메뉴 건너뛰기




Volumn 7, Issue 6, 2002, Pages 475-482

Oxygen deprivation induced cell death: An update

Author keywords

Anoxia; Bax; Bcl 2; Hypoxia; Mitochondria

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 9; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; BAK1 PROTEIN, HUMAN; BAX PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; MEMBRANE PROTEIN; ONCOPROTEIN;

EID: 0036889475     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020668923852     Document Type: Short Survey
Times cited : (158)

References (87)
  • 2
    • 0034625535 scopus 로고    scopus 로고
    • Apoptosis and heart failure: A critical review of the literature
    • Kang PM, Izumo S. Apoptosis and heart failure: A critical review of the literature. Circ Res 2000; 86: 1107-1113.
    • (2000) Circ Res , vol.86 , pp. 1107-1113
    • Kang, P.M.1    Izumo, S.2
  • 3
    • 0033547372 scopus 로고    scopus 로고
    • Reducing calcium overload in the ischemic brain
    • Zipfel GJ, Lee JM, Choi DW. Reducing calcium overload in the ischemic brain. N Engl J Med 1999; 341: 1543-1544.
    • (1999) N Engl J Med , vol.341 , pp. 1543-1544
    • Zipfel, G.J.1    Lee, J.M.2    Choi, D.W.3
  • 4
    • 0036548794 scopus 로고    scopus 로고
    • Dissecting tumour pathophysiology using intravital microscopy
    • Jain RK, Munn LL, Fukumura D. Dissecting tumour pathophysiology using intravital microscopy. Nature Rev Cancer 2002; 2: 266-276.
    • (2002) Nature Rev Cancer , vol.2 , pp. 266-276
    • Jain, R.K.1    Munn, L.L.2    Fukumura, D.3
  • 5
    • 0033593572 scopus 로고    scopus 로고
    • Cell death in development
    • Vaux DL, Korsmeyer SJ. Cell death in development. Cell 1999; 96: 245-254.
    • (1999) Cell , vol.96 , pp. 245-254
    • Vaux, D.L.1    Korsmeyer, S.J.2
  • 6
    • 0029893702 scopus 로고    scopus 로고
    • The origin of programmed cell death
    • Ameisen JC. The origin of programmed cell death. Science 1996; 272: 1278-1279.
    • (1996) Science , vol.272 , pp. 1278-1279
    • Ameisen, J.C.1
  • 7
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan G, Littlewood T. A matter of life and cell death. Science 1998; 281: 1317-1322.
    • (1998) Science , vol.281 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 8
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 9
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y. Caspases: Enemies within. Science 1998; 281: 1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 10
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen GS, Dixit VM. Caspases: Intracellular signaling by proteolysis. Cell 1997; 91: 443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 11
    • 0032437405 scopus 로고    scopus 로고
    • Intracellular ATP A switch in the decision between apoptosis and necrosis
    • Nicotera P, Leist M, Ferrando-May E. Intracellular ATP: A switch in the decision between apoptosis and necrosis. Toxicol Lett 1998; 102-103: 139-142.
    • (1998) Toxicol Lett , vol.102 , pp. 139-142
    • Nicotera, P.1    Leist, M.2    Ferrando-May, E.3
  • 12
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • Savill J, Fadok V. Corpse clearance defines the meaning of cell death. Nature 2000; 407: 784-788.
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 13
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995; 267: 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 14
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser A, Harris AW, Huang DC, Krammer PH, Cory S. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. Embo J 1995; 14: 6136-6147.
    • (1995) Embo J , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.3    Krammer, P.H.4    Cory, S.5
  • 15
    • 0034616946 scopus 로고    scopus 로고
    • Apoptotic pathways: Paper wraps stone blunts scissors
    • Green DR. Apoptotic pathways: Paper wraps stone blunts scissors. Cell 2000; 102: 1-4.
    • (2000) Cell , vol.102 , pp. 1-4
    • Green, D.R.1
  • 16
    • 0033258120 scopus 로고    scopus 로고
    • Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis?
    • Vander Heiden MG, Thompson CB. Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis? Nat Cell Biol 1999; 1: E209-216.
    • (1999) Nat Cell Biol , vol.1
    • Vander Heiden, M.G.1    Thompson, C.B.2
  • 17
    • 0033635733 scopus 로고    scopus 로고
    • BH3-Only proteins-essential initiators of apoptotic cell death
    • Huang DC, Strasser A. BH3-Only proteins-essential initiators of apoptotic cell death. Cell 2000; 103: 839-842.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.1    Strasser, A.2
  • 18
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 2001; 15: 2922-2933.
    • (2001) Genes Dev , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 19
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer G, Reed JC. Mitochondrial control of cell death. Nat Med 2000; 6: 513-519.
    • (2000) Nat Med , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 20
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 21
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c dependent activation of caspase-3. Cell 1997; 90: 405-413.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 22
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial prorein, that promotes cytochrome c dependent caspase activation by eliminating IAP inhibition
    • Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial prorein, that promotes cytochrome c dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102: 33-42.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 23
    • 0034710649 scopus 로고    scopus 로고
    • Structural and biochemical basis of apoptotic activation by Smac/DIABLO
    • Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 2000; 406: 855-862.
    • (2000) Nature , vol.406 , pp. 855-862
    • Chai, J.1    Du, C.2    Wu, J.W.3    Kyin, S.4    Wang, X.5    Shi, Y.6
  • 26
    • 0035957653 scopus 로고    scopus 로고
    • Pro-apoptotic Bax and Bak: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, Zong WX, Cheng EH, et al. Pro-apoptotic Bax and Bak: A requisite gateway to mitochondrial dysfunction and death. Science 2001; 292: 727-730.
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3
  • 27
    • 0034508217 scopus 로고    scopus 로고
    • The combined functions of pro-apoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
    • Lindsten T, Ross AJ, King A, et al. The combined functions of pro-apoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Mol Cell 2000; 6: 1389-1399.
    • (2000) Mol Cell , vol.6 , pp. 1389-1399
    • Lindsten, T.1    Ross, A.J.2    King, A.3
  • 28
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S, Golstein P. The Fas death factor. Science 1995; 267: 1449-1456.
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 29
    • 0033396491 scopus 로고    scopus 로고
    • Fas ligand-induced apoptosis
    • Nagata S. Fas ligand-induced apoptosis. Annu Rev Genet 1999; 33: 29-55.
    • (1999) Annu Rev Genet , vol.33 , pp. 29-55
    • Nagata, S.1
  • 30
    • 0031754828 scopus 로고    scopus 로고
    • Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis
    • Peter ME, Krammer PH. Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis. Curr Opin Immunol 1998; 10: 545-551.
    • (1998) Curr Opin Immunol , vol.10 , pp. 545-551
    • Peter, M.E.1    Krammer, P.H.2
  • 31
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer PH. CD95's deadly mission in the immune system. Nature 2000; 407: 789-795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 32
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
    • Hsu H, Xiong J, Goeddel DV. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 1995; 81: 495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 33
    • 0029026548 scopus 로고
    • FADD a novel death domain containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM. FADD, a novel death domain containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995; 81: 505-512.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 34
    • 0034660874 scopus 로고    scopus 로고
    • Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression
    • Fulda S, Meyer E, Debatin KM. Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression. Cancer Res 2000; 60: 3947-3956.
    • (2000) Cancer Res , vol.60 , pp. 3947-3956
    • Fulda, S.1    Meyer, E.2    Debatin, K.M.3
  • 36
    • 0032536771 scopus 로고    scopus 로고
    • Two CD95 (APO-1/Fas) signaling pathways
    • Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. Embo J 1998; 17: 1675-1687.
    • (1998) Embo J , vol.17 , pp. 1675-1687
    • Scaffidi, C.1    Fulda, S.2    Srinivasan, A.3
  • 37
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase-8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase-8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998; 94: 491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 38
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998; 94: 481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 47
    • 0032808154 scopus 로고    scopus 로고
    • Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria
    • Kennedy SG, Kandel ES, Cross TK, Hay N. Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria. Mol Cell Biol 1999; 19: 5800-5810.
    • (1999) Mol Cell Biol , vol.19 , pp. 5800-5810
    • Kennedy, S.G.1    Kandel, E.S.2    Cross, T.K.3    Hay, N.4
  • 48
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME. Cellular survival: A play in three Akts. Genes Dev 1999; 13: 2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 52
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3 induced phosphorylation of BAD through the protein kinase Akt
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3 induced phosphorylation of BAD through the protein kinase Akt. Science 1997; 278: 687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 54
    • 0034983918 scopus 로고    scopus 로고
    • Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
    • Gottlob K, Kennedy S, Kandel E, Robey RB, Hay N. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes and Dev 2001; 15: 1406-1418.
    • (2001) Genes and Dev , vol.15 , pp. 1406-1418
    • Gottlob, K.1    Kennedy, S.2    Kandel, E.3    Robey, R.B.4    Hay, N.5
  • 56
    • 0036510541 scopus 로고    scopus 로고
    • Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoprosis
    • Pastorino JG, Shulga N, Hoek JB. Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoprosis. J Biol Chem 2002; 277: 7610-7618.
    • (2002) J Biol Chem , vol.277 , pp. 7610-7618
    • Pastorino, J.G.1    Shulga, N.2    Hoek, J.B.3
  • 57
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • di Crisrofano A, Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell 2000; 100: 387-390.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Crisrofano, A.1    Pandolfi, P.P.2
  • 58
    • 0031870959 scopus 로고    scopus 로고
    • PTEN is essential for embryonic development and tumour suppression
    • di Cristofano A, Pesce B, Cordon-Cardo C, Pandolfi PP. PTEN is essential for embryonic development and tumour suppression. Nat Genet 1998; 19: 348-355.
    • (1998) Nat Genet , vol.19 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3    Pandolfi, P.P.4
  • 60
    • 0033534088 scopus 로고    scopus 로고
    • Adenoviral gene transfer of activated phosphatidylinositol-3′kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro
    • Matsui T, Li L, del Monte F, Fukui Y, Franke TF, Hajjar RJ, Rosenzweig A. Adenoviral gene transfer of activated phosphatidylinositol-3′kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. Circulation 1999; 100: 2373-2379.
    • (1999) Circulation , vol.100 , pp. 2373-2379
    • Matsui, T.1    Li, L.2    Del Monte, F.3    Fukui, Y.4    Franke, T.F.5    Hajjar, R.J.6    Rosenzweig, A.7
  • 62
    • 0030869787 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol-3 kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element
    • Mazure NM, Chen EY, Laderoute KR, Giaccia AJ. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol-3 kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 1997; 90: 3322-3331.
    • (1997) Blood , vol.90 , pp. 3322-3331
    • Mazure, N.M.1    Chen, E.Y.2    Laderoute, K.R.3    Giaccia, A.J.4
  • 63
    • 0034652392 scopus 로고    scopus 로고
    • Phosphatidylinositol-3 kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells
    • Jiang BH, Zheng JZ, Aoki M, Vogt PK. Phosphatidylinositol-3 kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells. Proc Natl Acad Sci USA 2000; 97: 1749-1753.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1749-1753
    • Jiang, B.H.1    Zheng, J.Z.2    Aoki, M.3    Vogt, P.K.4
  • 64
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia: A key regulatory factor in tumour growth
    • Harris AL. Hypoxia: A key regulatory factor in tumour growth. Nature Rev Cancer 2002; 2: 38-47.
    • (2002) Nature Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 65
    • 0035237410 scopus 로고    scopus 로고
    • Genetic determinants that influence hypoxia-induced apoptosis
    • Alarcon RM, Denko NC, Giaccia AJ. Genetic determinants that influence hypoxia-induced apoptosis. Novartis Found Symp 2001; 240: 115-128.
    • (2001) Novartis Found Symp , vol.240 , pp. 115-128
    • Alarcon, R.M.1    Denko, N.C.2    Giaccia, A.J.3
  • 66
    • 0035206383 scopus 로고    scopus 로고
    • Mechanisms of p53 dependent apoptosis
    • Schuler M, Green DR. Mechanisms of p53 dependent apoptosis. Biochem Soc Trans 2001; 29: 684-688.
    • (2001) Biochem Soc Trans , vol.29 , pp. 684-688
    • Schuler, M.1    Green, D.R.2
  • 67
    • 0028110809 scopus 로고
    • Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low oxygen conditions is independent of p53 status
    • Graeber TG, Peterson JF, Tsai M, Monica K, Fornace AJ, Jr, Giaccia AJ. Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low oxygen conditions is independent of p53 status. Mol Cell Biol 1994; 14: 6264-6277.
    • (1994) Mol Cell Biol , vol.14 , pp. 6264-6277
    • Graeber, T.G.1    Peterson, J.F.2    Tsai, M.3    Monica, K.4    Fornace A.J., Jr.5    Giaccia, A.J.6
  • 69
    • 0035910385 scopus 로고    scopus 로고
    • Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells
    • Sansome C, Zaika A, Marchenko ND, Moll UM. Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells. FEBS Lett 2001; 488: 110-115.
    • (2001) FEBS Lett , vol.488 , pp. 110-115
    • Sansome, C.1    Zaika, A.2    Marchenko, N.D.3    Moll, U.M.4
  • 70
    • 0031918244 scopus 로고    scopus 로고
    • Regulation of proliferation-survival decisions during tumor cell hypoxia
    • Schmaltz C, Hardenbergh PH, Wells A, Fisher DE. Regulation of proliferation-survival decisions during tumor cell hypoxia. Mol Cell Biol 1998; 18: 2845-2854.
    • (1998) Mol Cell Biol , vol.18 , pp. 2845-2854
    • Schmaltz, C.1    Hardenbergh, P.H.2    Wells, A.3    Fisher, D.E.4
  • 72
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor-1
    • 2 homeostasis by hypoxia-inducible factor-1. Annu Rev Cell Dev Biol 1999; 15: 551-578.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 73
    • 0034255036 scopus 로고    scopus 로고
    • Expression of the gene encoding the pro-apoptotic Nip3 protein is induced by hypoxia
    • Bruick RK. Expression of the gene encoding the pro-apoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 2000; 97: 9082-9087.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9082-9087
    • Bruick, R.K.1
  • 74
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1 dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL. HIF-1 dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 2001; 61: 6669-6673.
    • (2001) Cancer Res , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3    Greenberg, A.H.4    Harris, A.L.5
  • 79
    • 0035418621 scopus 로고    scopus 로고
    • Constitutive expression of hypoxia inducible factor-1α renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
    • Akakura N, Kobayashi M, Horiuchi I, Suzuki A, Wang J, Chen J, Niizeki H, Kawamura KI, Hosokawa M, Asaka M. Constitutive expression of hypoxia inducible factor-1α renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res 2001; 61: 6548-6554.
    • (2001) Cancer Res , vol.61 , pp. 6548-6554
    • Akakura, N.1    Kobayashi, M.2    Horiuchi, I.3    Suzuki, A.4    Wang, J.5    Chen, J.6    Niizeki, H.7    Kawamura, K.I.8    Hosokawa, M.9    Asaka, M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.