Role of cyclin inhibitor protein p21 in the inhibition of HCT116 human colon cancer cell proliferation by American ginseng (Panax quinquefolius) and its constituents

Phytomedicine

Volumn 17, Issue 3-4, 2010, Pages 261-268

  King, M L ^a   Murphy, L L ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

American ginseng; Colon cancer; Ginsenoside; HCT116 cells; P21; Polysaccharide

Indexed keywords

CASPASE 3; GINSENG EXTRACT; GINSENOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; POLYSACCHARIDE; PROTEIN BAX; PROTEIN P21; PROTEIN P53; WATER;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL COUNT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL PROLIFERATION; CELL STRAIN HCT116; CELL VIABILITY; COLON CANCER; COLON CARCINOMA; CONTROLLED STUDY; DRUG EFFECT; GINSENG; HUMAN; HUMAN CELL; PANAX QUINQUEFOLIUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GINSENOSIDES; HCT116 CELLS; HUMANS; PANAX; PHOSPHOTRANSFERASES; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; POLYSACCHARIDES; TUMOR SUPPRESSOR PROTEIN P53;

PANAX GINSENG; PANAX QUINQUEFOLIUS;

EID: 75249083418     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.06.008     Document Type: Article

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