-
1
-
-
0028984234
-
Glucuronidation in the Caco-2 intestinal cell line: Induction of UDP-glucuronosyltransferase 1*6
-
Abid, A., Bouchon, I., Siest, G., Sabolovic, N. (1995). Glucuronidation in the Caco-2 intestinal cell line: induction of UDP-glucuronosyltransferase 1*6. Biochem Pharmacol 50:557-561.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 557-561
-
-
Abid, A.1
Bouchon, I.2
Siest, G.3
Sabolovic, N.4
-
2
-
-
59649117051
-
Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: An in vitro investigation of genetic and splice variants
-
Benoit-Biancamano, M. O., Connelly, J., Villeneuve, L., Caron, P., Guillemette, C. (2009). Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: an in vitro investigation of genetic and splice variants. Drug Metab Disp 37:322-329.
-
(2009)
Drug Metab Disp
, vol.37
, pp. 322-329
-
-
Benoit-Biancamano, M.O.1
Connelly, J.2
Villeneuve, L.3
Caron, P.4
Guillemette, C.5
-
3
-
-
0016208414
-
Oxidation of barbiturates and the glucuronidation of 1-naphthol in perfused rat liver and in microsomes
-
Bock, K. W. (1974). Oxidation of barbiturates and the glucuronidation of 1-naphthol in perfused rat liver and in microsomes. Naunyn-Schmiedeber's Arch Pharmacol 283:319-330.
-
(1974)
Naunyn-Schmiedeber's Arch Pharmacol
, vol.283
, pp. 319-330
-
-
Bock, K.W.1
-
4
-
-
0041930641
-
Vertebrate UDP-glucuronosyltransferases: Functional and evolutionary aspects
-
Bock, K. W. (2003). Vertebrate UDP-glucuronosyltransferases: functional and evolutionary aspects. Biochem Pharmacol 66:691-696.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 691-696
-
-
Bock, K.W.1
-
5
-
-
0023502543
-
Diferential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers
-
Bock, K. W., Bock-Hennig, B. S. (1987). Diferential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers. Biochem Pharmacol 36:4137-4143.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 4137-4143
-
-
Bock, K.W.1
Bock-Hennig, B.S.2
-
6
-
-
33745965633
-
Ah receptor: Dioxin-mediated toxic responses as hints to deregulated physiologic functions
-
Bock, K. W., Köhle, C. (2006). Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions. Biochem Pharmacol 72:393-404.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 393-404
-
-
Bock, K.W.1
Köhle, C.2
-
7
-
-
63149156351
-
Topological aspects of oligomeric UDP-glucuronosyltransferases in endoplasmic reticulum membranes: Advances and open questions
-
Bock, K. W., Köhle, C. (2009). Topological aspects of oligomeric UDP-glucuronosyltransferases in endoplasmic reticulum membranes: advances and open questions. Biochem Pharmacol 77:1458-1465.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 1458-1465
-
-
Bock, K.W.1
Köhle, C.2
-
8
-
-
0016196820
-
UDP-glucuronyltransferase in perfused rat liver and in microsomes: Infuence of phenobarbital and 3-methylcholanthrene
-
Bock, K. W., White, I. (1974). UDP-glucuronyltransferase in perfused rat liver and in microsomes: infuence of phenobarbital and 3-methylcholanthrene. Eur J Biochem 46:451-459.
-
(1974)
Eur J Biochem
, vol.46
, pp. 451-459
-
-
Bock, K.W.1
White, I.2
-
9
-
-
0033954736
-
Coordinate induction by antioxidants of UDP-glucuronosyltransferase UGT1A6 and the apical export pump, MRP2 (multidrug resistance protein 2), in Caco-2 cells
-
Bock, K. W., Eckle, T., Ouzzine, M., Fournel-Gigleux, S. (2000). Coordinate induction by antioxidants of UDP-glucuronosyltransferase UGT1A6 and the apical export pump, MRP2 (multidrug resistance protein 2), in Caco-2 cells. Biochem Pharmacol 59:467-470.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 467-470
-
-
Bock, K.W.1
Eckle, T.2
Ouzzine, M.3
Fournel-Gigleux, S.4
-
10
-
-
0027256828
-
Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases
-
Bock, K. W., Forster, A., Gschaidmeier H., Brück, M, Münzel, P., Scharek, W., Fournel-Gigleux, S., et al. (1993). Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases. Biochem Pharmacol 45:1809-1814.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 1809-1814
-
-
Bock, K.W.1
Forster, A.2
Gschaidmeier, H.3
Brück, M.4
Münzel, P.5
Scharek, W.6
Fournel-Gigleux, S.7
-
11
-
-
0015926539
-
Efects of phenobarbital and 3-methylcholanthrene on substrate specif-city of rat liver microsomal UDP-glucuronyltransferase
-
Bock, K. W., Fröhling, W., Remmer, H., Rexer, B. (1973). Efects of phenobarbital and 3-methylcholanthrene on substrate specif-city of rat liver microsomal UDP-glucuronyltransferase. Biochim Biophys Acta 327:46-56.
-
(1973)
Biochim Biophys Acta
, vol.327
, pp. 46-56
-
-
Bock, K.W.1
Fröhling, W.2
Remmer, H.3
Rexer, B.4
-
12
-
-
0027075077
-
Mono-and diglucuronide formation from chrysene and benzo(a) pyrene phenols by 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase (UGT1A1)
-
Bock, K. W., Gschaidmeier, H., Seidel, A., Baird, B., Burchell, B. (1992). Mono-and diglucuronide formation from chrysene and benzo(a)pyrene phenols by 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase (UGT1A1). Mol Pharmacol 42:613-618.
-
(1992)
Mol Pharmacol
, vol.42
, pp. 613-618
-
-
Bock, K.W.1
Gschaidmeier, H.2
Seidel, A.3
Baird, B.4
Burchell, B.5
-
13
-
-
0018747509
-
Purification of rat liver microsomal UDP-glucuronyltransferase: Separation of two enzyme forms inducible by 3-methylcholanthrene or phenobarbital
-
DOI 10.1111/j.1432-1033.1979.tb13155.x
-
Bock, K. W., Josting, D., Lilienblum, W., Pfeil, H. (1979). Purifcation of rat liver microsomal UDP-glucuronyltransferase. Separation of two enzyme forms inducible by 3-methylcholanthrene or phenobarbital. Eur J Biochem 98:19-26. (Pubitemid 9228899)
-
(1979)
European Journal of Biochemistry
, vol.98
, Issue.1
, pp. 19-26
-
-
Bock, K.W.1
Josting, D.2
Lilienblum, W.3
Pfeil, H.4
-
14
-
-
0020063940
-
Functional heterogeneity of UDP-glucuronosyltransferase activities in C57BL/6 and DBA/2 mice
-
Bock, K. W., Lilienblum, W., Pfeil, H. (1982). Functional heterogeneity of UDP-glucuronosyltransferase activities in C57BL/6 and DBA/2 mice. Biochem Pharmacol 31:1273-1277.
-
(1982)
Biochem Pharmacol
, vol.31
, pp. 1273-1277
-
-
Bock, K.W.1
Lilienblum, W.2
Pfeil, H.3
-
15
-
-
0021356092
-
Studies of UDP-glucuronyltransferase activities in human liver microsomes
-
Bock, K. W., Lilienblum, W., von Bahr, C. (1984). Studies of UDP-glucuroyltransferase activities in human liver microsomes. Drug Metab Disp 12:93-97. (Pubitemid 14189047)
-
(1984)
Drug Metabolism and Disposition
, vol.12
, Issue.1
, pp. 93-97
-
-
Bock, K.W.1
Lilienblum, W.2
Von Bahr, C.3
-
16
-
-
0025602894
-
Induction of drug-metabolizing enzymes by xenobiotics
-
Bock, K. W., Lipp, H. P., Bock-Hennig, B. S. (1990b). Induction of drug-metabolizing enzymes by xenobiotics. Xenobiotica 20:1101-1111.
-
(1990)
Xenobiotica
, vol.20
, pp. 1101-1111
-
-
Bock, K.W.1
Lipp, H.P.2
Bock-Hennig, B.S.3
-
17
-
-
0025301490
-
Persistently increased expression of a 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase in rat hepatocyte nodules and hepatocellular carcinomas
-
Bock, K. W., Münzel, P. A., Röhrdanz, E., Schrenk, D., Eriksson, L. C. (1990a). Persistently increased expression of a 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase in rat hepatocyte nodules and hepatocellular carcinomas. Cancer Res 50:3569-3573.
-
(1990)
Cancer Res
, vol.50
, pp. 3569-3573
-
-
Bock, K.W.1
Münzel, P.A.2
Röhrdanz, E.3
Schrenk, D.4
Eriksson, L.C.5
-
18
-
-
0023937867
-
Properties of a 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase from rat liver
-
Bock, K. W., Schirmer, G., Green, M. D., Tephly, T. R. (1988). Properties of a 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase from rat liver. Biochem Pharmacol 37:1439-1443.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1439-1443
-
-
Bock, K.W.1
Schirmer, G.2
Green, M.D.3
Tephly, T.R.4
-
19
-
-
0028018821
-
Te infuence of environmental and genetic factors on CYP2D6, CYP1A2, and UDP-glucuronosyltransferases in man using sparteine, cafeine, and paracetamol as probes
-
Bock, K. W., Schrenk, D., Forster, A., Griese, E. U., Mörike, K., Brockmeier, D., et al. (1994). Te infuence of environmental and genetic factors on CYP2D6, CYP1A2, and UDP-glucuronosyltransferases in man using sparteine, cafeine, and paracetamol as probes. Pharmacogenetics 4:209-218.
-
(1994)
Pharmacogenetics
, vol.4
, pp. 209-218
-
-
Bock, K.W.1
Schrenk, D.2
Forster, A.3
Griese, E.U.4
Mörike, K.5
Brockmeier, D.6
-
20
-
-
0023112104
-
Paracetamol as a test drug to determine glucuronide formation in man: Efects of inducers and of smoking
-
Bock, K. W., Wiltfang, J., Blume, R., Ullrich, D., Bircher J. (1987). Paracetamol as a test drug to determine glucuronide formation in man: efects of inducers and of smoking. Eur J Clin Pharmacol 31:677-683.
-
(1987)
Eur J Clin Pharmacol
, vol.31
, pp. 677-683
-
-
Bock, K.W.1
Wiltfang, J.2
Blume, R.3
Ullrich, D.4
Bircher, J.5
-
21
-
-
0037081788
-
Infuence of t-butylhydroquinone and β-naphthofavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/ TC-7 cell monolayers
-
Bock-Hennig, B. S., Köhle, C., Nill, K., Bock, K. W. (2002). Infuence of t-butylhydroquinone and β-naphthofavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/ TC-7 cell monolayers. Biochem Pharmacol 63:123-128.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 123-128
-
-
Bock-Hennig, B.S.1
Köhle, C.2
Nill, K.3
Bock, K.W.4
-
22
-
-
66449102968
-
Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specifc knockout of Ctnnb1
-
Braeuning, A., Sanna, R., Huelsken, J., Schwarz, M. (2009). Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specifc knockout of Ctnnb1. Drug Metab Disp 37:1138-1145.
-
(2009)
Drug Metab Disp
, vol.37
, pp. 1138-1145
-
-
Braeuning, A.1
Sanna, R.2
Huelsken, J.3
Schwarz, M.4
-
23
-
-
0343963108
-
In situ hybridization studies of UDP-glucuronosyltransferase UGT1A6 expression in rat testis and brain
-
Brands, A., Münzel, P. A., Bock, K. W. (2000). In situ hybridization studies of UDP-glucuronosyltransferase UGT1A6 expression in rat testis and brain. Biochem Pharmacol 59:1441-1444.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 1441-1444
-
-
Brands, A.1
Münzel, P.A.2
Bock, K.W.3
-
24
-
-
27844536927
-
Tissue-specifc, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus
-
Chen, S., Beaton, D., Nguyen, N., Senekeo-Efenberger, K., Brace-Sinnokrak, E., Argikar, U., et al. (2005). Tissue-specifc, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. J Biol Chem 280:37547-37557.
-
(2005)
J Biol Chem
, vol.280
, pp. 37547-37557
-
-
Chen, S.1
Beaton, D.2
Nguyen, N.3
Senekeo-Efenberger, K.4
Brace-Sinnokrak, E.5
Argikar, U.6
-
25
-
-
35548946775
-
Evidence for an aryl hydrocarbon receptor-mediated cytochrome P450 autoregulatory pathway
-
Chiaro, C. R., Patel, R. D., Marcus, C. B., Perdew, G. H. (2007). Evidence for an aryl hydrocarbon receptor-mediated cytochrome P450 autoregulatory pathway. Mol Pharmacol 72:1369-1379.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1369-1379
-
-
Chiaro, C.R.1
Patel, R.D.2
Marcus, C.B.3
Perdew, G.H.4
-
26
-
-
0035197725
-
Interindividual variability in acetaminophen glucuronidation by human liver microsomes: Identifca-tion of relevant acetaminophen UDP- glucuronosyltransferase isoforms
-
Court, M. H., Duan, S. X., von Moltke, L.L., Greenblatt, D. J., Patten, C. J., Miners, J. O., et al. (2001). Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identifca-tion of relevant acetaminophen UDP-glucuronosyltransferase isoforms. J Pharmacol Exp Ter 299:998-1006.
-
(2001)
J Pharmacol Exp ter
, vol.299
, pp. 998-1006
-
-
Court, M.H.1
Duan, S.X.2
Von Moltke, L.L.3
Greenblatt, D.J.4
Patten, C.J.5
Miners, J.O.6
-
27
-
-
0032806702
-
Part of quercetin absorbed in the small intestine is conjugated and further secreted in the intestinal lumen
-
Gastrointest Liver Physiol 40
-
Crespy, V., Morand, C., Manach, C., Besson, C., Demigne, C., Remesy, C. (1999). Part of quercetin absorbed in the small intestine is conjugated and further secreted in the intestinal lumen. Am J Physiol 277(Gastrointest Liver Physiol 40):G120-G126.
-
(1999)
Am J Physiol
, vol.277
-
-
Crespy, V.1
Morand, C.2
Manach, C.3
Besson, C.4
Demigne, C.5
Remesy, C.6
-
28
-
-
0016853644
-
Control of UDP-glucuronyltransferase activity
-
Dutton, G. J. (1975). Control of UDP-glucuronyltransferase activity. Biochem Pharmacol 24:1835-1841.
-
(1975)
Biochem Pharmacol
, vol.24
, pp. 1835-1841
-
-
Dutton, G.J.1
-
29
-
-
0030044294
-
Xenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complex
-
Emi, Y., Ikushiro, S., Iyanagi, T. (1996). Xenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complex. J Biol Chem 271:3952-3958.
-
(1996)
J Biol Chem
, vol.271
, pp. 3952-3958
-
-
Emi, Y.1
Ikushiro, S.2
Iyanagi, T.3
-
30
-
-
74549182860
-
Cytochrome P-450: Its function in the oxidative metabolism of drugs
-
Estabrook, R. W. (1971). Cytochrome P-450: its function in the oxidative metabolism of drugs. Handbook Exp Pharmacol 28:264-284.
-
(1971)
Handbook Exp Pharmacol
, vol.28
, pp. 264-284
-
-
Estabrook, R.W.1
-
31
-
-
0020858720
-
Separation, purifcation, and characterization of three isoenzymes of UDP-glucuronyltransferase from rat liver microsomes
-
Falany, C., Tephly, T. R. (1983). Separation, purifcation, and characterization of three isoenzymes of UDP-glucuronyltransferase from rat liver microsomes. Arch Biochem Biophys 227:248-258.
-
(1983)
Arch Biochem Biophys
, vol.227
, pp. 248-258
-
-
Falany, C.1
Tephly, T.R.2
-
32
-
-
0029000839
-
Immune system impairment and hepatic fbrosis in mice lacking the dioxin-binding Ah receptor
-
Fernandez-Salguero, P., Pineau, T., Hilbert, D. M., McPhail, T., Lee, S. S. T., Kimura, S., et al. (1995). Immune system impairment and hepatic fbrosis in mice lacking the dioxin-binding Ah receptor. Science 268:722-726.
-
(1995)
Science
, vol.268
, pp. 722-726
-
-
Fernandez-Salguero, P.1
Pineau, T.2
Hilbert, D.M.3
McPhail, T.4
Lee, S.S.T.5
Kimura, S.6
-
33
-
-
0028116221
-
Radiation inactivation analysis of microsomal UDP- glucuronosyltransferases catalyzing mono-and diglucuronide formation of 3,6-dihydroxybenzo(a) pyrene and 3,6-dihydroxychrysene
-
Gschaidmeier, H., Bock, K. W. (1994). Radiation inactivation analysis of microsomal UDP-glucuronosyltransferases catalyzing mono-and diglucuronide formation of 3,6-dihydroxybenzo(a) pyrene and 3,6-dihydroxychrysene. Biochem Pharmacol 48:1545-1549.
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 1545-1549
-
-
Gschaidmeier, H.1
Bock, K.W.2
-
34
-
-
0029051413
-
Formation of mono-and diglucuronides and other glycosides of benzo[a]pyrene-3,6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of the UGT1 gene complex
-
Gschaidmeier, H., Seidel, A., Burchell, B., Bock, K. W. (1995). Formation of mono-and diglucuronides and other glycosides of benzo[a]pyrene-3,6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of the UGT1 gene complex. Biochem Pharmacol 49:1601-1606.
-
(1995)
Biochem Pharmacol
, vol.49
, pp. 1601-1606
-
-
Gschaidmeier, H.1
Seidel, A.2
Burchell, B.3
Bock, K.W.4
-
35
-
-
0034116376
-
Te PAS super-family: Sensors of environmental and developmental signals
-
Gu, Y. Z., Hogenesch, J. B., Bradfeld, C. A. (2000). Te PAS super-family: sensors of environmental and developmental signals. Ann Rev Pharmacol Toxicol 40:519-561.
-
(2000)
Ann Rev Pharmacol Toxicol
, vol.40
, pp. 519-561
-
-
Gu, Y.Z.1
Hogenesch, J.B.2
Bradfeld, C.A.3
-
36
-
-
0011220356
-
Some factors afecting glucuronide formation in vitro
-
Inscoe, J. K., Axelrod, J. (1960). Some factors afecting glucuronide formation in vitro. J Pharmacol Exp Ter 129:128-131.
-
(1960)
J Pharmacol Exp ter
, vol.129
, pp. 128-131
-
-
Inscoe, J.K.1
Axelrod, J.2
-
37
-
-
0023019287
-
Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase
-
Iyanagi, T., Haniu, M., Sogawa, K., Fujii-Kuriyama, Y., Watanabe, S., Shively, J. E., et al. (1986). Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase. J Biol Chem 261:15607-15614.
-
(1986)
J Biol Chem
, vol.261
, pp. 15607-15614
-
-
Iyanagi, T.1
Haniu, M.2
Sogawa, K.3
Fujii-Kuriyama, Y.4
Watanabe, S.5
Shively, J.E.6
-
38
-
-
85039895931
-
Enhancement of glucuronide conjugating capacity in a hyperbilirubinemic infant due to apparent enzyme induction by phenobarbital
-
Jafe, S. J., Levy, D., Matsusawe, T., Baliah, T. (1966). Enhancement of glucuronide conjugating capacity in a hyperbilirubinemic infant due to apparent enzyme induction by phenobarbital. NEJM 275:461.
-
(1966)
NEJM
, vol.275
, pp. 461
-
-
Jafe, S.J.1
Levy, D.2
Matsusawe, T.3
Baliah, T.4
-
39
-
-
59149104736
-
AHR-mediated immunomudulation: The role of altered gene transcription
-
Kerkvliet, N. I. (2009). AHR-mediated immunomudulation: the role of altered gene transcription. Biochem Pharmacol 77:746-760.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 746-760
-
-
Kerkvliet, N.I.1
-
40
-
-
0033134122
-
Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identifcation of 5-hydroxytryptamine as a substrate
-
King, C. D., Rios, G. R., Assouline, J. A., Tephly, T. R. (1999). Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identifcation of 5-hydroxytryptamine as a substrate. Arch Biochem Biophys 365:156-162.
-
(1999)
Arch Biochem Biophys
, vol.365
, pp. 156-162
-
-
King, C.D.1
Rios, G.R.2
Assouline, J.A.3
Tephly, T.R.4
-
41
-
-
74549137501
-
Coordinate regulation of phase i and II xenobiotic metabolism by the Ah receptor and Nrf2
-
Köhle, C., Bock, K. W. (2007). Coordinate regulation of phase I and II xenobiotic metabolism by the Ah receptor and Nrf2. Biochem Pharmacol 72:795-805.
-
(2007)
Biochem Pharmacol
, vol.72
, pp. 795-805
-
-
Köhle, C.1
Bock, K.W.2
-
42
-
-
85058906540
-
Coordinate regulation of human drug-metabolizing enzymes and conjugate transporters by the Ah receptor, pregnane X receptor, and constitutive androstane receptor
-
Köhle, C., Bock, K. W. (2009). Coordinate regulation of human drug-metabolizing enzymes and conjugate transporters by the Ah receptor, pregnane X receptor, and constitutive androstane receptor. Biochem Pharmacol 73:1853-1862.
-
(2009)
Biochem Pharmacol
, vol.73
, pp. 1853-1862
-
-
Köhle, C.1
Bock, K.W.2
-
43
-
-
17044368235
-
Serotonin glucuronidation by Ah receptor-and oxidative stress-inducible human UDP-glucuronosyltransferase (UGT) 1A6 in Caco-2 cells
-
Köhle, C., Badary, O. A., Nill, K., Bock-Hennig, B. S., Bock, K. W. (2005). Serotonin glucuronidation by Ah receptor-and oxidative stress-inducible human UDP-glucuronosyltransferase (UGT) 1A6 in Caco-2 cells. Biochem Pharmacol 69:1397-1402.
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 1397-1402
-
-
Köhle, C.1
Badary, O.A.2
Nill, K.3
Bock-Hennig, B.S.4
Bock, K.W.5
-
44
-
-
50649098449
-
Promotion of hepato-carcinogenesis in humans and animal models
-
Köhle, C., Schwarz, M., Bock, K. W. (2008). Promotion of hepato-carcinogenesis in humans and animal models. Arch Toxicol 82:623-631.
-
(2008)
Arch Toxicol
, vol.82
, pp. 623-631
-
-
Köhle, C.1
Schwarz, M.2
Bock, K.W.3
-
45
-
-
0038685671
-
Validation of serotonin (5-hydroxytryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6
-
Krishnaswamy, S., Duan, S. X., von Moltke, L.L., Greenblatt, D. J., Court, M. H. (2003). Validation of serotonin (5-hydroxytryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6. Drug Metab Disp 31:133-139.
-
(2003)
Drug Metab Disp
, vol.31
, pp. 133-139
-
-
Krishnaswamy, S.1
Duan, S.X.2
Von Moltke, L.L.3
Greenblatt, D.J.4
Court, M.H.5
-
46
-
-
19444377994
-
UDP glucurono-syltransferase (UGT) 1A6 pharmacogenetics: I. Identifcation of polymorphisms in the 5'-regulatory and exon 1 regions, association with human liver UGT1A6 gene expression, and glucuroni-dation
-
Krishnaswamy, S., Hao, Q., Al-Rohaimi, A., Hesse, L. M., von Moltke, L. L., Greenblatt, D. J., et al. (2005a). UDP glucurono-syltransferase (UGT) 1A6 pharmacogenetics: I. Identifcation of polymorphisms in the 5'-regulatory and exon 1 regions, association with human liver UGT1A6 gene expression, and glucuroni-dation. J Pharmacol Exp Ter 313:1331-1339.
-
(2005)
J Pharmacol Exp ter
, vol.313
, pp. 1331-1339
-
-
Krishnaswamy, S.1
Hao, Q.2
Al-Rohaimi, A.3
Hesse, L.M.4
Von Moltke, L.L.5
Greenblatt, D.J.6
-
47
-
-
19444375984
-
UDP-glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UDP1A6 polymorphisms (S7A, T181A, and R184S)
-
Krishnaswamy, S., Hao, Q., Al-Rohaimi, A., Hesse, L. M., von Moltke, L.L., Greenblatt, D. J., et al. (2005b) UDP-glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UDP1A6 polymorphisms (S7A, T181A, and R184S). J Pharmacol Exp Ter 313:1340-1346.
-
(2005)
J Pharmacol Exp ter
, vol.313
, pp. 1340-1346
-
-
Krishnaswamy, S.1
Hao, Q.2
Al-Rohaimi, A.3
Hesse, L.M.4
Von Moltke, L.L.5
Greenblatt, D.J.6
-
48
-
-
0021953227
-
Protection against toxic redox cycles between benzo(a)pyrene-3,6-quinone and its quinol by 3-methylcholanthrene-inducible formation of the quinol mono-and diglucuronide
-
Lilienblum, W., Bock-Hennig, B. S., Bock, K. W. (1985). Protection against toxic redox cycles between benzo(a)pyrene-3,6-quinone and its quinol by 3-methylcholanthrene-inducible formation of the quinol mono-and diglucuronide. Mol Pharmacol 27:451-458.
-
(1985)
Mol Pharmacol
, vol.27
, pp. 451-458
-
-
Lilienblum, W.1
Bock-Hennig, B.S.2
Bock, K.W.3
-
49
-
-
4644315738
-
Glucuronidation of oxidized fatty acids and pros-taglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases
-
Little, J. M., Kurkela, M., Sonka, J., Jäntti, S., Ketola, R., Bratton, S., et al. (2004). Glucuronidation of oxidized fatty acids and pros-taglandins B1 and E2 by human hepatic and recombinant UDP- glucuronosyltransferases. J Lipid Res 45:1694-1703.
-
(2004)
J Lipid Res
, vol.45
, pp. 1694-1703
-
-
Little, J.M.1
Kurkela, M.2
Sonka, J.3
Jäntti, S.4
Ketola, R.5
Bratton, S.6
-
50
-
-
0023035858
-
Rat liver UDP-glucuronosyltransferase: Sequence and expression of a cDNA encoding a phenobarbital-inducible form
-
Mackenzie, P. I. (1986). Rat liver UDP-glucuronosyltransferase: sequence and expression of a cDNA encoding a phenobarbital-inducible form. J Biol Chem 261:6119-6125.
-
(1986)
J Biol Chem
, vol.261
, pp. 6119-6125
-
-
MacKenzie, P.I.1
-
51
-
-
25144500468
-
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily
-
Mackenzie, P. I., Bock, K. W., Burchell, B., Guillemette, C., Ikushiro, S., Iyanagi, T., et al. (2005). Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. Pharmacogenet Genom 15:677-685.
-
(2005)
Pharmacogenet Genom
, vol.15
, pp. 677-685
-
-
MacKenzie, P.I.1
Bock, K.W.2
Burchell, B.3
Guillemette, C.4
Ikushiro, S.5
Iyanagi, T.6
-
52
-
-
8544224973
-
Te UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
-
Mackenzie, P. I., Owens, I. S., Burchell, B., Bock, K. W., Bairoch, A., Belanger, A., et al. (1997). Te UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7:255-269.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 255-269
-
-
MacKenzie, P.I.1
Owens, I.S.2
Burchell, B.3
Bock, K.W.4
Bairoch, A.5
Belanger, A.6
-
53
-
-
0036765785
-
Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxifcation
-
Maglich, J. M., Stoltz, C. M., Goodwin, B., Hawkins-Brown, D., Moore, J. T., Kliewer, S. A. (2002). Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxifcation. Mol Pharmacol 62:638-646.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 638-646
-
-
Maglich, J.M.1
Stoltz, C.M.2
Goodwin, B.3
Hawkins-Brown, D.4
Moore, J.T.5
Kliewer, S.A.6
-
54
-
-
28844493391
-
New insights into biliverdin reductase functions: Linking heme metabolism to cell signaling
-
Maines, M. D. (2005). New insights into biliverdin reductase functions: linking heme metabolism to cell signaling. Physiology 20:382-389.
-
(2005)
Physiology
, vol.20
, pp. 382-389
-
-
Maines, M.D.1
-
55
-
-
0020533372
-
Revised methods for the Salmonella mutagenicity test
-
Maron, D. M., Ames, B. N. (1983). Revised methods for the Salmonella mutagenicity test. Mutat Res 113:173-215.
-
(1983)
Mutat Res
, vol.113
, pp. 173-215
-
-
Maron, D.M.1
Ames, B.N.2
-
56
-
-
0028314126
-
Tissue-specifc constitutive and inducible expression of rat phenol UDP-glucuronyltransferase
-
Münzel, P. A., Brück, M., Bock, K. W. (1994). Tissue-specifc constitutive and inducible expression of rat phenol UDP-glucuronyltransferase. Biochem Pharmacol 47:1445-1448.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 1445-1448
-
-
Münzel, P.A.1
Brück, M.2
Bock, K.W.3
-
57
-
-
0345486974
-
Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6
-
Münzel, P. A., Lehmköster, T., Brück, M., Ritter, J. K., Bock, K. W. (1998). Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6. Arch Biochem Biophys 350:72-78.
-
(1998)
Arch Biochem Biophys
, vol.350
, pp. 72-78
-
-
Münzel, P.A.1
Lehmköster, T.2
Brück, M.3
Ritter, J.K.4
Bock, K.W.5
-
58
-
-
17744408754
-
Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells
-
Münzel, P. A., Schmohl, S., Buckler, F., Jaehrling, J., Raschko, F. T., Köhle, C., et al. (2003). Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP- glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells. Biochem Pharmacol 66:841-847.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 841-847
-
-
Münzel, P.A.1
Schmohl, S.2
Buckler, F.3
Jaehrling, J.4
Raschko, F.T.5
Köhle, C.6
-
59
-
-
2642510760
-
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
-
Nebert, D. W., Dalton, T. P., Okey, A. B., Gonzalez, F. J. (2004). Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem 279:23847-23850.
-
(2004)
J Biol Chem
, vol.279
, pp. 23847-23850
-
-
Nebert, D.W.1
Dalton, T.P.2
Okey, A.B.3
Gonzalez, F.J.4
-
60
-
-
38949097735
-
Te search for endogenous activators of the aryl hydrocarbon receptor
-
Nguyen, L-P., Bradfeld, C. A. (2008). Te search for endogenous activators of the aryl hydrocarbon receptor. Chem Res Toxicol 21:102-116.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 102-116
-
-
Nguyen, L.-P.1
Bradfeld, C.A.2
-
61
-
-
0027978702
-
Glucuronidation of carcinogenic arylamines and their N-hydroxy derivatives by rat and human phenol UDP-glucuronosyltransferases of the UGT1 gene complex
-
Orzechowski, A., Schrenk, D., Bock-Hennig, B. S., Bock, K. W. (1994). Glucuronidation of carcinogenic arylamines and their N-hydroxy derivatives by rat and human phenol UDP-glucuronosyltransferases of the UGT1 gene complex. Carcinogenesis 15:1549-1553.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1549-1553
-
-
Orzechowski, A.1
Schrenk, D.2
Bock-Hennig, B.S.3
Bock, K.W.4
-
62
-
-
0017399329
-
Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice
-
Owens, I. S. (1977). Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. J Biol Chem 252:2827-2833.
-
(1977)
J Biol Chem
, vol.252
, pp. 2827-2833
-
-
Owens, I.S.1
-
63
-
-
34547481504
-
Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver
-
Patel, R. D., Hollingshead, B. D., Omiecinski, C. J., Perdew, G. H. (2007). Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. Mol Pharmacol 46:209-218.
-
(2007)
Mol Pharmacol
, vol.46
, pp. 209-218
-
-
Patel, R.D.1
Hollingshead, B.D.2
Omiecinski, C.J.3
Perdew, G.H.4
-
64
-
-
0032169723
-
Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin
-
Phelan, D., Winter, G. M., Rogers, W. J., Lam, J. C., Denison, M. S. (1998). Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. Arch Biochem Biophys 357:155-163.
-
(1998)
Arch Biochem Biophys
, vol.357
, pp. 155-163
-
-
Phelan, D.1
Winter, G.M.2
Rogers, W.J.3
Lam, J.C.4
Denison, M.S.5
-
65
-
-
0032791711
-
Expression and inducibility of the human bilirubin UDP- glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: Evidence for both genetic and environmental infuences
-
Ritter, J. K., Kessler, F. K., Tompson, M. T., Grove, A. D., Auyeung, D. J., Fisher, R. A. (1999). Expression and inducibility of the human bilirubin UDP-glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: evidence for both genetic and environmental infuences. Hepatology 30:476-484.
-
(1999)
Hepatology
, vol.30
, pp. 476-484
-
-
Ritter, J.K.1
Kessler, F.K.2
Tompson, M.T.3
Grove, A.D.4
Auyeung, D.J.5
Fisher, R.A.6
-
66
-
-
65249123179
-
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles
-
Sedlak, T. W., Saleh, M., Higginson, D. S., Paul, B. D., Juluri, K. R., Snyder, S. H. (2009). Bilirubin and glutathione have complementary antioxidant and cytoprotective roles. Proc Natl Acad Sci U S A 106:5171-5176.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5171-5176
-
-
Sedlak, T.W.1
Saleh, M.2
Higginson, D.S.3
Paul, B.D.4
Juluri, K.R.5
Snyder, S.H.6
-
67
-
-
0030861704
-
Aryl hydrocarbon receptor-dependent induction of CYP1a1 by bilirubin in mouse hepatoma Hepa 1c1c7 cells
-
Sinal, C. P., Bend, J. P. (1997). Aryl hydrocarbon receptor-dependent induction of CYP1a1 by bilirubin in mouse hepatoma Hepa 1c1c7 cells. Mol Pharmacol 52:590-599.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 590-599
-
-
Sinal, C.P.1
Bend, J.P.2
-
68
-
-
1642579667
-
An assessment of UGP-glucuronosyltransferase induction using primary human hepatocytes
-
Soars, M. G., Petullo, D. M., Eckstein, J. A., Kasper, S. C., Wrighton, S. A. (2004). An assessment of UGP-glucuronosyltransferase induction using primary human hepatocytes. Drug Metab Disp 32:140-148.
-
(2004)
Drug Metab Disp
, vol.32
, pp. 140-148
-
-
Soars, M.G.1
Petullo, D.M.2
Eckstein, J.A.3
Kasper, S.C.4
Wrighton, S.A.5
-
69
-
-
0016207478
-
Increase of chloramphenicol glucuronidation in rats treated with phenobarbital
-
Stramentinoli, G., Gazzaniga, A., Della Bella, D., Remmer, H. (1974). Increase of chloramphenicol glucuronidation in rats treated with phenobarbital. Biochem Pharmacol 23:1181-1186.
-
(1974)
Biochem Pharmacol
, vol.23
, pp. 1181-1186
-
-
Stramentinoli, G.1
Gazzaniga, A.2
Della Bella, D.3
Remmer, H.4
-
70
-
-
30144438495
-
Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor
-
DOI 10.1016/S0076-6879(05)00006-6, PII S0076687905000066, 6, Phase II Conjugation Enzymes and Transport Systems
-
Sugatani, J., Sueoshi, T., Negishi, M., Miva, M. (2005). Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocor-ticoid receptor. Meth Enzymol 400:92-104. (Pubitemid 43052417)
-
(2005)
Methods in Enzymology
, vol.400
, pp. 92-104
-
-
Sugatani, J.1
Sueyoshi, T.2
Negishi, M.3
Miwa, M.4
-
71
-
-
62149088599
-
Unveiling a new essential cis-element for transactivation of the CYP3A4 gene by xenobiotics
-
Toriyabe, T., Nagata, K., Takada T., Aratsu, Y., Matsubara, T., Yoshinari, K., et al. (2009). Unveiling a new essential cis-element for transactivation of the CYP3A4 gene by xenobiotics. Mol Pharmacol 75:677-684.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 677-684
-
-
Toriyabe, T.1
Nagata, K.2
Takada, T.3
Aratsu, Y.4
Matsubara, T.5
Yoshinari, K.6
-
72
-
-
0033051339
-
Transport of the favo-noid chrysin and its conjugated metabolites by the human intestinal cell line, Caco-2
-
Walle, U. K., Galijatovic, A., Walle, T. (1999). Transport of the favo-noid chrysin and its conjugated metabolites by the human intestinal cell line, Caco-2. Biochem Pharmacol 58:431-438.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 431-438
-
-
Walle, U.K.1
Galijatovic, A.2
Walle, T.3
-
73
-
-
0038236664
-
Involvement of the xenobiotic element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1
-
Yueh, M. F., Huang, Y. H., Hiller, A., Chen, S., Nguyen, N., Tukey, R. H. (2003). Involvement of the xenobiotic element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1. J Biol Chem 276:15001-15006
-
(2003)
J Biol Chem
, vol.276
, pp. 15001-15006
-
-
Yueh, M.F.1
Huang, Y.H.2
Hiller, A.3
Chen, S.4
Nguyen, N.5
Tukey, R.H.6
|