메뉴 건너뛰기




Volumn 54, Issue 5, 2009, Pages 412-420

7-Difluoromethyl-5,4′-dimethoxygenistein, a novel genistein derivative, has therapeutic effects on atherosclerosis in a rabbit model

Author keywords

4 dimethoxygenistein; 7 difluoromethyl 5; Atherosclerosis; Genistein; Therapeutic effect

Indexed keywords

7 DIFLUOROMETHYL 5,4' DIMETHOXYGENISTEIN; CHOLESTEROL; COLLAGEN; GENISTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; UNCLASSIFIED DRUG;

EID: 74349099104     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e3181bad280     Document Type: Article
Times cited : (12)

References (48)
  • 1
    • 64749089721 scopus 로고    scopus 로고
    • Statins and cardiovascular diseases: From cholesterol lowering to pleiotropy
    • Zhou Q, Liao JK. Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy. Curr Pharm Des. 2009;15:467-478.
    • (2009) Curr Pharm des , vol.15 , pp. 467-478
    • Zhou, Q.1    Liao, J.K.2
  • 2
    • 23944443325 scopus 로고    scopus 로고
    • Effect of intensive lipid lowering on progression of coronary atherosclerosis: Evidence for an early benefit from the reversal of atherosclerosis with aggressive lipid lowering (REVERSAL) trial
    • Nissen SE. Effect of intensive lipid lowering on progression of coronary atherosclerosis: evidence for an early benefit from the reversal of atherosclerosis with aggressive lipid lowering (REVERSAL) trial. Am J Cardiol. 2005;96:F61-F68.
    • (2005) Am J Cardiol , vol.96
    • Nissen, S.E.1
  • 3
    • 57749092004 scopus 로고    scopus 로고
    • The pathology of atherosclerosis: Plaque development and plaque responses to medical treatment
    • Insull W Jr. The pathology of atherosclerosis: plaque development and plaque responses to medical treatment. Am J Med. 2009;122(Suppl 1): S3-S14.
    • (2009) Am J Med , vol.122 , Issue.SUPPL. 1
    • Insull Jr., W.1
  • 4
    • 42549141808 scopus 로고    scopus 로고
    • Cumulative clinical trial data on atorvastatin for reducing cardiovascular events: The clinical impact of atorvastatin
    • Bybee KA, Lee JH, O#Keefe JH. Cumulative clinical trial data on atorvastatin for reducing cardiovascular events: the clinical impact of atorvastatin. Curr Med Res Opin. 2008;24:1217-1229.
    • (2008) Curr Med Res Opin , vol.24 , pp. 1217-1229
    • Bybee, K.A.1    Lee, J.H.2    O'Keefe, J.H.3
  • 5
    • 3342996744 scopus 로고    scopus 로고
    • Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study
    • Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study Investigators
    • Kinlay S, Schwartz GG, Olsson AG, et al; Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study Investigators. Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study. Circulation. 2004;110:386-391.
    • (2004) Circulation , vol.110 , pp. 386-391
    • Kinlay, S.1    Schwartz, G.G.2    Olsson, A.G.3
  • 6
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: A randomized placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomized placebo-controlled trial. Lancet. 2002;360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 7
    • 59649121269 scopus 로고    scopus 로고
    • Other therapies for reducing low-density lipoprotein cholesterol: Medications in development
    • Stein EA. Other therapies for reducing low-density lipoprotein cholesterol: medications in development. Endocrinol Metab Clin North Am. 2009;38:99-119.
    • (2009) Endocrinol Metab Clin North Am , vol.38 , pp. 99-119
    • Stein, E.A.1
  • 8
    • 38849083283 scopus 로고    scopus 로고
    • Efficacy and tolerability of fluvastatin XL 80 mg alone, ezetimibe alone, and the combination of fluvastatin XL 80 mg with ezetimibe in patients with a history of musclerelated side effects with other statins
    • Stein EA, Ballantyne CM, Windler E, et al. Efficacy and tolerability of fluvastatin XL 80 mg alone, ezetimibe alone, and the combination of fluvastatin XL 80 mg with ezetimibe in patients with a history of musclerelated side effects with other statins. Am J Cardiol. 2008;101:490-496.
    • (2008) Am J Cardiol , vol.101 , pp. 490-496
    • Stein, E.A.1    Ballantyne, C.M.2    Windler, E.3
  • 9
    • 35548980921 scopus 로고    scopus 로고
    • Phytochemical genistein in the regulation of vascular function: New insights
    • Si H, Liu D. Phytochemical genistein in the regulation of vascular function: new insights. Curr Med Chem. 2007;14:2581-2589.
    • (2007) Curr Med Chem , vol.14 , pp. 2581-2589
    • Si, H.1    Liu, D.2
  • 10
    • 33750815738 scopus 로고    scopus 로고
    • Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis
    • Yamaguchi M. Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis. Yakugaku Zasshi. 2006;126:1117-1137.
    • (2006) Yakugaku Zasshi , vol.126 , pp. 1117-1137
    • Yamaguchi, M.1
  • 11
    • 35448942379 scopus 로고    scopus 로고
    • Implications of phytoestrogen intake for breast cancer
    • Duffy C, Perez K, Partridge A. Implications of phytoestrogen intake for breast cancer. CA Cancer J Clin. 2007;57:260-277.
    • (2007) CA Cancer J Clin , vol.57 , pp. 260-277
    • Duffy, C.1    Perez, K.2    Partridge, A.3
  • 12
    • 39149087699 scopus 로고    scopus 로고
    • Soy isoflavone genistein in prevention and treatment of prostate cancer
    • Perabo FG, Von Löw EC, Ellinger J, et al. Soy isoflavone genistein in prevention and treatment of prostate cancer. Prostate Cancer Prostatic Dis. 2008;11:6-12.
    • (2008) Prostate Cancer Prostatic Dis , vol.11 , pp. 6-12
    • Perabo, F.G.1    Von Löw, E.C.2    Ellinger, J.3
  • 13
    • 31544442153 scopus 로고    scopus 로고
    • Soy protein containing isoflavones reduces the size of atherosclerotic plaques without affecting coronary artery reactivity in adult male monkeys
    • Adams MR, Golden DL, Williams JK, et al. Soy protein containing isoflavones reduces the size of atherosclerotic plaques without affecting coronary artery reactivity in adult male monkeys. J Nutr. 2005;135: 2852-2856.
    • (2005) J Nutr , vol.135 , pp. 2852-2856
    • Adams, M.R.1    Golden, D.L.2    Williams, J.K.3
  • 14
    • 39149108167 scopus 로고    scopus 로고
    • Dietary isoflavones in the prevention of cardiovascular disease-a molecular perspective
    • Rimbach G, Boesch-Saadatmandi C, Frank J, et al. Dietary isoflavones in the prevention of cardiovascular disease-a molecular perspective. Food Chem Toxicol. 2008;46:1308-1319.
    • (2008) Food Chem Toxicol , vol.46 , pp. 1308-1319
    • Rimbach, G.1    Boesch-Saadatmandi, C.2    Frank, J.3
  • 15
    • 0036073599 scopus 로고    scopus 로고
    • Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability
    • Setchell KD, Brown NM, Zimmer-Nechemias L, et al. Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability. Am J Clin Nutr. 2002;76:447-453.
    • (2002) Am J Clin Nutr , vol.76 , pp. 447-453
    • Setchell, K.D.1    Brown, N.M.2    Zimmer-Nechemias, L.3
  • 16
    • 0037561244 scopus 로고    scopus 로고
    • Bioavailability of phytooestrogens
    • Rowland I, Faughnan M, Hoey L, et al. Bioavailability of phytooestrogens. Br J Nutr. 2003;89(Suppl 1):S45-S58.
    • (2003) Br J Nutr , vol.89 , Issue.SUPPL. 1
    • Rowland, I.1    Faughnan, M.2    Hoey, L.3
  • 17
    • 38149090233 scopus 로고    scopus 로고
    • Synthesis of genistein derivatives and determination of their protective effects against vascular endothelial cell damages caused by hydrogen peroxide
    • Fu XH, Wang L, Zhao H, et al. Synthesis of genistein derivatives and determination of their protective effects against vascular endothelial cell damages caused by hydrogen peroxide. Bioorg Med Chem Lett. 2008;18: 513-517.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 513-517
    • Fu, X.H.1    Wang, L.2    Zhao, H.3
  • 18
    • 0023787478 scopus 로고
    • Effects of diltiazem on suppression and regression of experimental atherosclerosis
    • Sugano M, Nakashima Y, Tasaki H, et al. Effects of diltiazem on suppression and regression of experimental atherosclerosis. Br J Exp Pathol. 1988;69:515-523.
    • (1988) Br J Exp Pathol , vol.69 , pp. 515-523
    • Sugano, M.1    Nakashima, Y.2    Tasaki, H.3
  • 19
    • 39449121917 scopus 로고    scopus 로고
    • Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed
    • Prasad K. Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Atherosclerosis. 2008;197:34-42.
    • (2008) Atherosclerosis , vol.197 , pp. 34-42
    • Prasad, K.1
  • 20
    • 0032563650 scopus 로고    scopus 로고
    • Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal
    • Kockx MM, De Meyer GR, Buyssens N, et al. Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal. Circ Res. 1998;83:378-387.
    • (1998) Circ Res , vol.83 , pp. 378-387
    • Kockx, M.M.1    De Meyer, G.R.2    Buyssens, N.3
  • 21
    • 0035692098 scopus 로고    scopus 로고
    • Possibilities of regression in arteriosclerosis
    • Metz S, Riedmüller K, Kinscherf R, et al. Possibilities of regression in arteriosclerosis. Z Gerontol Geriatr. 2001;34:466-469.
    • (2001) Z Gerontol Geriatr , vol.34 , pp. 466-469
    • Metz, S.1    Riedmüller, K.2    Kinscherf, R.3
  • 22
    • 34248199903 scopus 로고    scopus 로고
    • Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism
    • Prasad K, Lee P. Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism. Atherosclerosis. 2007;192:313-322.
    • (2007) Atherosclerosis , vol.192 , pp. 313-322
    • Prasad, K.1    Lee, P.2
  • 23
    • 0032006237 scopus 로고    scopus 로고
    • Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid
    • Prasad K, Mantha SV, Muir AD, et al. Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid. Atherosclerosis. 1998;136:367-375.
    • (1998) Atherosclerosis , vol.136 , pp. 367-375
    • Prasad, K.1    Mantha, S.V.2    Muir, A.D.3
  • 24
    • 0033574164 scopus 로고    scopus 로고
    • Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed
    • Prasad K. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Circulation. 1999;99:1355-1362.
    • (1999) Circulation , vol.99 , pp. 1355-1362
    • Prasad, K.1
  • 25
    • 0028925078 scopus 로고
    • Atherosclerosis: Basic mechanisms. Oxidation, inflammation, and genetics
    • Berliner JA, Navab M, Fogelman AM, et al. Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. Circulation. 1995; 91:2488-2496.
    • (1995) Circulation , vol.91 , pp. 2488-2496
    • Berliner, J.A.1    Navab, M.2    Fogelman, A.M.3
  • 26
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 2000;87:840-844.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 27
    • 30544453439 scopus 로고    scopus 로고
    • Molecular aspects of atherogenesis: New insights and unsolved questions
    • Puddu GM, Cravero E, Arnone G, et al. Molecular aspects of atherogenesis: new insights and unsolved questions. J Biomed Sci. 2005;12:839-853.
    • (2005) J Biomed Sci , vol.12 , pp. 839-853
    • Puddu, G.M.1    Cravero, E.2    Arnone, G.3
  • 28
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med. 1999; 340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 29
    • 0031793153 scopus 로고    scopus 로고
    • The role of reactive oxygen species in atherosclerosis
    • Mügge A. The role of reactive oxygen species in atherosclerosis. Z Kardiol. 1998;87:851-864.
    • (1998) Z Kardiol , vol.87 , pp. 851-864
    • Mügge, A.1
  • 30
    • 0037469232 scopus 로고    scopus 로고
    • Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association
    • Centers for Disease Control and Prevention; American Heart Association
    • Pearson TA, Mensah GA, Alexander RW, et al; Centers for Disease Control and Prevention; American Heart Association. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation. 2003;107:499-511.
    • (2003) Circulation , vol.107 , pp. 499-511
    • Pearson, T.A.1    Mensah, G.A.2    Alexander, R.W.3
  • 31
    • 0028909230 scopus 로고
    • Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris
    • European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group
    • Thompson SG, Kienast J, Pyke SD, et al. Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. N Engl J Med. 1995;332:635-641.
    • (1995) N Engl J Med , vol.332 , pp. 635-641
    • Thompson, S.G.1    Kienast, J.2    Pyke, S.D.3
  • 32
    • 1842587885 scopus 로고    scopus 로고
    • C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease
    • Danesh J, Wheeler JG, Hirschfield GM, et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med. 2004;350:1387-1397.
    • (2004) N Engl J Med , vol.350 , pp. 1387-1397
    • Danesh, J.1    Wheeler, J.G.2    Hirschfield, G.M.3
  • 33
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker PM, Hennekens CH, Buring JE, et al. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836-843.
    • (2000) N Engl J Med , vol.342 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3
  • 34
    • 33845405725 scopus 로고    scopus 로고
    • Anti-inflammatory effects of different drugs/agents with antioxidant property on endothelial expression of adhesion molecules
    • Chen YH, Lin SJ, Chen YL, et al. Anti-inflammatory effects of different drugs/agents with antioxidant property on endothelial expression of adhesion molecules. Cardiovasc Hematol Disord Drug Targets. 2006;6: 279-304.
    • (2006) Cardiovasc Hematol Disord Drug Targets , vol.6 , pp. 279-304
    • Chen, Y.H.1    Lin, S.J.2    Chen, Y.L.3
  • 35
    • 60349083949 scopus 로고    scopus 로고
    • 7-Difluoromethyl-5,4#-dimethoxygenistein inhibits oxidative stress induced adhesion between endothelial cells and monocytes via NF-kappaB
    • Wang L, Zheng X, Xiang HL, et al. 7-Difluoromethyl-5,4#- dimethoxygenistein inhibits oxidative stress induced adhesion between endothelial cells and monocytes via NF-kappaB. Eur J Pharmacol. 2009;605:31-35.
    • (2009) Eur J Pharmacol , vol.605 , pp. 31-35
    • Wang, L.1    Zheng, X.2    Xiang, H.L.3
  • 36
    • 0027125530 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes
    • Fuster V, Badimon L, Badimon JJ, et al. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med. 1992; 326:310-318.
    • (1992) N Engl J Med , vol.326 , pp. 310-318
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3
  • 37
    • 22144480077 scopus 로고    scopus 로고
    • Atherosclerosis and acute coronary syndromes
    • Gotlieb AI. Atherosclerosis and acute coronary syndromes. Cardiovasc Pathol. 2005;14:181-184.
    • (2005) Cardiovasc Pathol , vol.14 , pp. 181-184
    • Gotlieb, A.I.1
  • 38
    • 0642345202 scopus 로고    scopus 로고
    • Regulation of smooth muscle cell growth, function and death in vitro by activated mast cells-a potential mechanism for the weakening and rupture of atherosclerotic plaques
    • Leskinen MJ, Kovanen PT, Lindstedt KA. Regulation of smooth muscle cell growth, function and death in vitro by activated mast cells-a potential mechanism for the weakening and rupture of atherosclerotic plaques. Biochem Pharmacol. 2003;66:1493-1498.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1493-1498
    • Leskinen, M.J.1    Kovanen, P.T.2    Lindstedt, K.A.3
  • 39
    • 0036892838 scopus 로고    scopus 로고
    • Vulnerable plaque: The pathology of unstable coronary lesions
    • Virmani R, Burke AP, Kolodgie FD, et al. Vulnerable plaque: the pathology of unstable coronary lesions. J Interv Cardiol. 2002;15: 439-446.
    • (2002) J Interv Cardiol , vol.15 , pp. 439-446
    • Virmani, R.1    Burke, A.P.2    Kolodgie, F.D.3
  • 40
    • 0033054037 scopus 로고    scopus 로고
    • Atherosclerotic plaque rupture-pathologic basis of plaque stability and instability
    • van der Wal AC, Becker AE. Atherosclerotic plaque rupture-pathologic basis of plaque stability and instability. Cardiovasc Res. 1999;41: 334-344.
    • (1999) Cardiovasc Res , vol.41 , pp. 334-344
    • Van Der Wal, A.C.1    Becker, A.E.2
  • 41
    • 0345465669 scopus 로고    scopus 로고
    • Evidence for increased collagenolysis by interstitial collagenases-1 and-3 in vulnerable human atheromatous plaques
    • Sukhova GK, Schönbeck U, Rabkin E, et al. Evidence for increased collagenolysis by interstitial collagenases-1 and-3 in vulnerable human atheromatous plaques. Circulation. 1999;99:2503-2509.
    • (1999) Circulation , vol.99 , pp. 2503-2509
    • Sukhova, G.K.1    Schönbeck, U.2    Rabkin, E.3
  • 42
    • 18444391234 scopus 로고    scopus 로고
    • Statin-induced vascular smooth muscle cell apoptosis: A possible role in the prevention of restenosis?
    • Erl W. Statin-induced vascular smooth muscle cell apoptosis: a possible role in the prevention of restenosis? Curr Drug Targets Cardiovasc Haematol Disord. 2005;5:135-144.
    • (2005) Curr Drug Targets Cardiovasc Haematol Disord , vol.5 , pp. 135-144
    • Erl, W.1
  • 43
    • 0035916305 scopus 로고    scopus 로고
    • Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits
    • Fukumoto Y, Libby P, Rabkin E, et al. Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. Circulation. 2001;103:993-999.
    • (2001) Circulation , vol.103 , pp. 993-999
    • Fukumoto, Y.1    Libby, P.2    Rabkin, E.3
  • 44
    • 34247347733 scopus 로고    scopus 로고
    • Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation
    • Ferri N, Colombo G, Ferrandi C, et al. Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation. Arterioscler Thromb Vasc Biol. 2007;27:1043-1049.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1043-1049
    • Ferri, N.1    Colombo, G.2    Ferrandi, C.3
  • 46
    • 43549117004 scopus 로고    scopus 로고
    • Genistein attenuates oxidative stress and neuronal damage following transient global cerebral ischemia in rat hippocampus
    • Liang HW, Qiu SF, Shen J, et al. Genistein attenuates oxidative stress and neuronal damage following transient global cerebral ischemia in rat hippocampus. Neurosci Lett. 2008;438:116-120.
    • (2008) Neurosci Lett , vol.438 , pp. 116-120
    • Liang, H.W.1    Qiu, S.F.2    Shen, J.3
  • 47
    • 0033999603 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of biodegradable enoxacin microspheres
    • Abazinge M, Jackson T, Yang Q, et al. In vitro and in vivo characterization of biodegradable enoxacin microspheres. Eur J Pharm Biopharm. 2000; 49:191-194.
    • (2000) Eur J Pharm Biopharm , vol.49 , pp. 191-194
    • Abazinge, M.1    Jackson, T.2    Yang, Q.3
  • 48
    • 0035282638 scopus 로고    scopus 로고
    • C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance
    • Comte G, Daskiewicz JB, Bayet C, et al. C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance. J Med Chem. 2001;44:763-768.
    • (2001) J Med Chem , vol.44 , pp. 763-768
    • Comte, G.1    Daskiewicz, J.B.2    Bayet, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.