A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell

Hypertension Research

Volumn 32, Issue 2, 2009, Pages 133-139

  Nagata, Daisuke ^a   Kiyosue, Arihiro ^a   Takahashi, Masao ^a   Satonaka, Hiroshi ^a   Tanaka, Kimie ^a   Sata, Masataka ^a   Nagano, Tetsuo ^b   Nagai, Ryozo ^a   Hirata, Yasunobu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CASPASE 3; CASPASE 7; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GREEN FLUORESCENT PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MUTANT AMP ACTIVATED PROTEIN KINASE ALPHA 1; MUTANT PROTEIN; N(G) NITROARGININE METHYL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BCL 2; PROTEIN KINASE B; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PROTEIN CLEAVAGE; VASCULAR ENDOTHELIUM;

ADENOVIRIDAE; AMINOIMIDAZOLE CARBOXAMIDE; ANOXIA; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 7; CELL DEATH; CROSS-LINKING REAGENTS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA PRIMERS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENETIC VECTORS; HUMANS; MUTATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE TYPE III; ONCOGENE PROTEIN V-AKT; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RIBONUCLEOTIDES; TETRAZOLIUM SALTS;

EID: 68249152343     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2008.25     Document Type: Article

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