Prolongation of actions of Ca2+ early in phototransduction by 9-demethylretinal

Journal of General Physiology

Volumn 118, Issue 4, 2001, Pages 377-390

  Matthews, Hugh R ^a,d   Cornwall, M C ^b   Crouch, R K ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d PHYSIOLOGICAL LABORATORY   (United Kingdom)

Author keywords

Adaptation; Calcium; Photoreceptor; Retinal rod; Rhodopsin

Indexed keywords

11 CIS RETINAL; 9 NORRETINAL; CALCIUM ION; PIGMENT; RETINAL; RHODOPSIN; RINGER LACTATE SOLUTION; UNCLASSIFIED DRUG; 9 DEMETHYLRETINAL; 9-DEMETHYLRETINAL; CALCIUM; DRUG DERIVATIVE;

ADAPTATION; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CHROMATOPHORE; CONTROLLED STUDY; MATHEMATICAL ANALYSIS; NONHUMAN; PHOSPHORYLATION; PHOTORECEPTOR; PHOTOTRANSDUCTION; RETINA ROD; SALAMANDER; AMBYSTOMA; ANIMAL; DRUG EFFECT; LIGHT; PHYSIOLOGY; TIME;

ADAPTATION, PHYSIOLOGICAL; AMBYSTOMA; ANIMALS; CALCIUM; LIGHT; PHOTORECEPTORS, VERTEBRATE; PHOTOTRANSDUCTION; RETINALDEHYDE; RODS (RETINA); TIME FACTORS;

EID: 0034740555     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.118.4.377     Document Type: Article

References (62)

1. Onset of feedback reactions underlying vertebrate rod photoreceptor light adaptation
2. Extrusion of calcium from rod outer segments is driven by both sodium and potassium gradients
3. 2+-dependent interaction of recoverin with rhodopsin kinase
4. Mechanisms of rhodopsin inactivation in vivo as revealed by a COOH-terminal truncation mutant
5. Factors affecting the regeneration of rhodopsin in the isolated amphibian retina
6. Electrophysiological methods for measurement of activation of phototransduction by bleached visual pigment in salamander photoreceptors
7. Relief of opsin desensitization and prolonged excitation of rod photoreceptors by 9-desmethylretinal
8. Evidence for the prolonged photoactivated lifetime of an analog visual pigment containing 11-cis 9-desmethylretinal
9. Photosensitivity
10. The effect of recombinant recoverin on the photoresponse of truncated rod photoreceptors
11. Cytoplasmic calcium concentration as the messenger for light adaptation in salamander rods
12. Adaptation in vertebrate photoreceptors
13. The calcium feedback signal in the phototransduction cascade of vertebrate rods
14. Role of the C9 methyl group in rhodopsin activation: Characterization of mutant opsins with the artificial chromophore 11-cis-9-demethylretinal
15. Absorption spectra and linear dichroism of some amphibian photoreceptors
16. The ionic selectivity and calcium dependence of the light-sensitive pathway in toad rods
17. Measurement of sodium-calcium exchange in salamander rods
18. 2+ and recoverin on rod photoreceptor function in intact retinas
19. Light adaptation and the rising phase of the flash photocurrent of salamander retinal rods
20. Visual pigment bleaching in isolated salamander retinal cones. Microspectrophotometry and light adaptation
21. Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin
22. Calcium-dependent regulation of cyclic GMP phosphodiesterase by a protein from frog retinal rods
23. Inhibition of rhodopsin kinase by recoverin. Further evidence for a negative feedback system in phototransduction
24. Light-regulated binding of rhodopsin kinase and other proteins to cattle photoreceptor membranes
25. Calcium controls light-triggered formation of catalytically active rhodopsin
26. Photoreceptor spectral sensitivities - Common shape in the long-wavelength region
27. i
28. Effects of lowered cytoplasmic calcium concentration and light on the responses of salamander rod photoreceptors
29. 2+ in the adaptation of responses to saturating flashes in salamander rods
30. 2+ during the bright flash response
31. 2+ concentration in the salamander rod outer segment
32. 2+ early in phototransduction are prolonged by 9-desmethylrhodopsin
33. 2+ early in phototransduction by 9-desmethylretinal
34. Photoreceptor light adaptation is mediated by cytoplasmic calcium concentration
35. Free calcium concentrations in bullfrog rods determined in the presence of multiple forms of fura-2
36. Measurement of the intracellular free calcium concentration in salamander rods
37. Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites
38. Signaling states of rhodopsin. Retinal provides a scaffold for activating proton transfer switches
39. Reduced light-dependent phosphorylation of an analog visual pigment containing 9-demethylretinal as its chromophore
40. Kinetics of desensitization induced by saturating flashes in toad and salamander rods
41. Calcium and light adaptation in retinal rods and cones
42. Kinetics of recovery of the dark-adapted salamander rod photoresponse
43. The role of steady phosphodiesterase activity in the kinetics and sensitivity of the light-adapted salamander rod photoresponse
44. Phosphorylation of photolyzed rhodopsin is calcium-insensitive in retina permeabilized by alpha-toxin
45. Rod outer segment retinol dehydrogenase: Substrate-specificity and role in phototransduction
46. Light-dependent delay in the falling phase of the retinal rod photoresponse
47. Modulation of transduction gain in light adaptation of retinal rods
48. Molecular mechanisms of vertebrate photoreceptor light adaptation
49. The concentration of cytosolic free calcium in vertebrate rod outer segments measured with fura-2
50. G-protein deactivation is rate-limiting for shut-off of the hototransduction cascade
51. 2+ in salamander rods
52. 2+ concentration in salamander cone photoreceptors
53. Molecular mechanism of S-modulin action: Binding target and effect of ATP
54. A splice variant of arrestin: Molecular-cloning and localization in bovine retina
55. The molecular origin of the inhibition of transducin activation in rhodopsin lacking the 9-methyl group of the retinal chromophore: A UV-Vis and FTIR spectroscopic study
56. Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments
57. Prolonged photoresponses in transgenic mouse rods lacking arrestin
58. Effect of ions on the light-sensitive current in retinal rods
59. Cation selectivity of light-sensitive conductance in retinal rods
60. Electrogenic Na-Ca exchange in retinal rod outer segment
61. Light-induced reduction of cytoplasmic free calcium in retinal rod outer segment
62. Light-dependent control of calcium in intact rods of the bullfrog Rana catesbeiana