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Volumn 48, Issue 2, 2010, Pages 279-282

An antidote for calcium leak: Targeting molecular arrhythmia mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

4 [3 (4 BENZYL 1 PIPERIDINYL)PROPIONYL] 2,3,4,5 TETRAHYDRO 7 METHOXY 1,4 BENZOTHIAZEPINE; CAFFEINE; CALCIUM BINDING PROTEIN; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CALSEQUESTRIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; FLECAINIDE; RYANODINE RECEPTOR 2; S 107; SODIUM ION; TETRACAINE; UNCLASSIFIED DRUG;

EID: 74349096329     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.11.005     Document Type: Editorial
Times cited : (5)

References (31)
  • 1
    • 0024324830 scopus 로고
    • Cellular origins of the transient inward current in cardiac myocytes. Role of fluctuations and waves of elevated intracellular calcium
    • Berlin J.R., Cannell M.B., and Lederer W.J. Cellular origins of the transient inward current in cardiac myocytes. Role of fluctuations and waves of elevated intracellular calcium. Circ Res 65 (1989) 115-126
    • (1989) Circ Res , vol.65 , pp. 115-126
    • Berlin, J.R.1    Cannell, M.B.2    Lederer, W.J.3
  • 2
    • 0018651774 scopus 로고
    • Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle
    • Eisner D.A., and Lederer W.J. Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle. J Physiol (Lond) 294 (1979) 255-277
    • (1979) J Physiol (Lond) , vol.294 , pp. 255-277
    • Eisner, D.A.1    Lederer, W.J.2
  • 3
    • 0018198761 scopus 로고
    • Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres
    • Kass R.S., Lederer W.J., Tsien R.W., and Weingart R. Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres. J Physiol (Lond) 281 (1978) 187-208
    • (1978) J Physiol (Lond) , vol.281 , pp. 187-208
    • Kass, R.S.1    Lederer, W.J.2    Tsien, R.W.3    Weingart, R.4
  • 4
    • 0017031594 scopus 로고
    • Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibers
    • Lederer W.J., and Tsien R.W. Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibers. J Physiol (Lond) 263 (1976) 73-100
    • (1976) J Physiol (Lond) , vol.263 , pp. 73-100
    • Lederer, W.J.1    Tsien, R.W.2
  • 5
    • 0023155642 scopus 로고
    • Cellular and subcellular heterogeneity of [Ca2+]i in single heart cells revealed by fura-2
    • Wier W.G., Cannell M.B., Berlin J.R., Marban E., and Lederer W.J. Cellular and subcellular heterogeneity of [Ca2+]i in single heart cells revealed by fura-2. Science 235 (1987) 325-328
    • (1987) Science , vol.235 , pp. 325-328
    • Wier, W.G.1    Cannell, M.B.2    Berlin, J.R.3    Marban, E.4    Lederer, W.J.5
  • 6
    • 0015894415 scopus 로고
    • Effect of calcium on acetylstrophanthidin-induced transient depolarizations in canine Purkinje tissue
    • Ferrier G.R., and Moe G.K. Effect of calcium on acetylstrophanthidin-induced transient depolarizations in canine Purkinje tissue. Circ Res 33 (1973) 508-515
    • (1973) Circ Res , vol.33 , pp. 508-515
    • Ferrier, G.R.1    Moe, G.K.2
  • 7
    • 45749100010 scopus 로고    scopus 로고
    • Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice
    • Lehnart S.E., Mongillo M., Bellinger A., Lindegger N., Chen B.X., Hsueh W., et al. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. J Clin Invest 118 (2008) 2230-2245
    • (2008) J Clin Invest , vol.118 , pp. 2230-2245
    • Lehnart, S.E.1    Mongillo, M.2    Bellinger, A.3    Lindegger, N.4    Chen, B.X.5    Hsueh, W.6
  • 8
    • 36048981858 scopus 로고    scopus 로고
    • Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function
    • Lehnart S.E., Ackerman M.J., Benson Jr. D.W., Brugada R., Clancy C.E., Donahue J.K., et al. Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation 116 (2007) 2325-2345
    • (2007) Circulation , vol.116 , pp. 2325-2345
    • Lehnart, S.E.1    Ackerman, M.J.2    Benson Jr., D.W.3    Brugada, R.4    Clancy, C.E.5    Donahue, J.K.6
  • 9
  • 10
    • 35449001639 scopus 로고    scopus 로고
    • Regulation of ryanodine receptors in the heart
    • Lehnart S., and Marks A.R. Regulation of ryanodine receptors in the heart. Circ Res 101 (2007) 746-749
    • (2007) Circ Res , vol.101 , pp. 746-749
    • Lehnart, S.1    Marks, A.R.2
  • 13
    • 0025259588 scopus 로고
    • Interactions of flecainide with guinea pig cardiac sodium channels. Importance of activation unblocking to the voltage dependence of recovery
    • Anno T., and Hondeghem L.M. Interactions of flecainide with guinea pig cardiac sodium channels. Importance of activation unblocking to the voltage dependence of recovery. Circ Res 66 (1990) 789-803
    • (1990) Circ Res , vol.66 , pp. 789-803
    • Anno, T.1    Hondeghem, L.M.2
  • 14
    • 64149085800 scopus 로고    scopus 로고
    • Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans
    • Watanabe H., Chopra N., Laver D., Hwang H.S., Davies S.S., Roach D.E., et al. Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans. Nat Med 15 (2009) 380-383
    • (2009) Nat Med , vol.15 , pp. 380-383
    • Watanabe, H.1    Chopra, N.2    Laver, D.3    Hwang, H.S.4    Davies, S.S.5    Roach, D.E.6
  • 15
    • 33748292955 scopus 로고    scopus 로고
    • Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia
    • Knollmann B.C., Chopra N., Hlaing T., Akin B., Yang T., Ettensohn K., et al. Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia. J Clin Invest 116 (2006) 2510-2520
    • (2006) J Clin Invest , vol.116 , pp. 2510-2520
    • Knollmann, B.C.1    Chopra, N.2    Hlaing, T.3    Akin, B.4    Yang, T.5    Ettensohn, K.6
  • 16
    • 1942423621 scopus 로고    scopus 로고
    • The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium
    • Gyorke I., Hester N., Jones L.R., and Gyorke S. The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium. Biophys J 86 (2004) 2121-2128
    • (2004) Biophys J , vol.86 , pp. 2121-2128
    • Gyorke, I.1    Hester, N.2    Jones, L.R.3    Gyorke, S.4
  • 17
    • 0035205336 scopus 로고    scopus 로고
    • A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel
    • Lahat H., Pras E., Olender T., Avidan N., Ben-Asher E., Man O., et al. A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel. Am J Hum Genet 69 (2001) 1378-1384
    • (2001) Am J Hum Genet , vol.69 , pp. 1378-1384
    • Lahat, H.1    Pras, E.2    Olender, T.3    Avidan, N.4    Ben-Asher, E.5    Man, O.6
  • 18
    • 0037131020 scopus 로고    scopus 로고
    • Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia
    • Postma A.V., Denjoy I., Hoorntje T.M., Lupoglazoff J.M., Da C.A., Sebillon P., et al. Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia. Circ Res 91 (2002) e21-e26
    • (2002) Circ Res , vol.91
    • Postma, A.V.1    Denjoy, I.2    Hoorntje, T.M.3    Lupoglazoff, J.M.4    Da, C.A.5    Sebillon, P.6
  • 19
    • 33748512585 scopus 로고    scopus 로고
    • Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia
    • di Barletta M.R., Viatchenko-Karpinski S., Nori A., Memmi M., Terentyev D., Turcato F., et al. Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia. Circulation 114 (2006) 1012-1019
    • (2006) Circulation , vol.114 , pp. 1012-1019
    • di Barletta, M.R.1    Viatchenko-Karpinski, S.2    Nori, A.3    Memmi, M.4    Terentyev, D.5    Turcato, F.6
  • 20
    • 34447133403 scopus 로고    scopus 로고
    • Increased calreticulin and ryanodine receptors by calsequestrin-2 (CASQ2) mutations cause catecholaminergic polymorphic ventricular tachycardia
    • Song L., Alcalai R., Arad M., Cordula M.W., Toka O., Conner D.A., et al. Increased calreticulin and ryanodine receptors by calsequestrin-2 (CASQ2) mutations cause catecholaminergic polymorphic ventricular tachycardia. J Clin Invest 117 (2007) 1814-1823
    • (2007) J Clin Invest , vol.117 , pp. 1814-1823
    • Song, L.1    Alcalai, R.2    Arad, M.3    Cordula, M.W.4    Toka, O.5    Conner, D.A.6
  • 21
    • 36048938672 scopus 로고    scopus 로고
    • Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia
    • Cerrone M., Noujaim S.F., Tolkacheva E.G., Talkachou A., O'Connell R., Berenfeld O., et al. Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia. Circ Res 101 (2007) 1039-1048
    • (2007) Circ Res , vol.101 , pp. 1039-1048
    • Cerrone, M.1    Noujaim, S.F.2    Tolkacheva, E.G.3    Talkachou, A.4    O'Connell, R.5    Berenfeld, O.6
  • 22
    • 53549118870 scopus 로고    scopus 로고
    • Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model
    • Rizzi N., Liu N., Napolitano C., Nori A., Turcato F., Colombi B., et al. Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model. Circ Res 103 (2008) 298-306
    • (2008) Circ Res , vol.103 , pp. 298-306
    • Rizzi, N.1    Liu, N.2    Napolitano, C.3    Nori, A.4    Turcato, F.5    Colombi, B.6
  • 23
    • 0030859331 scopus 로고    scopus 로고
    • The effect of tetracaine on spontaneous Ca2+ release and sarcoplasmic reticulum calcium content in rat ventricular myocytes
    • Overend C.L., Eisner D.A., and O'Neill S.C. The effect of tetracaine on spontaneous Ca2+ release and sarcoplasmic reticulum calcium content in rat ventricular myocytes. J Physiol 502 (1997) 471-479
    • (1997) J Physiol , vol.502 , pp. 471-479
    • Overend, C.L.1    Eisner, D.A.2    O'Neill, S.C.3
  • 24
    • 0033757853 scopus 로고    scopus 로고
    • The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes
    • Trafford A.W., Sibbring G.C., Diaz M.E., and Eisner D.A. The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes. Cell Calcium 28 (2000) 269-276
    • (2000) Cell Calcium , vol.28 , pp. 269-276
    • Trafford, A.W.1    Sibbring, G.C.2    Diaz, M.E.3    Eisner, D.A.4
  • 25
    • 33744973372 scopus 로고    scopus 로고
    • Reducing ryanodine receptor open probability as a means to abolish spontaneous Ca2+ release and increase Ca2+ transient amplitude in adult ventricular myocytes
    • Venetucci L.A., Trafford A.W., Diaz M.E., O'Neill S.C., and Eisner D.A. Reducing ryanodine receptor open probability as a means to abolish spontaneous Ca2+ release and increase Ca2+ transient amplitude in adult ventricular myocytes. Circ Res 98 (2006) 1299-1305
    • (2006) Circ Res , vol.98 , pp. 1299-1305
    • Venetucci, L.A.1    Trafford, A.W.2    Diaz, M.E.3    O'Neill, S.C.4    Eisner, D.A.5
  • 26
    • 0037566339 scopus 로고    scopus 로고
    • An anionic ryanoid, 10-O-succinoylryanodol, provides insights into the mechanisms governing the interaction of ryanoids and the subsequent altered function of ryanodine-receptor channels
    • Tanna B., Welch W., Ruest L., Sutko J.L., and Williams A.J. An anionic ryanoid, 10-O-succinoylryanodol, provides insights into the mechanisms governing the interaction of ryanoids and the subsequent altered function of ryanodine-receptor channels. J Gen Physiol 121 (2003) 551-561
    • (2003) J Gen Physiol , vol.121 , pp. 551-561
    • Tanna, B.1    Welch, W.2    Ruest, L.3    Sutko, J.L.4    Williams, A.J.5
  • 27
    • 0037336233 scopus 로고    scopus 로고
    • Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues
    • Liu H., Atkins J., and Kass R.S. Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues. J Gen Physiol 121 (2003) 199-214
    • (2003) J Gen Physiol , vol.121 , pp. 199-214
    • Liu, H.1    Atkins, J.2    Kass, R.S.3
  • 28
    • 33947157690 scopus 로고    scopus 로고
    • Novel targets for treating heart and muscle disease: stabilizing ryanodine receptors and preventing intracellular calcium leak
    • Lehnart S.E. Novel targets for treating heart and muscle disease: stabilizing ryanodine receptors and preventing intracellular calcium leak. Curr Opin Pharmacol 7 (2007) 225-232
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 225-232
    • Lehnart, S.E.1
  • 29
    • 0032925839 scopus 로고    scopus 로고
    • Effects of a novel cardioprotective drug, JTV-519, on membrane currents of guinea pig ventricular myocytes
    • Kimura J., Kawahara M., Sakai E., Yatabe J., and Nakanishi H. Effects of a novel cardioprotective drug, JTV-519, on membrane currents of guinea pig ventricular myocytes. Jpn J Pharmacol 79 (1999) 275-281
    • (1999) Jpn J Pharmacol , vol.79 , pp. 275-281
    • Kimura, J.1    Kawahara, M.2    Sakai, E.3    Yatabe, J.4    Nakanishi, H.5
  • 30
    • 1842482414 scopus 로고    scopus 로고
    • Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2
    • Wehrens X.H., Lehnart S.E., Reiken S.R., Deng S.X., Vest J.A., Cervantes D., et al. Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2. Science 304 (2004) 292-296
    • (2004) Science , vol.304 , pp. 292-296
    • Wehrens, X.H.1    Lehnart, S.E.2    Reiken, S.R.3    Deng, S.X.4    Vest, J.A.5    Cervantes, D.6
  • 31
    • 0026011647 scopus 로고
    • Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial
    • Echt D.S., Liebson P.R., Mitchell L.B., Peters R.W., Obias-Manno D., Barker A.H., et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med 324 (1991) 781-788
    • (1991) N Engl J Med , vol.324 , pp. 781-788
    • Echt, D.S.1    Liebson, P.R.2    Mitchell, L.B.3    Peters, R.W.4    Obias-Manno, D.5    Barker, A.H.6


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