Perilesional neurochemical changes in focal epilepsies

Acta Neuropathologica

Volumn 91, Issue 4, 1996, Pages 376-384

  Wolf, Helmut K ^a   Roos, Dirk ^a   Blümcke, Ingmar ^a   Pietsch, Torsten ^a   Wiestler, Otmar D ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Epilepsy; Immunohistochemistry; Neurotransmitter; Pathology; Tumor

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; GLUTAMATE DECARBOXYLASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ARTICLE; BRAIN CORTEX LESION; CLINICAL ARTICLE; CONGENITAL BLOOD VESSEL MALFORMATION; FOCAL EPILEPSY; GLIOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NEUROCHEMISTRY; NEUROEPITHELIOMA; NEUROPATHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; SEIZURE;

EPILEPSIES, PARTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; NEUROTRANSMITTER AGENTS; RECEPTORS, GABA;

EID: 0030005209     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050439     Document Type: Article

References (45)

1. Avoli M (1988) GABAergic mechanisms and epileptic discharges. In: Avoli M, Reader TA, Dykes RW, Gloor P (eds) Neurotransmitters and cortical function: from molecules to mind. Plenum Press, New York, pp 187-205
2. Babb TL, Pretorias JK, Kupfer WR, Crandall PH (1989) Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J Neurosci 9: 2562-2574
3. Babb TL, Pretorius JK, Kupfer WR, Feldblum S (1989) Recovery of decreased glutamate decarboxylase immunoreactivity after rat hippocampal kindling. Epilepsy Res 3: 18-30
4. Bakay R, Harris A (1981) Neurotransmitter, receptor and biochemical changes in monkey cortical epileptic foci. Brain Res 206: 387-404
5. Bayer TA, Wiestler OD, Wolf HK (1995) Hippocampal loss of N-methyl-D-aspartate receptor subunit 1 mRNA in chronic temporal lobe epilepsy. Acta Neuropathol 89: 446-450
6. Bruton CJ (ed) (1988) The neuropathology of temporal lobe epilepsy. Oxford University Press, Oxford
7. Corsellis J (1970) The neuropathology of temporal lobe epilepsy. In: Williams D (ed) Modem trends in neurology, 5th edn. Butterworth, London, pp 254-270
8. DeFelipe J, Huntley GW, Del RM, Sola RG, Morrison JH (1994) Microzonal decreases in the immunostaining for non-NMDA ionotropic excitatory amino acid receptor subunits GluR 2/3 and GluR 5/6/7 in the human epileptogenic neocortex. Brain Res 657: 150-158
9. Elger CE, Schramm J (1993) Chirurgische Epilepsietherapie. Radiologe 33: 165-171
10. Engel J Jr (ed) (1993) Surgical treatment of the epilepsies, 2nd edn. Raven Press, New York
11. Geddes JW, Cahan LD, Cooper SM, Kim RC, Choi BH, Cotman CW (1990) Altered distribution of excitatory amino acid receptors in temporal lobe epilepsy. Exp Neurol 108: 214-220
12. Haglund MM, Berger MS, Kunkel DD, Franck JE, Ghatan S, Ojemann GA (1992) Changes in gamma-aminobutyric acid and somatostatin in epileptic cortex associated with low-grade gliomas. J Neurosurg 77: 209-216
13. Heinemann U (1987) Basic mechanisms of the epilepsies. In: Halliday AM, Butler SR, Paul R (eds) A textbook of clinical neurophysiology. Wiley, New York, pp 497-534
14. Hosford DA, Crain BJ, Cao Z, Bonhaus DW, Friedman AH, Okazaki MM, Nadler JV, McNamara JO (1991) Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus. J Neurosci 11: 428-434
15. Houser CR (1991) GABA neurons in seizure disorders: a review of immunocytochemical studies. Neurochem Res 16: 295-308
16. Houser CR, Harris AB, Vaughn JE (1986) The course of reduction of GABA terminals in a model of focal epilepsy: a glutamic acid decarboxylase immunohistochemical study. Brain Res 383: 129-145
17. Johnson EW, de Lanerolle NC, Kim JH, Sundaresan S, Spencer DD, Mattson RH, Zoghbi SS, Baldwin RM, Hoffer PB, Seibyl JP, Innis RB (1992) "Central" and "peripheral" benzodiazepine receptors: opposite changes in human epileptogenic tissue. Neurology 42: 811-815
18. Kleihues P, Burger PC, Scheithauer BW (eds) (1993) Histological typing of tumours of the central nervous system, 2nd edn. Springer, Berlin Heidelberg New York
19. Lloyd KG, Munari C, Bossi L, Stoeffels C, Talairach J, Morselli PL (1981) Biochemical evidence for alterations of GABA-mediated synaptic transmission in pathological brain tissue (stereo EEG or morphological definition) from epileptic patients. In: Morselli PL, Lloyd KG, Löscher W, Meldrum BS, Reynolds E (eds) Neurotransmitters, seizures and epilepsy. Raven Press, New York, pp 325-334
20. Lloyd KG, Bossi L, Morselli PL, Munari C, Rougier M, Loiseau H (1986) Alterations of GABA-mediated synaptic transmission in human epilepsy. Adv Neurol 44: 1033-1044
21. Lüders H (ed) (1992) Epilepsy surgery. Raven Press, New York
22. Mathem GW, Babb TL, Pretorius JK, Leite JP (1995) Reactive synaptogenesis and neuron densities for neuropeptide Y, somatostatin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata. J Neurosci 15: 3990-4004
23. McDonald JW, Garofalo EA, Hood T, Sackellares JC, Gilman S, McKeever PE, Troncoso JC, Johnston MV (1991) Altered excitatory and inhibitory amino acid receptor binding in hippocampus of patients with temporal lobe epilepsy. Ann Neurol 29: 529-541
24. Monyer H, Seeburg PH (1993) Constituents involved in glutamate receptor signaling. Hippocampus 3: 125-130
25. Morimoto K (1989) Seizure-triggering mechanisms in the kindling model of epilepsy: collapse of GABA-mediated inhibition and activation of NMDA receptors. Neurosci Biobehav Rev 13: 253-260
26. Perry T, Hansen S (1981) Amino acid abnormalities in epileptogenic foci. Neurology 31: 872-876
27. Ribak CE, Harris AB, Vaughn JE, Roberts E (1979) Inhibitory, GABAergic nerve terminals decrease at sites of focal epilepsy. Science 205: 211-214
28. Ribak CE, Hunt CA, Bakay RA, Oertel WH (1986) A decrease in the number of GABAergic somata is associated with the preferential loss of GABAergic terminals at epileptic foci. Brain Res 363: 78-90
29. Schwartzkroin PA (1993) Basic mechanisms of epileptogenesis. In: Wyllie E (ed) The treatment of epilepsy. Lea & Febiger, Philadelphia, pp 83-98
30. Schwartzkroin PA (1993) Basic research in the setting of an epilepsy surgery center. In: Engel J Jr (ed) Surgical treatment of the epilepsies, 2nd edn. Raven Press, New York, pp 755-773
31. Sherwin A, Quesney F, Gauthier S, Olivier A, Robitaille Y, McQuaid P, Harvey C, Van Gelder N (1984) Enzyme changes in actively spiking areas of human epileptic cortex. Neurology 34: 927-933
32. Sherwin A, Matthew E, Blain M, Guévremont D (1986) Benzodiazepine receptor binding is not altered in human epiletogenic cortical foci. Neurology 36: 1380-1382
33. Sherwin A, Robitaille, Quesney F, Olivier A, Villemure J, Leblanc R, Feindel W, Anderman E, Gotamn J, Anderman F, Ethier R, Kish S (1988) Excitatory amino acids are elevated in human epileptic cerebral cortex. Neurology 38: 920-923
34. Shivers BD, Killisch I, Sprengel R, Sontheimer H, Kohler M, Schofield PR, Seeburg PH (1989) Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. Neuron 3: 327-337
35. A-Benzodiazepinrezeptoren und Epilepsie. Wien Klin Wochenschr 102: 197-201
36. Snodgrass SR (1992) GABA and epilepsy: their complex relationship and the evolution of our understanding. J Child Neurol 7: 77-86
37. Spencer SS, Spencer DD (eds) (1991) Surgery for epilepsy. Blackwell, Boston
38. Van Gelder N, Sherwin A, Rasmussen T (1972) Amino acid content of epileptogenic human brain: focal versus surrounding regions. Brain Res 40: 385-393
39. Wisden W, Laurie DJ, Monyer H, Seeburg PH (1992) The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci 12: 1040-1062
40. Wolf HK, Wiestler OD (1993) Surgical pathology of chronic epileptic seizure disorders. Brain Pathol 3: 371-380
41. Wolf HK, Campos MG, Zentner J, Hufnagel A, Schramm J, Elger CE, Wiestler OD (1993) Surgical pathology of temporal lobe epilepsy. Experience with 216 cases. J Neuropathol Exp Neurol 52: 499-506
42. Wolf HK, Zentner J, Hufnagel A, Campos MG, Schramm J, Elger CE, Wiestler OD (1993) Surgical pathology of chronic epileptic seizure disorders: experience with 63 specimens from extratemporal corticectomies, lobectomies and functional hemispherectomies. Acta Neuropathol 86: 466-472
43. 1 subunit in patients with chronic pharmacoresistant epilepsies. Acta Neuropathol 88: 313-319
44. Yeh G-C, Bonhaus DW, Nadler JV, McNamara JO (1989) N-Methyl-D-aspartate receptor plasticity in kindling: quantitative and qualitative alterations in the N-methyl-D-aspartate receptor-channel. Proc Natl Acad Sci USA 86: 8157-8160
45. Zentner J, Hufnagel A, Wolf HK, Ostertun B, Behrens E, Campos MG, Solymosi L, Elger CE, Wiestler OD, Schramm J (1995) Surgical treatment of temporal lobe epilepsy: clinical, radiological and histopathological findings in 178 patients. J Neurol Neurosurg Psychiatry 58: 666-673