-
1
-
-
2642584339
-
Transcription factor decoy for AP-1 reduces mesangial cell proliferation and extracellular matrix production in vitro and in vivo
-
Ahn JD, Morishita R, Kaneda Y Kim HJ, Kim YD, Lee HJ, Lee KU, Park JY, Kim YH, Park KK, Chang YC, Yoon KH, Kwon HS, Park KG, Lee IK (2004) Transcription factor decoy for AP-1 reduces mesangial cell proliferation and extracellular matrix production in vitro and in vivo. Gene Therapy 11: 916-923.
-
(2004)
Gene Therapy
, vol.11
, pp. 916-923
-
-
Ahn, J.D.1
Morishita, R.2
Kaneda, Y.3
Kim, H.J.4
Kim, Y.D.5
Lee, H.J.6
Lee, K.U.7
Park, J.Y.8
Kim, Y.H.9
Park, K.K.10
Chang, Y.C.11
Yoon, K.H.12
Kwon, H.S.13
Park, K.G.14
Lee, I.K.15
-
2
-
-
0035882440
-
Regulation of mesangial cell function by vasodilatory signaling molecules
-
Buschhausen L, Seibold S, Gross O, Matthaeus T, Weber M, Schulze-Lohoff E (2001) Regulation of mesangial cell function by vasodilatory signaling molecules. Cardiovasc Res 51 : 463-469.
-
(2001)
Cardiovasc Res
, vol.51
, pp. 463-469
-
-
Buschhausen, L.1
Seibold, S.2
Gross, O.3
Matthaeus, T.4
Weber, M.5
Schulze-Lohoff, E.6
-
3
-
-
33645218707
-
Determination of AKFPD in whole blood of rat by HPLC-UV
-
Cao W, He L, Liu W, Huang Z, Cheng Z. (2006) Determination of AKFPD in whole blood of rat by HPLC-UV. J Chromatogr B Analyt Technol Biomed Life Sci. 833: 257-259.
-
(2006)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.833
, pp. 257-259
-
-
Cao, W.1
He, L.2
Liu, W.3
Huang, Z.4
Cheng, Z.5
-
4
-
-
0033672331
-
Glycosaminoglycan therapy prevents TGF-ß1 overexpression and pathologic changes in renal tissue of long-term diabetic rats
-
Ceol M, Gambaro G, Sauer U, Baggio B, Anglani F, Forino M, Facchin S, Bordin L, Weigert C, Nerlich A, Schleicher ED (2000) Glycosaminoglycan therapy prevents TGF-ß1 overexpression and pathologic changes in renal tissue of long-term diabetic rats. J Am Soc Nephrol 11: 2324-2336.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 2324-2336
-
-
Ceol, M.1
Gambaro, G.2
Sauer, U.3
Baggio, B.4
Anglani, F.5
Forino, M.6
Facchin, S.7
Bordin, L.8
Weigert, C.9
Nerlich, A.10
Schleicher, E.D.11
-
5
-
-
0036707875
-
PPAR agonists amplify iNOS expression while inhibiting NF-B: Implications for mesangial cell activation by cytokines
-
Cernuda-Morollón E, Rodríguez-Pascual F, Klatt P, Lamas S, Pérez-Sala D (2002) PPAR agonists amplify iNOS expression while inhibiting NF-B: implications for mesangial cell activation by cytokines. J Am Soc Nephrol 13 : 2223-2231.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2223-2231
-
-
Cernuda-Morollón, E.1
Rodríguez-Pascual, F.2
Klatt, P.3
Lamas, S.4
Pérez-Sala, D.5
-
6
-
-
0000432767
-
Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages
-
Chin BY, Petrache I, Choi AM, Choi AE. (1999) Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages. J Biol Chem 274: 11362-11368.
-
(1999)
J Biol Chem
, vol.274
, pp. 11362-11368
-
-
Chin, B.Y.1
Petrache, I.2
Choi, A.M.3
Choi, A.E.4
-
7
-
-
34548834734
-
Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis
-
Cho ME, Smith DC, Branton MH, Penzak SR, Kopp JB (2007) Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis. Clin J Am Soc Nephrol 2: 906-913.
-
(2007)
Clin J Am Soc Nephrol
, vol.2
, pp. 906-913
-
-
Cho, M.E.1
Smith, D.C.2
Branton, M.H.3
Penzak, S.R.4
Kopp, J.B.5
-
8
-
-
28944450314
-
Mitogen-activated protein kinase (MAPK)
-
Cuschieri J, Maier RV (2005) Mitogen-activated protein kinase (MAPK). Crit Care Med 33: S417-S419.
-
(2005)
Crit Care Med
, vol.33
-
-
Cuschieri, J.1
Maier, R.V.2
-
9
-
-
21644453426
-
The anti-fibrotic effect of pirfenidone in rat liver fibrosis is mediated by downregulation of procollagen alpha1(I), TIMP-1 and MMP-2
-
Di Sario A, Bendia E, Macarri G Candelaresi C, Taffetani S, Marzioni M, Omenetti A, De Minicis S, Trozzi L, Benedetti A. (2004) The anti-fibrotic effect of pirfenidone in rat liver fibrosis is mediated by downregulation of procollagen alpha1(I), TIMP-1 and MMP-2. Dig Liver Dis 36: 744-751.
-
(2004)
Dig Liver Dis
, vol.36
, pp. 744-751
-
-
Di Sario, A.1
Bendia, E.2
Macarri, G.3
Candelaresi, C.4
Taffetani, S.5
Marzioni, M.6
Omenetti, A.7
De Minicis, S.8
Trozzi, L.9
Benedetti, A.10
-
11
-
-
0035718790
-
Pirfenidone reduces in vitro rat renal fibroblast activation and mitogenesis
-
Hewitson TD, Kelynack KJ, Tait MG Martic M, Jones CL, Margolin SB, Becker GJ (2001) Pirfenidone reduces in vitro rat renal fibroblast activation and mitogenesis. J Nephrol 14: 453-460.
-
(2001)
J Nephrol
, vol.14
, pp. 453-460
-
-
Hewitson, T.D.1
Kelynack, K.J.2
Tait, M.G.3
Martic, M.4
Jones, C.L.5
Margolin, S.B.6
Becker, G.J.7
-
12
-
-
0037216749
-
Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets
-
Hommes DW, Peppelenbosch MP, van Deventer SJ (2003) Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets. Gut 52: 144-51.
-
(2003)
Gut
, vol.52
, pp. 144-151
-
-
Hommes, D.W.1
Peppelenbosch, M.P.2
van Deventer, S.J.3
-
13
-
-
48749112311
-
Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor-beta-induced mouse fibrosis
-
Ikawa Y, Ng PS, Endo K, Kondo M, Chujo S, Ishida W, Shirasaki F, Fujimoto M, Takehara K (2008) Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor-beta-induced mouse fibrosis. J Cell Physiol 216: 680-687.
-
(2008)
J Cell Physiol
, vol.216
, pp. 680-687
-
-
Ikawa, Y.1
Ng, P.S.2
Endo, K.3
Kondo, M.4
Chujo, S.5
Ishida, W.6
Shirasaki, F.7
Fujimoto, M.8
Takehara, K.9
-
15
-
-
0029953788
-
Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease
-
Kopp JB, Factor VM, Mozes M Nagy P, Sanderson N, Böttinger EP, Klotman PE, Thorgeirsson SS (1996) Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease. Lab Invest 74: 991-1003.
-
(1996)
Lab Invest
, vol.74
, pp. 991-1003
-
-
Kopp, J.B.1
Factor, V.M.2
Mozes, M.3
Nagy, P.4
Sanderson, N.5
Böttinger, E.P.6
Klotman, P.E.7
Thorgeirsson, S.S.8
-
16
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J (2001) Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81: 807-869.
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
17
-
-
33644638349
-
Renal fibrosis: New insights into the pathogenesis and therapeutics
-
Liu Y (2006) Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int 69: 213-217.
-
(2006)
Kidney Int
, vol.69
, pp. 213-217
-
-
Liu, Y.1
-
18
-
-
0034946204
-
Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats
-
Miric G, Dallemagne C, Endre Z, Margolin S, Taylor SM, Brown L. (2001) Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats. Br J Pharmacol 133: 687-694.
-
(2001)
Br J Pharmacol
, vol.133
, pp. 687-694
-
-
Miric, G.1
Dallemagne, C.2
Endre, Z.3
Margolin, S.4
Taylor, S.M.5
Brown, L.6
-
19
-
-
1942518942
-
Interaction of AP-1 and the ctgf gene: A possible driver of chondrocyte hypertrophy in growth cartilage
-
Moritani NH, Kubota S, Eguchi T Fukunaga T, Yamashiro T, Takano-Yamamoto T, Tahara H, Ohyama K, Sugahara T, Takigawa M (2003) Interaction of AP-1 and the ctgf gene: a possible driver of chondrocyte hypertrophy in growth cartilage. J Bone Miner Metab 21: 205-210.
-
(2003)
J Bone Miner Metab
, vol.21
, pp. 205-210
-
-
Moritani, N.H.1
Kubota, S.2
Eguchi, T.3
Fukunaga, T.4
Yamashiro, T.5
Takano-Yamamoto, T.6
Tahara, H.7
Ohyama, K.8
Sugahara, T.9
Takigawa, M.10
-
20
-
-
37548998589
-
Pirfenidone inhibits the expression of HSP47 in TGF-beta1-stimulated human lung fibroblasts
-
Nakayama S, Mukae H, Sakamoto N Kakugawa T, Yoshioka S, Soda H, Oku H, Urata Y, Kondo T, Kubota H, Nagata K, Kohno S (2008) Pirfenidone inhibits the expression of HSP47 in TGF-beta1-stimulated human lung fibroblasts. Life Sci 82: 210-217.
-
(2008)
Life Sci
, vol.82
, pp. 210-217
-
-
Nakayama, S.1
Mukae, H.2
Sakamoto, N.3
Kakugawa, T.4
Yoshioka, S.5
Soda, H.6
Oku, H.7
Urata, Y.8
Kondo, T.9
Kubota, H.10
Nagata, K.11
Kohno, S.12
-
21
-
-
0035991411
-
Interactions of human mesangial cells with IgA and IgA-containing immune complexes
-
Novak J, Vu HL, Novak L Julian BA, Mestecky J, Tomana M. (2002) Interactions of human mesangial cells with IgA and IgA-containing immune complexes. Kidney Int 62: 465-475.
-
(2002)
Kidney Int
, vol.62
, pp. 465-475
-
-
Novak, J.1
Vu, H.L.2
Novak, L.3
Julian, B.A.4
Mestecky, J.5
Tomana, M.6
-
22
-
-
21044454845
-
Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
-
Okada H, Kikuta T, Kobayashi T Inoue T, Kanno Y, Takigawa M, Sugaya T, Kopp JB, Suzuki H (2005) Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. J Am Soc Nephrol 16: 133-143.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 133-143
-
-
Okada, H.1
Kikuta, T.2
Kobayashi, T.3
Inoue, T.4
Kanno, Y.5
Takigawa, M.6
Sugaya, T.7
Kopp, J.B.8
Suzuki, H.9
-
23
-
-
42049109923
-
Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer
-
Ouyang X, Jessen WJ, Al-Ahmadie H, Serio AM, Lin Y, Shih WJ, Reuter VE, Scardino PT, Shen MM, Aronow BJ, Vickers AJ, Gerald WL, Abate-Shen C (2008) Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer. Cancer Res. 68: 2132-2144.
-
(2008)
Cancer Res
, vol.68
, pp. 2132-2144
-
-
Ouyang, X.1
Jessen, W.J.2
Al-Ahmadie, H.3
Serio, A.M.4
Lin, Y.5
Shih, W.J.6
Reuter, V.E.7
Scardino, P.T.8
Shen, M.M.9
Aronow, B.J.10
Vickers, A.J.11
Gerald, W.L.12
Abate-Shen, C.13
-
25
-
-
15044359781
-
Integrated actions of transforming growth factor-1 and connective tissue growth factor in renal fibrosis
-
Qi W, Twigg S, Chen X, Polhill TS, Poronnik P, Gilbert RE, Pollock CA (2005) Integrated actions of transforming growth factor-1 and connective tissue growth factor in renal fibrosis. Am J Physiol Renal Physiol 288: F800-F809.
-
(2005)
Am J Physiol Renal Physiol
, vol.288
-
-
Qi, W.1
Twigg, S.2
Chen, X.3
Polhill, T.S.4
Poronnik, P.5
Gilbert, R.E.6
Pollock, C.A.7
-
26
-
-
0034761986
-
Pathogenesis of diabetic nephropathy: Focus on transforming growth factor-beta and connective tissue growth factor
-
Sakharova OV, Taal MW, Brenner BM (2001) Pathogenesis of diabetic nephropathy: focus on transforming growth factor-beta and connective tissue growth factor. Curr Opin Nephrol Hypertens 10: 727-738.
-
(2001)
Curr Opin Nephrol Hypertens
, vol.10
, pp. 727-738
-
-
Sakharova, O.V.1
Taal, M.W.2
Brenner, B.M.3
-
28
-
-
18244362560
-
Increased expression of cystic fibrosis transmembrane conductance regulator in rat liver after common bile duct ligation
-
Shen H, Fan Y, Yang X, Burczynski FJ, Li P, Gong Y (2005) Increased expression of cystic fibrosis transmembrane conductance regulator in rat liver after common bile duct ligation. J Cell Physiol 203: 599-603.
-
(2005)
J Cell Physiol
, vol.203
, pp. 599-603
-
-
Shen, H.1
Fan, Y.2
Yang, X.3
Burczynski, F.J.4
Li, P.5
Gong, Y.6
-
29
-
-
39049187839
-
-
Tao LJ, Zhang J, Hu GY. (2004) Effects of 1-(3-fluorophenyl)-5-methyl-2- (1H)-pyridone on renal fibroblast in rats: Zhong Nan Da Xue Xue Bao Yi Xue Ban., Apr 29 (2): 139-141.
-
Tao LJ, Zhang J, Hu GY. (2004) Effects of 1-(3-fluorophenyl)-5-methyl-2- (1H)-pyridone on renal fibroblast in rats: Zhong Nan Da Xue Xue Bao Yi Xue Ban., Apr 29 (2): 139-141.
-
-
-
-
30
-
-
33748078489
-
Long-term administration of pirfenidone improves cardiac function in mdx mice
-
Van Erp C, Irwin NG, Hoey AJ (2006) Long-term administration of pirfenidone improves cardiac function in mdx mice. Muscle Nerve 34: 327-334.
-
(2006)
Muscle Nerve
, vol.34
, pp. 327-334
-
-
Van Erp, C.1
Irwin, N.G.2
Hoey, A.J.3
-
31
-
-
0033760187
-
AP-1 proteins mediate hyperglycemia-induced activation of the human TGF-ß1 promoter in mesangial cells
-
Weigert C, Sauer U, Bodbeck K Pfeiffer A, Häring HU, Schleicher ED (2000) AP-1 proteins mediate hyperglycemia-induced activation of the human TGF-ß1 promoter in mesangial cells. J Am Soc Nephrol 11: 2007-2016.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 2007-2016
-
-
Weigert, C.1
Sauer, U.2
Bodbeck, K.3
Pfeiffer, A.4
Häring, H.U.5
Schleicher, E.D.6
-
32
-
-
33845262861
-
Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway
-
Wolf G (2006) Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway. Kidney Int 70: 1914-1919.
-
(2006)
Kidney Int
, vol.70
, pp. 1914-1919
-
-
Wolf, G.1
-
33
-
-
0037177841
-
Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta
-
Xiao YQ, Malcolm K, Worthen GS, Gardai S, Schiemann WP, Fadok VA, Bratton DL, Henson PM (2002) Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta. J Biol Chem 277: 14884-14893.
-
(2002)
J Biol Chem
, vol.277
, pp. 14884-14893
-
-
Xiao, Y.Q.1
Malcolm, K.2
Worthen, G.S.3
Gardai, S.4
Schiemann, W.P.5
Fadok, V.A.6
Bratton, D.L.7
Henson, P.M.8
-
34
-
-
1842708905
-
Effect of transforming growth factor-beta on activity of connective tissue growth factor gene promoter in mouse NIH/3T3 fibroblasts
-
Zhao Q, Chen N, Wang WM, Lu J, Dai BB (2004) Effect of transforming growth factor-beta on activity of connective tissue growth factor gene promoter in mouse NIH/3T3 fibroblasts. Acta Pharmacol Sin 25: 485-489.
-
(2004)
Acta Pharmacol Sin
, vol.25
, pp. 485-489
-
-
Zhao, Q.1
Chen, N.2
Wang, W.M.3
Lu, J.4
Dai, B.B.5
|