메뉴 건너뛰기




Volumn 666, Issue , 2009, Pages 88-94

Immunomodulatory activity and therapeutic potential of the filarial nematode secreted product, ES-62

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ES 62; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C ALPHA; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; ES 62 PROTEIN, ACANTHOCHEILONEMA VITEAE; ES-62 PROTEIN, ACANTHOCHEILONEMA VITEAE; HELMINTH PROTEIN; IMMUNOLOGIC FACTOR;

EID: 75649130420     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-1601-3_7     Document Type: Article
Times cited : (27)

References (50)
  • 1
    • 0024417450 scopus 로고
    • Hay fever, hygiene, and household size
    • Strachan DP. Hay fever, hygiene and household size. BMJ 1989; 299(6710):1259-1260. (Pubitemid 19280051)
    • (1989) British Medical Journal , vol.299 , Issue.6710 , pp. 1259-1260
    • Strachan, D.P.1
  • 2
    • 0037013751 scopus 로고    scopus 로고
    • Immunoregulation of CNS autoimmunity by helminth and mycobacterial infections
    • DOI 10.1016/S0165-2478(02)00025-1, PII S0165247802000251
    • Sewell DL, Reinke EK, Hogan LH et al. Immunoregulation of CNS autoimmunity by helminth and mycobacterial infections. Immunol Lett 2002; 82(1-2):101-110. (Pubitemid 34468041)
    • (2002) Immunology Letters , vol.82 , Issue.1-2 , pp. 101-110
    • Sewell, D.L.1    Reinke, E.K.2    Hogan, L.H.3    Sandor, M.4    Fabry, Z.5
  • 3
    • 0016741329 scopus 로고
    • Rheumatoid arthritis in a rural south african negro population
    • Beighton P, Solomon L, Valkenburg HA. Rheumatoid arthritis in a rural south african negro population. Ann Rheum Dis 1975; 34(2):136-141.
    • (1975) Ann Rheum Dis , vol.34 , Issue.2 , pp. 136-141
    • Beighton, P.1    Solomon, L.2    Valkenburg, H.A.3
  • 4
    • 18844374468 scopus 로고    scopus 로고
    • A worm's eye view of the immune system: Consequences for evolution of human autoimmune disease
    • DOI 10.1038/nri1601
    • Dunne DW, Cooke A. A worm's eye view of the immune system: consequences for evolution of human autoimmune disease. Nat Rev Immunol 2005; 5(5):420-426. (Pubitemid 40685991)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.5 , pp. 420-426
    • Dunne, D.W.1    Cooke, A.2
  • 5
    • 27144432428 scopus 로고    scopus 로고
    • Infections and allergy - Helminths, hygiene and host immune regulation
    • DOI 10.1016/j.coi.2005.09.001, PII S0952791505001536, Autoimmunity / Allergy and Hypersensitivity
    • Maizels RM. Infections and allergy - helminths, hygiene and host immune regulation. Curr Opin Immunol 2005; 17(6):656-661. (Pubitemid 41506912)
    • (2005) Current Opinion in Immunology , vol.17 , Issue.6 , pp. 656-661
    • Maizels, R.M.1
  • 6
    • 0004597189 scopus 로고    scopus 로고
    • WHO, Geneva: World Health Organisation
    • WHO. Filariasis. Geneva: World Health Organisation, 2000.
    • (2000) Filariasis
  • 8
    • 0034850181 scopus 로고    scopus 로고
    • Transmission intensity and human immune responses to lymphatic filariasis
    • DOI 10.1046/j.1365-3024.2001.00395.x
    • King CL. Transmission intensity and human immune responses to lymphatic filariasis. Parasite Immunol 2001; 23(7):363-371. (Pubitemid 32848288)
    • (2001) Parasite Immunology , vol.23 , Issue.7 , pp. 363-371
    • King, C.L.1
  • 9
    • 1642493655 scopus 로고    scopus 로고
    • Pathogenesis and host responses in human onchocerciasis: Impact of Onchocerca filariae and Wolbachia endobacteria
    • DOI 10.1016/j.micinf.2003.11.003
    • Brattig NW. Pathogenesis and host responses in human onchocerciasis: impact of onchocerca filariae and wolbachia endobacteria. Microbes Infect 2004; 6(1):113-128. (Pubitemid 38114828)
    • (2004) Microbes and Infection , vol.6 , Issue.1 , pp. 113-128
    • Brattig, N.W.1
  • 10
    • 0024746127 scopus 로고
    • Origin, kinetics of circulation and fate in vivo of the major excretory-secretory product of Acanthocheilonema viteae
    • Hamett W, Grainger M, Kapil A et al. Origin, kinetics of circulation and fate in vivo of the major excretory-secretory product of Acanthocheilonema viteae, Parasitol Today 1989; 99:229-239.
    • (1989) Parasitol Today , vol.99 , pp. 229-239
    • Harnett, W.1    Grainger, M.2    Kapil, A.3
  • 11
    • 0036668170 scopus 로고    scopus 로고
    • Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific
    • DOI 10.1017/S0031182002001920
    • Stepek G, Auchie M, Tare R et al. Expression of the filarial nematode phosphorylcholine-conraming glycoprotein, ES62, is stage specific. Parasitology 2002; 125(Pt 2):155-164. (Pubitemid 34925513)
    • (2002) Parasitology , vol.125 , Issue.2 , pp. 155-164
    • Stepek, G.1    Auchie, M.2    Tate, R.3    Watson, K.4    Russell, D.G.5    Devaney, E.6    Harnett, W.7
  • 12
    • 0348100953 scopus 로고    scopus 로고
    • Stage-specific and species-specific differences in the production of the mRNA and protein for the filarial nematode secreted product, ES-62
    • DOI 10.1017/S0031182003004220
    • Stepek G, Houston KM, Goodridge HS et al. Stage-specific and species-specific differences in the production of the mRNA and protein for the filarial nematode secreted product, ES- 62 Parasitol Today 2004; 128(Pt 1):91-98. (Pubitemid 38177810)
    • (2004) Parasitology , vol.128 , Issue.1 , pp. 91-98
    • Stepek, G.1    Houston, K.M.2    Goodridge, H.S.3    Devaney, E.4    Harnett, W.5
  • 13
    • 0037302799 scopus 로고    scopus 로고
    • Structural/functional aspects of ES-62 - A secreted immunomodulatory phosphorylcholine-containing filarial nematode glycoprotein
    • DOI 10.2174/1389203033380368
    • Harnett W; Hamett MM, Byron O. Structural/functional aspects of ES-62-a secreted irnmunomodulatory phosphorylchollne-conralning filarial nematode glycoprotein. Curr Protein Pepr Sci 2003; 4( 1):59-71. (Pubitemid 36131671)
    • (2003) Current Protein and Peptide Science , vol.4 , Issue.1 , pp. 59-71
    • Harnett, W.1    Harnett, M.M.2    Byron, O.3
  • 15
    • 0027208935 scopus 로고
    • Aminopeptidases: Towards a mechanism of action
    • Taylor A. Aminopeptidases: towards a mechanism of action. Trends in Biochemical Sciences 1993; 18(5):167-171.
    • (1993) Trends in Biochemical Sciences , vol.18 , Issue.5 , pp. 167-171
    • Taylor, A.1
  • 16
    • 0031894438 scopus 로고    scopus 로고
    • Characterization and partial purification of a leucine aminopeptidase from Fasciola hepatica
    • DOI 10.2307/3284518
    • Acosta D, Goni F, Carmona C. Characterization and partial purification of a leucine aminopeptidase from fasciola hepatica, Journal of Parasitology 1998; 84(1):1-7. (Pubitemid 28125421)
    • (1998) Journal of Parasitology , vol.84 , Issue.1 , pp. 1-7
    • Acosta, D.1    Goni, F.2    Carmona, C.3
  • 17
    • 0027137177 scopus 로고
    • Acanthocheilonema viteae: Phosphorylcholine is attached to the major excretory-secretory product via an N-linked glycan
    • DOI 10.1006/expr.1993.1113
    • Harnett W; Houston KM, Amess R et al. Acanthocheilonema viteae: phosphorylcholine is attached to the major excretory-secretory product via an N-linked glycan. Exp Parasitol 1993; 77:498-502. (Pubitemid 24011005)
    • (1993) Experimental Parasitology , vol.77 , Issue.4 , pp. 498-502
    • Harnett, W.1    Houston, K.M.2    Amess, R.3    Worms, M.J.4
  • 19
    • 0032997668 scopus 로고    scopus 로고
    • Phosphorylcholine: Friend or foe of the immune system?
    • DOI 10.1016/S0167-5699(98)01419-4, PII S0167569998014194
    • Harnetr W; Harnett MM. Phosphorylcholine: Friend or foe of the immune system? Immunology Today 1999; 20(3):125-129. (Pubitemid 29130341)
    • (1999) Immunology Today , vol.20 , Issue.3 , pp. 125-129
    • Harnett, W.1    Harnett, M.M.2
  • 20
    • 0031573557 scopus 로고    scopus 로고
    • A filarial nematode secreted product differentially modulates expression and activation of protein kinase C isoforms in B-lymphocytes
    • Deehan M, Harnert M, Harnetr W. A filarial nematode secreted product differentially modulates expression and activation of protein kinase C isoforms in B-lymphocytes. J Immunol 1997; 159(12):6105-6111. (Pubitemid 127471549)
    • (1997) Journal of Immunology , vol.159 , Issue.12 , pp. 6105-6111
    • Deehan, M.R.1    Harnett, M.M.2    Harnett, W.3
  • 21
    • 0032521026 scopus 로고    scopus 로고
    • A phosphorylcholine-containing filarial nematode-secreted product disrupts B lymphocyte activation by targeting key proliferative signaling pathways
    • Deehan MR, Frame MJ, Parkhouse RM et al. A phosphorylcholine-containing filarial nematode-secreted product disrupts B-lymphocyte activation by targeting key proliferative signaling pathways. J Immunol 1998; 160(6):2692-2699. (Pubitemid 28136720)
    • (1998) Journal of Immunology , vol.160 , Issue.6 , pp. 2692-2699
    • Deehan, M.R.1    Frame, M.J.2    Parkhouse, R.M.E.3    Seatter, S.D.4    Reid, S.D.5    Harnett, M.M.6    Harnett, W.7
  • 22
    • 0035876914 scopus 로고    scopus 로고
    • A filarial nematode-secreted phosphorylcholine-containing glycoprotein uncouples the B cell antigen receptor from extracellular signal-regulated kinase-mitogen-activated protein kinase by promoting the surface Ig-mediated recruitment of Src homology 2 domain-containing tyrosine phosphatase-1 and pac-1 mitogen-activated kinase-phosphatase
    • Deehan MR, Harnett W; Hamett MM. A filarialnematode-secreted phosphorylcholine-conramtng glycoprotein uncouples the B-cell antigen receptor from extracellular signal-regulated kinase-mitogen-activated protein kinase by promoting the surface Ig-mediated recruitment of Src homology 2 domain-containing tyrosine phosphatase-I and Pac-I mitogen-activated kinase-phosphatase. Journal of Immunology 2001; 166(12):7462-7468. (Pubitemid 32525624)
    • (2001) Journal of Immunology , vol.166 , Issue.12 , pp. 7462-7468
    • Deehan, M.R.1    Harnett, W.2    Harnett, M.M.3
  • 23
    • 0027505088 scopus 로고
    • Inhibition of murine B cell proliferation and down-regulation of protein kinase C levels by a phosphorylcholine-containing filarial excretory- secretory product
    • Harnerr W; Harnett MM. Inhibition of murine B-cell proliferation and down-regulation of protein kinase C levelsby a phosphorylcholine-conraining filarial excretory-secretory product. J Immunol 1993; 151:4829-4837. (Pubitemid 23318536)
    • (1993) Journal of Immunology , vol.151 , Issue.9 , pp. 4829-4837
    • Harnett, W.1    Harnett, M.M.2
  • 24
    • 0031744129 scopus 로고    scopus 로고
    • Induction of signalling anergy via the T-cell receptor in cultured Jurkat T cells by pre-exposure to a filarial nematode secreted product
    • Harnett MM, Deehan MR, Williams DM et al. Induction of signalling anergy via the T-cell receptor in cultured jurkat T-cells by pre-exposure to a filarial nematode secreted product. Parasite Immunology 1998; 20(11):551-563. (Pubitemid 28521705)
    • (1998) Parasite Immunology , vol.20 , Issue.11 , pp. 551-563
    • Harnett, M.M.1    Deehan, M.R.2    Williams, D.M.3    Harnett, W.4
  • 25
    • 0346095279 scopus 로고    scopus 로고
    • In vivo activation of murine peritoneal B1 cells by the filarial nematode phosphorylcholine-containing glycoprotein ES-62
    • DOI 10.1111/j.1365-3024.2003.00650.x
    • Wilson EH, Katz E, Goodridge HS et al. In vivo activation of murine peritoneal Bl cells by the filarial nematode phosphorylcholine-conraining glycoprotein ES- 62 Parasite Immunol 2003; 25(8-9):463-466. (Pubitemid 38058024)
    • (2003) Parasite Immunology , vol.25 , Issue.8-9 , pp. 463-466
    • Wilson, E.H.1    Katz, E.2    Goodridge, H.S.3    Harnett, M.M.4    Harnett, W.5
  • 26
    • 0034660408 scopus 로고    scopus 로고
    • A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells
    • Whelan M, Hamett MM, Houston KM et al.A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells.J Immunol 2000; 164(12):6453-6460. (Pubitemid 30408828)
    • (2000) Journal of Immunology , vol.164 , Issue.12 , pp. 6453-6460
    • Whelan, M.1    Harnett, M.M.2    Houston, K.M.3    Patel, V.4    Harnett, W.5    Rigley, K.P.6
  • 27
    • 0035879221 scopus 로고    scopus 로고
    • Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae
    • Goodridge HS, Wilson EH, Harnett W et al. Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae. J Immunol 2001; 167:940-945. (Pubitemid 32660851)
    • (2001) Journal of Immunology , vol.167 , Issue.2 , pp. 940-945
    • Goodridge, H.S.1    Wilson, E.H.2    Harnett, W.3    Campbell, C.C.4    Harnett, M.M.5    Liew, F.Y.6
  • 28
  • 29
    • 0033857664 scopus 로고    scopus 로고
    • Presence of phosphorylcholine on a filarial nematode protein inlluences immunoglobulin G subclass response to the molecule by an interleukin-l0- dependent mechanism
    • Houston KM, Wilson EH, Eyres L et al. Presence of phosphorylcholine on a filarial nematode protein inlluences immunoglobulin G subclass response to the molecule by an interleukin-l0-dependent mechanism. Infect Immun 2000; 68(9):5466-5468.
    • (2000) Infect Immun , vol.68 , Issue.9 , pp. 5466-5468
    • Houston, K.M.1    Wilson, E.H.2    Eyres, L.3
  • 30
    • 27144526103 scopus 로고    scopus 로고
    • ES-62, an immunomodulator secreted by filarial nematodes, suppresses clonal expansion and modifies effector function of heterologous antigen-specific T cells in vivo
    • Marshall FA, Garside P, Harnett W et al. ES-62, an immunomodulator secreted by filarial nematodes suppresses clonal expansion and skewseffector function of heterologous antigen-specific T-cells in vivo. J Immunol 2005; 175:5817-5826. (Pubitemid 41508066)
    • (2005) Journal of Immunology , vol.175 , Issue.9 , pp. 5817-5826
    • Marshall, F.A.1    Grierson, A.M.2    Garside, P.3    Harnett, W.4    Harnett, M.M.5
  • 31
    • 33847667225 scopus 로고    scopus 로고
    • The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
    • DOI 10.1111/j.1365-2249.2007.03356.x
    • Afzali B, Lombardi G, Lechler RI et al. The role ofT helper 17 (ThI7) and regulatory T-cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 2007; 148(1):32-46. (Pubitemid 46365005)
    • (2007) Clinical and Experimental Immunology , vol.148 , Issue.1 , pp. 32-46
    • Afzali, B.1    Lombardi, G.2    Lechler, R.I.3    Lord, G.M.4
  • 32
    • 38949197817 scopus 로고    scopus 로고
    • IL-17/ThI7 targeting: On the road to prevent chronic destructive arthritis?
    • Lubberts E. IL-17/ThI7 targeting: on the road to prevent chronic destructive arthritis? Cytokine 2008; 41(2):84-91.
    • (2008) Cytokine , vol.41 , Issue.2 , pp. 84-91
    • Lubberts, E.1
  • 33
    • 0346463316 scopus 로고    scopus 로고
    • Rationale for targeting interleukin 17 in the lungs
    • Linden A. Rationale for targeting interleukin 17 in the lungs. Curr Opin Investig Drugs 2003; 4( 11):1304-1312.
    • (2003) Curr Opin Investig Drugs , vol.4 , Issue.11 , pp. 1304-1312
    • Linden, A.1
  • 35
    • 0033857664 scopus 로고    scopus 로고
    • The presence ofphosphorylcholine on a filarial nematode protein inlluences the IgG subclass response to a molecule and by a mechanism dependent on IL-lO
    • Houston K, Wilson EH, EyresL et al. The presence ofphosphorylcholine on a filarial nematode protein inlluences the IgG subclass response to a molecule and by a mechanism dependent on IL-lO. Infect Immunity 2000; 68(9):5466-5468.
    • (2000) Infect Immunity , vol.68 , Issue.9 , pp. 5466-5468
    • Houston, K.1    Wilson, E.H.2    Eyres, L.3
  • 38
    • 4644356708 scopus 로고    scopus 로고
    • Subversion of immunological signalling by a filarial nematode phosphorylcholine-containing secreted product
    • DOI 10.1016/j.cellsig.2004.05.014, PII S0898656804001056
    • Goodridge HS. Deehan MR, Harnett W et al. Subversion of immunological signalling by a filarial nematode phosphorylcholine-containing secreted product. Cell Signal 2005; 17(1):11-16. (Pubitemid 39286775)
    • (2005) Cellular Signalling , vol.17 , Issue.1 , pp. 11-16
    • Goodridge, H.S.1    Deehan, M.R.2    Harnett, W.3    Harnett, M.M.4
  • 39
    • 21244485905 scopus 로고    scopus 로고
    • Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES-62
    • DOI 10.1111/j.1365-2567.2005.02167.x
    • Goodridge HS, Stepek G, Harnett W et al. Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES- 62 Immunology 2005; 115(3):296-304. (Pubitemid 40896028)
    • (2005) Immunology , vol.115 , Issue.3 , pp. 296-304
    • Goodridge, H.S.1    Stepek, G.2    Harnett, W.3    Harnett, M.M.4
  • 40
    • 0344157333 scopus 로고    scopus 로고
    • Production of T-cell cytokines at the single-cell level in patients with inllammatory arthritides: Enhanced activity in synoviallluid compared to blood
    • RonnelidJ, Berg L, Rogberg S et al. Production of T-cell cytokines at the single-cell level in patients with inllammatory arthritides: Enhanced activity in synoviallluid compared to blood. BrJ Rheumatol 1998; 37(1):7-14.
    • (1998) Br J Rheumatol , vol.37 , Issue.1 , pp. 7-14
    • Ronnelid, J.1    Berg, L.2    Rogberg, S.3
  • 41
    • 0032939156 scopus 로고    scopus 로고
    • Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
    • DOI 10.1002/1529-0131(199905)42:5<963::AID-ANR15>3.0.CO;2-E
    • Chabaud M, Durand JM. Buchs N et al. Human interleukin-17: AT-cell-derived proinllammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 1999; 42:963-970. (Pubitemid 29215007)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.5 , pp. 963-970
    • Chabaud, M.1    Durand, J.M.2    Buchs, N.3    Fossiez, F.4    Page, G.5    Frappart, L.6    Miossec, P.7
  • 42
    • 0032743708 scopus 로고    scopus 로고
    • A proinllammatory role for IL-18 in rheumatoid arthritis
    • GracieJA. Forsey RJ, Chan WL et al. A proinllammatory role for IL-18 in rheumatoid arthritis.} Clin Invest 1999; 104(10):1393-1401.
    • (1999) J Clin Invest , vol.104 , Issue.10 , pp. 1393-1401
    • Gracie, J.A.1    Forsey, R.J.2    Chan, W.L.3
  • 44
    • 0029876121 scopus 로고    scopus 로고
    • Role of cytokines in rheumatoid arthritis
    • DOI 10.1146/annurev.immunol.14.1.397
    • Feldmann M, Brennan FM. Maini RN. Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 1996; 14:397-440. (Pubitemid 26130190)
    • (1996) Annual Review of Immunology , vol.14 , pp. 397-440
    • Feldmann, M.1    Brennan, F.M.2    Maini, R.N.3
  • 45
    • 0042134781 scopus 로고    scopus 로고
    • A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62
    • McInnes IB, Leung BP, Harnett M et al. A novel therapeutic approach targeting articular inllammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62.J Immunol 2003; 171(4):2127-2133. (Pubitemid 36966497)
    • (2003) Journal of Immunology , vol.171 , Issue.4 , pp. 2127-2133
    • McInnes, I.B.1    Leung, B.P.2    Harnett, M.3    Gracie, J.A.4    Liew, F.Y.5    Harnett, W.6
  • 47
    • 0026644298 scopus 로고
    • Anti-turnor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • Williams RO, Feldmann M, Maini RN. Anti-turnor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Nacl Acad Sci USA 1992; 89(20):9784-9788.
    • (1992) Proc Nacl Acad Sci USA , vol.89 , Issue.20 , pp. 9784-9788
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 48
    • 41949119523 scopus 로고    scopus 로고
    • Failure of ES-62 to inhibit T-helper type 1 responses to other filarial nematode antigens
    • DOI 10.1111/j.1365-3024.2008.01024.x
    • Ai-Riyami L, Egan C, Bradley JE et al. Failure of ES-62 to inhibit T-helper Type 1 responses to other filarial nematode antigens. Parasite Immunol 2008; 30(5):304-308. (Pubitemid 351514547)
    • (2008) Parasite Immunology , vol.30 , Issue.5 , pp. 304-308
    • Al-Riyami, L.1    Egan, C.A.2    Bradley, J.E.3    Lustigman, S.4    Harnett, W.5
  • 49
    • 10644221237 scopus 로고    scopus 로고
    • Structure and synthesis of nematode phosphorylcholine-containing glycoconjugates
    • DOI 10.1017/S0031182004006171
    • Houston KM, Harnett w: Structure and synthesis of nematode phosphorylchollne-concaining glycoconjugates. Parasitology 2004; 129(Pt 6):655-661. (Pubitemid 39657757)
    • (2004) Parasitology , vol.129 , Issue.6 , pp. 655-661
    • Houston, K.M.1    Harnett, W.2
  • 50
    • 33645084285 scopus 로고    scopus 로고
    • Dissecting ascaris glycosphingolipids for immunornodulatory moieties - The use of synthetic structural glycosphingolipid analogues
    • Kean DE, Ohtsuka I, Saro K et al. Dissecting ascaris glycosphingolipids for immunornodulatory moieties - the use of synthetic structural glycosphingolipid analogues. Parasite Immunol 2006; 28(3):69-76.
    • (2006) Parasite Immunol , vol.28 , Issue.3 , pp. 69-76
    • Kean, D.E.1    Ohtsuka, I.2    Saro, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.