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Volumn 137, Issue 1, 2010, Pages 177-184

Targeting primary afferent nerves for novel antitussive therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUSSIVE AGENT; LIDOCAINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; VANILLOID RECEPTOR 1; VOLTAGE GATED SODIUM CHANNEL;

EID: 74949133882     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.09-1960     Document Type: Article
Times cited : (37)

References (59)
  • 1
    • 33144457858 scopus 로고    scopus 로고
    • American College of Chest Physicians (ACCP). Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines
    • Irwin RS, Baumann MH, Bolser DC, et al; American College of Chest Physicians (ACCP). Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006; 129(1 suppl): 1S-23S.
    • (2006) Chest , vol.129 , Issue.1 SUPPL.
    • Irwin, R.S.1    Baumann, M.H.2    Bolser, D.C.3
  • 2
    • 77950132500 scopus 로고    scopus 로고
    • Over-the-counter medications for acute cough in children and adults in ambulatory settings
    • CD001831
    • Smith SM, Schroeder K, Fahey T. Over-the-counter medications for acute cough in children and adults in ambulatory settings. Cochrane Database Syst Rev. 2008;(1): CD001831.
    • (2008) Cochrane Database Syst Rev , Issue.1
    • Smith, S.M.1    Schroeder, K.2    Fahey, T.3
  • 3
    • 56249147031 scopus 로고    scopus 로고
    • Over-the-counter cough medicines in children: Neither safe or efficacious?
    • Smith SM, Henman M, Schroeder K, Fahey T. Over-the-counter cough medicines in children: neither safe or efficacious? Br J Gen Pract. 2008; 58(556): 757-758.
    • (2008) Br J Gen Pract , vol.58 , Issue.556 , pp. 757-758
    • Smith, S.M.1    Henman, M.2    Schroeder, K.3    Fahey, T.4
  • 4
    • 56049112789 scopus 로고    scopus 로고
    • Central mechanisms IV: Conscious control of cough and the placebo effect
    • Eccles R. Central mechanisms IV: conscious control of cough and the placebo effect. Handb Exp Pharmacol. 2009; 187: 241-262.
    • (2009) Handb Exp Pharmacol , vol.187 , pp. 241-262
    • Eccles, R.1
  • 5
    • 0037405333 scopus 로고    scopus 로고
    • Effect of acute unilateral middle cerebral artery infarcts on voluntary cough and the laryngeal cough reflex
    • Stephens RE, Addington WR, Widdicombe JG. Effect of acute unilateral middle cerebral artery infarcts on voluntary cough and the laryngeal cough reflex. Am J Phys Med Rehabil. 2003; 82(5): 379-383.
    • (2003) Am J Phys Med Rehabil , vol.82 , Issue.5 , pp. 379-383
    • Stephens, R.E.1    Addington, W.R.2    Widdicombe, J.G.3
  • 6
    • 77049183726 scopus 로고
    • Respiratory reflexes from the trachea and bronchi of the cat
    • Widdicombe JG. Respiratory reflexes from the trachea and bronchi of the cat. J Physiol. 1954; 123(1): 55-70.
    • (1954) J Physiol , vol.123 , Issue.1 , pp. 55-70
    • Widdicombe, J.G.1
  • 7
    • 3042684373 scopus 로고    scopus 로고
    • Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guineapigs
    • Canning BJ, Mazzone SB, Meeker SN, Mori N, Reynolds SM, Undem BJ. Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guineapigs. J Physiol. 2004; 557(pt 2): 543-558.
    • (2004) J Physiol , vol.557 , Issue.PART 2 , pp. 543-558
    • Canning, B.J.1    Mazzone, S.B.2    Meeker, S.N.3    Mori, N.4    Reynolds, S.M.5    Undem, B.J.6
  • 10
    • 0034899135 scopus 로고    scopus 로고
    • Sensitivity of vagal afferent endings to chemical irritants in the rat lung
    • Ho CY, Gu Q, Lin YS, Lee LY. Sensitivity of vagal afferent endings to chemical irritants in the rat lung. Respir Physiol. 2001; 127(2-3): 113-124.
    • (2001) Respir Physiol , vol.127 , Issue.2-3 , pp. 113-124
    • Ho, C.Y.1    Gu, Q.2    Lin, Y.S.3    Lee, L.Y.4
  • 11
    • 0036302137 scopus 로고    scopus 로고
    • Interactions between vagal afferent nerve subtypes mediating cough
    • Canning BJ. Interactions between vagal afferent nerve subtypes mediating cough. Pulm Pharmacol Ther. 2002; 15(3): 187-192.
    • (2002) Pulm Pharmacol Ther , vol.15 , Issue.3 , pp. 187-192
    • Canning, B.J.1
  • 12
    • 29244463541 scopus 로고    scopus 로고
    • Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs
    • Mazzone SB, Mori N, Canning BJ. Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs. J Physiol. 2005; 569(Pt 2): 559-573.
    • (2005) J Physiol , vol.569 , Issue.PART 2 , pp. 559-573
    • Mazzone, S.B.1    Mori, N.2    Canning, B.J.3
  • 13
    • 68049085625 scopus 로고    scopus 로고
    • Convergence of nasal and tracheal neural pathways in modulating the cough response in guinea pigs
    • Plevkova J, Antosiewicz J, Varechova S, et al. Convergence of nasal and tracheal neural pathways in modulating the cough response in guinea pigs. J Physiol Pharmacol. 2009; 60(2): 89-93.
    • (2009) J Physiol Pharmacol , vol.60 , Issue.2 , pp. 89-93
    • Plevkova, J.1    Antosiewicz, J.2    Varechova, S.3
  • 14
    • 61649128432 scopus 로고    scopus 로고
    • Cough and gastroesophageal reflux: Insights from animal models
    • Kollarik M, Brozmanova M. Cough and gastroesophageal reflux: insights from animal models. Pulm Pharmacol Ther. 2009; 22(2): 130-134.
    • (2009) Pulm Pharmacol Ther , vol.22 , Issue.2 , pp. 130-134
    • Kollarik, M.1    Brozmanova, M.2
  • 15
    • 57049123897 scopus 로고    scopus 로고
    • P2X2 receptors differentiate placodal vs. neural crest C-fiber phenotypes innervating guinea pig lungs and esophagus
    • Kwong K, Kollarik M, Nassenstein C, Ru F, Undem BJ. P2X2 receptors differentiate placodal vs. neural crest C-fiber phenotypes innervating guinea pig lungs and esophagus. Am J Physiol Lung Cell Mol Physiol. 2008; 295(5): L858-L865.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295 , Issue.5
    • Kwong, K.1    Kollarik, M.2    Nassenstein, C.3    Ru, F.4    Undem, B.J.5
  • 16
    • 56049117435 scopus 로고    scopus 로고
    • Canning BJ, Chou YL. Cough sensors. I. Physiological and pharmacological properties of the afferent nerves regulating cough. Handb Exp Pharmacol. 2009; 187: 23-47.
    • Canning BJ, Chou YL. Cough sensors. I. Physiological and pharmacological properties of the afferent nerves regulating cough. Handb Exp Pharmacol. 2009; 187: 23-47.
  • 17
    • 0023786292 scopus 로고
    • Lung C-fibre receptor activation and defensive reflexes in anaesthetized cats
    • Tatar M, Webber SE, Widdicombe JG. Lung C-fibre receptor activation and defensive reflexes in anaesthetized cats. J Physiol. 1988; 402(1): 411-420.
    • (1988) J Physiol , vol.402 , Issue.1 , pp. 411-420
    • Tatar, M.1    Webber, S.E.2    Widdicombe, J.G.3
  • 18
    • 0032926445 scopus 로고    scopus 로고
    • Characterization of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea
    • Kajekar R, Proud D, Myers AC, Meeker SN, Undem BJ. Characterization of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea. J Pharmacol Exp Ther. 1999; 289(2): 682-687.
    • (1999) J Pharmacol Exp Ther , vol.289 , Issue.2 , pp. 682-687
    • Kajekar, R.1    Proud, D.2    Myers, A.C.3    Meeker, S.N.4    Undem, B.J.5
  • 19
    • 0030821651 scopus 로고    scopus 로고
    • Activation of large conductance potassium channels inhibits the afferent and efferent function of airway sensory nerves in the guinea pig
    • Fox AJ, Barnes PJ, Venkatesan P, Belvisi MG. Activation of large conductance potassium channels inhibits the afferent and efferent function of airway sensory nerves in the guinea pig. J Clin Invest. 1997; 99(3): 513-519.
    • (1997) J Clin Invest , vol.99 , Issue.3 , pp. 513-519
    • Fox, A.J.1    Barnes, P.J.2    Venkatesan, P.3    Belvisi, M.G.4
  • 20
    • 32144462268 scopus 로고    scopus 로고
    • Effect of nociceptin in acid-evoked cough and airway sensory nerve activation in guinea pigs
    • Lee MG, Undem BJ, Brown C, Carr MJ. Effect of nociceptin in acid-evoked cough and airway sensory nerve activation in guinea pigs. Am J Respir Crit Care Med. 2006; 173(3): 271-275.
    • (2006) Am J Respir Crit Care Med , vol.173 , Issue.3 , pp. 271-275
    • Lee, M.G.1    Undem, B.J.2    Brown, C.3    Carr, M.J.4
  • 21
    • 0021344458 scopus 로고
    • Capsaicin inhalation in man and the effects of sodium cromoglycate
    • Collier JG, Fuller RW. Capsaicin inhalation in man and the effects of sodium cromoglycate. Br J Pharmacol. 1984; 81(1): 113-117.
    • (1984) Br J Pharmacol , vol.81 , Issue.1 , pp. 113-117
    • Collier, J.G.1    Fuller, R.W.2
  • 22
    • 58149107126 scopus 로고    scopus 로고
    • Clinical development of TRPV1 antagonists: Targeting a pivotal point in the pain pathway
    • Gunthorpe MJ, Chizh BA. Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway. Drug Discov Today. 2009; 14(1-2): 56-67.
    • (2009) Drug Discov Today , vol.14 , Issue.1-2 , pp. 56-67
    • Gunthorpe, M.J.1    Chizh, B.A.2
  • 23
    • 34548825160 scopus 로고    scopus 로고
    • Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade
    • Gavva NR, Bannon AW, Hovland DN Jr, et al. Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade. J Pharmacol Exp Ther. 2007; 323(1): 128-137.
    • (2007) J Pharmacol Exp Ther , vol.323 , Issue.1 , pp. 128-137
    • Gavva, N.R.1    Bannon, A.W.2    Hovland Jr, D.N.3
  • 24
    • 41749117999 scopus 로고    scopus 로고
    • Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans
    • Gavva NR, Treanor JJ, Garami A, et al. Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans. Pain. 2008; 136(1-2): 202-210.
    • (2008) Pain , vol.136 , Issue.1-2 , pp. 202-210
    • Gavva, N.R.1    Treanor, J.J.2    Garami, A.3
  • 25
    • 45749092572 scopus 로고    scopus 로고
    • 1H-inden-4-yl)-3-(2-(piperidin-1-yl)- 4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats
    • 1H-inden-4-yl)-3-(2-(piperidin-1-yl)- 4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats. J Pharmacol Exp Ther. 2008; 326(1): 218-229.
    • (2008) J Pharmacol Exp Ther , vol.326 , Issue.1 , pp. 218-229
    • Lehto, S.G.1    Tamir, R.2    Deng, H.3
  • 26
    • 1842475312 scopus 로고    scopus 로고
    • Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
    • Bandell M, Story GM, Hwang SW, et al. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron. 2004; 41(6): 849-857.
    • (2004) Neuron , vol.41 , Issue.6 , pp. 849-857
    • Bandell, M.1    Story, G.M.2    Hwang, S.W.3
  • 27
    • 1642430679 scopus 로고    scopus 로고
    • Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
    • Jordt SE, Bautista DM, Chuang HH, et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature. 2004; 427(6971): 260-265.
    • (2004) Nature , vol.427 , Issue.6971 , pp. 260-265
    • Jordt, S.E.1    Bautista, D.M.2    Chuang, H.H.3
  • 29
    • 63849217721 scopus 로고    scopus 로고
    • Transient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation
    • Taylor-Clark TE, Kiros F, Carr MJ, McAlexander MA. Transient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation. Am J Respir Cell Mol Biol. 2009; 40(6): 756-762.
    • (2009) Am J Respir Cell Mol Biol , vol.40 , Issue.6 , pp. 756-762
    • Taylor-Clark, T.E.1    Kiros, F.2    Carr, M.J.3    McAlexander, M.A.4
  • 30
    • 0004758614 scopus 로고
    • Effect of possible smog irritants on human subjects
    • Sim VM, Pattle RE. Effect of possible smog irritants on human subjects. J Am Med Assoc. 1957; 165(15): 1908-1913.
    • (1957) J Am Med Assoc , vol.165 , Issue.15 , pp. 1908-1913
    • Sim, V.M.1    Pattle, R.E.2
  • 31
    • 0026550871 scopus 로고
    • Acute effects of acrolein on breathing: Role of vagal bronchopulmonary afferents
    • Lee BP, Morton RF, Lee LY. Acute effects of acrolein on breathing: role of vagal bronchopulmonary afferents. J Appl Physiol. 1992; 72(3): 1050-1056.
    • (1992) J Appl Physiol , vol.72 , Issue.3 , pp. 1050-1056
    • Lee, B.P.1    Morton, R.F.2    Lee, L.Y.3
  • 32
    • 2942532888 scopus 로고    scopus 로고
    • Lack of role for the vanilloid receptor in response to several inspired irritant air pollutants in the C57Bl/6J mouse
    • Symanowicz PT, Gianutsos G, Morris JB. Lack of role for the vanilloid receptor in response to several inspired irritant air pollutants in the C57Bl/6J mouse. Neurosci Lett. 2004; 362(2): 150-153.
    • (2004) Neurosci Lett , vol.362 , Issue.2 , pp. 150-153
    • Symanowicz, P.T.1    Gianutsos, G.2    Morris, J.B.3
  • 33
    • 70449534119 scopus 로고    scopus 로고
    • TRPA1 agonists evoke coughing in guinea-pig and human volunteers
    • Birrell MA, Belvisi MG, Grace M, et al. TRPA1 agonists evoke coughing in guinea-pig and human volunteers. Am J Respir Crit Care Med. 2009; 180(11): 1040-1047.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.11 , pp. 1040-1047
    • Birrell, M.A.1    Belvisi, M.G.2    Grace, M.3
  • 34
    • 33846692923 scopus 로고    scopus 로고
    • Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
    • Macpherson LJ, Dubin AE, Evans MJ, et al. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature. 2007; 445(7127): 541-545.
    • (2007) Nature , vol.445 , Issue.7127 , pp. 541-545
    • Macpherson, L.J.1    Dubin, A.E.2    Evans, M.J.3
  • 35
    • 33845900989 scopus 로고    scopus 로고
    • TRP channel activation by reversible covalent modification
    • Hinman A, Chuang HH, Bautista DM, Julius D. TRP channel activation by reversible covalent modification. Proc Natl Acad Sci USA. 2006; 103(51): 19564-19568.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.51 , pp. 19564-19568
    • Hinman, A.1    Chuang, H.H.2    Bautista, D.M.3    Julius, D.4
  • 36
    • 48949120476 scopus 로고    scopus 로고
    • Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal
    • Taylor-Clark TE, McAlexander MA, Nassenstein C, et al. Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal. J Physiol. 2008; 586(14): 3447-3459.
    • (2008) J Physiol , vol.586 , Issue.14 , pp. 3447-3459
    • Taylor-Clark, T.E.1    McAlexander, M.A.2    Nassenstein, C.3
  • 37
    • 38549092780 scopus 로고    scopus 로고
    • Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1(TRPA1)
    • Taylor-Clark TE, Undem BJ, Macglashan DW, Jr, Ghatta S, Carr MJ, McAlexander MA. Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1(TRPA1). Mol Pharmacol. 2008; 73(2): 274-281.
    • (2008) Mol Pharmacol , vol.73 , Issue.2 , pp. 274-281
    • Taylor-Clark, T.E.1    Undem, B.J.2    Macglashan Jr, D.W.3    Ghatta, S.4    Carr, M.J.5    McAlexander, M.A.6
  • 38
    • 63849101712 scopus 로고    scopus 로고
    • Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1
    • Taylor-Clark TE, Ghatta S, Bettner W, Undem BJ. Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1. Mol Pharmacol. 2009; 75(4): 820-829.
    • (2009) Mol Pharmacol , vol.75 , Issue.4 , pp. 820-829
    • Taylor-Clark, T.E.1    Ghatta, S.2    Bettner, W.3    Undem, B.J.4
  • 39
    • 56449110894 scopus 로고    scopus 로고
    • HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity
    • Eid SR, Crown ED, Moore EL, et al. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Mol Pain. 2008; 4: 48.
    • (2008) Mol Pain , vol.4 , pp. 48
    • Eid, S.R.1    Crown, E.D.2    Moore, E.L.3
  • 40
    • 38949175353 scopus 로고    scopus 로고
    • A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
    • Petrus M, Peier AM, Bandell M, et al. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain. 2007; 3: 40.
    • (2007) Mol Pain , vol.3 , pp. 40
    • Petrus, M.1    Peier, A.M.2    Bandell, M.3
  • 41
    • 34347400078 scopus 로고    scopus 로고
    • Intravenous lidocaine: An outdated or under-utilized treatment for pain?
    • McCleane G. Intravenous lidocaine: an outdated or under-utilized treatment for pain? J Palliat Med. 2007; 10(3): 798-805.
    • (2007) J Palliat Med , vol.10 , Issue.3 , pp. 798-805
    • McCleane, G.1
  • 42
    • 40049090069 scopus 로고    scopus 로고
    • Voltage-gated sodium channels in nociceptive versus non-nociceptive nodose vagal sensory neurons innervating guinea pig lungs
    • Kwong K, Carr MJ, Gibbard A, et al. Voltage-gated sodium channels in nociceptive versus non-nociceptive nodose vagal sensory neurons innervating guinea pig lungs. J Physiol. 2008; 586(5): 1321-1336.
    • (2008) J Physiol , vol.586 , Issue.5 , pp. 1321-1336
    • Kwong, K.1    Carr, M.J.2    Gibbard, A.3
  • 43
    • 8544273283 scopus 로고    scopus 로고
    • Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia
    • Raymond CK, Castle J, Garrett-Engele P, et al. Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia. J Biol Chem. 2004; 279(44): 46234-46241.
    • (2004) J Biol Chem , vol.279 , Issue.44 , pp. 46234-46241
    • Raymond, C.K.1    Castle, J.2    Garrett-Engele, P.3
  • 44
    • 34548419652 scopus 로고    scopus 로고
    • A stop codon mutation in SCN9A causes lack of pain sensation
    • Ahmad S, Dahllund L, Eriksson AB, et al. A stop codon mutation in SCN9A causes lack of pain sensation. Hum Mol Genet. 2007; 16(17): 2114-2121.
    • (2007) Hum Mol Genet , vol.16 , Issue.17 , pp. 2114-2121
    • Ahmad, S.1    Dahllund, L.2    Eriksson, A.B.3
  • 45
    • 33845901486 scopus 로고    scopus 로고
    • An SCN9A channelopathy causes congenital inability to experience pain
    • Cox JJ, Reimann F, Nicholas AK, et al. An SCN9A channelopathy causes congenital inability to experience pain. Nature. 2006; 444(7121): 894-898.
    • (2006) Nature , vol.444 , Issue.7121 , pp. 894-898
    • Cox, J.J.1    Reimann, F.2    Nicholas, A.K.3
  • 46
    • 0032400799 scopus 로고    scopus 로고
    • Slow closed-state inactivation: A novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel
    • Cummins TR, Howe JR, Waxman SG. Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel. J Neurosci. 1998; 18(23): 9607-9619.
    • (1998) J Neurosci , vol.18 , Issue.23 , pp. 9607-9619
    • Cummins, T.R.1    Howe, J.R.2    Waxman, S.G.3
  • 47
    • 0033363999 scopus 로고    scopus 로고
    • The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
    • Akopian AN, Souslova V, England S, et al. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat Neurosci. 1999; 2(6): 541-548.
    • (1999) Nat Neurosci , vol.2 , Issue.6 , pp. 541-548
    • Akopian, A.N.1    Souslova, V.2    England, S.3
  • 48
    • 0034900781 scopus 로고    scopus 로고
    • Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons
    • Renganathan M, Cummins TR, Waxman SG. Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons. J Neurophysiol. 2001; 86(2): 629-640.
    • (2001) J Neurophysiol , vol.86 , Issue.2 , pp. 629-640
    • Renganathan, M.1    Cummins, T.R.2    Waxman, S.G.3
  • 49
    • 0032535602 scopus 로고    scopus 로고
    • Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro
    • Gold MS, Levine JD, Correa AM. Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro. J Neurosci. 1998; 18(24): 10345-10355.
    • (1998) J Neurosci , vol.18 , Issue.24 , pp. 10345-10355
    • Gold, M.S.1    Levine, J.D.2    Correa, A.M.3
  • 50
    • 17844397209 scopus 로고    scopus 로고
    • Prostaglandin E2 potentiates a TTX-resistant sodium current in rat capsaicin-sensitive vagal pulmonary sensory neurones
    • Kwong K, Lee LY. Prostaglandin E2 potentiates a TTX-resistant sodium current in rat capsaicin-sensitive vagal pulmonary sensory neurones. J Physiol. 2005; 564(Pt 2): 437-450.
    • (2005) J Physiol , vol.564 , Issue.PART 2 , pp. 437-450
    • Kwong, K.1    Lee, L.Y.2
  • 51
    • 34347213786 scopus 로고    scopus 로고
    • A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat
    • Jarvis MF, Honore P, Shieh CC, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci USA. 2007; 104(20): 8520-8525.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.20 , pp. 8520-8525
    • Jarvis, M.F.1    Honore, P.2    Shieh, C.C.3
  • 52
    • 0034843601 scopus 로고    scopus 로고
    • Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons
    • Herzog RI, Cummins TR, Waxman SG. Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. J Neurophysiol. 2001; 86(3): 1351-1364.
    • (2001) J Neurophysiol , vol.86 , Issue.3 , pp. 1351-1364
    • Herzog, R.I.1    Cummins, T.R.2    Waxman, S.G.3
  • 53
    • 0033572137 scopus 로고    scopus 로고
    • A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons
    • Cummins TR, Dib-Hajj SD, Black JA, Akopian AN, Wood JN, Waxman SG. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. J Neurosci. 1999; 19(24): RC43.
    • (1999) J Neurosci , vol.19 , Issue.24
    • Cummins, T.R.1    Dib-Hajj, S.D.2    Black, J.A.3    Akopian, A.N.4    Wood, J.N.5    Waxman, S.G.6
  • 54
    • 0034554778 scopus 로고    scopus 로고
    • Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons
    • Cummins TR, Black JA, Dib-Hajj SD, Waxman SG. Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons. J Neurosci. 2000; 20(23): 8754-8761.
    • (2000) J Neurosci , vol.20 , Issue.23 , pp. 8754-8761
    • Cummins, T.R.1    Black, J.A.2    Dib-Hajj, S.D.3    Waxman, S.G.4
  • 55
    • 4544381958 scopus 로고    scopus 로고
    • PGE2 increases the tetrodotoxin-resistant Nav1.9 sodium current in mouse DRG neurons via G-proteins
    • Rush AM, Waxman SG. PGE2 increases the tetrodotoxin-resistant Nav1.9 sodium current in mouse DRG neurons via G-proteins. Brain Res. 2004; 1023(2): 264-271.
    • (2004) Brain Res , vol.1023 , Issue.2 , pp. 264-271
    • Rush, A.M.1    Waxman, S.G.2
  • 56
    • 40849083674 scopus 로고    scopus 로고
    • Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism
    • Maingret F, Coste B, Padilla F, et al. Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism. J Gen Physiol. 2008; 131(3): 211-225.
    • (2008) J Gen Physiol , vol.131 , Issue.3 , pp. 211-225
    • Maingret, F.1    Coste, B.2    Padilla, F.3
  • 57
    • 33845631301 scopus 로고    scopus 로고
    • The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity
    • Amaya F, Wang H, Costigan M, et al. The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. J Neurosci. 2006; 26(50): 12852-12860.
    • (2006) J Neurosci , vol.26 , Issue.50 , pp. 12852-12860
    • Amaya, F.1    Wang, H.2    Costigan, M.3
  • 58
    • 21544455502 scopus 로고    scopus 로고
    • Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior
    • Priest BT, Murphy BA, Lindia JA, et al. Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior. Proc Natl Acad Sci USA. 2005; 102(26): 9382-9387.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.26 , pp. 9382-9387
    • Priest, B.T.1    Murphy, B.A.2    Lindia, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.