Increased notch 1 expression and attenuated stimulatory G protein coupling to adenylyl cyclase in osteonectin-null osteoblasts

Endocrinology

Volumn 148, Issue 4, 2007, Pages 1666-1674

  Kessler, Catherine B ^a   Delany, Anne M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ANABOLIC AGENT; CHOLERA TOXIN; CYCLIC AMP; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; NOTCH1 RECEPTOR; OSTEONECTIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; GENETIC LINKAGE; GENETIC TRANSCRIPTION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; ENZYME ACTIVATION; GTP-BINDING PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOBLASTS; OSTEONECTIN; PROTEIN BINDING; RECEPTOR, NOTCH1;

EID: 33947415689     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0443     Document Type: Article

References (52)

1. Haylock DN, Nilsson SK 2005 Stem cell regulation by the hematopoietic stem cell niche. Cell Cycle 4:1353-1355
2. Bi Y, Stuelten CH, Kilts T, Wadhwa S, Iozzo RV, Robey PG, Chen X-D, Young MF 2005 Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. J Biol Chem 280:30481-30489
3. Pizzo AM, Kokini K, Vaughn LC, Waisner BZ, Voytik-Harbin SL 2005 Extracellular matrix (ECM) microstructural composition regulates local cell-ECM biomechanics and fundamental fibroblast behavior: a multidimensional perspective. J Appl Physiol 98:1909-1921
4. Baluino A, Hurtado SP, Franzao P, Takiya CM, Alves LM, Nascuitti L-E, El-Cheikh MC, Borojevic R 2005 Bone marrow subendosteal microenvironment harbors functionally distinct haematosupportive stromal cell populations. Cell Tissue Res 319:255-266
5. Robey PG, Boskey AL 2003 Extracellular matrix and biomineralization of bone. In: Favus MJ, ed. Primer on the metabolic bone diseases and disorders of mineral metabolism. 5th ed. Washington, DC: American Society for Bone and Mineral Research; 38-46
6. Bradshaw AD, Sage EH 2001 SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury. J Clin Invest 107:1049-1054
7. Bradshaw AD, Puolakkainen P, Dasgupta J, JM Davidson, TN Wright, EH Sage 2003 SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength. J Invest Dermatol 120:949-955
8. Gooden MD, Vernon RB, Bassuk JA, Sage EH 1999 Cell cycle-dependent nuclear location of the matricellular protein SPARC: association with the nuclear matrix. J Cell Biochem 74:152-167
9. Brown TJ, Shaw PA, Karp X, Huynh M-H, Begley H, Ringuette MJ 1999 Activation of SPARC expression in reactive stroma associated with human epithelial ovarian cancer. Gynecol Oncol 75:25-33
10. Yan Q, Weaver M, Perdue N, Sage EH 2004 Matricellular protein SPARC is translocated to the nuclei of immortalized murine endothelial cells. J Cell Physiol 203:287-294
11. Huynh MH, Sodek K, Lee H, Ringuette M 2004 Interaction between SPARC and tubulin in Xenopus. Cell Tissue Res 317:313-317
12. Barker TH, Baneyx G, Cardo-Vila M, Workman GA, Weaver M, Menon PM, Dedhar S, Rempel SA, Arap W, Pasqualini R, Vogel V, Sage EH 2005 SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity. J Biol Chem 280:36483-36493
13. Norose K, Lo WK, Clark JI, Sage EH, Howe CC 2000 Lenses of SPARC-null mice exhibit an abnormal cell surface-basement membrane interface. Exp Eye Res 71:295-307
14. Bradshaw AD, Graves DC, Motamed K, Sage EH 2003 SPARC-null mice exhibit increased adiposity without significant differences in overall body weight. Proc Natl Acad Sci USA 100:6045-6050
15. Bradshaw AD, Reed MJ, Sage EH 2002 SPARC-null mice exhibit accelerated cutaneous wound closure. J Histochem Cytochem 50:1-10
16. Delany AM, Amling M, Priemel M, Howe C, Baron R, Canalis E 2000 Osteopenia and decreased bone formation in osteonectin-deficient mice. J Clin Invest 105:915-923
17. Delany AM, Kalajzic I, Bradshaw AD, Sage EH, Canalis E 2003 Osteonectin-null mutation compromises osteoblast formation, maturation, and survival. Endocrinology 144:2588-2596
18. Kadesch T 2004 Notch signaling: the demise of elegant simplicity. Curr Opin Genet Dev 14:506-512
19. Garces C, Ruiz-Hidalgo JM, Font de Mora J, Park C, Miele L, Goldstein J, Bonvini E, Porras A, Laborda J 1997 Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis. J Biol Chem 272:29729-29734
20. Ross DA, Rao PK, Kadesch T 2004 Dual roles for notch gene hes-1 in the differentiation of 3T3-L1 preadipocytes. Mol Cell Biol 24:3505-3513
21. Sciaudone M, Gazzerro E, Priest L, Delany AM, Canalis E 2003 Notch 1 impairs osteoblastic cell differentiation. Endocrinology 144:5631-5639
22. Deregowski V, Gazzerro E, Priest L, Rydziel S, Canalis E 2006 Notch1 overexpression inhibits osteoblastogenesis by suppressing wnt/β-catenin but not bone morphogenetic protein signaling. J Biol Chem 281:6203-6210
23. Nobta M, Tsukazaki T, Shibata Y, Xin C, Moriishi T, Sakano S, Shindo H, Yamaguchi A 2005 Critical regulation of bone morphogenic protein-induced osteoblastic differentiation by delta1/jagged1-activated notch signaling. J Biol Chem 280:15842-15848
24. Tezuka K, Yasuda M, Watanabe N, Morimura N, Kuroda K, Miyatani S, Hozumi N 2002 Stimulation of osteoblastic cell differentiation by notch. J Bone Miner Res 17:231-239
25. Pereira RMR, Delany AM, Durant D, Canalis E 2002 Cortisol regulates the expression of notch in osteoblasts. J Cell Biochem 85:252-258
26. Delany AM, Canalis E 1998 Basic fibroblast growth factor destabilizes osteonectin mRNA in osteoblasts. Am J Physiol 274:C734-C740
27. McCarthy TL, Centrella M, Canalis E 1988 Further biochemical and molecular characterization of primary rat parietal bone cell cultures. J Bone Miner Res 3:401-408
28. Lardelli M, Lendahl U 1993 Motch A and motch B - two mouse Notch homologs coexpressed in a wide variety of tissues. Exp Cell Res 204:364-372
29. Bolander ME, Young MF, Fisher LW, Yamada Y, Termine JD 1988 Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a serine proteinase inhibitor (ovomucoid). Proc Natl Acad Sci USA 85:2919-2923
30. Lian J, Stewart C, Puchacz E, Mackowia S, Shalhoub V, Zambetti G, Stein G 1989 Structure of the rat osteocalcin gene an regulation of vitamin D-dependent expression. Proc Natl Acad Sci USA 86:1143-1147
31. Oberbaumer I 1992 Retrotransposons do jump: a B2 element recently integrated in an 18S rRNA gene. Nucleic Acids Res 20:671-677
32. Lennon G, Auffray C, Polymeropoulo M, Soares MB 1996 The I.M.A.G.E. consortium: an integrated molecular analysis of genomes and their expression. Genomics 33:151-152
33. Harlow E, Lane D 1988 Antibodies: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 421-466
34. Delany AM 2001 Measuring transcription of metalloproteinase genes: nuclear run-off assay vs. analysis of hnRNA. Methods Mol Biol 151:321-333
35. Beatus P, Lundkvist J, Oberg C, Lendahl U 1999 The Notch 3 intracellular domain represses Notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters. Development 126:3925-3935
36. Zawel L, Dai JL, Buckhaults P, Zhou S, Kinzler KW, Vogelstein B, Kern SE 1998 Human smad3 and smad4 are sequence-specific transcription activators. Mol Cell 1:611-617
37. Carcamo J, Weis FM, Ventura F, Wieser R, Wrana JL, Attisano L, Massague J 1994 Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin. Moll Cell Biol 14:3810-3821
38. Donahue HJ, Zhou A, Li Z, McCauley LK 1997 Age related decreases in stimulatory G protein-coupled adenylate cyclase activity in osteoblasts. Am J Physiol 273:E776-E781
39. Blokzijl A, Dahlqvist C, Reissmann E, Falk A, Moliner A, Lendahl U, Ibanez CF 2003 Cross-talk between Notch and TGFβ signaling pathways mediated by interaction of the Notch intracellular domain with smad3. J Cell Biol 163:723-728
40. Francki A, McClure TD, Brekken RA, Motamed K, Murri C, Wang T, Sage EH 2004 SPARC regulates TGF-β1-dependent signaling in primary glomerular mesangial cells. J Cell Biochem 91:915-925
41. Schiemann BJ, Niel JR, Schiemann WP 2003 SPARC inhibits epithelial cell proliferation in part through stimulation of the transforming growth factor-β-signaling system. Mol Biol Cell 14:3977-3988
42. Bennett CN, Ross SE, Longo KA, Bajnok L, Hemati N, Johnson KW, Harrison SD, MacDougald OA 2002 Regulation of wnt signaling during adipogenesis. J Biol Chem 277:30998-31004
43. Narumiya S, FitzGerald GA 2001 Genetic and pharmacological analysis of prostanoid receptor function. J Clin Invest 108:25-30
44. Gensure RC, Gardella TJ, Juppner H 2005 Parathyroid hormone and parathyroid hormone-related peptide and their receptors. Biochem Biophys Research Com 328:666-678
45. de Souza NJ 1983 Forskolin: a labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory, and adenylate cyclase activating properties. Med Res Rev 3:201-219
46. Sofer A, Futerman AH 1995 Cationic amphiphilic drugs inhibit the internalization of cholera toxin to the Golgi apparatus and the subsequent elevation of cyclic AMP. J Biol Chem 270:12117-12122
47. Rosen CJ 2004 What's new with PTH in osteoporosis: where are we and where are we headed. Trends Endocrinol Metab 15:229-233
48. Ferrari SL, Pierroz DD, Glatt V, Goddard DS, Bianchi EN, Lin FT, Manen D, Bouxsein ML 2005 Bone response to intermittent parathyroid hormone is altered in mice null for β-arrestin2. Endocrinology 146:1854-1862
49. Ferraro SL, Bisello A 2001 Cellular distribution of constitutively active mutant parathyroid hormone (PTH)/PTH-related protein receptors and regulation of cyclic adenosine 3′,5′-monophosphate signaling by β-arrestin2. Mol Endocrinol 15:149-163
50. Pi M, Oakley RH, Gesty-Palemr D, Cruickshank RD, Spurney RF, Luttrell LM, Quarles LD 2005 β-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization. Mol Endocrinol 19:1078-1087
51. Chauvin X, Bencsik M, Bambino T, Nissenson RA 2002 Parathyroid hormone receptor recycling: role of receptor dephosphorylation and β-arrestin. Mol Endocrinol 16:2720-2732
52. Wang L, Liu S, Quarles LD, Spurney RF 2005 Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss. Am J Physiol Endocrinol Metab 288:E826-E834