Structure and synthesis of nematode phosphorylcholine-containing glycoconjugates

Parasitology

Volumn 129, Issue 6, 2004, Pages 655-661

  Houston, K M ^a   Harnett, W ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Glycoconjugates; Nematode; Phosphorylcholine

Indexed keywords

CARBOHYDRATE; GLYCAN DERIVATIVE; GLYCOCONJUGATE; GLYCOSPHINGOLIPID; N ACETYLGLUCOSAMINE; OLIGOSACCHARIDE; PHOSPHORYLCHOLINE;

ACANTHOCHEILONEMA VITEAE; CAENORHABDITIS ELEGANS; COVALENT BOND; FILARIA; FUCOSYLATION; GOLGI COMPLEX; HOST PARASITE INTERACTION; IMMUNE RESPONSE; IMMUNOMODULATION; INTRACELLULAR TRANSPORT; LONGEVITY; MASS SPECTROMETRY; NEMATODE; NONHUMAN; ONCHOCERCA GIBSONI; ONCHOCERCA VOLVULUS; PHENOTYPE; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; REVIEW; STRUCTURE ANALYSIS; SURVIVAL;

ANIMALS; DRUG DESIGN; FILARICIDES; GLYCOCONJUGATES; HELMINTH PROTEINS; HUMANS; NEMATODA; PHOSPHORYLCHOLINE;

ACANTHOCHEILONEMA VITEAE; CAENORHABDITIS; CAENORHABDITIS ELEGANS; FILARIA; FUNGI; NEMATODA; ONCHOCERCA; ONCHOCERCA GIBSONI; ONCHOCERCA VOLVULUS;

EID: 10644221237     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0031182004006171     Document Type: Review

References (38)

1. ALLAN, D. & OBRADORS, M. J. M. (1999). Enzyme distributions in subcellular fractions of BHK cells infected with Semliki virus: evidence for major fraction of sphingomyelin synthase in the trans-golgi network. Biochimica et Biophysica Acta 1450, 277-287.
2. BISHOP, W. R. & BELL, R. M. (1988). Assembly of phospholipids into cellular membranes: biosynthesis, transmembrane movement and intracellular translocation. Annual Review of Cell Biology 4, 579-610.
3. CARMAN, G. M. & HENRY, S. A. (1989). Phospholipid biosynthesis in yeast. Annual Review of Biochemistry 58, 6635-6669.
4. CARMAN, G. M. & HENRY, S. A. (1999). Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes. Progress in Lipid Research 38, 361-399.
5. CARROLL, M. & BIRD, M. M. (1991). Glycoprotein expression in mouse cerebellum: effects of inhibitors of N-linked glycosylation. International Journal of Biochemistry 23, 1285-1291.
6. CIPOLLO, J. F., COSTELLO, C. E. & HIRSCHBERG, C. B. (2002). The fine structure of Caenorhabditis elegans N-glycans. Journal of Biological Chemistry 277, 49143-49157.
7. ELBEIN, A. D. (1987). Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains. Annual Review of Biochemistry 56, 497-534.
8. ELBEIN, A. D., TROPEA, J. E., MITCHELL, M. & KAUSHAL, G. P. (1990). Kufunensine, a potent inhibitor of the glycoprotein processing mannosidase I. Journal of Biological Chemistry 265, 15599-15605.
9. GERDT, S., DENNIS, R. D., BORGONIE, G., SCHNABEL, R. & GEYER, R. (1999). Isolation, characterization and immunolocalization of phosphorylcholine-substituted glycolipids in developmental stages of Caenorhabditis elegans. European Journal of Biochemistry 266, 952-963.
10. HARNETT, W., FRAME, M. J., NOR, Z. M., MACDONALD, M. & HOUSTON, K. M. (1994). Some preliminary data on the nature/structure of the PC-glycan of the major excretory-secretory product of Acanthocheilonema viteae (ES-62). Parasite 1, 179-181.
11. HARNETT, W., HOUSTON, K. M., AMESS, R. & WORMS, M. J. (1993). Acanthocheilonema viteae: phosphorylcholine is attached to the major excretory-secretory product via an N-linked glycan. Experimental Parasitology 77, 498-502.
12. HARNETT, W., WORMS, M. J., KAPIL, A., GRAINGER, M. & PARKHOUSE, R. M. (1989). Origin, kinetics of circulation and fate in vivo of the major excretory-secretory product of Acanthocheilonema viteae. Parasitology 99, 229-239.
13. HASLAM, S. M. & DELL, A. (2003). Hallmarks of Caenorhabditis elegans N-glycosylation: complexity and controversy. Biochimie 85, 25-32.
14. HASLAM, S. D., GEMS, D., MORRIS, H. R. & DELL, A. (2002). The glycomes of Caenorhabditis elegans and other model organisms. Biochemical Society Symposium 69, 117-134.
15. HASLAM, S. M., HOUSTON, K. M., HARNETT, W., REASON, A. J., MORRIS, H. R. & DELL, A. (1999). Structural studies of N-glycans of filarial parasites. Conservation of phosphorylcholine-substituted glycans among species and discovery of novel chito-oligomers. Journal of Biological Chemistry 274, 20953-20960.
16. HASLAM, S. M., KHOO, K. H., HOUSTON, K. M., HARNETT, W., MORRIS, H. R. & DELL, A. (1997). Characterisation of the phosphorylcholine-containing N-linked oligosaccharides in the excretory-secretory 62 kDa glycoprotein of Acanthocheilonema viteae. Molecular and Biochemical Parasitology 85, 53-66.
17. HOUSTON, K. M., CUSHLEY, W. & HARNETT, W. (1997). Studies on the site and mechanism of attachment of phosphorylcholine to a filarial nematode secreted glycoprotein. Journal of Biological Chemistry 272, 1527-1533.
18. HOUSTON, K. M. & HARNETT, W. (1996). Prevention of attachment of phosphorylcholine to a major excretory-secretory product of Acanthocheilonema viteae using tunicamycin. Journal of Parasitology 82, 320-324.
19. HOUSTON, K. M. & HARNETT, W. (1999). Mechanisms underlying the transfer of phosphorylcholine to filarial nematode glycoproteins - a possible role for choline kinase. Parasitology 118, 311-318.
20. HOUSTON, K. M., LOCHNIT, G., GEYER, R. & HARNETT, W. (2002). Investigation of the nature of potential phosphorylcholine donors for filarial nematode glycoconjugates. Molecular and Biochemical Parasitology 123, 55-66.
21. HUNZIKER, W., WHITNEY, J. A. & MELLMAN, I. (1992). Brefeldin A and the endocytic pathway. Possible implications for membrane traffic and sorting. FEBS Letters 307, 93-96.
22. KAMINSKY, R. (2003). Drug resistance in nematodes: a paper tiger or a real problem? Current Opinion in Infectious Diseases 16, 559-564.
23. LAL, R. B., PARANJAPE, R. S., BRILES, D. E., NUTMAN, T. B. & OTTESEN, E. A. (1987). Circulating parasite antigen(s) in lymphatic filariasis: use of monoclonal antibodies to phosphocholine for immunodiagnosis. Journal of Immunology 138, 3454-3460.
24. LODISH, H. F. & KONG, N. (1984). Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex. Journal of Cell Biology 98, 1720-1729.
25. LOCHNIT, G., DENNIS, R. D., ULMER, A. J. & GEYER, R. (1998). Structural elucidation and monokine-inducing activity of two biologically active zwitterionic glycosphingolipids derived from the parasitic nematode Ascaris suum. Journal of Biological Chemistry 278, 466-474.
26. MAIZELS, R. M., BURKE, J. & DENHAM, D. A. (1987). Phosphorylcholine-bearing antigens in filarial nematode parasites: analysis of somatic extracts, in-vitro secretions and infection sera from Brugia malayi and B. pahangi. Parasite Immunology 9, 49-66.
27. MIQUEL, K., PRADINES, A., TERCE, F., SELMI, S. & FAVRE, G. (1998). Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells. Jorunal of Biological Chemistry 273, 26179-26186.
28. MORELLE, W., HASLAM, S. M., MORRIS, H. R. & DELL, A. (2000a). Characterization of the N-linked glycans of adult Trichinella spiralis. Molecular and Biochemical Parasitology 109, 171-177.
29. MORELLE, W., HASLAM, S. M., OLIVIER, V., APPLETON, J. A., MORRIS, H. R. & DELL, A. (2000b). Phosphorylcholine-containing N-glycans of Trichinella spiralis: identification of multiantennary lacdiNAc structures. Glycobiology 10, 941-950.
30. NOR, Z. M., DEVANEY, E. & HARNETT, W. (1997). The use of inhibitors of N-linked glycosylation and oligosaccharide processing to produce monoclonal antibodies against non-phosphorylcholine epitopes of Brugia pahangi excretory-secretory products. Parasitology Research 83, 813-815.
31. NOR, Z. M., HOUSTON, K. M., DEVANEY, E. & HARNETT, W. (1997). Variation in the nature of attachment of phosphorylcholine to excretory-secretory products of adult Brugia pahangi. Parasitology 114, 257-262.
32. PERY, P., PETIT, A., POULAIN, J. & LUFFAU, G. (1974). Phosphorylcholine-bearing components in homogenates of nematodes. European Journal of Immunology 4, 637-639.
33. PFEFFER, S. R. & ROTHMAN, J. E. (1987). Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Annual Review of Biochemistry 56, 829-852.
34. STEPEK, G., AUCHIE, M., TATE, R., WATSON, K., RUSSELL, D. G., DEVANEY, E. & HARNETT, W. (2002). Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific. Parasitology 125, 155-164.
35. VANCE, D. E., TRIPP, E. M. & PADDON, H. B. (1980). Poliovirus increases phosphatidylcholine biosynthesis in HeLa cells by stimulation of the rate-limiting reaction catalyzed by CTP: phosphocholine cytidylyltransferase. Journal of Biological Chemistry 255, 1064-1069.
36. WALLER, P. J. (1997). Anthelmintic resistance. Veterinary Parasitology 72, 391-405.
37. WORLD HEALTH ORGANIZATION (1997). Prospects for the elimination of some TDR diseases. World Health Organization, Geneva.
38. WUHRER, M., RICKHOFF, S., DENNIS, R. D., LOCHNIT, G., SOBOSLAY, P. T., BAUMEISTER, S. & GEYER, R. (2000). Phosphocholine-containing zwitterionic glycosphingolipids of adult Onchocerca volvulus as highly conserved antigenic structures of parasitic nematodes. The Biochemical Journal 348, 417-423.