The serum fatty acids myristic acid and linoleic acid are better predictors of serum cholesterol concentrations when measured as molecular percentages rather than as absolute concentrations

American Journal of Clinical Nutrition

Volumn 91, Issue 2, 2010, Pages 398-405

  Bradbury, Kathryn E ^a   Murray Skeaff, C ^a   Green, Timothy J ^a   Gray, Andrew R ^a   Crowe, Francesca L ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; LINOLEIC ACID; MYRISTIC ACID; PHOSPHOLIPID;

ADOLESCENT; ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FAT INTAKE; FEMALE; HUMAN; MALE; PHOSPHOLIPID BLOOD LEVEL;

ADOLESCENT; ADULT; AGED; CHOLESTEROL; CROSS-SECTIONAL STUDIES; DIETARY FATS; HUMANS; LINEAR MODELS; LINOLEIC ACID; MIDDLE AGED; MYRISTIC ACID; NEW ZEALAND; YOUNG ADULT;

EID: 75649090807     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.3945/ajcn.2009.28159     Document Type: Article

References (26)

1. Hodson L, Skeaff CM, Fielding BA. Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake. Prog Lipid Res 2008;47:348-80.
2. Baylin A, Campos H. The use of fatty acid biomarkers to reflect dietary intake. Curr Opin Lipidol 2006;17:22-7.
3. Jenab M, Slimani N, Bictash M, Ferrari P, Bingham S. Biomarkers in nutritional epidemiology: applications, needs and new horizons. Hum Genet 2009;125:507-25.
4. Zock PL, Mensink RP, Harryvan J, de Vries JHM, Katan MB. Fatty acids in serum cholesteryl esters as quantitative biomarkers of dietary intake in humans. Am J Epidemiol 1997;145:1114-22.
5. Wolk A, Furuheim M, Vessby B. Fatty acid composition of adipose tissue and serum lipids are valid biological markers of dairy fat intake in men. J Nutr 2001;131:828-33.
6. Skeaff CM, Gowans S. Home use of margarine is an important determinant of plasma trans fatty acid status: a biomarker study. Br J Nutr 2006;96:377-83.
7. Biong AS, Berstad P, Pedersen J. Biomarkers for intake of dairy fat and dairy products. Eur J Lipid Sci Technol 2006;108:827-34.
8. Zock PL, de Vries JH, Katan MB. Impact of myristic acid versus palmitic acid on serum lipid and lipoprotein levels in healthy women and men. Arterioscler Thromb 1994;14:567-75.
9. Wilke M, French M, Goh Y, Ryan E, Jones P, Clandinin M. Synthesis of specific fatty acids contributes to VLDL-triacylglycerol composition in humans with and without type 2 diabetes. Diabetologia 2009;52:1628-37.
10. Chow C. Fatty acid composition of plasma phospholipids and risk of prostate cancer. Am J Clin Nutr 2009;89:1946.
11. Crowe F. Reply to CK Chow. Am J Clin Nutr 2009;89:1946-7.
12. Mensink RP, Zock PL, Kester AD, Katan MB. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr 2003;77:1146-55.
13. Clarke R, Frost C, Collins R, Appleby P, Peto R. Dietary lipids and blood cholesterol: quantitative meta-analysis of metabolic ward studies. BMJ 1997;314:112-7.
14. Kris-Etherton PM, Yu S. Individual fatty acid effects on plasma lipids and lipoproteins: human studies. Am J Clin Nutr 1997;65(5 suppl):1628S-44S.
15. Crowe FL, Skeaff CM, Green TJ, Gray AR. Serum fatty acids as biomarkers of fat intake predict serum cholesterol concentrations in a population-based survey of New Zealand adolescents and adults. Am J Clin Nutr 2006;83:887-94.
16. Parnell WR, Wilson NC, Russell DG. Methodology of the 1997 New Zealand National Nutrition Survey. N Z Med J 2001;114:123-6.
17. Quigley RJ, Watts C. Food comes first: methodologies for the National Nutrition Survey of New Zealand. Wellington, New Zealand: Ministry of Health, 1997.
18. Skeaff CM, Mann JI, McKenzie J, Wilson NC, Russell DG. Declining levels of total serum cholesterol in adult New Zealanders. N Z Med J 2001;114:131-4.
19. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959;37:911-7.
20. Howell WH, McNamara DJ, Tosca MA, Smith BT, Gaines JA. Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis. Am J Clin Nutr 1997;65:1747-64.
21. Schwertner HA, Mosser EL. Comparison of lipid fatty acids on a concentration basis vs weight percentage basis in patients with and without coronary artery disease or diabetes. Clin Chem 1993;39:659-63.
22. McPherson PAC, Young IS, McKibben B, McEneny J. High density lipoprotein subfractions: isolation, composition, and their duplicitous role in oxidation. J Lipid Res 2007;48:86-95.
23. Lewington S, Whitlock G, Clarke R, et al; Prospective Studies Collaboration. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55 000 vascular deaths. Lancet 2007;370:1829-39.
24. Hjartå ker A, Lund E, Bjerve KS. Serum phospholipid fatty acid composition and habitual intake of marine foods registered by a semi-quantitative food frequency questionnaire. Eur J Clin Nutr 1997;51:736-42.
25. Kuriki K, Nagaya T, Tokudome Y, et al. Plasma concentrations of (n-3) highly unsaturated fatty acids are good biomarkers of relative dietary fatty acid intakes: a cross-sectional study. J Nutr 2003;133:3643-50.
26. Thompson FE, Byers T. Dietary assessment resource manual. J Nutr 1994;124:2245S-317S.