메뉴 건너뛰기




Volumn 54, Issue 2, 2010, Pages 193-198

Interactions between antiepileptic and chemotherapeutic drugs in children with brain tumors: Is it time to change treatment?

Author keywords

Antiepileptic drugs; Brain tumors; Chemotherapy; Interaction; Seizures

Indexed keywords

ANTICONVULSIVE AGENT; ANTINEOPLASTIC AGENT; BUSULFAN; CARBAMAZEPINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DEXAMETHASONE; DOCETAXEL; ETIRACETAM; ETOPOSIDE; FELBAMATE; GLYCOPROTEIN P INHIBITOR; IRINOTECAN; LAMOTRIGINE; METHOTREXATE; OXCARBAZEPINE; PACLITAXEL; PHENOBARBITAL; PHENYTOIN; PLACEBO; PROCARBAZINE; TAMOXIFEN; TENIPOSIDE; TOPIRAMATE; TOPOTECAN; UNINDEXED DRUG; VALSPODAR; VERAPAMIL; VINCRISTINE;

EID: 74849115324     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.22276     Document Type: Review
Times cited : (41)

References (60)
  • 1
    • 1242296884 scopus 로고    scopus 로고
    • Seizures as the presenting symptom of brain tumours in children
    • Ibrahim K, Appleton R. Seizures as the presenting symptom of brain tumours in children. Seizure 2004;13:108-112.
    • (2004) Seizure , vol.13 , pp. 108-112
    • Ibrahim, K.1    Appleton, R.2
  • 2
    • 0036245549 scopus 로고    scopus 로고
    • Medical management of patients with brain tumors
    • Wen PY, Marks PW. Medical management of patients with brain tumors. Curr Opin Oncol 2002;14:299-307.
    • (2002) Curr Opin Oncol , vol.14 , pp. 299-307
    • Wen, P.Y.1    Marks, P.W.2
  • 3
    • 0034705172 scopus 로고    scopus 로고
    • Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors
    • Glantz MJ, Cole BF, Forsyth PA, et al. Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors. Neurology 2000;54:1886-1893.
    • (2000) Neurology , vol.54 , pp. 1886-1893
    • Glantz, M.J.1    Cole, B.F.2    Forsyth, P.A.3
  • 4
    • 1042278085 scopus 로고    scopus 로고
    • Treating seizures in patients with brain tumors: Drug interactions between antiepileptic and chemotherapeutic agents
    • Vecht CJ, Wagner GL, Wilms EB. Treating seizures in patients with brain tumors: Drug interactions between antiepileptic and chemotherapeutic agents. Semin Oncol 2003;30:49-52.
    • (2003) Semin Oncol , vol.30 , pp. 49-52
    • Vecht, C.J.1    Wagner, G.L.2    Wilms, E.B.3
  • 5
    • 0038726223 scopus 로고    scopus 로고
    • Interactions between antiepileptic and chemotherapeutic drugs
    • Vecht CJ, Wagner GL, Wilms EB. Interactions between antiepileptic and chemotherapeutic drugs. Lancet Neurol 2003;2:404-409.
    • (2003) Lancet Neurol , vol.2 , pp. 404-409
    • Vecht, C.J.1    Wagner, G.L.2    Wilms, E.B.3
  • 6
    • 33947191055 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
    • Vredenburgh JJ, Desjardins A, Herndon JE II, et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res 2007;13:1253-1259.
    • (2007) Clin Cancer Res , vol.13 , pp. 1253-1259
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon II, J.E.3
  • 7
    • 0031801368 scopus 로고    scopus 로고
    • Phase I study of paclitaxel in patients with recurrent malignant glioma: A North American Brain Tumor Consortium report
    • Chang SM, Kuhn JG, Rizzo J, et al. Phase I study of paclitaxel in patients with recurrent malignant glioma: A North American Brain Tumor Consortium report. J Clin Oncol 1998;16:2188-2194.
    • (1998) J Clin Oncol , vol.16 , pp. 2188-2194
    • Chang, S.M.1    Kuhn, J.G.2    Rizzo, J.3
  • 8
    • 0033398416 scopus 로고    scopus 로고
    • Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors
    • Villikka K, Kivisto KT, Maenpaa H, et al. Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors. Clin Pharmacol Ther 1999;66:589-593.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 589-593
    • Villikka, K.1    Kivisto, K.T.2    Maenpaa, H.3
  • 9
    • 0021035301 scopus 로고
    • Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide
    • Santos GW, Tutschka PJ, Brookmeyer R, et al. Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. N Engl J Med 1983;309:1347-1353.
    • (1983) N Engl J Med , vol.309 , pp. 1347-1353
    • Santos, G.W.1    Tutschka, P.J.2    Brookmeyer, R.3
  • 10
    • 0034702552 scopus 로고    scopus 로고
    • Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia
    • Relling MV, Pui CH, Sandlund JT, et al. Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia. Lancet 2000;356:285-290.
    • (2000) Lancet , vol.356 , pp. 285-290
    • Relling, M.V.1    Pui, C.H.2    Sandlund, J.T.3
  • 11
    • 31544474851 scopus 로고    scopus 로고
    • Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
    • Prados MD, Lamborn KR, Chang S, et al. Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neuro Oncol 2006;8: 67-78.
    • (2006) Neuro Oncol , vol.8 , pp. 67-78
    • Prados, M.D.1    Lamborn, K.R.2    Chang, S.3
  • 12
    • 34548009373 scopus 로고    scopus 로고
    • Significant drug interaction: Phenytoin toxicity due to erlotinib
    • Grenader T, Gipps M, Shavit L, et al. Significant drug interaction: Phenytoin toxicity due to erlotinib. Lung Cancer 2007;57:404-406.
    • (2007) Lung Cancer , vol.57 , pp. 404-406
    • Grenader, T.1    Gipps, M.2    Shavit, L.3
  • 13
    • 0142060067 scopus 로고    scopus 로고
    • The role of chemotherapy in brain metastasis
    • Van der Bent MJ. The role of chemotherapy in brain metastasis. Eur J Cancer 2003;39:2114-2120.
    • (2003) Eur J Cancer , vol.39 , pp. 2114-2120
    • Van der Bent, M.J.1
  • 14
    • 0021285163 scopus 로고
    • Phenytoin impairs the bioavailability of dexamethasone in neurological and neurosurgical patients
    • Chalk JB, Ridgeway K, Brophy T, et al. Phenytoin impairs the bioavailability of dexamethasone in neurological and neurosurgical patients. J Neurol Neurosurg Psychiatry 1984;47:1087-1090.
    • (1984) J Neurol Neurosurg Psychiatry , vol.47 , pp. 1087-1090
    • Chalk, J.B.1    Ridgeway, K.2    Brophy, T.3
  • 15
    • 0021341426 scopus 로고
    • Disposition of total and unbound prednisolone in renal transplant patients receiving anticonvulsants
    • Gambertoglio JG, Holford NH, Kapusnik JE, et al. Disposition of total and unbound prednisolone in renal transplant patients receiving anticonvulsants. Kidney Int 1984;25:119-123.
    • (1984) Kidney Int , vol.25 , pp. 119-123
    • Gambertoglio, J.G.1    Holford, N.H.2    Kapusnik, J.E.3
  • 16
    • 0017200001 scopus 로고
    • Effects of enzyme induction on metabolism of prednisolone. Clinical and laboratory study
    • Brooks PM, Buchanan WW, Grove M, et al. Effects of enzyme induction on metabolism of prednisolone. Clinical and laboratory study. Ann Rheum Dis 1976;35:339-343.
    • (1976) Ann Rheum Dis , vol.35 , pp. 339-343
    • Brooks, P.M.1    Buchanan, W.W.2    Grove, M.3
  • 17
    • 33646861168 scopus 로고    scopus 로고
    • Retrospective analysis of the efficacy and tolerability of levetiracetam in brain tumor patients
    • Newton HB, Goldlust SA, Pearl D. Retrospective analysis of the efficacy and tolerability of levetiracetam in brain tumor patients. J Neurooncol 2006;78:99-102.
    • (2006) J Neurooncol , vol.78 , pp. 99-102
    • Newton, H.B.1    Goldlust, S.A.2    Pearl, D.3
  • 18
    • 0345530892 scopus 로고    scopus 로고
    • Levetiracetam: Preliminary experience in patients with primary brain tumours
    • Wagner GL, Wilms EB, Van Donselaar CA, et al. Levetiracetam: Preliminary experience in patients with primary brain tumours. Seizure 2003;12:585-586.
    • (2003) Seizure , vol.12 , pp. 585-586
    • Wagner, G.L.1    Wilms, E.B.2    Van Donselaar, C.A.3
  • 19
    • 0029977212 scopus 로고    scopus 로고
    • Add-on gabapentin for refractory seizures in patients with brain tumours
    • Perry JRSC. Add-on gabapentin for refractory seizures in patients with brain tumours. Can J Neurol Sci 1996;23:128-131.
    • (1996) Can J Neurol Sci , vol.23 , pp. 128-131
    • Perry, J.R.S.C.1
  • 20
    • 13444282312 scopus 로고    scopus 로고
    • Retrospective study of the use of levetiracetam in childhood seizure disorders
    • Koukkari MW, Guarino EJ. Retrospective study of the use of levetiracetam in childhood seizure disorders. J Child Neuro1 2004; 19:944-947.
    • (2004) J Child Neuro1 , vol.19 , pp. 944-947
    • Koukkari, M.W.1    Guarino, E.J.2
  • 21
    • 0037387689 scopus 로고    scopus 로고
    • Levetiracetam for benign epilepsy of childhood with centrotemporal spikes: Three cases
    • Bello-Espinosa LE, Roberts SL. Levetiracetam for benign epilepsy of childhood with centrotemporal spikes: Three cases. Seizure 2003;12:157-159.
    • (2003) Seizure , vol.12 , pp. 157-159
    • Bello-Espinosa, L.E.1    Roberts, S.L.2
  • 22
    • 0242606907 scopus 로고    scopus 로고
    • Landau-Kleffner syndrome responsive to levetiracetam
    • Kossoff EH, Boatman D, Freeman JM. Landau-Kleffner syndrome responsive to levetiracetam. Epilepsy Behav 2003;4:571-575.
    • (2003) Epilepsy Behav , vol.4 , pp. 571-575
    • Kossoff, E.H.1    Boatman, D.2    Freeman, J.M.3
  • 23
    • 12144253720 scopus 로고    scopus 로고
    • Clinical experience with levetiracetam in childhood epilepsy: An add-on and mono-therapy trial
    • Lagae L, Buyse G, Ceulemans B. Clinical experience with levetiracetam in childhood epilepsy: An add-on and mono-therapy trial. Seizure 2005;14:66-71.
    • (2005) Seizure , vol.14 , pp. 66-71
    • Lagae, L.1    Buyse, G.2    Ceulemans, B.3
  • 24
    • 0032861821 scopus 로고    scopus 로고
    • Monotherapy trials with gabapentin for partial epilepsy
    • Beydoun A. Monotherapy trials with gabapentin for partial epilepsy. Epilepsia 1999;40:S13-S16.
    • (1999) Epilepsia , vol.40
    • Beydoun, A.1
  • 25
    • 59449088484 scopus 로고    scopus 로고
    • Levetiracetam for seizures in children with brain tumors and other cancers
    • Partap S, Fisher PG. Levetiracetam for seizures in children with brain tumors and other cancers. Pediatr Blood Cancer 2009;52: 288-289.
    • (2009) Pediatr Blood Cancer , vol.52 , pp. 288-289
    • Partap, S.1    Fisher, P.G.2
  • 26
    • 0033811604 scopus 로고    scopus 로고
    • Brain plasticity and cellular mechanisms of epileptogenesis in human and experimental cortical dysplasia
    • Babb TL, Ying Z, Mikuni N, et al. Brain plasticity and cellular mechanisms of epileptogenesis in human and experimental cortical dysplasia. Epilepsia 2000;41:S76-S81.
    • (2000) Epilepsia , vol.41
    • Babb, T.L.1    Ying, Z.2    Mikuni, N.3
  • 27
    • 0032880718 scopus 로고    scopus 로고
    • Mechanisms underlying epileptogenesis in cortical malformations
    • Jacobs KM, Kharazia VN, Prince DA. Mechanisms underlying epileptogenesis in cortical malformations. Epilepsy Res 1999;36: 165-188.
    • (1999) Epilepsy Res , vol.36 , pp. 165-188
    • Jacobs, K.M.1    Kharazia, V.N.2    Prince, D.A.3
  • 28
    • 0030476396 scopus 로고    scopus 로고
    • Epilepsy in patients with central nervous system tumors
    • Villemure JG, de Tribolet N. Epilepsy in patients with central nervous system tumors. Curr Opin Neurol 1996;9:424-428.
    • (1996) Curr Opin Neurol , vol.9 , pp. 424-428
    • Villemure, J.G.1    de Tribolet, N.2
  • 29
    • 4344590532 scopus 로고    scopus 로고
    • Magnetoencephalography (MEG) predicts focal epileptogenicity in cavernomas
    • Stefan H, Scheler G, Hummel C, et al. Magnetoencephalography (MEG) predicts focal epileptogenicity in cavernomas. J Neurol Neurosurg Psychiatry 2004;75:1309-1313.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 1309-1313
    • Stefan, H.1    Scheler, G.2    Hummel, C.3
  • 30
    • 0034911570 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor protein expression in glioneuronal tumours from patients with intractable epilepsy
    • Aronica E, Yankaya B, Jansen GH, et al. Ionotropic and metabotropic glutamate receptor protein expression in glioneuronal tumours from patients with intractable epilepsy. Neuropathol Appl Neurobiol 2001;27:223-237.
    • (2001) Neuropathol Appl Neurobiol , vol.27 , pp. 223-237
    • Aronica, E.1    Yankaya, B.2    Jansen, G.H.3
  • 31
    • 0037069271 scopus 로고    scopus 로고
    • Epilepsy after brain insult: Targeting epileptogenesis
    • Herman ST. Epilepsy after brain insult: Targeting epileptogenesis. Neurology 2002;59:S21-S26.
    • (2002) Neurology , vol.59
    • Herman, S.T.1
  • 32
    • 0025613141 scopus 로고
    • Epilepsy and brain tumours
    • Cascino GD. Epilepsy and brain tumours. Epilepsia 1990;37:S37-S44.
    • (1990) Epilepsia , vol.37
    • Cascino, G.D.1
  • 33
    • 0030005209 scopus 로고    scopus 로고
    • Perilesional neurochemical changes in focal epilepsies
    • Wolf HK, Roos D, Blumcke I, et al. Perilesional neurochemical changes in focal epilepsies. Acta Neuropathol (Berl) 1996;91:376-384.
    • (1996) Acta Neuropathol (Berl) , vol.91 , pp. 376-384
    • Wolf, H.K.1    Roos, D.2    Blumcke, I.3
  • 34
    • 9644279570 scopus 로고    scopus 로고
    • Seizure prophylaxis in patients with brain tumors: A meta-analysis
    • Sirven JI, Wingerchuk DM, Drazkowski JF, et al. Seizure prophylaxis in patients with brain tumors: A meta-analysis. Mayo Clin Proc 2004;79:1489-1494.
    • (2004) Mayo Clin Proc , vol.79 , pp. 1489-1494
    • Sirven, J.I.1    Wingerchuk, D.M.2    Drazkowski, J.F.3
  • 35
    • 0025210536 scopus 로고
    • Influence of surgery and antiepileptic drugs on seizures symptomatic of cerebral tumours
    • Franceschetti S, Binelli S, Casazza M, et al. Influence of surgery and antiepileptic drugs on seizures symptomatic of cerebral tumours. Acta Neurochir (Wien) 1990;103:47-51.
    • (1990) Acta Neurochir (Wien) , vol.103 , pp. 47-51
    • Franceschetti, S.1    Binelli, S.2    Casazza, M.3
  • 36
    • 0025617527 scopus 로고
    • Post-operative epilepsy and the efficacy of anticonvulsant therapy
    • Shaw MD. Post-operative epilepsy and the efficacy of anticonvulsant therapy. Acta Neurochir Suppl (Wien) 1990;50:55-57.
    • (1990) Acta Neurochir Suppl (Wien) , vol.50 , pp. 55-57
    • Shaw, M.D.1
  • 37
    • 0020535425 scopus 로고
    • Phenytoin and postoperative epilepsy. A double-blind study
    • North JB, Penhall RK, Hanieh A, et al. Phenytoin and postoperative epilepsy. A double-blind study. J Neurosurg 1983;58:672-677.
    • (1983) J Neurosurg , vol.58 , pp. 672-677
    • North, J.B.1    Penhall, R.K.2    Hanieh, A.3
  • 38
    • 0035900333 scopus 로고    scopus 로고
    • P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
    • Potschka H, Fedrowitz M, Loscher W. P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain. Neuroreport 2001;12:3557-3560.
    • (2001) Neuroreport , vol.12 , pp. 3557-3560
    • Potschka, H.1    Fedrowitz, M.2    Loscher, W.3
  • 39
    • 0037101618 scopus 로고    scopus 로고
    • Limbic seizures induce Pglycoprotein in rodent brain: Functional implications for pharmacoresistance
    • Rizzi M, Caccia S, Guiso G, et al. Limbic seizures induce Pglycoprotein in rodent brain: Functional implications for pharmacoresistance. J Neurosci 2002;22:5833-5839.
    • (2002) J Neurosci , vol.22 , pp. 5833-5839
    • Rizzi, M.1    Caccia, S.2    Guiso, G.3
  • 40
    • 0035828178 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein is involved in the regulation of extracellular levels of phenytoin in the brain
    • Potschka H, LoscherW. Multidrug resistance-associated protein is involved in the regulation of extracellular levels of phenytoin in the brain. Neuroreport 2001;12:2387-2389.
    • (2001) Neuroreport , vol.12 , pp. 2387-2389
    • Potschka, H.1    LoscherW2
  • 41
    • 0037178642 scopus 로고    scopus 로고
    • P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: Evidence from microdialysis experiments in rats
    • Potschka H, Fedrowitz M, Loscher W. P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: Evidence from microdialysis experiments in rats. Neurosci Lett 2002;327:173-176.
    • (2002) Neurosci Lett , vol.327 , pp. 173-176
    • Potschka, H.1    Fedrowitz, M.2    Loscher, W.3
  • 42
    • 0037399407 scopus 로고    scopus 로고
    • Mechanisms of antiepileptic drug resistance
    • Sisodiya SM. Mechanisms of antiepileptic drug resistance. Curr Opin Neurol 2003;16:197-201.
    • (2003) Curr Opin Neurol , vol.16 , pp. 197-201
    • Sisodiya, S.M.1
  • 43
    • 0036361559 scopus 로고    scopus 로고
    • OC144-093, a novel P glycoprotein inhibitor for the enhancement of antiepileptic therapy
    • Newman MJ, Dixon R, Toyonaga B. OC144-093, a novel P glycoprotein inhibitor for the enhancement of antiepileptic therapy. Novartis Found Symp 2002;243:213-226.
    • (2002) Novartis Found Symp , vol.243 , pp. 213-226
    • Newman, M.J.1    Dixon, R.2    Toyonaga, B.3
  • 44
    • 3242765938 scopus 로고    scopus 로고
    • Pharmacoresistance and expression of multidrug transporter P-glycoprotein in kindled rats
    • Potschka H, Volk HA, Loscher W. Pharmacoresistance and expression of multidrug transporter P-glycoprotein in kindled rats. Neuroreport 2004;15:1657-1661.
    • (2004) Neuroreport , vol.15 , pp. 1657-1661
    • Potschka, H.1    Volk, H.A.2    Loscher, W.3
  • 45
    • 0029582977 scopus 로고
    • The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: Implications for drug interactions
    • Kivisto KT, Kroemer HK, Eichelbaum M. The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: Implications for drug interactions. Br J Clin Pharmacol 1995; 40:523-530.
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 523-530
    • Kivisto, K.T.1    Kroemer, H.K.2    Eichelbaum, M.3
  • 46
    • 30844451771 scopus 로고    scopus 로고
    • Update on pharmacogenetics in epilepsy: A brief review
    • Szoeke CE, Newton M, Wood JM, et al. Update on pharmacogenetics in epilepsy: A brief review. Lancet Neurol 2006;5:189-196.
    • (2006) Lancet Neurol , vol.5 , pp. 189-196
    • Szoeke, C.E.1    Newton, M.2    Wood, J.M.3
  • 47
    • 0035107070 scopus 로고    scopus 로고
    • Nitrosourea-cisplatin-based chemotherapy associated with valproate: Increase of haematologic toxicity
    • BourgV, Lebrun C, Chichmanian RM, et al. Nitrosourea-cisplatin-based chemotherapy associated with valproate: Increase of haematologic toxicity. Ann Oncol 2001;12:217-219.
    • (2001) Ann Oncol , vol.12 , pp. 217-219
    • Bourg, V.1    Lebrun, C.2    Chichmanian, R.M.3
  • 48
    • 20944451523 scopus 로고    scopus 로고
    • P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated with standard chemotherapy
    • Oberndorfer S, Piribauer M, Marosi C, et al. P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated with standard chemotherapy. J Neurooncol 2005;72:255-260.
    • (2005) J Neurooncol , vol.72 , pp. 255-260
    • Oberndorfer, S.1    Piribauer, M.2    Marosi, C.3
  • 49
    • 11144356543 scopus 로고    scopus 로고
    • French JA, Kanner AM, Bautista J, et al. Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology, Quality Standards Subcommittee of the American Academy of Neurology, American Epilepsy Society. Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004;62:1252-1260.
    • French JA, Kanner AM, Bautista J, et al. Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology, Quality Standards Subcommittee of the American Academy of Neurology, American Epilepsy Society. Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004;62:1252-1260.
  • 50
    • 0036220551 scopus 로고    scopus 로고
    • The importance of drug interactions in epilepsy therapy
    • Patsalos PN, Fröscher W, Pisani F, et al. The importance of drug interactions in epilepsy therapy. Epilepsia 2002;43:365-385.
    • (2002) Epilepsia , vol.43 , pp. 365-385
    • Patsalos, P.N.1    Fröscher, W.2    Pisani, F.3
  • 51
    • 1642442730 scopus 로고    scopus 로고
    • Efficacy and tolerability of levetiracetam in children aged 10 years and younger: A clinical experience
    • Tan MJ, Appleton RE. Efficacy and tolerability of levetiracetam in children aged 10 years and younger: A clinical experience. Seizure 2004;13:142-145.
    • (2004) Seizure , vol.13 , pp. 142-145
    • Tan, M.J.1    Appleton, R.E.2
  • 52
    • 34247098912 scopus 로고    scopus 로고
    • Efficacy and tolerability of levetiracetam as adjunctive and monotherapy in pediatric epilepsy
    • Khurana DS, Kothare SV, Valencia I, et al. Efficacy and tolerability of levetiracetam as adjunctive and monotherapy in pediatric epilepsy. Epilepsia 2004;45:321.
    • (2004) Epilepsia , vol.45 , pp. 321
    • Khurana, D.S.1    Kothare, S.V.2    Valencia, I.3
  • 53
    • 0037232175 scopus 로고    scopus 로고
    • A paradoxical effect of levetiracetam may be seen in both children and adults with refractory epilepsy
    • Nakken KG, Eriksson AS, Lossius R, et al. A paradoxical effect of levetiracetam may be seen in both children and adults with refractory epilepsy. Seizure 2003;12:42-46.
    • (2003) Seizure , vol.12 , pp. 42-46
    • Nakken, K.G.1    Eriksson, A.S.2    Lossius, R.3
  • 54
    • 0025343921 scopus 로고
    • Gabapentin in partial epilepsy
    • UK Gabapentin Study Group
    • UK Gabapentin Study Group. Gabapentin in partial epilepsy. Lancet 1990;335:1114-1117.
    • (1990) Lancet , vol.335 , pp. 1114-1117
  • 55
    • 0027374164 scopus 로고
    • 5. Gabapentin as add-on therapy in refactory partial epilepsy: A double-blind, placebo-controlled, parallel-group study
    • The US Gabapentin Study Group No
    • The US Gabapentin Study Group No. 5. Gabapentin as add-on therapy in refactory partial epilepsy: A double-blind, placebo-controlled, parallel-group study. Neurology 1993;43:2292-2298.
    • (1993) Neurology , vol.43 , pp. 2292-2298
  • 56
    • 0028041242 scopus 로고
    • Gabapentin (neurontin) as add-on therapy in patients with partial seizures: A double-blind, placebo-controlled. The International Gabapentin Study Group
    • Anhut H, Ashman P, Feuerstein TJ, et al. Gabapentin (neurontin) as add-on therapy in patients with partial seizures: A double-blind, placebo-controlled. The International Gabapentin Study Group. Epilepsia 1994;35:795-801.
    • (1994) Epilepsia , vol.35 , pp. 795-801
    • Anhut, H.1    Ashman, P.2    Feuerstein, T.J.3
  • 57
    • 0032800766 scopus 로고    scopus 로고
    • Gabapentin as add-on therapy in children with refractory partial seizures: A 12 week, multicentre, double-blind, placebo-controlled study. Gabapentin Pediatric Study Group
    • Appelton R, Fichtner K, LaMoreaux L, et al. Gabapentin as add-on therapy in children with refractory partial seizures: A 12 week, multicentre, double-blind, placebo-controlled study. Gabapentin Pediatric Study Group. Epilepsia 1999;40:1147-1154.
    • (1999) Epilepsia , vol.40 , pp. 1147-1154
    • Appelton, R.1    Fichtner, K.2    LaMoreaux, L.3
  • 58
    • 16344368998 scopus 로고    scopus 로고
    • Meta-analysis and indirect comparisons of levetiracetam with other second-generation antiepileptic drugs in partial epilepsy
    • Otoul C, Arrigo C, van Rijckevorsel K, et al. Meta-analysis and indirect comparisons of levetiracetam with other second-generation antiepileptic drugs in partial epilepsy. Clin Neuropharmacol 2005;28:72-78.
    • (2005) Clin Neuropharmacol , vol.28 , pp. 72-78
    • Otoul, C.1    Arrigo, C.2    van Rijckevorsel, K.3
  • 59
    • 11144353969 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepileptic drugs II: Treatment of refractory epilepsy
    • French JA, Kanner AM, Bautista J, et al. Efficacy and tolerability of the new antiepileptic drugs II: Treatment of refractory epilepsy. Neurol 2004;62:1261-1273.
    • (2004) Neurol , vol.62 , pp. 1261-1273
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 60
    • 38949184571 scopus 로고    scopus 로고
    • Intravenous levetiracetam in children with epilepsy
    • Goraya JS, Khurana DS,Valencia I, et al. Intravenous levetiracetam in children with epilepsy. Pediatr Neurol 2008;38:177-180.
    • (2008) Pediatr Neurol , vol.38 , pp. 177-180
    • Goraya, J.S.1    Khurana, D.S.2    Valencia, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.