The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P11 groups

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 16, 2001, Pages 2189-2192

  Levin, J I ^a   Chen, J ^a   Du, M ^a   Hogan, M ^a   Kincaid, S ^a   Nelson, F C ^a   Venkatesan, A M ^a   Wehr, T ^a   Zask, A ^a   DiJoseph, J ^a   Killar, L M ^a   Skala, S ^a   Sung, A ^a   Sharr, M ^a   Roth, C ^a   Jin, G ^a   Cowling, R ^a   Mohler, K M ^b   Black, R A ^b   March, C J ^b   Skotnicki, J S ^a   more..

^a PFIZER INC   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID DERIVATIVE; CGS 27023A; COLLAGENASE 3; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE INHIBITOR; SULFONAMIDE HYDROXAMIC ACID INHIBITOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MUSCULOSKELETAL DISEASE; NONHUMAN; REACTION ANALYSIS;

ADAM PROTEINS; ANTHRANILIC ACIDS; COLLAGENASES; ENZYME INHIBITORS; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; METALLOENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 17944369447     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00419-X     Document Type: Article

References (22)