic imaging of the human cervical spine at 3 Tesla. In: Proceedings of the 13th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Miami Beach, FL. May 7-13, 2005:812
34. Edden RA, Bonekamp D, Smith MA, et al. ProtonMRspectroscopic imaging of the medulla and cervical spinal cord. J Magn Reson Imaging 2007;26:1101-05
35. Bot JC, Barkhof F. Spinal-cord MRI in multiple sclerosis: conventional and nonconventional MR techniques. Neuroimaging Clin N Am 2009;19:81-99
36. Thorpe JW, Kidd D, Moseley IF, et al. Serial gadolinium-enhanced MRI of the brain and spinal cord in early relapsing-remitting multiple sclerosis. Neurology 1996;46:373-78
37. Kidd D, Thorpe JW, Kendall BE, et al. MRI dynamics of brain and spinal cord in progressive multiple sclerosis. J Neurol Neurosurg Psychiatry 1996;60:15-19
38. Bot JC, Barkhof F, Polman CH, et al. Spinal cord abnormalities in recently diagnosed MS patients: added value of spinal MRI examination. Neurology 2004;62:226-33
39. Bjartmar C, Kidd G, Mork S, et al. Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Ann Neurol 2000;48:893-901
40. Ruiz-Pena JL, Pinero P, SellersG,et al.Magneticresonance spectroscopy ofnormal appearing white matter in early relapsing-remitting multiple sclerosis: correlations between disability and spectroscopy. BMC Neurol 2004;4:8
41. Bot JC, Blezer EL, Kamphorst W, et al. The spinal cord in multiple sclerosis: relationship of high-spatial-resolution quantitative MR imaging findings to histopathologic results. Radiology 2004;233:531-40
42. Bergers E, Bot JC, De Groot CJ, et al. Axonal damage in the spinal cord of MS patients occurs largely independent of T2 MRI lesions. Neurology 2002;59:1766-71
43. Rashid W, Davies GR, Chard DT, et al. Increasing cord atrophy in early relapsing-remitting multiple sclerosis: a 3 year study. J Neurol Neurosurg Psychiatry 2006;77:51-55
44. Nijeholt G, van Walderveen MA, Castelijns JA, et al. Brain and spinal cord abnormalities in multiple sclerosis: correlation between MRI parameters, clinical subtypes and symptoms. Brain 1998;121:687-97
45. Stevenson VL, Leary SM, Losseff NA, et al. Spinal cord atrophy and disability in MS: a longitudinal study. Neurology 1998;51:234-38
46. Riccioli LA, Marliani AF, Clementi V, et al. Evolutive study of relapsing-remitting multiple sclerosis with cervical proton magnetic resonance spectroscopy: a case report. Neuroradiol J 2008;21:511-17