Background light produces a recoverin-dependent modulation of activated-rhodopsin lifetime in mouse rods

Journal of Neuroscience

Volumn 30, Issue 4, 2010, Pages 1213-1220

  Chen, Ching Kang ^a   Woodruff, Michael L ^b   Chen, Frank S ^a   Chen, Desheng ^a   Fain, Gordon L ^b,c  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JULES STEIN EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOVERIN; RHODOPSIN; RHODOPSIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; ENZYME INHIBITION; LIGHT EXPOSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RETINA ROD;

ANIMALS; CALCIUM; CALCIUM SIGNALING; G-PROTEIN-COUPLED RECEPTOR KINASE 1; LIGHT; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PHOTIC STIMULATION; REACTION TIME; RECOVERIN; RETINAL ROD PHOTORECEPTOR CELLS; RHODOPSIN; TIME FACTORS; VISION, OCULAR;

EID: 75349111124     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4353-09.2010     Document Type: Article

References (28)

1. Ames JB, Levay K, Wingard JN, Lusin JD, Slepak VZ (2006) Structural basis for calcium-induced inhibition of rhodopsin kinase by recoverin. J Biol Chem 281:37237-37245.
2. Burns ME, Pugh EN Jr (2009) RGS9 concentration matters in rod phototransduction. Biophys J 97:1538-1547.
3. Chen C-K, Inglese J, Lefkowitz RJ, Hurley JB (1995) Ca(2+)-dependent interaction of recoverin with rhodopsin kinase. J Biol Chem 270:18060-18066.
4. Chen C-K, Burns ME, Spencer M, Niemi GA, Chen J, Hurley JB, Baylor DA, Simon MI (1999) Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. Proc Natl Acad Sci U S A 96:3718-3722.
5. Chen J, Makino CL, Peachey NS, Baylor DA, Simon MI (1995) Mechanisms of rhodopsin inactivation in vivo as revealed by a COOH-terminal truncation mutant. Science 267:374-377.
6. Dizhoor AM, Woodruff ML, Olshevskaya EV, Cilluffo MC, Cornwall MC, Sieving PA, Fain GL (2008) Night blindness and the mechanism of constitutive signaling of mutant G90D rhodopsin. J Neurosci 28:11662-11672.
7. Erickson MA, Lagnado L, Zozulya S, Neubert TA, Stryer L, Baylor DA (1998) The effect of recombinant recoverin on the photoresponse of truncated rod photoreceptors. Proc Natl Acad Sci U S A 95:6474-6479.
8. Fain GL (2003) Sensory transduction. Sunderland, MA: Sinauer.
9. Fain GL, Matthews HR, Cornwall MC, Koutalos Y (2001) Adaptation in vertebrate photoreceptors. Physiol Rev 81:117-151.
10. Gray-Keller MP, Polans AS, Palczewski K, Detwiler PB (1993) The effect of recoverin-like calcium-binding proteins on the photoresponse of retinal rods. Neuron 10:523-531.
11. Higgins MK, Oprian DD, Schertler GF (2006) Recoverin binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase, inhibiting rhodopsin phosphorylation without affecting catalytic activity of the kinase. J Biol Chem 281:19426-19432.
12. Kawamura S (1993) Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin. Nature 362:855-857.
13. Klenchin VA, Calvert PD, Bownds MD (1995) Inhibition of rhodopsin kinase by recoverin. Further evidence for a negative feedback system in phototransduction. J Biol Chem 270:16147-16152.
14. Krispel CM, Chen D, Melling N, Chen YJ, Martemyanov KA, Quillinan N, Arshavsky VY, Wensel TG, Chen C-K, Burns ME (2006) RGS expression rate-limits recovery of rod photoresponses. Neuron 51:409-416.
15. Leskov IB, Klenchin VA, Handy JW, Whitlock GG, Govardovskii VI, Bownds MD, Lamb TD, Pugh EN Jr, Arshavsky VY (2000) The gain of rod phototransduction: reconciliation of biochemical and electrophysiological measurements. Neuron 27:525-537.
16. Makino CL, Dodd RL, Chen J, Burns ME, Roca A, Simon MI, Baylor DA (2004) Recoverin regulates light-dependent phosphodiesterase activity in retinal rods. J Gen Physiol 123:729-741.
17. 2+ concentration during the bright flash response. J Gen Physiol 109:141-146.
18. 2+ early in phototransduction by 9-demethylretinal. J Gen Physiol 118:377-390.
19. Mendez A, Burns ME, Roca A, Lem J, Wu LW, Simon MI, Baylor DA, Chen J (2000) Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron 28:153-164.
20. Mendez A, Burns ME, Sokal I, Dizhoor AM, Baehr W, Palczewski K, Baylor DA, Chen J (2001) Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors. Proc Natl Acad Sci U S A 98:9948-9953.
21. Otto-Bruc AE, Fariss RN, Van Hooser JP, Palczewski K (1998) Phosphorylation of photolyzed rhodopsin is calcium-insensitive in retina permeabilized by alpha-toxin. Proc Natl Acad Sci U S A 95:15014-15019.
22. Palczewski K, Ohguro H, Premont RT, Inglese J (1995) Rhodopsin kinase autophosphorylation. Characterization of site-specific mutations. J Biol Chem 270:15294-15298.
23. Pugh EN Jr, Nikonov S, Lamb TD (1999) Molecular mechanisms of vertebrate photoreceptor light adaptation. Curr Opin Neurobiol 9:410-418.
24. Sampath AP, Strissel KJ, Elias R, Arshavsky VY, McGinnis JF, Chen J, Kawamura S, Rieke F, Hurley JB (2005) Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina. Neuron 46:413-420.
25. Strissel KJ, Lishko PV, Trieu LH, Kennedy MJ, Hurley JB, Arshavsky VY (2005) Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors. J Biol Chem 280:29250-29255.
26. Tsang SH, Woodruff ML, Chen C-K, Yamashita CY, Cilluffo MC, Rao AL, Farber DB, Fain GL (2006) GAP-independent termination of photoreceptor light response by excess γ subunit of the cGMP-phosphodiesterase. J Neurosci 26:4472-4480.
27. Woodruff ML, Sampath AP, Matthews HR, Krasnoperova NV, Lem J, Fain GL (2002) Measurement of cytoplasmic calcium concentration in the rods of wild-type and transducin knock-out mice. J Physiol 542:843-854.
28. Woodruff ML, Janisch KM, Peshenko IV, Dizhoor AM, Tsang SH, Fain GL (2008) Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors. J Neurosci 28:2064-2074.