Hepatitis B virus X protein induces hypermethylation of p16INK4A promoter via DNA methyltransferases in the early stage of HBV-associated hepatocarcinogenesis

Journal of Viral Hepatitis

Volumn 17, Issue 2, 2010, Pages 98-107

  Zhu, Y Z ^a   Zhu, R ^a   Fan, J ^a   Pan, Q ^a   Li, H ^a   Chen, Q ^a   Zhu, H G ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

DNA methyltransferase; Hepatitis B virus; Hepatocellular carcinoma; Methylation; X protein

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; HEPATITIS B VIRUS X PROTEIN; METHYL CPG BINDING PROTEIN 2;

ADULT; AGED; ARTICLE; CANCER STAGING; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; FEMALE; GENOTYPE; HEPATITIS B VIRUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PATHOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; DNA-CYTOSINE METHYLASES; FEMALE; HEPATITIS B; HUMANS; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; TRANS-ACTIVATORS;

EID: 74049130932     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2009.01156.x     Document Type: Article

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