Image-guided, intravascular hydrodynamic gene delivery to skeletal muscle in pigs

Molecular Therapy

Volumn 18, Issue 1, 2010, Pages 93-100

  Kamimura, Kenya ^a   Zhang, Guisheng ^a   Liu, Dexi ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; LUCIFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BALLOON CATHETER; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; FLOW RATE; GENE EXPRESSION; HYDRODYNAMICS BASED TRANSFECTION; IMAGING SYSTEM; IMMUNOHISTOCHEMISTRY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIMB SWELLING; NONHUMAN; PRESSURE; SKELETAL MUSCLE; SWINE;

ANIMALS; GENE THERAPY; HINDLIMB; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; LUCIFERASES; MUSCLE, SKELETAL; PHLEBOGRAPHY; PLASMIDS; SWINE;

SUIDAE;

EID: 74149089250     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.206     Document Type: Article

References (26)

1. Liu, F, Song, Y and Liu, D (1999). Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 6: 1258-1266.
2. Zhang, G, Budker, V and Wolff, JA (1999). High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. Hum Gene Ther 10: 1735-1737.
3. Suda, T and Liu, D (2007). Hydrodynamic gene delivery: its principles and applications. Mol Ther 15: 2063-2069.
4. Herweijer, H and Wolff, JA (2007). Gene therapy progress and prospects: hydrodynamic gene delivery. Gene Ther 14: 99-107. (Pubitemid 46043816)
5. Kamimura, K, Suda, T, Xu, W, Zhang, G and Liu, D (2009). Image-guided, lobe-specifc hydrodynamic gene delivery to swine liver. Mol Ther 17: 491-499.
6. Eastman, SJ, Baskin, KM, Hodges, BL, Chu, Q, Gates, A, Dreusicke, R et al. (2002). Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA. Hum Gene Ther 13: 2065-2077.
7. Yoshino, H, Hashizume, K and Kobayashi, E (2006). Naked plasmid DNA transfer to the porcine liver using rapid injection with large volume. Gene Ther 13: 1696-1702.
8. Aliño, SF, Herrero, MJ, Noguera, I, Dasí, F and Sánchez, M (2007). Pig liver gene therapy by noninvasive interventionist catheterism. Gene Ther 14: 334-343.
9. Fabre, JW, Grehan, A, Whitehorne, M, Sawyer, GJ, Dong, X, Salehi, S et al. (2008). Hydrodynamic gene delivery to the pig liver via an isolated segment of the inferior vena cava. Gene Ther 15: 452-462.
10. Khorsandi, SE, Bachellier, P, Weber, JC, Greget, M, Jaeck, D, Zacharoulis, D et al. (2008). Minimally invasive and selective hydrodynamic gene therapy of liver segments in the pig and human. Cancer Gene Ther 15: 225-230.
11. Budker, V, Zhang, G, Danko, I, Williams, P and Wolff, J (1998). The effcient expression of intravascularly delivered DNA in rat muscle. Gene Ther 5: 272-276.
12. Zhang, G, Budker, V, Williams, P, Subbotin, V and Wolff, JA (2001). Effcient expression of naked DNA delivered intraarterially to limb muscles of nonhuman primates. Hum Gene Ther 12: 427-438.
13. Liang, KW, Nishikawa, M, Liu, F, Sun, B, Ye, Q and Huang, L (2004). Restoration of dystrophin expression in mdx mice by intravascular injection of naked DNA containing full-length dystrophin cDNA. Gene Ther 11: 901-908.
14. Zhang, G, Ludtke, JJ, Thioudellet, C, Kleinpeter, P, Antoniou, M, Herweijer, H et al. (2004). Intraarterial delivery of naked plasmid DNA expressing full-length mouse dystrophin in the mdx mouse model of duchenne muscular dystrophy. Hum Gene Ther 15: 770-782.
15. Toumi, H, Hegge, J, Subbotin, V, Noble, M, Herweijer, H, Best, TM et al. (2006). Rapid intravascular injection into limb skeletal muscle: a damage assessment study. Mol Ther 13: 229-236.
16. Danialou, G, Comtois, AS, Matecki, S, Nalbantoglu, J, Karpati, G, Gilbert, R et al. (2005). Optimization of regional intraarterial naked DNA-mediated transgene delivery to skeletal muscles in a large animal model. Mol Ther 11: 257-266.
17. Hagstrom, JE, Hegge, J, Zhang, G, Noble, M, Budker, V, Lewis, DL et al. (2004). A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs. Mol Ther 10: 386-398.
18. Suda, T, Suda, K and Liu, D (2008). Computer-assisted hydrodynamic gene delivery. Mol Ther 16: 1098-1104.
19. Hawkins, IF (1982). Carbon dioxide digital subtraction arteriography. AJR Am J Roentgenol 139: 19-24.
20. 2) digital subtraction angiography: 26-year experience at the University of Florida. Eur Radiol 8: 391-402.
21. Hodges, BL, Taylor, KM, Joseph, MF, Bourgeois, SA and Scheule, RK (2004). Long-term transgene expression from plasmid DNA gene therapy vectors is negatively affected by CpG dinucleotides. Mol Ther 10: 269-278.
22. Yew, NS, Zhao, H, Przybylska, M, Wu, IH, Tousignant, JD, Scheule, RK et al. (2002). CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo. Mol Ther 5: 731-738.
23. Xu, ZL, Mizuguchi, H, Ishii-Watabe, A, Uchida, E, Mayumi, T and Hayakawa, T (2001). Optimization of transcriptional regulatory elements for constructing plasmid vectors. Gene 272: 149-156.
24. Notley, C, Killoran, A, Cameron, C, Wynd, K, Hough, C and Lillicrap, D (2002). The canine factor VIII 3′-untranslated region and a concatemeric hepatocyte nuclear factor 1 regulatory element enhance factor VIII transgene expression in vivo. Hum Gene Ther 13: 1583-1593.
25. Miao, CH, Ye, X and Thompson, AR (2003). High-level factor VIII gene expression in vivo achieved by nonviral liver-specifc gene therapy vectors. Hum Gene Ther 14: 1297-1305.
26. Wolff, LJ, Wolff, JA and Sebestyén, MG (2009). Effect of tissue-specifc promoters and microRNA recognition elements on stability of transgene expression after hydrodynamic naked plasmid DNA delivery. Hum Gene Ther 20: 374-388.