메뉴 건너뛰기




Volumn 11, Issue 1, 2010, Pages 55-66

Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B-1 cells through lineage-specific activity of a unique, intronic promoter

Author keywords

B lymphocyte; B 1 cells; Intronic promoter; Oct1; Oct2; PD L2

Indexed keywords

MEMBRANE PROTEIN; OCTAMER TRANSCRIPTION FACTOR 1; OCTAMER TRANSCRIPTION FACTOR 2; PROGRAMMED DEATH 1 LIGAND 2;

EID: 75049083688     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2009.68     Document Type: Article
Times cited : (15)

References (50)
  • 2
    • 0036888554 scopus 로고    scopus 로고
    • New regulatory co-receptors: Inducible co-stimulator and PD-1
    • Okazaki T, Iwai Y, Honjo T. New regulatory co-receptors: inducible co-stimulator and PD-1. Curr Opin Immunol 2002; 14: 779-782.
    • (2002) Curr Opin Immunol , vol.14 , pp. 779-782
    • Okazaki, T.1    Iwai, Y.2    Honjo, T.3
  • 3
    • 33645863160 scopus 로고    scopus 로고
    • The PD-1PD-L pathway in immunological tolerance
    • Okazaki T, Honjo T. The PD-1PD-L pathway in immunological tolerance. Trends Immunol 2006; 27: 195-201.
    • (2006) Trends Immunol , vol.27 , pp. 195-201
    • Okazaki, T.1    Honjo, T.2
  • 4
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999; 11: 141-151.
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 6
    • 10744220884 scopus 로고    scopus 로고
    • Autoantibodies against cardiac troponin i are responsible for dilated cardiomyopathy in PD-1-deficient mice
    • Okazaki T, Tanaka Y, Nishio R, Mitsuiye T, Mizoguchi A, Wang J et al. Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice. Nat Med 2003; 9: 1477-1483.
    • (2003) Nat Med , vol.9 , pp. 1477-1483
    • Okazaki, T.1    Tanaka, Y.2    Nishio, R.3    Mitsuiye, T.4    Mizoguchi, A.5    Wang, J.6
  • 7
    • 0031685190 scopus 로고    scopus 로고
    • Immunological studies on PD-1 deficient mice: Implication of PD-1 as a negative regulator for B cell responses
    • Nishimura H, Minato N, Nakano T, Honjo T. Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. Int Immunol 1998; 10: 1563-1572.
    • (1998) Int Immunol , vol.10 , pp. 1563-1572
    • Nishimura, H.1    Minato, N.2    Nakano, T.3    Honjo, T.4
  • 8
    • 0037815272 scopus 로고    scopus 로고
    • PD-1 inhibits antiviral immunity at the effector phase in the liver
    • Iwai Y, Terawaki S, Ikegawa M, Okazaki T, Honjo T. PD-1 inhibits antiviral immunity at the effector phase in the liver. J Exp Med 2003; 198: 39-50.
    • (2003) J Exp Med , vol.198 , pp. 39-50
    • Iwai, Y.1    Terawaki, S.2    Ikegawa, M.3    Okazaki, T.4    Honjo, T.5
  • 9
    • 0032736029 scopus 로고    scopus 로고
    • B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and inter-leukin-10 secretion
    • Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and inter-leukin-10 secretion. Nat Med 1999; 5: 1365-1369.
    • (1999) Nat Med , vol.5 , pp. 1365-1369
    • Dong, H.1    Zhu, G.2    Tamada, K.3    Chen, L.4
  • 10
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000; 192: 1027-1034.
    • (2000) J Exp Med , vol.192 , pp. 1027-1034
    • Freeman, G.J.1    Long, A.J.2    Iwai, Y.3    Bourque, K.4    Chernova, T.5    Nishimura, H.6
  • 12
    • 0035794314 scopus 로고    scopus 로고
    • B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
    • Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med 2001; 193: 839-846.
    • (2001) J Exp Med , vol.193 , pp. 839-846
    • Tseng, S.Y.1    Otsuji, M.2    Gorski, K.3    Huang, X.4    Slansky, J.E.5    Pai, S.I.6
  • 14
    • 0037307930 scopus 로고    scopus 로고
    • Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
    • Brown JA, Dorfman DM, Ma FR, Sullivan EL, Munoz O, Wood CR et al. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J Immunol 2003; 170: 1257-1266.
    • (2003) J Immunol , vol.170 , pp. 1257-1266
    • Brown, J.A.1    Dorfman, D.M.2    Ma, F.R.3    Sullivan, E.L.4    Munoz, O.5    Wood, C.R.6
  • 15
    • 32044471903 scopus 로고    scopus 로고
    • Mast cells enhance T cell activation: Importance of mast cell costimulatory molecules and secreted TNF
    • Nakae S, Suto H, Iikura M, Kakurai M, Sedgwick JD, Tsai M et al. Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF. J Immunol 2006; 176: 2238-2248.
    • (2006) J Immunol , vol.176 , pp. 2238-2248
    • Nakae, S.1    Suto, H.2    Iikura, M.3    Kakurai, M.4    Sedgwick, J.D.5    Tsai, M.6
  • 16
    • 34247884612 scopus 로고    scopus 로고
    • The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
    • Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 2007; 8: 239-245.
    • (2007) Nat Immunol , vol.8 , pp. 239-245
    • Sharpe, A.H.1    Wherry, E.J.2    Ahmed, R.3    Freeman, G.J.4
  • 17
    • 33644847590 scopus 로고    scopus 로고
    • Differential role of programmed death-ligand 1 and programmed death-ligand 2 in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis
    • Zhu B, Guleria I, Khosroshahi A, Chitnis T, Imitola J, Azuma M et al. Differential role of programmed death-ligand 1 and programmed death-ligand 2 in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis. J Immunol 2006; 176: 3480-3489.
    • (2006) J Immunol , vol.176 , pp. 3480-3489
    • Zhu, B.1    Guleria, I.2    Khosroshahi, A.3    Chitnis, T.4    Imitola, J.5    Azuma, M.6
  • 18
    • 33846018451 scopus 로고    scopus 로고
    • PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis
    • Carter LL, Leach MW, Azoitei ML, Cui J, Pelker JW, Jussif J et al. PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis. J Neuroimmunol 2007; 182: 124-134.
    • (2007) J Neuroimmunol , vol.182 , pp. 124-134
    • Carter, L.L.1    Leach, M.W.2    Azoitei, M.L.3    Cui, J.4    Pelker, J.W.5    Jussif, J.6
  • 19
    • 21044441208 scopus 로고    scopus 로고
    • Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo
    • Ito T, Ueno T, Clarkson MR, Yuan X, Jurewicz MM, Yagita H et al. Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo. J Immunol 2005; 174: 6648-6656.
    • (2005) J Immunol , vol.174 , pp. 6648-6656
    • Ito, T.1    Ueno, T.2    Clarkson, M.R.3    Yuan, X.4    Jurewicz, M.M.5    Yagita, H.6
  • 20
    • 33750350800 scopus 로고    scopus 로고
    • B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts
    • Hori J, Wang M, Miyashita M, Tanemoto K, Takahashi H, Takemori T et al. B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts. J Immunol 2006; 177: 5928-5935.
    • (2006) J Immunol , vol.177 , pp. 5928-5935
    • Hori, J.1    Wang, M.2    Miyashita, M.3    Tanemoto, K.4    Takahashi, H.5    Takemori, T.6
  • 22
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8: 793-800.
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3    Tamura, H.4    Hirano, F.5    Flies, D.B.6
  • 23
    • 0037867039 scopus 로고    scopus 로고
    • B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism
    • Liu X, Gao JX, Wen J, Yin L, Li O, Zuo T et al. B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism. J Exp Med 2003; 197: 1721-1730.
    • (2003) J Exp Med , vol.197 , pp. 1721-1730
    • Liu, X.1    Gao, J.X.2    Wen, J.3    Yin, L.4    Li, O.5    Zuo, T.6
  • 25
    • 0037442244 scopus 로고    scopus 로고
    • Naturally occurring human IgM antibody that binds B7-DC and potentiates T cell stimulation by dendritic cells
    • Radhakrishnan S, Nguyen LT, Ciric B, Ure DR, Zhou B, Tamada K et al. Naturally occurring human IgM antibody that binds B7-DC and potentiates T cell stimulation by dendritic cells. J Immunol 2003; 170: 1830-1838.
    • (2003) J Immunol , vol.170 , pp. 1830-1838
    • Radhakrishnan, S.1    Nguyen, L.T.2    Ciric, B.3    Ure, D.R.4    Zhou, B.5    Tamada, K.6
  • 27
    • 33845660297 scopus 로고    scopus 로고
    • Induction of a gene expression program in dendritic cells with a cross-linking IgM antibody to the co-stimulatory molecule B7-DC
    • Blocki FA, Radhakrishnan S, Van Keulen VP, Heckman KL, Ciric B, Howe CL et al. Induction of a gene expression program in dendritic cells with a cross-linking IgM antibody to the co-stimulatory molecule B7-DC. FASEB J 2006; 20: 2408-2410.
    • (2006) FASEB J , vol.20 , pp. 2408-2410
    • Blocki, F.A.1    Radhakrishnan, S.2    Van Keulen, V.P.3    Heckman, K.L.4    Ciric, B.5    Howe, C.L.6
  • 28
    • 33846503502 scopus 로고    scopus 로고
    • B7-DC/PD-L2 cross-linking induces NF-kappaB-depen-dent protection of dendritic cells from cell death
    • Radhakrishnan S, Nguyen LT, Ciric B, Van Keulen VP, Pease LR. B7-DC/PD-L2 cross-linking induces NF-kappaB-depen-dent protection of dendritic cells from cell death. J Immunol 2007; 178: 1426-1432.
    • (2007) J Immunol , vol.178 , pp. 1426-1432
    • Radhakrishnan, S.1    Nguyen, L.T.2    Ciric, B.3    Van Keulen, V.P.4    Pease, L.R.5
  • 29
    • 33748881940 scopus 로고    scopus 로고
    • Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation
    • Kuipers H, Muskens F, Willart M, Hijdra D, van Assema FB, Coyle AJ et al. Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation. Eur J Immunol 2006; 36: 2472-2482.
    • (2006) Eur J Immunol , vol.36 , pp. 2472-2482
    • Kuipers, H.1    Muskens, F.2    Willart, M.3    Hijdra, D.4    Van Assema, F.B.5    Coyle, A.J.6
  • 30
    • 34247382104 scopus 로고    scopus 로고
    • Ligands for programmed cell death 1 gene in patients with systemic lupus erythematosus
    • Wang SC, Lin CH, Ou TT, Wu CC, Tsai WC, Hu CJ et al. Ligands for programmed cell death 1 gene in patients with systemic lupus erythematosus. J Rheumatol 2007; 34: 721-725.
    • (2007) J Rheumatol , vol.34 , pp. 721-725
    • Wang, S.C.1    Lin, C.H.2    Ou, T.T.3    Wu, C.C.4    Tsai, W.C.5    Hu, C.J.6
  • 31
    • 34548810934 scopus 로고    scopus 로고
    • PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V(H)11/V(H)
    • Zhong X, Tumang JR, Gao W, Bai C, Rothstein TL. PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V(H)11/V(H)12 and phosphatidylcholine binding. Eur J Immunol 2007; 37: 2405-2410.
    • (2007) Eur J Immunol , vol.37 , pp. 2405-2410
    • Zhong, X.1    Tumang, J.R.2    Gao, W.3    Bai, C.4    Rothstein, T.L.5
  • 32
    • 0037111483 scopus 로고    scopus 로고
    • Expression of programmed death 1 ligands by murine T cells and APC
    • Yamazaki T, Akiba H, Iwai H, Matsuda H, Aoki M, Tanno Y et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 2002; 169: 5538-5545.
    • (2002) J Immunol , vol.169 , pp. 5538-5545
    • Yamazaki, T.1    Akiba, H.2    Iwai, H.3    Matsuda, H.4    Aoki, M.5    Tanno, Y.6
  • 34
    • 0019972628 scopus 로고
    • Anti-phosphor-ylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae
    • Briles DE, Forman C, Hudak S, Claflin JL. Anti-phosphor-ylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae. J Exp Med 1982; 156: 1177-1185.
    • (1982) J Exp Med , vol.156 , pp. 1177-1185
    • Briles, D.E.1    Forman, C.2    Hudak, S.3    Claflin, J.L.4
  • 35
    • 0032445137 scopus 로고    scopus 로고
    • A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection
    • Boes M, Prodeus AP, Schmidt T, Carroll MC, Chen J. A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection. J Exp Med 1998; 188: 2381-2386.
    • (1998) J Exp Med , vol.188 , pp. 2381-2386
    • Boes, M.1    Prodeus, A.P.2    Schmidt, T.3    Carroll, M.C.4    Chen, J.5
  • 36
    • 0032787091 scopus 로고    scopus 로고
    • Control of early viral and bacterial distribution and disease by natural antibodies
    • Ochsenbein AF, Fehr T, Lutz C, Suter M, Brombacher F, Hengartner H et al. Control of early viral and bacterial distribution and disease by natural antibodies. Science 1999; 286: 2156-2159.
    • (1999) Science , vol.286 , pp. 2156-2159
    • Ochsenbein, A.F.1    Fehr, T.2    Lutz, C.3    Suter, M.4    Brombacher, F.5    Hengartner, H.6
  • 37
    • 0034679710 scopus 로고    scopus 로고
    • B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection
    • Baumgarth N, Herman OC, Jager GC, Brown LE, Herzenberg LA, Chen J. B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection. J Exp Med 2000; 192: 271-280.
    • (2000) J Exp Med , vol.192 , pp. 271-280
    • Baumgarth, N.1    Herman, O.C.2    Jager, G.C.3    Brown, L.E.4    Herzenberg, L.A.5    Chen, J.6
  • 38
    • 22544470027 scopus 로고    scopus 로고
    • B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae
    • Haas KM, Poe JC, Steeber DA, Tedder TF. B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae. Immunity 2005; 23: 7-18.
    • (2005) Immunity , vol.23 , pp. 7-18
    • Haas, K.M.1    Poe, J.C.2    Steeber, D.A.3    Tedder, T.F.4
  • 40
    • 73249130668 scopus 로고    scopus 로고
    • A novel subpopulation of B1 B cells is enriched with autoreactivity in normal and lupus-prone mice
    • in press
    • Zhong X, Lau S, Bai C, Degauque N, Holodick NE, Steven SJ et al. A novel subpopulation of B1 B cells is enriched with autoreactivity in normal and lupus-prone mice. Arthr Rheum 2009; (in press).
    • (2009) Arthr Rheum
    • Zhong, X.1    Lau, S.2    Bai, C.3    Degauque, N.4    Holodick, N.E.5    Steven, S.J.6
  • 41
    • 0346056794 scopus 로고    scopus 로고
    • Cloning, genomic organization, expression, and effect on beta-casein promoter activity of a novel isoform of the mouse Oct-1 transcription factor
    • Zhao FQ, Zheng Y, Dong B, Oka T. Cloning, genomic organization, expression, and effect on beta-casein promoter activity of a novel isoform of the mouse Oct-1 transcription factor. Gene 2004; 326: 175-187.
    • (2004) Gene , vol.326 , pp. 175-187
    • Zhao, F.Q.1    Zheng, Y.2    Dong, B.3    Oka, T.4
  • 42
    • 0034177158 scopus 로고    scopus 로고
    • Phosphorylation of Oct-2 at sites located in the POU domain induces differential downregulation of Oct-2 DNA-binding ability
    • Pevzner V, Kraft R, Kostka S, Lipp M. Phosphorylation of Oct-2 at sites located in the POU domain induces differential downregulation of Oct-2 DNA-binding ability. Biochem J 2000; 347: 29-35.
    • (2000) Biochem J , vol.347 , pp. 29-35
    • Pevzner, V.1    Kraft, R.2    Kostka, S.3    Lipp, M.4
  • 43
    • 0025238851 scopus 로고
    • Octamer transcription factors and the cell type-specificity of immunoglobulin gene expression
    • Kemler I, Schaffner W. Octamer transcription factors and the cell type-specificity of immunoglobulin gene expression. FASEB J 1990; 4: 1444-1449.
    • (1990) FASEB J , vol.4 , pp. 1444-1449
    • Kemler, I.1    Schaffner, W.2
  • 44
    • 17444429245 scopus 로고    scopus 로고
    • Cutting edge: Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors
    • Tumang JR, Frances R, Yeo SG, Rothstein TL. Cutting edge: spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors. J Immunol 2005; 174: 3173-3177.
    • (2005) J Immunol , vol.174 , pp. 3173-3177
    • Tumang, J.R.1    Frances, R.2    Yeo, S.G.3    Rothstein, T.L.4
  • 45
    • 0028920079 scopus 로고
    • Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells
    • Rothstein TL, Wang JK, Panka DJ, Foote LC, Wang Z, Stanger B et al. Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. Nature 1995; 374: 163-165.
    • (1995) Nature , vol.374 , pp. 163-165
    • Rothstein, T.L.1    Wang, J.K.2    Panka, D.J.3    Foote, L.C.4    Wang, Z.5    Stanger, B.6
  • 46
    • 37249085691 scopus 로고    scopus 로고
    • Cloning of full genome sequence of hepatitis e virus of Shanghai swine isolate using RACE method
    • Shen Q, Zhang W, Cao X, Mou J, Cui L, Hua X. Cloning of full genome sequence of hepatitis E virus of Shanghai swine isolate using RACE method. Virol J 2007; 4: 98.
    • (2007) Virol J , vol.4 , pp. 98
    • Shen, Q.1    Zhang, W.2    Cao, X.3    Mou, J.4    Cui, L.5    Hua, X.6
  • 47
    • 67649963598 scopus 로고    scopus 로고
    • LBP-1a binds a subset of immunoglobulin switch regions in vivo and represses class switch recombination
    • Repetny KJ, Zhong X, Holodick NE, Rothstein TL, Hansen U. LBP-1a binds a subset of immunoglobulin switch regions in vivo and represses class switch recombination. Eur J Immunol 2009; 39: 1387-1394.
    • (2009) Eur J Immunol , vol.39 , pp. 1387-1394
    • Repetny, K.J.1    Zhong, X.2    Holodick, N.E.3    Rothstein, T.L.4    Hansen, U.5
  • 48
    • 21244462272 scopus 로고    scopus 로고
    • Cutting edge: B-1 cells are deficient in Lck: Defective B cell receptor signal transduc-tion in B-1 cells occurs in the absence of elevated Lck expression
    • Frances R, Tumang JR, Rothstein TL. Cutting edge: B-1 cells are deficient in Lck: defective B cell receptor signal transduc-tion in B-1 cells occurs in the absence of elevated Lck expression. J Immunol 2005; 175: 27-31.
    • (2005) J Immunol , vol.175 , pp. 27-31
    • Frances, R.1    Tumang, J.R.2    Rothstein, T.L.3
  • 49
    • 0037443519 scopus 로고    scopus 로고
    • Cutting edge: CD40 engagement eliminates the need for Bruton's tyrosine kinase in B cell receptor signaling for NF-kappa B
    • Mizuno T, Rothstein TL. Cutting edge: CD40 engagement eliminates the need for Bruton's tyrosine kinase in B cell receptor signaling for NF-kappa B. J Immunol 2003; 170: 2806-2810.
    • (2003) J Immunol , vol.170 , pp. 2806-2810
    • Mizuno, T.1    Rothstein, T.L.2
  • 50
    • 4444384574 scopus 로고    scopus 로고
    • Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics
    • Tumang JR, Hastings WD, Bai C, Rothstein TL. Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics. Eur J Immunol 2004; 34: 2158-2167.
    • (2004) Eur J Immunol , vol.34 , pp. 2158-2167
    • Tumang, J.R.1    Hastings, W.D.2    Bai, C.3    Rothstein, T.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.