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Volumn 16, Issue 1, 2010, Pages 62-68

Pharmacological treatments for acute respiratory distress syndrome

Author keywords

Acute respiratory distress syndrome; Alveolar clotting; Corticosteroids; Neutrophil elastase inhibitor; Surfactant

Indexed keywords

ALMITRINE; ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALFACTANT; CORTICOSTEROID; DROTRECOGIN; LEUKOCYTE ELASTASE INHIBITOR; LUSUPULTIDE; NEUROMUSCULAR BLOCKING AGENT; NITRIC OXIDE; PLACEBO; PROSTACYCLIN; RECOMBINANT BLOOD CLOTTING FACTOR 7A; SALBUTAMOL; SIVELESTAT; SURFACTANT; TISSUE FACTOR PATHWAY INHIBITOR; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; VASODILATOR AGENT;

EID: 75149161667     PISSN: 10705295     EISSN: 15317072     Source Type: Journal    
DOI: 10.1097/MCC.0b013e328334b151     Document Type: Review
Times cited : (43)

References (85)
  • 1
    • 0034604129 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000; 342:1334-1349.
    • (2000) N Engl J Med , vol.342 , pp. 1334-1349
    • Ware, L.B.1    Matthay, M.A.2
  • 2
    • 0032911805 scopus 로고    scopus 로고
    • The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome
    • Pugin J, Verghese G, Widmer M-C, Matthay MA. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit Care Med 1999; 27:304-312.
    • (1999) Crit Care Med , vol.27 , pp. 304-312
    • Pugin, J.1    Verghese, G.2    Widmer, M.-C.3    Matthay, M.A.4
  • 3
    • 0034993527 scopus 로고    scopus 로고
    • Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome
    • Ware LB, Matthay MA. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Resp Crit Care Med 2001; 163:1376-1383.
    • (2001) Am J Resp Crit Care Med , vol.163 , pp. 1376-1383
    • Ware, L.B.1    Matthay, M.A.2
  • 4
    • 0022549234 scopus 로고
    • Neutrophil-mediated injury to endothelial cells: Enhancement by endotoxin and essential role of neutrophil elastase
    • Smedly LA, Tonnesen MG, Sandhaus RA, et al. Neutrophil-mediated injury to endothelial cells: enhancement by endotoxin and essential role of neutrophil elastase. J Clin Invest 1986; 77:1233-1243.
    • (1986) J Clin Invest , vol.77 , pp. 1233-1243
    • Smedly, L.A.1    Tonnesen, M.G.2    Sandhaus, R.A.3
  • 5
    • 0022928082 scopus 로고
    • O2 metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs
    • Baird BR, Cheronis JC, Sandhaus RA, et al. O2 metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs. J Appl Physiol 1986; 61:2224-2229.
    • (1986) J Appl Physiol , vol.61 , pp. 2224-2229
    • Baird, B.R.1    Cheronis, J.C.2    Sandhaus, R.A.3
  • 6
    • 0036250774 scopus 로고    scopus 로고
    • Neutrophil elastase and acute lung injury: Prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics
    • Zeiher BG, Matsuoka S, Kawabata K, Repine JE. Neutrophil elastase and acute lung injury: prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics. Crit Care Med 2002; 30 (Suppl):S281-S287.
    • (2002) Crit Care Med , vol.30 , Issue.SUPPL.
    • Zeiher, B.G.1    Matsuoka, S.2    Kawabata, K.3    Repine, J.E.4
  • 7
    • 0022620180 scopus 로고
    • Lung neutrophils in the adult respiratory distress syndrome: Clinical and pathophysiological significance
    • Weiland JE, Davis WB, Holter JF, et al. Lung neutrophils in the adult respiratory distress syndrome: clinical and pathophysiological significance. Am Rev Resp Dis 1986; 133:218-225.
    • (1986) Am Rev Resp Dis , vol.133 , pp. 218-225
    • Weiland, J.E.1    Davis, W.B.2    Holter, J.F.3
  • 8
    • 0026401002 scopus 로고
    • Protease mechanisms in the pathogenesis of acute lung injury
    • Petty T. Protease mechanisms in the pathogenesis of acute lung injury. Ann NY Acad Sci 1991; 624:267-277.
    • (1991) Ann NY Acad Sci , vol.624 , pp. 267-277
    • Petty, T.1
  • 9
    • 0028243988 scopus 로고
    • Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome
    • Steinberg KP, Milberg JA, Martin TR, et al. Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome. Am J Respir Crit Care Med 1994; 150:113-122.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 113-122
    • Steinberg, K.P.1    Milberg, J.A.2    Martin, T.R.3
  • 10
    • 17644440915 scopus 로고    scopus 로고
    • Serial changes in surfactantassociated proteins in lung and serum before and after onset of ARDS
    • Greene KE, Wright JR, Steinberg KP, et al. Serial changes in surfactantassociated proteins in lung and serum before and after onset of ARDS. Am J Respir Crit Care Med 1999; 160:1843-1850.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1843-1850
    • Greene, K.E.1    Wright, J.R.2    Steinberg, K.P.3
  • 11
    • 0026337716 scopus 로고
    • Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome
    • Gregory TJ, Longmore WJ, MoxleyMA, et al. Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J Clin Invest 1991; 88:1967-1981.
    • (1991) J Clin Invest , vol.88 , pp. 1967-1981
    • Gregory, T.J.1    Longmore, W.J.2    Moxley, M.A.3
  • 12
    • 0037794407 scopus 로고    scopus 로고
    • Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant
    • Spragg RG, Lewis JF, Wurst W, et al. Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant. Am J Respir Crit Care Med 2003; 167:1562-1566.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1562-1566
    • Spragg, R.G.1    Lewis, J.F.2    Wurst, W.3
  • 13
    • 0020636569 scopus 로고
    • The pulmonary vascular lesions of the adult respiratory distress syndrome
    • Tomashefski JF Jr, Davies P, Boggis C, et al. The pulmonary vascular lesions of the adult respiratory distress syndrome. Am J Pathol 1983; 112:112-126.
    • (1983) Am J Pathol , vol.112 , pp. 112-126
    • Tomashefski Jr., J.F.1    Davies, P.2    Boggis, C.3
  • 14
    • 33748423391 scopus 로고    scopus 로고
    • Bench to bedside: Targeting coagulation and fibrinolysis in acute lung injury
    • Ware LB, Camerer E, Welty-Wolf K, et al. Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury. Am J Physiol Lung Cell Mol Physiol 2006; 291:L307-L311.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291
    • Ware, L.B.1    Camerer, E.2    Welty-Wolf, K.3
  • 15
    • 0033796308 scopus 로고    scopus 로고
    • Pulmonary pathology of acute respiratory distress syndrome
    • Tomashefski JF Jr. Pulmonary pathology of acute respiratory distress syndrome. Clin Chest Med 2000; 21:436-466.
    • (2000) Clin Chest Med , vol.21 , pp. 436-466
    • Tomashefski Jr., J.F.1
  • 16
    • 34247231131 scopus 로고    scopus 로고
    • Methylprednisolone infusion in early severe ARDS
    • Meduri GU, Golden E, Freire AX, et al. Methylprednisolone infusion in early severe ARDS. Chest 2007; 131:954-963.
    • (2007) Chest , vol.131 , pp. 954-963
    • Meduri, G.U.1    Golden, E.2    Freire, A.X.3
  • 17
    • 0023549919 scopus 로고
    • High dose corticosteroids in patients with adult respiratory distress syndrome
    • Bernard G, Luce J, Sprung C, et al. High dose corticosteroids in patients with adult respiratory distress syndrome. N Engl J Med 1987; 317:1565-1570.
    • (1987) N Engl J Med , vol.317 , pp. 1565-1570
    • Bernard, G.1    Luce, J.2    Sprung, C.3
  • 19
    • 0023576134 scopus 로고
    • Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome
    • Bone RC, Fisher CJ Jr, Clemmer TP, et al. Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome. Chest 1987; 92:1032-1036.
    • (1987) Chest , vol.92 , pp. 1032-1036
    • Bone, R.C.1    Fisher Jr., C.J.2    Clemmer, T.P.3
  • 20
    • 0023713254 scopus 로고
    • Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock
    • Luce J, Montgomery A, Marks J, et al. Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock. Am Rev Respir Dis 1988; 138:62-68.
    • (1988) Am Rev Respir Dis , vol.138 , pp. 62-68
    • Luce, J.1    Montgomery, A.2    Marks, J.3
  • 21
    • 0021832096 scopus 로고
    • Idiopathic pulmonary fibrosis in adult respiratory distress syndrome: Diagnosis and treatment
    • Ashbaugh DG, Maier RV. Idiopathic pulmonary fibrosis in adult respiratory distress syndrome: diagnosis and treatment. Arch Surg 1985; 120:530-535.
    • (1985) Arch Surg , vol.120 , pp. 530-535
    • Ashbaugh, D.G.1    Maier, R.V.2
  • 22
    • 0028845467 scopus 로고
    • Are corticosteroids salvage therapy for refractory acute respiratory distress syndrome?
    • Biffl WL, Moore FA, Moore EE, et al. Are corticosteroids salvage therapy for refractory acute respiratory distress syndrome? Am J Surg 1995; 170:591-596.
    • (1995) Am J Surg , vol.170 , pp. 591-596
    • Biffl, W.L.1    Moore, F.A.2    Moore, E.E.3
  • 23
    • 0025141831 scopus 로고
    • Established ARDS treated with a sustained course of adrenocortical steroids
    • Hooper RG, Kearl RA. Established ARDS treated with a sustained course of adrenocortical steroids. Chest 1990; 97:138-143.
    • (1990) Chest , vol.97 , pp. 138-143
    • Hooper, R.G.1    Kearl, R.A.2
  • 24
    • 0026655416 scopus 로고
    • Chronic adult respiratory distress syndrome: A role for corticosteroids?
    • Braude S, Haslam P, Hughes D, et al. Chronic adult respiratory distress syndrome: a role for corticosteroids? Crit Care Med 1992; 20:1187-1189.
    • (1992) Crit Care Med , vol.20 , pp. 1187-1189
    • Braude, S.1    Haslam, P.2    Hughes, D.3
  • 25
    • 0031714022 scopus 로고    scopus 로고
    • Established acute respiratory distress syndrome: Benefit of corticosteroid rescue therapy
    • Keel JB, Hauser M, Stocker R, et al. Established acute respiratory distress syndrome: benefit of corticosteroid rescue therapy. Respiration 1998; 65:258-264.
    • (1998) Respiration , vol.65 , pp. 258-264
    • Keel, J.B.1    Hauser, M.2    Stocker, R.3
  • 26
    • 0026075985 scopus 로고
    • Fibroproliferative phase of ARDS: Clinical findings and effects of corticosteroids
    • Meduri GU, Belenchia JM, Estes RJ, et al. Fibroproliferative phase of ARDS: clinical findings and effects of corticosteroids. Chest 1991; 100:943-952.
    • (1991) Chest , vol.100 , pp. 943-952
    • Meduri, G.U.1    Belenchia, J.M.2    Estes, R.J.3
  • 27
    • 0032496894 scopus 로고    scopus 로고
    • Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: A randomized controlled trial
    • Meduri GU, Headley AS, Golden E, et al. Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial. J Am Med Assoc 1998; 280:159-165.
    • (1998) J Am Med Assoc , vol.280 , pp. 159-165
    • Meduri, G.U.1    Headley, A.S.2    Golden, E.3
  • 28
    • 33645865234 scopus 로고    scopus 로고
    • Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome
    • Steinberg K, Hudson L, Goodman R, et al. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med 2006; 354:1671-1684.
    • (2006) N Engl J Med , vol.354 , pp. 1671-1684
    • Steinberg, K.1    Hudson, L.2    Goodman, R.3
  • 29
    • 34250763692 scopus 로고    scopus 로고
    • Do glucocorticoids decrease mortality in acute respiratory distress syndrome? A meta-analysis
    • Agarwal R, Nath A, Aggarwal AN, Gupta D. Do glucocorticoids decrease mortality in acute respiratory distress syndrome? A meta-analysis. Respirology 2007; 12:585-590.
    • (2007) Respirology , vol.12 , pp. 585-590
    • Agarwal, R.1    Nath, A.2    Aggarwal, A.N.3    Gupta, D.4
  • 30
    • 38349070821 scopus 로고    scopus 로고
    • Steroid treatment in ARDS: A critical appraisal of the ARDS network trial and the recent literature
    • Meduri GU, Marik PE, Chrousos GP, et al. Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature. Intensive Care Med 2008; 34:61-69.
    • (2008) Intensive Care Med , vol.34 , pp. 61-69
    • Meduri, G.U.1    Marik, P.E.2    Chrousos, G.P.3
  • 31
    • 43249117658 scopus 로고    scopus 로고
    • Corticosteroids in the prevention and treatment of acute respiratory distress syndrome (ARDS) in adults: Metaanalysis
    • Peter JV, John P, Graham PL, et al. Corticosteroids in the prevention and treatment of acute respiratory distress syndrome (ARDS) in adults: metaanalysis. Br Med J 2008; 336:1006-1009.
    • (2008) Br Med J , vol.336 , pp. 1006-1009
    • Peter, J.V.1    John, P.2    Graham, P.L.3
  • 32
    • 67650495796 scopus 로고    scopus 로고
    • Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: A systematic review and metaanalysis
    • Tang BMP, Craig JC, Eslick GD, et al. Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: a systematic review and metaanalysis. Crit Care Med 2009; 37:1594-1603.
    • (2009) Crit Care Med , vol.37 , pp. 1594-1603
    • Tang, B.M.P.1    Craig, J.C.2    Eslick, G.D.3
  • 33
    • 12244305569 scopus 로고    scopus 로고
    • Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury
    • Parsons PE, Eisner MD, Thompson BT, et al. Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med 2005; 33:1-6.
    • (2005) Crit Care Med , vol.33 , pp. 1-6
    • Parsons, P.E.1    Eisner, M.D.2    Thompson, B.T.3
  • 34
    • 0345436055 scopus 로고    scopus 로고
    • Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome
    • Ranieri VM, Suter PM, Tortorella C, et al. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome. J Am Med Assoc 1999; 282:54-61.
    • (1999) J Am Med Assoc , vol.282 , pp. 54-61
    • Ranieri, V.M.1    Suter, P.M.2    Tortorella, C.3
  • 35
    • 67651011893 scopus 로고    scopus 로고
    • Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: A multicentre randomised controlled trial
    • Jabre P, Combes X, Lapostolle F, et al. Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial. Lancet 2009; 374:293-300.
    • (2009) Lancet , vol.374 , pp. 293-300
    • Jabre, P.1    Combes, X.2    Lapostolle, F.3
  • 37
    • 61449219064 scopus 로고    scopus 로고
    • Paralytics in critical care: Not always that bad guy
    • Forel JM, Roch A, Papazian L. Paralytics in critical care: not always that bad guy. Curr Opin Crit Care 2009; 15:59-66.
    • (2009) Curr Opin Crit Care , vol.15 , pp. 59-66
    • Forel, J.M.1    Roch, A.2    Papazian, L.3
  • 38
    • 75149175185 scopus 로고    scopus 로고
    • Systematic two-day muscle relaxants course in the early phase of severe acute respiratory distress syndrome. A multicenter randomized controlled trial
    • Papazian L, Forel JM, Gacouin A, et al. Systematic two-day muscle relaxants course in the early phase of severe acute respiratory distress syndrome. A multicenter randomized controlled trial. Intensive Care Med 2009; 35:S6.
    • (2009) Intensive Care Med , vol.35
    • Papazian, L.1    Forel, J.M.2    Gacouin, A.3
  • 39
    • 44249087880 scopus 로고    scopus 로고
    • Neutrophil elastase activity in acute lung injury and respiratory distress syndrome
    • Hashimoto S, Okayama Y, Shime N, et al. Neutrophil elastase activity in acute lung injury and respiratory distress syndrome. Respirology 2008; 13:581-584.
    • (2008) Respirology , vol.13 , pp. 581-584
    • Hashimoto, S.1    Okayama, Y.2    Shime, N.3
  • 40
    • 31144454915 scopus 로고    scopus 로고
    • Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome
    • Okayama N, Kakihana Y, Setoguchi D, et al. Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome. J Anesth 2006; 20:6-10.
    • (2006) J Anesth , vol.20 , pp. 6-10
    • Okayama, N.1    Kakihana, Y.2    Setoguchi, D.3
  • 41
    • 3943106162 scopus 로고    scopus 로고
    • Neutrophil elastase inhibition in acute lung injury: Results of the STRIVE study
    • Zeiher BG, Artigas A, Vincent JL, et al. Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study. Crit Care Med 2004; 32:1695-1702.
    • (2004) Crit Care Med , vol.32 , pp. 1695-1702
    • Zeiher, B.G.1    Artigas, A.2    Vincent, J.L.3
  • 42
    • 0017333439 scopus 로고
    • Pulmonary hypertension in severe acute respiratory failure
    • Zapol WM, Snider MT. Pulmonary hypertension in severe acute respiratory failure. N Engl J Med 1977; 296:476-480.
    • (1977) N Engl J Med , vol.296 , pp. 476-480
    • Zapol, W.M.1    Snider, M.T.2
  • 43
    • 0020451722 scopus 로고
    • Pulmonary vascular remodeling in adult respiratory distress syndrome
    • Snow RL, Davies P, Pontoppidan H, et al. Pulmonary vascular remodeling in adult respiratory distress syndrome. Am Rev Respir Dis 1982; 126:887-892.
    • (1982) Am Rev Respir Dis , vol.126 , pp. 887-892
    • Snow, R.L.1    Davies, P.2    Pontoppidan, H.3
  • 44
    • 0037171703 scopus 로고    scopus 로고
    • Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome
    • Nuckton TJ, Alonso JA, Kallet RH, et al. Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 2002; 346:1281-1286.
    • (2002) N Engl J Med , vol.346 , pp. 1281-1286
    • Nuckton, T.J.1    Alonso, J.A.2    Kallet, R.H.3
  • 45
    • 58549083739 scopus 로고    scopus 로고
    • Incidence and prognostic value of right ventricular failure in acute respiratory distress syndrome
    • Osman D,Monnet X, Castelain V, et al. Incidence and prognostic value of right ventricular failure in acute respiratory distress syndrome. Intensive Care Med 2009; 35:69-76.
    • (2009) Intensive Care Med , vol.35 , pp. 69-76
    • Osman, D.1    Monnet, X.2    Castelain, V.3
  • 46
    • 33644598461 scopus 로고    scopus 로고
    • Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia-a review
    • Schultz MJ, Haitsma JJ, Zhang H, Slutsky AS. Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia-a review. Crit Care Med 2006; 34:871-877.
    • (2006) Crit Care Med , vol.34 , pp. 871-877
    • Schultz, M.J.1    Haitsma, J.J.2    Zhang, H.3    Slutsky, A.S.4
  • 47
    • 34447294235 scopus 로고    scopus 로고
    • The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor
    • Bastarache J, Wang L, Geiser T, et al. The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor. Thorax 2007; 62:608-616.
    • (2007) Thorax , vol.62 , pp. 608-616
    • Bastarache, J.1    Wang, L.2    Geiser, T.3
  • 48
    • 34247216695 scopus 로고    scopus 로고
    • Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation
    • Wang L, Bastarache J, Wickersham N, et al. Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation. Am J Respir Cell Mol Biol 2007; 36:497-503.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 497-503
    • Wang, L.1    Bastarache, J.2    Wickersham, N.3
  • 49
    • 66449108092 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled, dose-escalation trial assessing safety and efficacy of active site inactivated recombinant factor VIIa in subjects with acute lung injury or acute respiratory distress syndrome
    • Vincent JL, Artigas A, Petersen LC, Meyer C. A multicenter, randomized, double-blind, placebo-controlled, dose-escalation trial assessing safety and efficacy of active site inactivated recombinant factor VIIa in subjects with acute lung injury or acute respiratory distress syndrome. Crit Care Med 2009; 37:1874-1880.
    • (2009) Crit Care Med , vol.37 , pp. 1874-1880
    • Vincent, J.L.1    Artigas, A.2    Petersen, L.C.3    Meyer, C.4
  • 50
    • 45849105171 scopus 로고    scopus 로고
    • Intra-alveolar tissue factor pathway inhibitor is not sufficient to block tissue factor procoagulant activity
    • Bastarache JA, Wang L, Wang Z, et al. Intra-alveolar tissue factor pathway inhibitor is not sufficient to block tissue factor procoagulant activity. Am J Physiol Lung Cell Mol Physiol 2008; 294:L874-881.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Bastarache, J.A.1    Wang, L.2    Wang, Z.3
  • 51
    • 0035159740 scopus 로고    scopus 로고
    • Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study
    • Abraham E, Reinhart K, Svoboda P, et al. Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: a multicenter, randomized, placebo-controlled, single-blind, dose escalation study. Crit Care Med 2001; 29:2081-2089.
    • (2001) Crit Care Med , vol.29 , pp. 2081-2089
    • Abraham, E.1    Reinhart, K.2    Svoboda, P.3
  • 52
    • 0035826096 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709.
    • (2001) N Engl J Med , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.2    Laterre, P.F.3
  • 53
    • 0037803423 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: Data from the PROWESS trial
    • Dhainaut JF, Laterre PF, Janes JM, et al. Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial. Intensive Care Med 2003; 29:894-903.
    • (2003) Intensive Care Med , vol.29 , pp. 894-903
    • Dhainaut, J.F.1    Laterre, P.F.2    Janes, J.M.3
  • 54
    • 21044431893 scopus 로고    scopus 로고
    • Severe community-acquired pneumonia as a cause of severe sepsis: Data from the PROWESS study
    • Laterre PF, Garber G, Levy H, et al. Severe community-acquired pneumonia as a cause of severe sepsis: data from the PROWESS study. Crit Care Med 2005; 33:952-961.
    • (2005) Crit Care Med , vol.33 , pp. 952-961
    • Laterre, P.F.1    Garber, G.2    Levy, H.3
  • 55
    • 51849153326 scopus 로고    scopus 로고
    • Randomized clinical trial of activated protein C for the treatment of acute lung injury
    • Liu KD, Levitt J, Zhuo H, et al. Randomized clinical trial of activated protein C for the treatment of acute lung injury. Am J Respir Crit Care Med 2008; 178:618-623.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 618-623
    • Liu, K.D.1    Levitt, J.2    Zhuo, H.3
  • 56
    • 0031746880 scopus 로고    scopus 로고
    • Inhaled nitric oxide in acute respiratory distress syndrome: A pilot randomized controlled study
    • Troncy E, Collet JP, Shapiro S, et al. Inhaled nitric oxide in acute respiratory distress syndrome: a pilot randomized controlled study. Am J Respir Crit Care Med 1998; 157:1483-1488.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1483-1488
    • Troncy, E.1    Collet, J.P.2    Shapiro, S.3
  • 57
    • 0031975630 scopus 로고    scopus 로고
    • Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: Results of a randomized phase II trial
    • Dellinger RP, Zimmerman JL, Taylor RW, et al. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Crit Care Med 1998; 26:15-23.
    • (1998) Crit Care Med , vol.26 , pp. 15-23
    • Dellinger, R.P.1    Zimmerman, J.L.2    Taylor, R.W.3
  • 58
    • 1842433745 scopus 로고    scopus 로고
    • Low-dose inhaled nitric oxide in patients with acute lung injury: A randomized controlled trial
    • Taylor RW, Zimmerman JL, Dellinger RP, et al. Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial. J Am Med Assoc 2004; 291:1603-1609.
    • (2004) J Am Med Assoc , vol.291 , pp. 1603-1609
    • Taylor, R.W.1    Zimmerman, J.L.2    Dellinger, R.P.3
  • 59
    • 3643073477 scopus 로고    scopus 로고
    • Inhalation of nitric oxide in acute lung injury: Results of a European multicentre study
    • Lundin S, Mang H, Smithies M, et al. Inhalation of nitric oxide in acute lung injury: results of a European multicentre study. Intensive Care Med 1999; 25:911-919.
    • (1999) Intensive Care Med , vol.25 , pp. 911-919
    • Lundin, S.1    Mang, H.2    Smithies, M.3
  • 60
    • 34247468559 scopus 로고    scopus 로고
    • Effect of nitric oxide on oxygenation and mortality in acute lung injury: Systematic review and metaanalysis
    • Adhikari NKJ, Burns KEA, Friedrich JO, et al. Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and metaanalysis. Br Med J 2007; 334:779-786.
    • (2007) Br Med J , vol.334 , pp. 779-786
    • Adhikari, N.K.J.1    Burns, K.E.A.2    Friedrich, J.O.3
  • 61
    • 0023899977 scopus 로고
    • Effect of almitrine on ventilationperfusion distribution in adult respiratory distress syndrome
    • Reyes A, Roca J, Rodriguez-Roisin R, et al. Effect of almitrine on ventilationperfusion distribution in adult respiratory distress syndrome. Am Rev Respir Dis 1988; 137:1062-1067.
    • (1988) Am Rev Respir Dis , vol.137 , pp. 1062-1067
    • Reyes, A.1    Roca, J.2    Rodriguez-Roisin, R.3
  • 62
    • 0032447320 scopus 로고    scopus 로고
    • Intravenous almitrine combined with inhaled nitric oxide for acute respiratory distress syndrome
    • Gallart L, Lu Q, Puybasset L, et al. Intravenous almitrine combined with inhaled nitric oxide for acute respiratory distress syndrome. Am J Respir Crit Care Med 1998; 158:1770-1777.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1770-1777
    • Gallart, L.1    Lu, Q.2    Puybasset, L.3
  • 63
    • 0032798016 scopus 로고    scopus 로고
    • Inhaled nitric oxide and vasoconstrictors in acute respiratory distress syndrome
    • Papazian L, Roch A, Bregeon F, et al. Inhaled nitric oxide and vasoconstrictors in acute respiratory distress syndrome. Am J Respir Crit Care Med 1999; 160:473-479.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 473-479
    • Papazian, L.1    Roch, A.2    Bregeon, F.3
  • 64
    • 0030339154 scopus 로고    scopus 로고
    • Inhaled prostacyclin (PGI2) versus inhaled nitric oxide in adult respiratory distress syndrome
    • Zwissler B, Kemming G, Habler O, et al. Inhaled prostacyclin (PGI2) versus inhaled nitric oxide in adult respiratory distress syndrome. Am J Respir Crit Care Med 1996; 154:1671-1677.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 1671-1677
    • Zwissler, B.1    Kemming, G.2    Habler, O.3
  • 65
    • 0029880173 scopus 로고    scopus 로고
    • Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome
    • Walmrath D, Schneider T, Schermuly R, et al. Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome. Am J Respir Crit Care Med 1996; 153:991-996.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 991-996
    • Walmrath, D.1    Schneider, T.2    Schermuly, R.3
  • 66
    • 9344262898 scopus 로고    scopus 로고
    • Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome
    • Anzueto A, Baughman RP, Guntupalli KK, et al. Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome. N Engl J Med 1996; 334:1417-1421.
    • (1996) N Engl J Med , vol.334 , pp. 1417-1421
    • Anzueto, A.1    Baughman, R.P.2    Guntupalli, K.K.3
  • 67
    • 19944431657 scopus 로고    scopus 로고
    • Effect of exogenous surfactant (calfactant) in pediatric acute lung injury: A randomized controlled trial
    • Willson DF, Thomas NJ, Markovitz BP, et al. Effect of exogenous surfactant (calfactant) in pediatric acute lung injury: a randomized controlled trial. J Am Med Assoc 2005; 293:470-476.
    • (2005) J Am Med Assoc , vol.293 , pp. 470-476
    • Willson, D.F.1    Thomas, N.J.2    Markovitz, B.P.3
  • 68
    • 4143067903 scopus 로고    scopus 로고
    • Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome
    • Spragg RG, Lewis JF, Walmrath HD, et al. Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome. N Engl J Med 2004; 351:884-892.
    • (2004) N Engl J Med , vol.351 , pp. 884-892
    • Spragg, R.G.1    Lewis, J.F.2    Walmrath, H.D.3
  • 69
    • 54249160122 scopus 로고    scopus 로고
    • A search for subgroups of patients with ARDS who may benefit from surfactant replacement therapy: A pooled analysis of five studies with recombinant surfactant protein-C surfactant (Venticute)
    • Taut FJH, Rippin G, Schenk P, et al. A search for subgroups of patients with ARDS who may benefit from surfactant replacement therapy: a pooled analysis of five studies with recombinant surfactant protein-C surfactant (Venticute). Chest 2008; 134:724-732.
    • (2008) Chest , vol.134 , pp. 724-732
    • Taut, F.J.H.1    Rippin, G.2    Schenk, P.3
  • 70
    • 3142721744 scopus 로고    scopus 로고
    • Clinical relevant concentrations of b2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury
    • McAuley DF, Frank JA, Fang X, Matthay MA. Clinical relevant concentrations of b2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate- dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury. Crit Care Med 2004; 32:1470-1476.
    • (2004) Crit Care Med , vol.32 , pp. 1470-1476
    • McAuley, D.F.1    Frank, J.A.2    Fang, X.3    Matthay, M.A.4
  • 71
    • 0037162097 scopus 로고    scopus 로고
    • Salmeterol for the prevention of high altitude pulmonary edema
    • Saroti C, Allemann Y, Duplain H, et al. Salmeterol for the prevention of highaltitude pulmonary edema. N Engl J Med 2002; 346:1631-1636.
    • (2002) N Engl J Med , vol.346 , pp. 1631-1636
    • Saroti, C.1    Allemann, Y.2    Duplain, H.3
  • 72
    • 32144437063 scopus 로고    scopus 로고
    • The b-agonist lung injury trial (BALTI): A randomized placebo-controlled clinical trial
    • Perkins GD, McAuley DF, Thickett DR, Gao F. The b-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial. Am J Respir Crit Care Med 2006; 173:281-287.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 281-287
    • Perkins, G.D.1    McAuley, D.F.2    Thickett, D.R.3    Gao, F.4
  • 73
    • 40649106983 scopus 로고    scopus 로고
    • In vivo and in vitro effects of salbutamol on alveolar epithelial repair in acute lung injury
    • Perkins GD, Gao F, Thickett DR. In vivo and in vitro effects of salbutamol on alveolar epithelial repair in acute lung injury. Thorax 2008; 63:215-220.
    • (2008) Thorax , vol.63 , pp. 215-220
    • Perkins, G.D.1    Gao, F.2    Thickett, D.R.3
  • 74
    • 67649766886 scopus 로고    scopus 로고
    • Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome
    • O'Kane CM, McKeown SW, PerkinsGD, et al. Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome. Crit Care Med 2009; 37:2242-2249.
    • (2009) Crit Care Med , vol.37 , pp. 2242-2249
    • O'Kane, C.M.1    McKeown, S.W.2    Perkins, G.D.3
  • 75
    • 73249115212 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of an aerosolized beta-2 adrenergic agonist (albuterol) for the treatment of acute lung injury
    • Matthay MA, Brower R, Thompson BT, et al. Randomized, placebo-controlled trial of an aerosolized beta-2 adrenergic agonist (albuterol) for the treatment of acute lung injury. Am J Respir Crit Care Med 2009; 179:A2166.
    • (2009) Am J Respir Crit Care Med , vol.179
    • Matthay, M.A.1    Brower, R.2    Thompson, B.T.3
  • 77
    • 4644340839 scopus 로고    scopus 로고
    • Comparison of clinical criteria for the acute respiratory distress syndrome with autopsy findings
    • Esteban A, Fernández-Segoviano P, Frutos-Vivar F, et al. Comparison of clinical criteria for the acute respiratory distress syndrome with autopsy findings. Ann Intern Med 2004; 141:440-445.
    • (2004) Ann Intern Med , vol.141 , pp. 440-445
    • Esteban, A.1    Fernández-Segoviano, P.2    Frutos-Vivar, F.3
  • 78
    • 34748870199 scopus 로고    scopus 로고
    • Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders
    • Calfee CS, Eisner MD, Ware LB, et al. Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med 2007; 35:2243-2250.
    • (2007) Crit Care Med , vol.35 , pp. 2243-2250
    • Calfee, C.S.1    Eisner, M.D.2    Ware, L.B.3
  • 79
    • 0031819513 scopus 로고    scopus 로고
    • Acute respiratory distress syndrome caused by pulmonary and extrapulmonary disease: Different syndromes?
    • Gattinoni L, Pelosi P, Suter PM, et al. Acute respiratory distress syndrome caused by pulmonary and extrapulmonary disease: different syndromes? Am J Respir Crit Care Med 1998; 158:3-11.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 3-11
    • Gattinoni, L.1    Pelosi, P.2    Suter, P.M.3
  • 80
    • 0031790603 scopus 로고    scopus 로고
    • Procollagen types i and III aminoterminal propeptide levels during acute respiratory distress syndrome and in response to methylprednisolone treatment
    • Meduri GU, Tolley EA, Chinn A, et al. Procollagen types I and III aminoterminal propeptide levels during acute respiratory distress syndrome and in response to methylprednisolone treatment. Am J Respir Crit Care Med 1998; 158: 1432-1441.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1432-1441
    • Meduri, G.U.1    Tolley, E.A.2    Chinn, A.3
  • 81
    • 0035671508 scopus 로고    scopus 로고
    • Von Willebrand factor antigen is an independent marker of poor outcome in patients with early acute lung injury
    • Ware LB, Conner ER, Matthay MA. Von Willebrand factor antigen is an independent marker of poor outcome in patients with early acute lung injury. Crit Care Med 2001; 29:2325-2331.
    • (2001) Crit Care Med , vol.29 , pp. 2325-2331
    • Ware, L.B.1    Conner, E.R.2    Matthay, M.A.3
  • 82
    • 34547689307 scopus 로고    scopus 로고
    • Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome
    • Ware LB, Matthay MA, Parsons PE, et al. Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome. Crit Care Med 2007; 35:1821-1828.
    • (2007) Crit Care Med , vol.35 , pp. 1821-1828
    • Ware, L.B.1    Matthay, M.A.2    Parsons, P.E.3
  • 83
    • 33846649530 scopus 로고    scopus 로고
    • Alveolar recruitment in pulmonary and extrapulmonary acute respiratory distress syndrome: Comparison using pressure-volume curve or static compliance
    • Thille AW, Richard JCM, Maggiore SM, et al. Alveolar recruitment in pulmonary and extrapulmonary acute respiratory distress syndrome: comparison using pressure-volume curve or static compliance. Anesthesiology 2007; 106:212-217.
    • (2007) Anesthesiology , vol.106 , pp. 212-217
    • Thille, A.W.1    Richard, J.C.M.2    Maggiore, S.M.3
  • 84
    • 57149101367 scopus 로고    scopus 로고
    • Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury
    • Calfee CS, Ware LB, Eisner MD, et al. Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. Thorax 2008; 63:1083-1089.
    • (2008) Thorax , vol.63 , pp. 1083-1089
    • Calfee, C.S.1    Ware, L.B.2    Eisner, M.D.3
  • 85
    • 60249099585 scopus 로고    scopus 로고
    • Elevated levels of the receptor for advanced glycation end products, a marker of alveolar epithelial type i cell injury, predict impaired alveolar fluid clearance in isolated perfused human lungs
    • Briot R, Frank JA, Uchida T, et al. Elevated levels of the receptor for advanced glycation end products, a marker of alveolar epithelial type I cell injury, predict impaired alveolar fluid clearance in isolated perfused human lungs. Chest 2009; 135:269-275.
    • (2009) Chest , vol.135 , pp. 269-275
    • Briot, R.1    Frank, J.A.2    Uchida, T.3


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