Mechanistic studies of human spermine oxidase: Kinetic mechanism and pH effects

Biochemistry

Volumn 49, Issue 2, 2010, Pages 386-392

  Adachi, Mariya S ^a   Juarez, Paul R ^b   Fitzpatrick, Paul F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; AGING TIME; AMINO ACID RESIDUES; BIPHASIC; HUMAN ENZYMES; HUMAN SPERMINE OXIDASE; INITIAL VELOCITIES; KINETIC MECHANISM; LIMITING VALUES; MAMMALIAN CELLS; MECHANISTIC STUDIES; MIXING EXPERIMENTS; PROTONATED; SECOND ORDERS; SECOND-ORDER RATE CONSTANTS; SPERMIDINE; STEADY-STATE KINETICS; SUBSTRATE CONCENTRATIONS;

AMINO ACIDS; ENZYMES; MAMMALS; MECHANICS; ORGANIC ACIDS; OXYGEN; RATE CONSTANTS; REACTION INTERMEDIATES; REACTION KINETICS;

PH EFFECTS;

AMINO ACID; DIAMINE DERIVATIVE; FLAVOPROTEIN; NITROGEN; OXYGEN; QUERCETIN; SPERMINE; SPERMINE OXIDASE; UNCLASSIFIED DRUG; DNA; ENZYME INHIBITOR; OXIDOREDUCTASE; POLYAMINE OXIDASE;

ARTICLE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME KINETICS; ENZYME MECHANISM; NONHUMAN; PH; PRIORITY JOURNAL; STEADY STATE; TIME; VELOCITY; CODON; GENE EXPRESSION; GENE VECTOR; GENETICS; HUMAN; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION; PLASMID; PROTEIN BINDING;

MAMMALIA;

CODON; DNA; ENZYME INHIBITORS; GENE EXPRESSION; GENETIC VECTORS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PLASMIDS; PROTEIN BINDING; SPERMINE;

EID: 75349100932     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9017945     Document Type: Article

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