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Volumn 68, Issue 2, 2010, Pages 300-308

The Effect of NELL1 and Bone Morphogenetic Protein-2 on Calvarial Bone Regeneration

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; NEL LIKE MOLECULE 1 PROTEIN; POLYGLACTIN; PROTEIN; TISSUE SCAFFOLD; UNCLASSIFIED DRUG;

EID: 73949149208     PISSN: 02782391     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joms.2009.03.066     Document Type: Article
Times cited : (47)

References (66)
  • 3
    • 0034067020 scopus 로고    scopus 로고
    • Craniofacial disorders caused by mutations in homeobox genes MSX1 and MSX2
    • Cohen Jr. M.M. Craniofacial disorders caused by mutations in homeobox genes MSX1 and MSX2. J Craniofac Genet Dev Biol 20 (2000) 19
    • (2000) J Craniofac Genet Dev Biol , vol.20 , pp. 19
    • Cohen Jr., M.M.1
  • 4
    • 0027369180 scopus 로고
    • Suitability of the iliac crest as a site for harvest of autogenous bone grafts
    • Canady J.W., Zeitler D.P., Thompson S.A., et al. Suitability of the iliac crest as a site for harvest of autogenous bone grafts. Cleft Palate Craniofac J 30 (1993) 579
    • (1993) Cleft Palate Craniofac J , vol.30 , pp. 579
    • Canady, J.W.1    Zeitler, D.P.2    Thompson, S.A.3
  • 5
    • 33644805061 scopus 로고    scopus 로고
    • Biological approaches to bone regeneration by gene therapy
    • Franceschi R.T. Biological approaches to bone regeneration by gene therapy. J Dent Res 84 (2005) 1093
    • (2005) J Dent Res , vol.84 , pp. 1093
    • Franceschi, R.T.1
  • 7
    • 0027396823 scopus 로고
    • The coronal approach. Anatomic and technical considerations and morbidity
    • Frodel J.L., and Marentette L.J. The coronal approach. Anatomic and technical considerations and morbidity. Arch Otolaryngol Head Neck Surg 119 (1993) 201
    • (1993) Arch Otolaryngol Head Neck Surg , vol.119 , pp. 201
    • Frodel, J.L.1    Marentette, L.J.2
  • 8
    • 0026077828 scopus 로고
    • Observations on massive retrieved human allografts
    • Enneking W.F., and Mindell E.R. Observations on massive retrieved human allografts. J Bone Joint Surg Am 73 (1991) 1123
    • (1991) J Bone Joint Surg Am , vol.73 , pp. 1123
    • Enneking, W.F.1    Mindell, E.R.2
  • 9
    • 0020640796 scopus 로고
    • Immune responses to osteochondral allografts. Current knowledge and future directions
    • Friedlaender G.E. Immune responses to osteochondral allografts. Current knowledge and future directions. Clin Orthop Relat Res (1983) 58
    • (1983) Clin Orthop Relat Res , pp. 58
    • Friedlaender, G.E.1
  • 10
    • 40749145767 scopus 로고    scopus 로고
    • Autogenous, allogenetic and xenogenetic grafts for maxillary sinus elevation: Literature review, current status and prospects
    • Garofalo G.S. Autogenous, allogenetic and xenogenetic grafts for maxillary sinus elevation: Literature review, current status and prospects. Minerva Stomatol 56 (2007) 373
    • (2007) Minerva Stomatol , vol.56 , pp. 373
    • Garofalo, G.S.1
  • 11
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • Urist M.R. Bone: Formation by autoinduction. Science 150 (1965) 893
    • (1965) Science , vol.150 , pp. 893
    • Urist, M.R.1
  • 12
    • 33748807766 scopus 로고    scopus 로고
    • Nell-1-induced bone regeneration in calvarial defects
    • Aghaloo T., Cowan C.M., Chou Y.F., et al. Nell-1-induced bone regeneration in calvarial defects. Am J Pathol 169 (2006) 903
    • (2006) Am J Pathol , vol.169 , pp. 903
    • Aghaloo, T.1    Cowan, C.M.2    Chou, Y.F.3
  • 13
    • 34547197434 scopus 로고    scopus 로고
    • Enhanced bone regeneration with BMP-2 loaded functional nanoparticle-hydrogel complex
    • Chung Y.I., Ahn K.M., Jeon S.H., et al. Enhanced bone regeneration with BMP-2 loaded functional nanoparticle-hydrogel complex. J Control Release 121 (2007) 91
    • (2007) J Control Release , vol.121 , pp. 91
    • Chung, Y.I.1    Ahn, K.M.2    Jeon, S.H.3
  • 14
    • 34147201090 scopus 로고    scopus 로고
    • MicroCT evaluation of three-dimensional mineralization in response to BMP-2 doses in vitro and in critical sized rat calvarial defects
    • Cowan C.M., Aghaloo T., Chou Y.F., et al. MicroCT evaluation of three-dimensional mineralization in response to BMP-2 doses in vitro and in critical sized rat calvarial defects. Tissue Eng 13 (2007) 501
    • (2007) Tissue Eng , vol.13 , pp. 501
    • Cowan, C.M.1    Aghaloo, T.2    Chou, Y.F.3
  • 15
    • 5444267553 scopus 로고    scopus 로고
    • New scaffold for recombinant human bone morphogenetic protein-2
    • Kamakura S., Nakajo S., Suzuki O., et al. New scaffold for recombinant human bone morphogenetic protein-2. J Biomed Mater Res A 71 (2004) 299
    • (2004) J Biomed Mater Res A , vol.71 , pp. 299
    • Kamakura, S.1    Nakajo, S.2    Suzuki, O.3
  • 16
    • 0001586280 scopus 로고    scopus 로고
    • Application of bone morphogenetic proteins in the treatment of clinical oral and maxillofacial osseous defects
    • Boyne P.J. Application of bone morphogenetic proteins in the treatment of clinical oral and maxillofacial osseous defects. J Bone Joint Surg Am 83 suppl 1 (2001) S146
    • (2001) J Bone Joint Surg Am , vol.83 , Issue.SUPPL. 1
    • Boyne, P.J.1
  • 17
    • 38049013709 scopus 로고    scopus 로고
    • Reduced morbidity and improved healing with bone morphogenic protein-2 in older patients with alveolar cleft defects
    • Dickinson B.P., Ashley R.K., Wasson K.L., et al. Reduced morbidity and improved healing with bone morphogenic protein-2 in older patients with alveolar cleft defects. Plast Reconstr Surg 121 (2008) 209
    • (2008) Plast Reconstr Surg , vol.121 , pp. 209
    • Dickinson, B.P.1    Ashley, R.K.2    Wasson, K.L.3
  • 18
    • 40749112395 scopus 로고    scopus 로고
    • Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2)
    • Herford A.S., and Boyne P.J. Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2). J Oral Maxillofac Surg 66 (2008) 616
    • (2008) J Oral Maxillofac Surg , vol.66 , pp. 616
    • Herford, A.S.1    Boyne, P.J.2
  • 19
    • 0033021062 scopus 로고    scopus 로고
    • Localized, direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration
    • Bonadio J., Smiley E., Patil P., et al. Localized, direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration. Nat Med 5 (1999) 753
    • (1999) Nat Med , vol.5 , pp. 753
    • Bonadio, J.1    Smiley, E.2    Patil, P.3
  • 20
    • 85045483986 scopus 로고    scopus 로고
    • Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: A systematic review
    • Garrison K.R., Donell S., Ryder J., et al. Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: A systematic review. Health Technol Assess 11 (2007) 1
    • (2007) Health Technol Assess , vol.11 , pp. 1
    • Garrison, K.R.1    Donell, S.2    Ryder, J.3
  • 21
    • 18844440475 scopus 로고    scopus 로고
    • The use of cultured bone marrow cells in type I collagen gel and porous hydroxyapatite for posterolateral lumbar spine fusion
    • Minamide A., Yoshida M., Kawakami M., et al. The use of cultured bone marrow cells in type I collagen gel and porous hydroxyapatite for posterolateral lumbar spine fusion. Spine 30 (2005) 1134
    • (2005) Spine , vol.30 , pp. 1134
    • Minamide, A.1    Yoshida, M.2    Kawakami, M.3
  • 22
    • 15844411901 scopus 로고    scopus 로고
    • Ectopic bone formation of human bone morphogenetic protein-2 gene transfected goat bone marrow-derived mesenchymal stem cells in nude mice
    • Tang T.T., Xu X.L., Dai K.R., et al. Ectopic bone formation of human bone morphogenetic protein-2 gene transfected goat bone marrow-derived mesenchymal stem cells in nude mice. Chin J Traumatol 8 (2005) 3
    • (2005) Chin J Traumatol , vol.8 , pp. 3
    • Tang, T.T.1    Xu, X.L.2    Dai, K.R.3
  • 23
    • 0036166542 scopus 로고    scopus 로고
    • Clinical evaluation of recombinant human bone morphogenetic protein-2
    • Valentin-Opran A., Wozney J., Csimma C., et al. Clinical evaluation of recombinant human bone morphogenetic protein-2. Clin Orthop Relat Res (2002) 110
    • (2002) Clin Orthop Relat Res , pp. 110
    • Valentin-Opran, A.1    Wozney, J.2    Csimma, C.3
  • 24
    • 0034277236 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-7 in maxillary sinus floor elevation surgery in 3 patients compared to autogenous bone grafts. A clinical pilot study
    • van den Bergh J.P., ten Bruggenkate C.M., Groeneveld H.H., et al. Recombinant human bone morphogenetic protein-7 in maxillary sinus floor elevation surgery in 3 patients compared to autogenous bone grafts. A clinical pilot study. J Clin Periodontol 27 (2000) 627
    • (2000) J Clin Periodontol , vol.27 , pp. 627
    • van den Bergh, J.P.1    ten Bruggenkate, C.M.2    Groeneveld, H.H.3
  • 25
    • 0036738422 scopus 로고    scopus 로고
    • Craniosynostosis in transgenic mice overexpressing Nell-1
    • Zhang X., Kuroda S., Carpenter D., et al. Craniosynostosis in transgenic mice overexpressing Nell-1. J Clin Invest 110 (2002) 861
    • (2002) J Clin Invest , vol.110 , pp. 861
    • Zhang, X.1    Kuroda, S.2    Carpenter, D.3
  • 26
    • 34548216378 scopus 로고    scopus 로고
    • Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts
    • Cowan C.M., Jiang X., Hsu T., et al. Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts. J Bone Miner Res 22 (2007) 918
    • (2007) J Bone Miner Res , vol.22 , pp. 918
    • Cowan, C.M.1    Jiang, X.2    Hsu, T.3
  • 27
    • 2342586660 scopus 로고    scopus 로고
    • Adipose-derived adult stromal cells heal critical-sized mouse calvarial defects
    • Cowan C., Shi Y., Aalami O., et al. Adipose-derived adult stromal cells heal critical-sized mouse calvarial defects. Nat Biotechnol 22 (2004) 560
    • (2004) Nat Biotechnol , vol.22 , pp. 560
    • Cowan, C.1    Shi, Y.2    Aalami, O.3
  • 28
    • 0033547346 scopus 로고    scopus 로고
    • Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2
    • Kuroda S., Oyasu M., Kawakami M., et al. Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2. Biochem Biophys Res Commun 265 (1999) 79
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 79
    • Kuroda, S.1    Oyasu, M.2    Kawakami, M.3
  • 29
    • 0031818419 scopus 로고    scopus 로고
    • Importance of the critical-size bone defect in testing bone-regenerating materials
    • Bosch C., Melsen B., and Vargervik K. Importance of the critical-size bone defect in testing bone-regenerating materials. J Craniofac Surg 9 (1998) 310
    • (1998) J Craniofac Surg , vol.9 , pp. 310
    • Bosch, C.1    Melsen, B.2    Vargervik, K.3
  • 30
    • 18544379942 scopus 로고    scopus 로고
    • Whole-body skeletal imaging in mice utilizing microPET: Optimization of reproducibility and applications in animal models of bone disease
    • Berger F., Lee Y.P., Loening A.M., et al. Whole-body skeletal imaging in mice utilizing microPET: Optimization of reproducibility and applications in animal models of bone disease. Eur J Nucl Med Mol Imaging 29 (2002) 1225
    • (2002) Eur J Nucl Med Mol Imaging , vol.29 , pp. 1225
    • Berger, F.1    Lee, Y.P.2    Loening, A.M.3
  • 31
    • 0033848937 scopus 로고    scopus 로고
    • Evaluation of changes in trabecular bone architecture and mechanical properties of minipig vertebrae by three-dimensional magnetic resonance microimaging and finite element modeling
    • Borah B., Dufresne T.E., Cockman M.D., et al. Evaluation of changes in trabecular bone architecture and mechanical properties of minipig vertebrae by three-dimensional magnetic resonance microimaging and finite element modeling. J Bone Miner Res 15 (2000) 1786
    • (2000) J Bone Miner Res , vol.15 , pp. 1786
    • Borah, B.1    Dufresne, T.E.2    Cockman, M.D.3
  • 32
    • 34548765981 scopus 로고    scopus 로고
    • A study of the role of Nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation
    • Aghaloo T., Jiang X., Soo C., et al. A study of the role of Nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation. Mol Ther 15 (2007) 1872
    • (2007) Mol Ther , vol.15 , pp. 1872
    • Aghaloo, T.1    Jiang, X.2    Soo, C.3
  • 33
    • 0012940647 scopus 로고    scopus 로고
    • Micro CT and Micro MR imaging of 3D architecture of animal skeleton
    • Jiang Y., Zhao J., White D.L., et al. Micro CT and Micro MR imaging of 3D architecture of animal skeleton. J Musculoskelet Neuronal Interact 1 (2000) 45
    • (2000) J Musculoskelet Neuronal Interact , vol.1 , pp. 45
    • Jiang, Y.1    Zhao, J.2    White, D.L.3
  • 35
    • 18444365600 scopus 로고    scopus 로고
    • Stereological measures of trabecular bone structure: Comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies
    • Thomsen J.S., Laib A., Koller B., et al. Stereological measures of trabecular bone structure: Comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies. J Microsc 218 (2005) 171
    • (2005) J Microsc , vol.218 , pp. 171
    • Thomsen, J.S.1    Laib, A.2    Koller, B.3
  • 36
    • 27744601830 scopus 로고    scopus 로고
    • De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation
    • Boyne P.J., Lilly L.C., Marx R.E., et al. De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation. J Oral Maxillofac Surg 63 (2005) 1693
    • (2005) J Oral Maxillofac Surg , vol.63 , pp. 1693
    • Boyne, P.J.1    Lilly, L.C.2    Marx, R.E.3
  • 37
    • 19044369324 scopus 로고    scopus 로고
    • Randomized study evaluating recombinant human bone morphogenetic protein-2 for extraction socket augmentation
    • Fiorellini J.P., Howell T.H., Cochran D., et al. Randomized study evaluating recombinant human bone morphogenetic protein-2 for extraction socket augmentation. J Periodontol 76 (2005) 605
    • (2005) J Periodontol , vol.76 , pp. 605
    • Fiorellini, J.P.1    Howell, T.H.2    Cochran, D.3
  • 38
    • 33745713060 scopus 로고    scopus 로고
    • Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial
    • Jones A.L., Bucholz R.W., Bosse M.J., et al. Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial. J Bone Joint Surg Am 88 (2006) 1431
    • (2006) J Bone Joint Surg Am , vol.88 , pp. 1431
    • Jones, A.L.1    Bucholz, R.W.2    Bosse, M.J.3
  • 39
    • 0242320424 scopus 로고    scopus 로고
    • Periodontal regeneration in humans using recombinant human platelet-derived growth factor-BB (rhPDGF-BB) and allogenic bone
    • Nevins M., Camelo M., Nevins M.L., et al. Periodontal regeneration in humans using recombinant human platelet-derived growth factor-BB (rhPDGF-BB) and allogenic bone. J Periodontol 74 (2003) 1282
    • (2003) J Periodontol , vol.74 , pp. 1282
    • Nevins, M.1    Camelo, M.2    Nevins, M.L.3
  • 40
    • 41049107103 scopus 로고    scopus 로고
    • Surgical treatment of vertebral osteomyelitis with recombinant human bone morphogenetic protein-2
    • O'Shaughnessy B.A., Kuklo T.R., and Ondra S.L. Surgical treatment of vertebral osteomyelitis with recombinant human bone morphogenetic protein-2. Spine 33 (2008) E132
    • (2008) Spine , vol.33
    • O'Shaughnessy, B.A.1    Kuklo, T.R.2    Ondra, S.L.3
  • 41
    • 0031059353 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts
    • Chen D., Harris M.A., Rossini G., et al. Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts. Calcif Tissue Int 60 (1997) 283
    • (1997) Calcif Tissue Int , vol.60 , pp. 283
    • Chen, D.1    Harris, M.A.2    Rossini, G.3
  • 42
    • 44449142598 scopus 로고    scopus 로고
    • cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo
    • Siddappa R., Martens A., Doorn J., et al. cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo. Proc Natl Acad Sci U S A 105 (2008) 7281
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 7281
    • Siddappa, R.1    Martens, A.2    Doorn, J.3
  • 43
    • 0036899744 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: A prospective, controlled, randomized study of four hundred and fifty patients
    • Govender S., Csimma C., Genant H.K., et al. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: A prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 84 (2002) 2123
    • (2002) J Bone Joint Surg Am , vol.84 , pp. 2123
    • Govender, S.1    Csimma, C.2    Genant, H.K.3
  • 44
    • 0343069792 scopus 로고    scopus 로고
    • Posterolateral intertransverse process spinal arthrodesis with rhBMP-2 in a nonhuman primate: Important lessons learned regarding dose, carrier, and safety
    • Martin Jr. G.J., Boden S.D., Marone M.A., et al. Posterolateral intertransverse process spinal arthrodesis with rhBMP-2 in a nonhuman primate: Important lessons learned regarding dose, carrier, and safety. J Spinal Disord 12 (1999) 179
    • (1999) J Spinal Disord , vol.12 , pp. 179
    • Martin Jr., G.J.1    Boden, S.D.2    Marone, M.A.3
  • 45
    • 0032925143 scopus 로고    scopus 로고
    • Human NELL-1 expressed in unilateral coronal synostosis
    • Ting K., Vastardis H., Mulliken J.B., et al. Human NELL-1 expressed in unilateral coronal synostosis. J Bone Miner Res 14 (1999) 80
    • (1999) J Bone Miner Res , vol.14 , pp. 80
    • Ting, K.1    Vastardis, H.2    Mulliken, J.B.3
  • 46
    • 10744226842 scopus 로고    scopus 로고
    • Overexpression of Nell-1, a craniosynostosis-associated gene, induces apoptosis in osteoblasts during craniofacial development
    • Zhang X., Carpenter D., Bokui N., et al. Overexpression of Nell-1, a craniosynostosis-associated gene, induces apoptosis in osteoblasts during craniofacial development. J Bone Miner Res 18 (2003) 2126
    • (2003) J Bone Miner Res , vol.18 , pp. 2126
    • Zhang, X.1    Carpenter, D.2    Bokui, N.3
  • 47
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R., and Zhang Y.E. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425 (2003) 577
    • (2003) Nature , vol.425 , pp. 577
    • Derynck, R.1    Zhang, Y.E.2
  • 48
    • 0037126380 scopus 로고    scopus 로고
    • Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein
    • Lee K.S., Hong S.H., and Bae S.C. Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein. Oncogene 21 (2002) 7156
    • (2002) Oncogene , vol.21 , pp. 7156
    • Lee, K.S.1    Hong, S.H.2    Bae, S.C.3
  • 49
    • 0036021077 scopus 로고    scopus 로고
    • Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5
    • Nishimura R., Hata K., Harris S.E., et al. Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5. Bone 31 (2002) 303
    • (2002) Bone , vol.31 , pp. 303
    • Nishimura, R.1    Hata, K.2    Harris, S.E.3
  • 50
    • 29344461912 scopus 로고    scopus 로고
    • Nell-1 induced bone formation within the distracted intermaxillary suture
    • Cowan C.M., Cheng S., Ting K., et al. Nell-1 induced bone formation within the distracted intermaxillary suture. Bone 38 (2006) 48
    • (2006) Bone , vol.38 , pp. 48
    • Cowan, C.M.1    Cheng, S.2    Ting, K.3
  • 51
    • 33845937676 scopus 로고    scopus 로고
    • Craniosynostosis-associated gene nell-1 is regulated by runx2
    • Truong T., Zhang X., Pathmanathan D., et al. Craniosynostosis-associated gene nell-1 is regulated by runx2. J Bone Miner Res 22 (2007) 7
    • (2007) J Bone Miner Res , vol.22 , pp. 7
    • Truong, T.1    Zhang, X.2    Pathmanathan, D.3
  • 52
    • 33745163927 scopus 로고    scopus 로고
    • Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development
    • Zhang X., Cowan C.M., Jiang X., et al. Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development. Lab Invest 86 (2006) 633
    • (2006) Lab Invest , vol.86 , pp. 633
    • Zhang, X.1    Cowan, C.M.2    Jiang, X.3
  • 54
    • 37849048694 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalcium phosphate
    • Jung R.E., Weber F.E., Thoma D.S., et al. Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalcium phosphate. Clin Oral Implants Res 19 (2008) 188
    • (2008) Clin Oral Implants Res , vol.19 , pp. 188
    • Jung, R.E.1    Weber, F.E.2    Thoma, D.S.3
  • 55
    • 43749120033 scopus 로고    scopus 로고
    • Retention of in vitro and in vivo BMP-2 bioactivities in sustained delivery vehicles for bone tissue engineering
    • Kempen D.H., Lu L., Hefferan T.E., et al. Retention of in vitro and in vivo BMP-2 bioactivities in sustained delivery vehicles for bone tissue engineering. Biomaterials 29 (2008) 3245
    • (2008) Biomaterials , vol.29 , pp. 3245
    • Kempen, D.H.1    Lu, L.2    Hefferan, T.E.3
  • 56
    • 33847046788 scopus 로고    scopus 로고
    • Skull bone regeneration in nonhuman primates by controlled release of bone morphogenetic protein-2 from a biodegradable hydrogel
    • Takahashi Y., Yamamoto M., Yamada K., et al. Skull bone regeneration in nonhuman primates by controlled release of bone morphogenetic protein-2 from a biodegradable hydrogel. Tissue Eng 13 (2007) 293
    • (2007) Tissue Eng , vol.13 , pp. 293
    • Takahashi, Y.1    Yamamoto, M.2    Yamada, K.3
  • 57
    • 3242804594 scopus 로고    scopus 로고
    • Oxysterols regulate differentiation of mesenchymal stem cells: Pro-bone and anti-fat
    • Kha H.T., Basseri B., Shouhed D., et al. Oxysterols regulate differentiation of mesenchymal stem cells: Pro-bone and anti-fat. J Bone Miner Res 19 (2004) 830
    • (2004) J Bone Miner Res , vol.19 , pp. 830
    • Kha, H.T.1    Basseri, B.2    Shouhed, D.3
  • 58
    • 33144468578 scopus 로고    scopus 로고
    • C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via Smad5 phosphorylation
    • Yeh L.C., Zavala M.C., and Lee J.C. C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via Smad5 phosphorylation. J Cell Biochem 97 (2006) 494
    • (2006) J Cell Biochem , vol.97 , pp. 494
    • Yeh, L.C.1    Zavala, M.C.2    Lee, J.C.3
  • 59
    • 0036154985 scopus 로고    scopus 로고
    • Osteogenic protein-1 and interleukin-6 with its soluble receptor synergistically stimulate rat osteoblastic cell differentiation
    • Yeh L.C., Zavala M.C., and Lee J.C. Osteogenic protein-1 and interleukin-6 with its soluble receptor synergistically stimulate rat osteoblastic cell differentiation. J Cell Physiol 190 (2002) 322
    • (2002) J Cell Physiol , vol.190 , pp. 322
    • Yeh, L.C.1    Zavala, M.C.2    Lee, J.C.3
  • 60
    • 7544238376 scopus 로고    scopus 로고
    • Cartilage-derived morphogenetic proteins enhance the osteogenic protein-1-induced osteoblastic cell differentiation of C2C12 cells
    • Yeh L.C., Tsai A.D., Zavala M.C., et al. Cartilage-derived morphogenetic proteins enhance the osteogenic protein-1-induced osteoblastic cell differentiation of C2C12 cells. J Cell Physiol 201 (2004) 401
    • (2004) J Cell Physiol , vol.201 , pp. 401
    • Yeh, L.C.1    Tsai, A.D.2    Zavala, M.C.3
  • 61
    • 33947508765 scopus 로고    scopus 로고
    • Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation
    • Ghosh-Choudhury N., Mandal C.C., and Choudhury G.G. Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation. J Biol Chem 282 (2007) 4983
    • (2007) J Biol Chem , vol.282 , pp. 4983
    • Ghosh-Choudhury, N.1    Mandal, C.C.2    Choudhury, G.G.3
  • 62
    • 41149125432 scopus 로고    scopus 로고
    • Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway
    • Yamashita M., Otsuka F., Mukai T., et al. Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway. J Endocrinol 196 (2008) 601
    • (2008) J Endocrinol , vol.196 , pp. 601
    • Yamashita, M.1    Otsuka, F.2    Mukai, T.3
  • 63
    • 17444410838 scopus 로고    scopus 로고
    • Simvastatin promotes cell metabolism, proliferation, and osteoblastic differentiation in human periodontal ligament cells
    • Yazawa H., Zimmermann B., Asami Y., et al. Simvastatin promotes cell metabolism, proliferation, and osteoblastic differentiation in human periodontal ligament cells. J Periodontol 76 (2005) 295
    • (2005) J Periodontol , vol.76 , pp. 295
    • Yazawa, H.1    Zimmermann, B.2    Asami, Y.3
  • 64
    • 0036738338 scopus 로고    scopus 로고
    • Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4
    • Peng H., Wright V., Usas A., et al. Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. J Clin Invest 110 (2002) 751
    • (2002) J Clin Invest , vol.110 , pp. 751
    • Peng, H.1    Wright, V.2    Usas, A.3
  • 65
    • 0345688670 scopus 로고    scopus 로고
    • Parathyroid hormone-related peptide interacts with bone morphogenetic protein 2 to increase osteoblastogenesis and decrease adipogenesis in pluripotent C3H10T 1/2 mesenchymal cells
    • Chan G.K., Miao D., Deckelbaum R., et al. Parathyroid hormone-related peptide interacts with bone morphogenetic protein 2 to increase osteoblastogenesis and decrease adipogenesis in pluripotent C3H10T 1/2 mesenchymal cells. Endocrinology 144 (2003) 5511
    • (2003) Endocrinology , vol.144 , pp. 5511
    • Chan, G.K.1    Miao, D.2    Deckelbaum, R.3
  • 66
    • 27444446737 scopus 로고    scopus 로고
    • VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis
    • Peng H., Usas A., Olshanski A., et al. VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. J Bone Miner Res 20 (2005) 2017
    • (2005) J Bone Miner Res , vol.20 , pp. 2017
    • Peng, H.1    Usas, A.2    Olshanski, A.3


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