-
2
-
-
0036164731
-
Genetic linkage and association studies of type 1 diabetes: challenges and rewards
-
Field L.L., Genetic linkage and association studies of type 1 diabetes: challenges and rewards. Diabetologia 2002; 45: 21-35
-
(2002)
Diabetologia
, vol.45
, pp. 21-35
-
-
Field, L.L.1
-
3
-
-
0027200763
-
Susceptibility to insulin dependent diabetes mellitus maps to a 4
-
Lucassen A.M, Julier C, Beressi JP, Boitard C, Froguel P, Lathrop M, Bell JI. Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associatedVNTR. Nat Genet 1993; 4: 305-10
-
(1993)
1 kb segment of DNA spanning the insulin gene and associatedVNTR. Nat Genet
, vol.4
, pp. 305-310
-
-
Lucassen, A.M.1
Julier, C.2
Beressi, J.P.3
Boitard, C.4
Froguel, P.5
Lathrop, M.6
Bell, J.I.7
-
4
-
-
0029953858
-
CTLA4 ligation blocks CD28-dependent T cell activation
-
Walunas TL, Bakker CY, Bluestone JA. CTLA4 ligation blocks CD28-dependent T cell activation. J Exp Med 1996; 183: 2541-50
-
(1996)
J Exp Med
, vol.183
, pp. 2541-2550
-
-
Walunas, T.L.1
Bakker, C.Y.2
Bluestone, J.A.3
-
5
-
-
0030762536
-
Regulation of T and B cell responses by modulating interactions between CD28/CTLA4 and their ligands, CD80 and CD86
-
Lane P. Regulation of T and B cell responses by modulating interactions between CD28/CTLA4 and their ligands, CD80 and CD86. Ann NY Acad Sci 1997; 815: 392-400
-
(1997)
Ann NY Acad Sci
, vol.815
, pp. 392-400
-
-
Lane, P.1
-
6
-
-
0031434409
-
CTLA4 gene polymorphism confers genetic susceptibility to Graves' disease in Japanese
-
Yanagawa T, Taniyama M, Enomoto S, Gomi K, Maruyama H, Ban Y, Saruta T. CTLA4 gene polymorphism confers genetic susceptibility to Graves' disease in Japanese. Thyroid 1997; 7: 843-6
-
(1997)
Thyroid
, vol.7
, pp. 843-846
-
-
Yanagawa, T.1
Taniyama, M.2
Enomoto, S.3
Gomi, K.4
Maruyama, H.5
Ban, Y.6
Saruta, T.7
-
7
-
-
0031014716
-
CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and type 1 diabetes mellitus
-
Donner H, Rau H, Walfish PG, Braun J, Siegmund T, Finke R, HerwigJ, Usadel KH, Badenhoop K. CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and type 1 diabetes mellitus. J Clin Endocrinol Metab 1997; 82: 143-6
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 143-146
-
-
Donner, H.1
Rau, H.2
Walfish, P.G.3
Braun, J.4
Siegmund, T.5
Finke, R.6
Herwig, J.7
Usadel, K.H.8
Badenhoop, K.9
-
8
-
-
0033065858
-
CTLA4 polymorphism in Spanish patients with rheumatoid arthritis
-
Gonzales-Escribano MF, Rodriguez R, Valenzuela A, Garcia A, Garcia-Lozano JR, Nunez-Roldan A. CTLA4 polymorphism in Spanish patients with rheumatoid arthritis. Tissue Antigens 1999; 53: 296-300
-
(1999)
Tissue Antigens
, vol.53
, pp. 296-300
-
-
Gonzales-Escribano, M.F.1
Rodriguez, R.2
Valenzuela, A.3
Garcia, A.4
Garcia-Lozano, J.R.5
Nunez-Roldan, A.6
-
9
-
-
8944259914
-
The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes
-
Nistico L, Buzzetti R, Pritchard LE, Van der Auwera B, Giovannini C, Bosi E, Larrad MT, Rios MS, Chow CC, Cockram CS, Jacobs K, Mijovic C, Bain SC, Barnett AH, Vandewalle CL, Schuit F, Gorus FK, Tosi R, Pozzilli P, Todd JA. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum Mol Genet 1996; 5: 1075-80
-
(1996)
Belgian Diabetes Registry. Hum Mol Genet
, vol.5
, pp. 1075-1080
-
-
Nistico, L.1
Buzzetti, R.2
Pritchard, L.E.3
Van der Auwera, B.4
Giovannini, C.5
Bosi, E.6
Larrad, M.T.7
Rios, M.S.8
Chow, C.C.9
Cockram, C.S.10
Jacobs, K.11
Mijovic, C.12
Bain, S.C.13
Barnett, A.H.14
Vandewalle, C.L.15
Schuit, F.16
Gorus, F.K.17
Tosi, R.18
Pozzilli, P.19
Todd, J.A.20
more..
-
10
-
-
8544274482
-
Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups
-
Marron MP, Raffel LJ, Garchon HJ, Jacob CO, Serrano-Rios M, Martinez Larrad MT, Teng WP, Park Y, Zhang ZX, Goldstein DR, Tao YW, Beaurain G, Bach JF, Huang HS, Luo DF, Zeidler A, Rotter JI, Yang MC, Modilevsky T, Maclaren NK, She JX. Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups. Hum Mol Genet 1997; 6: 1275-82
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1275-1282
-
-
Marron, M.P.1
Raffel, L.J.2
Garchon, H.J.3
Jacob, C.O.4
Serrano-Rios, M.5
Martinez Larrad, M.T.6
Teng, W.P.7
Park, Y.8
Zhang, Z.X.9
Goldstein, D.R.10
Tao, Y.W.11
Beaurain, G.12
Bach, J.F.13
Huang, H.S.14
Luo, D.F.15
Zeidler, A.16
Rotter, J.I.17
Yang, M.C.18
Modilevsky, T.19
Maclaren, N.K.20
She, J.X.21
more..
-
11
-
-
0033963054
-
Association of CTLA4 gene A-G polymorphism with type 1 diabetes in Chinese children
-
Lee YJ, Huang FY, Lo FS, Wang WC, Hsu CH, Kao HA, Yang TY, Chang JG. Association of CTLA4 gene A-G polymorphism with type 1 diabetes in Chinese children. Clin Endocrinol (Oxf) 2000; 52: 153-7
-
(2000)
Clin Endocrinol (Oxf)
, vol.52
, pp. 153-157
-
-
Lee, Y.J.1
Huang, F.Y.2
Lo, F.S.3
Wang, W.C.4
Hsu, C.H.5
Kao, H.A.6
Yang, T.Y.7
Chang, J.G.8
-
12
-
-
0033045012
-
Lack of association between CTLA-4 gene polymorphism and IDDM in Japanese subjects
-
Yanagawa T, Maruyama T, Gomi K, Taniyama M, Kasuga A, Ozawa Y, Terauchi M, Hirose H, Maruyama H, Saruta T. Lack of association between CTLA-4 gene polymorphism and IDDM in Japanese subjects. Autoimmunity 1999; 29: 53-6
-
(1999)
Autoimmunity
, vol.29
, pp. 53-56
-
-
Yanagawa, T.1
Maruyama, T.2
Gomi, K.3
Taniyama, M.4
Kasuga, A.5
Ozawa, Y.6
Terauchi, M.7
Hirose, H.8
Maruyama, H.9
Saruta, T.10
-
13
-
-
0030952822
-
Analysis of candidate genes for susceptibility to type 1 diabetes: a case-control and family-association study of genes on chromosome 2q31-35
-
Owerbach D, Naya FJ, Tsai MJ, Allander SV, Powell DR, Gabbay KH. Analysis of candidate genes for susceptibility to type 1 diabetes: a case-control and family-association study of genes on chromosome 2q31-35. Diabetes 1997; 46: 1069-74
-
(1997)
Diabetes
, vol.46
, pp. 1069-1074
-
-
Owerbach, D.1
Naya, F.J.2
Tsai, M.J.3
Allander, S.V.4
Powell, D.R.5
Gabbay, K.H.6
-
14
-
-
0032877747
-
Genetic susceptibility to type 1 diabetes: clinical and molecular heterogeneity of IDDM1 and IDDM12 in a German population
-
Badenhoop K, Donner H, Pani M, Rau H, Siegmund T, Braun J. Genetic susceptibility to type 1 diabetes: clinical and molecular heterogeneity of IDDM1 and IDDM12 in a German population. Exp Clin Endocrinol Diabetes 1999; 107 (Suppl 3): S89-92
-
(1999)
Exp Clin Endocrinol Diabetes
, vol.107
, Issue.SUPPL. 3
-
-
Badenhoop, K.1
Donner, H.2
Pani, M.3
Rau, H.4
Siegmund, T.5
Braun, J.6
-
15
-
-
0028107348
-
Discrimination of human HLA-DRB1 alleles by PCRSSCP (single-strand conformation polymorphism) method
-
Bannai M, Tokunaga K, Lin L, Kuwata S, Mazda T, Amaki I, Fujisawa K, Juji T. Discrimination of human HLA-DRB1 alleles by PCRSSCP (single-strand conformation polymorphism) method. Eur J Immunogenet 1994; 21: 1-9
-
(1994)
Eur J Immunogenet
, vol.21
, pp. 1-9
-
-
Bannai, M.1
Tokunaga, K.2
Lin, L.3
Kuwata, S.4
Mazda, T.5
Amaki, I.6
Fujisawa, K.7
Juji, T.8
-
16
-
-
0344979757
-
High resolution HLA-DQB1 typing by combination of PCR-RFLP and PCR-SSCP
-
Park MH, Whang DH, Kang SJ. High resolution HLA-DQB1 typing by combination of PCR-RFLP and PCR-SSCP. Hum Immunol 1999; 60: 901-7
-
(1999)
Hum Immunol
, vol.60
, pp. 901-907
-
-
Park, M.H.1
Whang, D.H.2
Kang, S.J.3
-
17
-
-
7044250867
-
Analysis of children with type 1 diabetes in Korea: high prevalence of specific antiislet autoantibodies, immunogenetic similarities to Western populations with unique haplotypes, and lack of discrimination by aspartic acid at position 57 of DQB
-
Yu J, Shin CH, Yang SW, Park MH, Eisenbarth GS. Analysis of children with type 1 diabetes in Korea: high prevalence of specific antiislet autoantibodies, immunogenetic similarities to Western populations with unique haplotypes, and lack of discrimination by aspartic acid at position 57 of DQB. Clin Immunol 2004; 113: 318-25
-
(2004)
Clin Immunol
, vol.113
, pp. 318-325
-
-
Yu, J.1
Shin, C.H.2
Yang, S.W.3
Park, M.H.4
Eisenbarth, G.S.5
-
18
-
-
0030598879
-
An Mse I RFLP in the human CTLA4 promoter
-
Deichmann K, Heinzmann A, Bruggenolte E, Forster J, Kuehr J. An Mse I RFLP in the human CTLA4 promoter. Biochem Biophys Res Commun 1996; 225: 817-8
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 817-818
-
-
Deichmann, K.1
Heinzmann, A.2
Bruggenolte, E.3
Forster, J.4
Kuehr, J.5
-
19
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994; 1: 405-13
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
Thompson, C.B.7
Bluestone, J.A.8
-
20
-
-
0010690218
-
Polymorphism in the promoter and exon 1 of the cytotoxic T lymphocyte antigen-4 gene associated with autoimmune thyroid disease in Koreans
-
Park YJ, Chung HK, Park DJ, Kim WB, Kim SW, Koh JJ, Cho BY. Polymorphism in the promoter and exon 1 of the cytotoxic T lymphocyte antigen-4 gene associated with autoimmune thyroid disease in Koreans. Thyroid 2000; 10: 453-9
-
(2000)
Thyroid
, vol.10
, pp. 453-459
-
-
Park, Y.J.1
Chung, H.K.2
Park, D.J.3
Kim, W.B.4
Kim, S.W.5
Koh, J.J.6
Cho, B.Y.7
-
21
-
-
0041989837
-
Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children
-
Mochizuki M, Amemiya S, Kobayashi K, Kobayashi K, Shimura Y, Ishihara T, Nakagomi Y, Onigata K, Tamai S, Kasuga A, Nanazawa S. Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children. Diabetes Care 2003; 26: 843-7
-
(2003)
Diabetes Care
, vol.26
, pp. 843-847
-
-
Mochizuki, M.1
Amemiya, S.2
Kobayashi, K.3
Kobayashi, K.4
Shimura, Y.5
Ishihara, T.6
Nakagomi, Y.7
Onigata, K.8
Tamai, S.9
Kasuga, A.10
Nanazawa, S.11
-
22
-
-
0032737598
-
CTLA4 gene polymorphism correlates with the mode of onset and presence of ICA512 Ab in Japanese type 1 diabetes
-
Abe T, Takino H, Yamasaki H, Ozaki M, Sera Y, Kondo H, Sakamaki H, Kawasaki E, Awata T, Yamaguchi Y, Eguchi K. CTLA4 gene polymorphism correlates with the mode of onset and presence of ICA512 Ab in Japanese type 1 diabetes. Diabetes Res Clin Pract 1999; 46: 169-75
-
(1999)
Diabetes Res Clin Pract
, vol.46
, pp. 169-175
-
-
Abe, T.1
Takino, H.2
Yamasaki, H.3
Ozaki, M.4
Sera, Y.5
Kondo, H.6
Sakamaki, H.7
Kawasaki, E.8
Awata, T.9
Yamaguchi, Y.10
Eguchi, K.11
-
23
-
-
0031721837
-
No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies
-
Heward JM, Allahabadia A, Carr-Smith J, Daykin J, Cockram CS, Gordon C, Barnett AH, Franklyn JA, Gough SC. No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies. Clin Endocrinol (Oxf) 1998; 49: 331-4
-
(1998)
Clin Endocrinol (Oxf)
, vol.49
, pp. 331-334
-
-
Heward, J.M.1
Allahabadia, A.2
Carr-Smith, J.3
Daykin, J.4
Cockram, C.S.5
Gordon, C.6
Barnett, A.H.7
Franklyn, J.A.8
Gough, S.C.9
-
24
-
-
23644443079
-
Association of non-HLA genes with type 1 diabetes autoimmunity
-
Steck AK, Bugawan TL, Valdes AM, Emery LM, Blair A, Norris JM, Redondo MJ, Babu SR, Erlich HA, Eisenbarth GS, Rewers MJ. Association of non-HLA genes with type 1 diabetes autoimmunity. Diabetes 2005; 54: 2482-6
-
(2005)
Diabetes
, vol.54
, pp. 2482-2486
-
-
Steck, A.K.1
Bugawan, T.L.2
Valdes, A.M.3
Emery, L.M.4
Blair, A.5
Norris, J.M.6
Redondo, M.J.7
Babu, S.R.8
Erlich, H.A.9
Eisenbarth, G.S.10
Rewers, M.J.11
-
25
-
-
0035346140
-
CTLA-4 gene expression is influcenced by promoter and exon 1 polymorphisms
-
Ligers A, Teleshova N, Masterman T, Huang WX, Hillert J. CTLA-4 gene expression is influcenced by promoter and exon 1 polymorphisms. Genes Immun 2001; 2: 145-52
-
(2001)
Genes Immun
, vol.2
, pp. 145-152
-
-
Ligers, A.1
Teleshova, N.2
Masterman, T.3
Huang, W.X.4
Hillert, J.5
-
26
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda H, Howson JM, Esposito L, Heward J, Snook H, Chamberlain G, Rainbow DB, Hunter KM, Smith AN, Di Genova G, Herr MH, Dahlman I, Payne F, Smyth D, Lowe C, Twells RC, Howlett S, Healy B, Nutland S, Rance HE, Everett V, Smink LJ, Lam AC, Cordell HJ, Walker NM, Bordin C, Hulme J, Motzo C, Cucca F, Hess JF, Metzker ML, Rogers J, Gregory S, Allahabadia A, Nithiyananthan R, Tuomilehto-Wolf E, Tuomilehto J, Bingley P, Gillespie KM, Undlien DE, Ronningen KS, Guja C, Ionescu-Tirgoviste C, Savage DA, Maxwell AP, Carson DJ, Patterson CC, Franklyn JA, Clayton DG, Peterson LB, Wicker LS, Todd JA, Gough SC. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003; 423: 506-11
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
Heward, J.4
Snook, H.5
Chamberlain, G.6
Rainbow, D.B.7
Hunter, K.M.8
Smith, A.N.9
Di Genova, G.10
Herr, M.H.11
Dahlman, I.12
Payne, F.13
Smyth, D.14
Lowe, C.15
Twells, R.C.16
Howlett, S.17
Healy, B.18
Nutland, S.19
Rance, H.E.20
Everett, V.21
Smink, L.J.22
Lam, A.C.23
Cordell, H.J.24
Walker, N.M.25
Bordin, C.26
Hulme, J.27
Motzo, C.28
Cucca, F.29
Hess, J.F.30
Metzker, M.L.31
Rogers, J.32
Gregory, S.33
Allahabadia, A.34
Nithiyananthan, R.35
Tuomilehto-Wolf, E.36
Tuomilehto, J.37
Bingley, P.38
Gillespie, K.M.39
Undlien, D.E.40
Ronningen, K.S.41
Guja, C.42
Ionescu-Tirgoviste, C.43
Savage, D.A.44
Maxwell, A.P.45
Carson, D.J.46
Patterson, C.C.47
Franklyn, J.A.48
Clayton, D.G.49
Peterson, L.B.50
Wicker, L.S.51
Todd, J.A.52
Gough, S.C.53
more..
-
27
-
-
0034797762
-
CTLA4 gene polymorphism contributes to the mode of onset of diabetes with antiglutamic acid decarboxylase antibody in Japanese patients: genetic analysis of diabetic patients with antiglutamic acid decarboxylase antibody
-
Abe T, Yamaguchi Y, Takino H, Fujita N, Yamaguchi-Degawa M, Ozaki M, Yamakawa K, Sera Y, Sakamachi H, Eguchi K. CTLA4 gene polymorphism contributes to the mode of onset of diabetes with antiglutamic acid decarboxylase antibody in Japanese patients: genetic analysis of diabetic patients with antiglutamic acid decarboxylase antibody. Diabet Med 2001; 18: 726-31
-
(2001)
Diabet Med
, vol.18
, pp. 726-731
-
-
Abe, T.1
Yamaguchi, Y.2
Takino, H.3
Fujita, N.4
Yamaguchi-Degawa, M.5
Ozaki, M.6
Yamakawa, K.7
Sera, Y.8
Sakamachi, H.9
Eguchi, K.10
-
28
-
-
0033911987
-
Association of CTLA-4 gene A/G polymorphism in Japanese type 1 diabetic patients with younger age of onsetand autoimmune thyroid disease
-
Takara M, Komiya I, Kinjo Y, Tomoyose T, Yamashiro S, Akamine H, Masuda M, Takasu N. Association of CTLA-4 gene A/G polymorphism in Japanese type 1 diabetic patients with younger age of onsetand autoimmune thyroid disease. Diabetes Care 2000; 23: 975-8
-
(2000)
Diabetes Care
, vol.23
, pp. 975-978
-
-
Takara, M.1
Komiya, I.2
Kinjo, Y.3
Tomoyose, T.4
Yamashiro, S.5
Akamine, H.6
Masuda, M.7
Takasu, N.8
-
29
-
-
0031985460
-
No major role for the CTLA-4 gene in the association of autoimmune thyroid disease with IDDM
-
Djilali-Saiah I, Larger E, Harfouch-Hammoud E, Timsit J, Clerc J, Bertin E, Assan R, Boitard C, Bach JF, Caillat-Zucman S. No major role for the CTLA-4 gene in the association of autoimmune thyroid disease with IDDM. Diabetes 1998; 47: 125-7
-
(1998)
Diabetes
, vol.47
, pp. 125-127
-
-
Djilali-Saiah, I.1
Larger, E.2
Harfouch-Hammoud, E.3
Timsit, J.4
Clerc, J.5
Bertin, E.6
Assan, R.7
Boitard, C.8
Bach, J.F.9
Caillat-Zucman, S.10
-
30
-
-
0031750760
-
CTLA4 gene haplotypes cannot protect from IDDM in the presence of high-risk HLA DQ8 or DQ2 alleles in German families
-
Donner H, Seidl C, Braun J, Siegmund T, Herwig J, Seifried E, Usadel KH, Badenhoop K. CTLA4 gene haplotypes cannot protect from IDDM in the presence of high-risk HLA DQ8 or DQ2 alleles in German families. Diabetes 1998; 47: 1158-60
-
(1998)
Diabetes
, vol.47
, pp. 1158-1160
-
-
Donner, H.1
Seidl, C.2
Braun, J.3
Siegmund, T.4
Herwig, J.5
Seifried, E.6
Usadel, K.H.7
Badenhoop, K.8
|