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Volumn 97, Issue 1, 2010, Pages 7-15

Role of the epithelial-mesenchymal transition during tumor progression;Rôle de la transition épithéliomésenchymateuse dans la progression tumorale

Author keywords

Embryogenesis; EMT; Metastatic dissemination; Tumor progression

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; SCATTER FACTOR; SMAD PROTEIN; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR TWIST; UVOMORULIN; TRANSCRIPTION FACTOR;

EID: 75749125815     PISSN: 00074551     EISSN: 17696917     Source Type: Journal    
DOI: 10.1684/bdc.2009.1025     Document Type: Article
Times cited : (10)

References (59)
  • 3
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumor progression
    • Thiery JP. Epithelial-mesenchymal transitions in tumor progression. Nat Rev Cancer 2002 ; 2 : 442-54.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 4
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
    • Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008 ; 14 : 818-29.
    • (2008) Dev Cell , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 6
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 2008 ; 68 : 3645-54.
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 7
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004 ; 117 : 927-39.
    • (2004) Cell , vol.117 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3    Ramaswamy, S.4    Itzykson, R.A.5    Come, C.6
  • 9
    • 54449085718 scopus 로고    scopus 로고
    • Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers
    • DumontN,WilsonMB, Crawford YG, Reynolds PA, SigaroudiniaM, Tlsty TD. Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proc Natl Acad Sci USA 2008 ; 105 : 14867-72.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14867-14872
    • Dumont, N.1    Wilson, M.B.2    Crawford, Y.G.3    Reynolds, P.A.4    Sigaroudinia, M.5    Tlsty, T.D.6
  • 10
    • 34249289041 scopus 로고    scopus 로고
    • SNAI1, ZEB and bHLH factors in tumor progression: An alliance against the epithelial phenotype?
    • Peinado H, Olmeda D, Cano A. SNAI1, ZEB and bHLH factors in tumor progression: an alliance against the epithelial phenotype? Nat Rev Cancer 2007 ; 7 : 415-28.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 11
    • 51449123136 scopus 로고    scopus 로고
    • Tissue deformation modulates twist expression to determine anterior midgut differentiation in drosophila embryos
    • Desprat N, Supatto W, Pouille PA, Beaurepaire E, Farge E. Tissue deformation modulates twist expression to determine anterior midgut differentiation in drosophila embryos. Dev Cell 2008 ; 15 : 470-7.
    • (2008) Dev Cell , vol.15 , pp. 470-477
    • Desprat, N.1    Supatto, W.2    Pouille, P.A.3    Beaurepaire, E.4    Farge, E.5
  • 12
    • 0041423614 scopus 로고    scopus 로고
    • Mechanical induction of twist in the drosophila foregut/ stomodeal primordium
    • Farge E. Mechanical induction of twist in the drosophila foregut/ stomodeal primordium. Curr Biol 2003 ; 13 : 1365-77.
    • (2003) Curr Biol , vol.13 , pp. 1365-1377
    • Farge, E.1
  • 13
    • 40449114805 scopus 로고    scopus 로고
    • The twist1 oncogene is a direct target of hypoxia-inducible factor-2-alpha
    • Gort EH, van HG, Verlaan I, Groot AJ, Plasterk RH, Shvarts A, et al. The twist1 oncogene is a direct target of hypoxia-inducible factor-2-alpha. Oncogene 2008 ; 27 : 1501-10.
    • (2008) Oncogene , vol.27 , pp. 1501-1510
    • Gort1    EH, V.H.2    Verlaan, I.3    Groot, A.J.4    Plasterk, R.H.5    Shvarts, A.6
  • 14
    • 33845724527 scopus 로고    scopus 로고
    • VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and SNAI1
    • Evans AJ, Russell RC, Roche O, Burry TN, Fish JE, Chow VW, et al. VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and SNAI1. Mol Cell Biol 2007 ; 27 : 157-69.
    • (2007) Mol Cell Biol , vol.27 , pp. 157-169
    • Evans, A.J.1    Russell, R.C.2    Roche, O.3    Burry, T.N.4    Fish, J.E.5    Chow, V.W.6
  • 15
    • 67651204282 scopus 로고    scopus 로고
    • Oxygen deprivation inhibits basal keratinocyte proliferation in a model of human skin and induces regio-specific changes in the distribution of epidermal adherens junction proteins, aquaporin-3, and glycogen
    • Straseski JA, Gibson AL, Thomas-Virnig CL, Len-Hoffmann BL. Oxygen deprivation inhibits basal keratinocyte proliferation in a model of human skin and induces regio-specific changes in the distribution of epidermal adherens junction proteins, aquaporin-3, and glycogen. Wound Repair Regen 2009 ; 17 : 606-16.
    • (2009) Wound Repair Regen , vol.17 , pp. 606-616
    • Straseski, J.A.1    Gibson, A.L.2    Thomas-Virnig, C.L.3    Len-Hoffmann, B.L.4
  • 16
    • 58149237893 scopus 로고    scopus 로고
    • Phosphoregulation of twist1 provides a mechanism of cell fate control
    • Firulli AB, Conway SJ. Phosphoregulation of twist1 provides a mechanism of cell fate control. Curr Med Chem 2008 ; 15 : 2641-7.
    • (2008) Curr Med Chem , vol.15 , pp. 2641-2647
    • Firulli, A.B.1    Conway, S.J.2
  • 17
    • 29244463349 scopus 로고    scopus 로고
    • Switching on-off SNAI1: LOXL2 versus GSK3-beta
    • Peinado H, Portillo F, Cano A. Switching on-off SNAI1: LOXL2 versus GSK3-beta. Cell Cycle 2005 ; 4 : 1749-52.
    • (2005) Cell Cycle , vol.4 , pp. 1749-1752
    • Peinado, H.1    Portillo, F.2    Cano, A.3
  • 19
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of SNAI1 by NF-kappaB is required for inflammationinduced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP. Stabilization of SNAI1 by NF-kappaB is required for inflammationinduced cell migration and invasion. Cancer Cell 2009 ; 15 : 416-28.
    • (2009) Cancer Cell , vol.15 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 20
  • 21
    • 33748059537 scopus 로고    scopus 로고
    • Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells
    • Ao M, Williams K, Bhowmick NA, Hayward SW. Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells. Cancer Res 2006 ; 66 : 8007-16.
    • (2006) Cancer Res , vol.66 , pp. 8007-8016
    • Ao, M.1    Williams, K.2    Bhowmick, N.A.3    Hayward, S.W.4
  • 22
    • 33748116186 scopus 로고    scopus 로고
    • A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
    • Spaderna S, Schmalhofer O, Hlubek F, Berx G, Eger A, Merkel S, et al. A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology 2006 ; 131 : 830-40.
    • (2006) Gastroenterology , vol.131 , pp. 830-840
    • Spaderna, S.1    Schmalhofer, O.2    Hlubek, F.3    Berx, G.4    Eger, A.5    Merkel, S.6
  • 23
    • 33750311251 scopus 로고    scopus 로고
    • In vivo and in vitro evidence for transforming growth factorbeta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma
    • Rees JR, Onwuegbusi BA, Save VE, Alderson D, Fitzgerald RC. In vivo and in vitro evidence for transforming growth factorbeta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma. Cancer Res 2006 ; 66 : 9583-90.
    • (2006) Cancer Res , vol.66 , pp. 9583-9590
    • Rees, J.R.1    Onwuegbusi, B.A.2    Save, V.E.3    Alderson, D.4    Fitzgerald, R.C.5
  • 25
    • 12244290974 scopus 로고    scopus 로고
    • Dedifferentiation and decreased expression of adhesion molecules, E-cadherin and ZO-1, in colorectal cancer are closely related to liver metastasis
    • Kaihara T, Kusaka T, Nishi M, Kawamata H, Imura J, Kitajima K, et al. Dedifferentiation and decreased expression of adhesion molecules, E-cadherin and ZO-1, in colorectal cancer are closely related to liver metastasis. J Exp Clin Cancer Res 2003 ; 22 : 117-23.
    • (2003) J Exp Clin Cancer Res , vol.22 , pp. 117-123
    • Kaihara, T.1    Kusaka, T.2    Nishi, M.3    Kawamata, H.4    Imura, J.5    Kitajima, K.6
  • 26
    • 0035215429 scopus 로고    scopus 로고
    • Expression of E-cadherin and lymph node metastasis in resected non-small cell lung cancer
    • Hirata T, Fukuse T, Naiki H, Wada H. Expression of E-cadherin and lymph node metastasis in resected non-small cell lung cancer. Clin Lung Cancer 2001 ; 3 : 134-40.
    • (2001) Clin Lung Cancer , vol.3 , pp. 134-140
    • Hirata, T.1    Fukuse, T.2    Naiki, H.3    Wada, H.4
  • 27
    • 0027530351 scopus 로고
    • Expression of E-cadherin cell adhesionmolecules in human breast cancer tissues and its relationship to metastasis
    • Oka H, Shiozaki H, Kobayashi K, Inoue M, Tahara H, Kobayashi T, et al. Expression of E-cadherin cell adhesionmolecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 1993 ; 53 : 1696-701.
    • (1993) Cancer Res , vol.53 , pp. 1696-1701
    • Oka, H.1    Shiozaki, H.2    Kobayashi, K.3    Inoue, M.4    Tahara, H.5    Kobayashi, T.6
  • 28
    • 22244473343 scopus 로고    scopus 로고
    • The fallacy of epithelial mesenchymal transition in neoplasia
    • Tarin D, Thompson EW, Newgreen DF. The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res 2005 ; 65 : 5996-6000.
    • (2005) Cancer Res , vol.65 , pp. 5996-6000
    • Tarin, D.1    Thompson, E.W.2    Newgreen, D.F.3
  • 29
    • 0030452985 scopus 로고    scopus 로고
    • Mesenchyme to epithelium transition during development of the mammalian kidney tubule
    • Davies JA. Mesenchyme to epithelium transition during development of the mammalian kidney tubule. Acta Anat (Basel) 1996 ; 156 : 187-201.
    • (1996) Acta Anat (Basel) , vol.156 , pp. 187-201
    • Davies, J.A.1
  • 30
    • 0033552929 scopus 로고    scopus 로고
    • WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts
    • Hosono S, Luo X, Hyink DP, Schnapp LM,Wilson PD, Burrow CR, et al. WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts. Oncogene 1999 ; 18 : 417-27.
    • (1999) Oncogene , vol.18 , pp. 417-427
    • Hosono, S.1    Luo, X.2    Hyink, D.P.3    Schnapp, L.M.4    Wilson, P.D.5    Burrow, C.R.6
  • 31
  • 33
    • 45849087087 scopus 로고    scopus 로고
    • Induction of EMT by twist proteins as a collateral effect of tumorpromoting inactivation of premature senescence
    • Ansieau S, Bastid J, Doreau A, Morel AP, Bouchet BP, Thomas C, et al. Induction of EMT by twist proteins as a collateral effect of tumorpromoting inactivation of premature senescence. Cancer Cell 2008 ; 14 : 79-89.
    • (2008) Cancer Cell , vol.14 , pp. 79-89
    • Ansieau, S.1    Bastid, J.2    Doreau, A.3    Morel, A.P.4    Bouchet, B.P.5    Thomas, C.6
  • 34
    • 33645416798 scopus 로고    scopus 로고
    • Cancer cells escape from fail safe programs in a simple twist
    • Puisieux A, Valsesia-Wittmann S. Cancer cells escape from fail safe programs in a simple twist. Bull Cancer 2006 ; 93 : 251-6.
    • (2006) Bull Cancer , vol.93 , pp. 251-256
    • Puisieux, A.1    Valsesia-Wittmann, S.2
  • 37
    • 60649089997 scopus 로고    scopus 로고
    • Cancer metastasis is accelerated through immunosuppression during SNAI1-induced EMT of cancer cells
    • Kudo-Saito C, Shirako H, Takeuchi T, Kawakami Y. Cancer metastasis is accelerated through immunosuppression during SNAI1-induced EMT of cancer cells. Cancer Cell 2009 ; 15 : 195-206.
    • (2009) Cancer Cell , vol.15 , pp. 195-206
    • Kudo-Saito, C.1    Shirako, H.2    Takeuchi, T.3    Kawakami, Y.4
  • 38
    • 48549091043 scopus 로고    scopus 로고
    • RB depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition
    • Arima Y, Inoue Y, Shibata T, Hayashi H, Nagano O, Saya H, et al. RB depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition. Cancer Res 2008 ; 68 : 5104-12.
    • (2008) Cancer Res , vol.68 , pp. 5104-5112
    • Arima, Y.1    Inoue, Y.2    Shibata, T.3    Hayashi, H.4    Nagano, O.5    Saya, H.6
  • 39
    • 38349078213 scopus 로고    scopus 로고
    • Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19ARF/p53 pathway lesions but not p16 Ink4a loss
    • Debies MT, Gestl SA, Mathers JL, Mikse OR, Leonard TL, Moody SE, et al. Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19ARF/p53 pathway lesions but not p16 Ink4a loss. J Clin Invest 2008 ; 118 : 51-63.
    • (2008) J Clin Invest , vol.118 , pp. 51-63
    • Debies, M.T.1    Gestl, S.A.2    Mathers, J.L.3    Mikse, O.R.4    Leonard, T.L.5    Moody, S.E.6
  • 40
    • 69349098834 scopus 로고    scopus 로고
    • Stem cells: The promises and perils of p53
    • Krizhanovsky V, Lowe SW. Stem cells: the promises and perils of p53. Nature 2009 ; 460 : 1085-6.
    • (2009) Nature , vol.460 , pp. 1085-1086
    • Krizhanovsky, V.1    Lowe, S.W.2
  • 42
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008 ; 133 : 704-15.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 44
    • 33845963177 scopus 로고    scopus 로고
    • Stem cells and cancer: The last frontier?
    • Larsen CJ. Stem cells and cancer: the last frontier? Bull Cancer 2006 ; 93 : 1083-4.
    • (2006) Bull Cancer , vol.93 , pp. 1083-1084
    • Larsen, C.J.1
  • 45
    • 25444495269 scopus 로고    scopus 로고
    • Opinion: Migrating cancer stem cells -an integrated concept of malignant tumor progression
    • Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells -an integrated concept of malignant tumor progression. Nat Rev Cancer 2005 ; 5 : 744-9.
    • (2005) Nat Rev Cancer , vol.5 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 46
    • 69549131213 scopus 로고    scopus 로고
    • Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
    • Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci USA 2009 ; 106 : 13820-5.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13820-13825
    • Creighton, C.J.1    Li, X.2    Landis, M.3    Dixon, J.M.4    Neumeister, V.M.5    Sjolund, A.6
  • 47
    • 0842286741 scopus 로고    scopus 로고
    • Identification of a novel function of twist, a bHLH protein, in the development of acquired taxol resistance in human cancer cells
    • Wang X, Ling MT, Guan XY, Tsao SW, Cheung HW, Lee DT, et al. Identification of a novel function of twist, a bHLH protein, in the development of acquired taxol resistance in human cancer cells. Oncogene 2004 ; 23 : 474-82.
    • (2004) Oncogene , vol.23 , pp. 474-482
    • Wang, X.1    Ling, M.T.2    Guan, X.Y.3    Tsao, S.W.4    Cheung, H.W.5    Lee, D.T.6
  • 48
    • 35148825636 scopus 로고    scopus 로고
    • Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
    • Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A, et al. Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. Int J Oncol 2007 ; 31 : 277-83.
    • (2007) Int J Oncol , vol.31 , pp. 277-283
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3    Yamashita, M.4    Ino, K.5    Nawa, A.6
  • 49
    • 65549141305 scopus 로고    scopus 로고
    • Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway
    • Wang Z, Li Y, Kong D, Banerjee S, Ahmad A, Azmi AS, et al. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res 2009 ; 69 : 2400-7.
    • (2009) Cancer Res , vol.69 , pp. 2400-2407
    • Wang, Z.1    Li, Y.2    Kong, D.3    Banerjee, S.4    Ahmad, A.5    Azmi, A.S.6
  • 50
    • 33847327128 scopus 로고    scopus 로고
    • Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines
    • Yang AD, Fan F, Camp ER, Van BG, Liu W, Somcio R, et al. Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. Clin Cancer Res 2006 ; 12 : 4147-53.
    • (2006) Clin Cancer Res , vol.12 , pp. 4147-4153
    • Yang, A.D.1    Fan, F.2    Camp, E.R.3    Van, B.G.4    Liu, W.5    Somcio, R.6
  • 52
    • 36949002825 scopus 로고    scopus 로고
    • Role of p14ARF in twist-mediated senescence in prostate epithelial cells
    • Kwok WK, Ling MT, Yuen HF, Wong YC, Wang X. Role of p14ARF in twist-mediated senescence in prostate epithelial cells. Carcinogenesis 2007 ; 28 : 2467-75.
    • (2007) Carcinogenesis , vol.28 , pp. 2467-2475
    • Kwok, W.K.1    Ling, M.T.2    Yuen, H.F.3    Wong, Y.C.4    Wang, X.5
  • 53
    • 52149095811 scopus 로고    scopus 로고
    • Knockdown of SNAI1, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway
    • Zhuo W, Wang Y, Zhuo X, Zhang Y, Ao X, Chen Z. Knockdown of SNAI1, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway. Lung Cancer 2008 ; 62 : 8-14.
    • (2008) Lung Cancer , vol.62 , pp. 8-14
    • Zhuo, W.1    Wang, Y.2    Zhuo, X.3    Zhang, Y.4    Ao, X.5    Chen, Z.6
  • 56
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumor clearance is triggered by p53 restoration in murine liver carcinomas
    • Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, et al. Senescence and tumor clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007 ; 445 : 656-60.
    • (2007) Nature , vol.445 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3    Dickins, R.A.4    Hernando, E.5    Krizhanovsky, V.6
  • 58
    • 69549117133 scopus 로고    scopus 로고
    • Targeted inhibition of SNAI1 family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate
    • Harney AS, Lee J, Manus LM, Wang P, Ballweg DM, LaBonne C, et al. Targeted inhibition of SNAI1 family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate. Proc Natl Acad Sci USA 2009 ; 106 : 13667-72.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13667-13672
    • Harney, A.S.1    Lee, J.2    Manus, L.M.3    Wang, P.4    Ballweg, D.M.5    LaBonne, C.6
  • 59
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by highthroughput screening
    • Gupta PB,Onder TT, JiangG, Tao K, Kuperwasser C,Weinberg RA, et al. Identification of selective inhibitors of cancer stem cells by highthroughput screening. Cell 2009 ; 138 : 645-59.
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3    Tao, K.4    Kuperwasser, C.5    Weinberg, R.A.6


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