Actions of Ca2+ on an early stage in phototransduction revealed by the dynamic fall in Ca2+ concentration during the bright flash response

Journal of General Physiology

Volumn 109, Issue 2, 1997, Pages 141-146

  Matthews, H R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

calcium; light adaptation; photoreceptor; retinal rod; rhodopsin

Indexed keywords

CALCIUM ION; RHODOPSIN; CALCIUM; CARRIER PROTEIN; POTASSIUM DEPENDENT SODIUM CALCIUM EXCHANGER; POTASSIUM-DEPENDENT SODIUM-CALCIUM EXCHANGER; SODIUM; SODIUM CALCIUM EXCHANGE PROTEIN;

AMBYSTOMA; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; LIGHT ADAPTATION; NONHUMAN; PHOTOSTIMULATION; PHOTOTRANSDUCTION; RETINA ROD; RETINA ROD OUTER SEGMENT; ANIMAL; IN VITRO STUDY; METABOLISM; PHOTORECEPTOR; PHYSIOLOGY;

AMBYSTOMA; ANIMALS; CALCIUM; CARRIER PROTEINS; PHOTIC STIMULATION; PHOTORECEPTORS; PHOTOTRANSDUCTION; ROD OUTER SEGMENTS; RODS (RETINA); SODIUM; SODIUM-CALCIUM EXCHANGER;

EID: 0030614678     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.109.2.141     Document Type: Article

References (32)

1. Cervetto, L., L. Lagnado, R.J. Perry, D.W. Robinson, and P.A. McNaughton. 1989. Extrusion of calcium from rod outer segments is driven by both sodium and potassium gradients. Nature (Lond.). 337:740-743.
2. 2+-dependent interaction of recoverin with rhodopsin kinase. J. Biol. Chem. 270:18060-18066.
3. Cobbs, W.H., and E.N. Pugh. 1987. Kinetics and components of the flash photocurrent of isolated retinal rods of the larval salamander, Ambystoma tigrinum. J. Physiol. (Lond.). 394:529-572.
4. Fain, G.L., T.D. Lamb, H.R. Matthews, and R.L.W. Murphy. 1989. Cytoplasmic calcium concentration as the messenger for light adaptation in salamander rods. J. Physiol. (Lond.). 416:215-243.
5. Gray-Keller, M.P., and P.B. Detwiler. 1994. The calcium feedback signal in the phototransduction cascade of vertebrate rods. Neuron. 13:849-861.
6. Hodgkin, A.L., P.A. McNaughton, and B.J. Nunn. 1985. The ionic selectivity and calcium dependence of the light-sensitive pathway in toad rods. J. Physiol. (Lond.). 358:447-468.
7. Hodgkin, A.L., P.A. McNaughton, and B.J. Nunn. 1987. Measurement of sodium-calcium exchange in salamander rods. J. Physiol. (Lond.). 391:347-370.
8. Hsu, Y.-T., and R.S. Molday. 1993. Modulation of the cGMP-gated channel of rod photoreceptor cells by calmodulin. Nature (Lond.). 361:76-79.
9. Jones, G.J. 1995. Light adaptation and the rising phase of the flash photocurrent in rent of salamander retinal rods. J. Physiol. (Lond.). 487: 441-451.
10. Kawamura, S. 1993. Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin. Nature (Lond.). 362:855-857.
11. Kawamura, S., and M. Murakami. 1991. Calcium-dependent regulation of cyclic GMP phosphodiesterase by a protein from frog retinal rods. Nature (Lond.). 349:420-423.
12. Koch, K.-W., and L. Stryer. 1988. Highly cooperative feedback control of retinal rod guanylate cyclase by calcium ions. Nature (Lond.). 334:64-66.
13. Koutalos, Y., K. Nakatani, T. Tamura, and K.-W. Yau. 1995a. Characterization of guanylate cyclase activity in single retinal rod outer segments. J. Gen. Physiol. 106:863-890.
14. Koutalos, Y., K. Nakatani, and K.-W. Yau. 1995b. The cGMP-phosphodiesterase and its contribution to sensitivity regulation in retinal rods. J. Gen. Physiol. 106:891-921.
15. Lagnado, L., and D.A. Baylor. 1994. Calcium controls light-triggered formation of catalytically active rhodopsin. Nature (Lond.). 367:273-277.
16. Lolley, R.N., and E. Racz. 1982. Calcium modulation of cyclic GMP synthesis in rat visual cells. Vision Res. 22:1481-1486.
17. i. J. Gen. Physiol. 107:19-34.
18. Matthews, H.R. 1994. A piezo translator for effecting fast solution changes on isolated cells. J. Physiol. (Lond.). 480:3-4P. (Abstr.).
19. Matthews, H.R. 1995. Effects of lowered cytoplasmic calcium concentration and light on the responses of salamander rod photoreceptors. J. Physiol. (Lond.). 484:267-286.
20. 2+ in the adaptation of responses to saturating flashes in salamander rods. J. Physiol. (Lond.). 490:1-15.
21. Matthews, H.R., R.L.W. Murphy, G.L. Fain, and T.D. Lamb. 1988. Photoreceptor light adaptation is mediated by cytoplasmic calcium concentration. Nature (Lond.). 334:67-69.
22. McCarthy, S.T., J.P. Younger, and W.G. Owen. 1994. Free calcium concentrations in bullfrog rods determined in the presence of multiple forms of fura-2. Biophys. J. 67:2076-2089.
23. McNaughton, P.A., L. Cervetto, and B.J. Nunn. 1986. Measurement of the intracellular free calcium concentration in salamander rods. Nature (Lond.). 322:261-263.
24. Murnick, J.G., and T.D. Lamb. 1996. Kinetics of desensitization induced by saturating flashes in toad and salamander rods. J. Physiol. (Lond.). 495:1-14.
25. 2+ modulation of the cGMP-gated channel of bullfrog retinal rod photoreceptors. J. Physiol. (Lond.). 484:69-76.
26. Nakatani, K., and K.-W. Yau. 1988. Calcium and light adaptation in retinal rods and cones. Nature (Lond.). 334:69-71.
27. Pepperberg, D.R., M.C. Cornwall, M. Kahlert, K.P. Hoffmann, J. Jin, G.J. Jones, and H. Ripps. 1992. Light-dependent delay in the falling phase of the retinal rod photoresponse. Vis. Neurosci. 8:9-18.
28. Pepperberg, D.R., J. Jin, and G.J. Jones. 1994. Modulation of transduction gain in light adaptation of retinal rods. Vis. Neurosci. 11: 53-62.
29. Ratto, G.M., R. Payne, W.G. Owen, and R.Y. Tsien. 1987. The concentration of cytosolic free calcium in vertebrate rod outer segments measured with fura-2. J. Neurosci. 8:3240-3246.
30. Yau, K.-W., and K. Nakatani. 1984a. Cation selectivity of light-sensitive conductance in retinal rods. Nature (Lond.). 309:352-354.
31. Yau, K.-W., and K. Nakatani. 1984b. Electrogenic Na-Ca exchange in retinal rod outer segment. Nature (Lond.). 311:661-663.
32. Yau, K.-W., and K. Nakatani. 1985. Light-induced reduction of cytoplasmic free calcium in retinal rod outer segment. Nature (Lond.). 313:579-582.