Do glucocorticoids decrease mortality in acute respiratory distress syndrome? A meta-analysis

Respirology

Volumn 12, Issue 4, 2007, Pages 585-590

  Agarwal, Ritesh ^a   Nath, Alok ^a   Aggarwal, Ashutosh N ^a   Gupta, Dheeraj ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; ARDS; Glucocorticoid; Meta analysis; Sepsis

Indexed keywords

FLUDROCORTISONE; GLUCOCORTICOID; HYDROCORTISONE; METHYLPREDNISOLONE;

ADRENAL INSUFFICIENCY; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; DISEASE COURSE; DISEASE EXACERBATION; GENETIC HETEROGENEITY; HUMAN; META ANALYSIS; PRIORITY JOURNAL; SEPTIC SHOCK; STEROID THERAPY; SYSTEMATIC REVIEW; TREATMENT OUTCOME;

HUMANS; RANDOMIZED CONTROLLED TRIALS; RESPIRATORY DISTRESS SYNDROME, ADULT; SURVIVAL ANALYSIS;

EID: 34250763692     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2007.01060.x     Document Type: Article

References (32)

1. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, et al. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am. J. Respir. Crit. Care Med. 1994 149 : 818 24.
2. Ware LB, Matthay MA. The acute respiratory distress syndrome. N. Engl. J. Med. 2000 342 : 1334 49.
3. Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA. Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome. Chest 1987 92 : 1032 6.
4. Luce JM, Montgomery AB, Marks JD, Turner J, Metz CA, et al. Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock. Am. Rev. Respir. Dis. 1988 138 : 62 8.
5. Weigelt JA, Norcross JF, Borman KR, Snyder WH III. Early steroid therapy for respiratory failure. Arch. Surg. 1985 120 : 536 40.
6. Lee HS, Lee JM, Kim MS, Kim HY, Hwangbo B, et al. Low-dose steroid therapy at an early phase of postoperative acute respiratory distress syndrome. Ann. Thorac. Surg. 2005 79 : 405 10.
7. Bernard GR, Luce JM, Sprung CL, Rinaldo JE, Tate RM, et al. High-dose corticosteroids in patients with the adult respiratory distress syndrome. N. Engl. J. Med. 1987 317 : 1565 70.
8. Keel JB, Hauser M, Stocker R, Baumann PC, Speich R. Established acute respiratory distress syndrome: benefit of corticosteroid rescue therapy. Respiration 1998 65 : 258 64.
9. Meduri GU, Tolley EA, Chrousos GP, Stentz F. Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome: evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids. Am. J. Respir. Crit. Care Med. 2002 165 : 983 91.
10. Steinberg KP, Hudson LD, Goodman RB, Hough CL, Lanken PN, et al. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N. Engl. J. Med. 2006 354 : 1671 84.
11. Annane D, Bellissant E, Bollaert PE, Briegel J, Keh D, et al. Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis. BMJ. 2004 329 : 480 8.
12. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control. Clin. Trials 1996 17 : 1 12.
13. Kjaergard LL, Villumsen J, Gluud C. Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses. Ann. Intern. Med. 2001 135 : 982 9.
14. Moher D, Pham B, Jones A, Cook DJ, Jadad AR, et al. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? Lancet 1998 352 : 609 13.
15. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control. Clin. Trials 1986 7 : 177 88.
16. Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann. Intern. Med. 1997 127 : 820 6.
17. Annane D, Sebille V, Bellissant E, Ger-Inf-05 Study Group. Effect of low doses of corticosteroids in septic shock patients with or without early acute respiratory distress syndrome. Crit. Care Med. 2006 34 : 22 30.
18. Meduri GU, Headley AS, Golden E, Carson SJ, Umberger RA, et al. Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial. JAMA 1998 280 : 159 65.
19. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N. Engl. J. Med. 2000 342 : 1301 8.
20. Gerlach H, Keh D, Semmerow A, Busch T, Lewandowski K, et al. Dose-response characteristics during long-term inhalation of nitric oxide in patients with severe acute respiratory distress syndrome: a prospective, randomized, controlled study. Am. J. Respir Crit. Care Med. 2003 167 : 1008 15.
21. Lefering R, Neugebauer EA. Steroid controversy in sepsis and septic shock: a meta-analysis. Crit. Care Med. 1995 23 : 1294 303.
22. Meduri GU, Belenchia JM, Estes RJ, Wunderink RG, el Torky M, et al. Fibroproliferative phase of ARDS. Clinical findings and effects of corticosteroids. Chest 1991 100 : 943 52.
23. Meduri GU, Chinn AJ, Leeper KV, Wunderink RG, Tolley E, et al. Corticosteroid rescue treatment of progressive fibroproliferation in late ARDS. Patterns of response and predictors of outcome. Chest 1994 105 : 1516 27.
24. Meduri GU, Headley S, Tolley E, Shelby M, Stentz F, et al. Plasma and BAL cytokine response to corticosteroid rescue treatment in late ARDS. Chest 1995 108 : 1315 25.
25. Meduri GU, Tolley EA, Chinn A, Stentz F, Postlethwaite A. Procollagen types I and III aminoterminal propeptide levels during acute respiratory distress syndrome and in response to methylprednisolone treatment. Am. J. Respir. Crit. Care Med. 1998 158 : 1432 41.
26. Meduri GU, Muthiah MP, Carratu P, Eltorky M, Chrousos GP. Nuclear factor-kappaB- and glucocorticoid receptor alpha- mediated mechanisms in the regulation of systemic and pulmonary inflammation during sepsis and acute respiratory distress syndrome. Evidence for inflammation-induced target tissue resistance to glucocorticoids. Neuroimmunomodulation 2005 12 : 321 38.
27. Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Intensive Care Med. 2004 30 : 536 55.
28. van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, et al. Intensive insulin therapy in the critically ill patients. N. Engl. J. Med. 2001 345 : 1359 67.
29. Agarwal R, Gupta D. Anticoagulation in sepsis: is low-dose heparin as effective as activated protein C? Intensive Care Med. 2005 31 : 1297 8.
30. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N. Engl. J. Med. 2001 344 : 699 709.
31. Collard HR, Saint S, Matthay MA. Prevention of ventilator-associated pneumonia: an evidence-based systematic review. Ann. Intern. Med. 2003 138 : 494 501.
32. Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N. Engl. J. Med. 2000 342 : 1471 7.