C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via smad5 phosphorylation

Journal of Cellular Biochemistry

Volumn 97, Issue 3, 2006, Pages 494-500

  Yeh, Lee Chuan C ^a   Zavala, Michelle C ^a   Lee, John C ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Bone morphogenetic protein 7; C natriuretic peptide; Osteoblast differentiation; Osteogenic protein 1; Smads; Synergy

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; BONE MORPHOGENETIC PROTEIN RECEPTOR IB; NATRIURETIC PEPTIDE TYPE C; OSTEOGENIC PROTEIN 1; SMAD5 PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MINERALIZATION; CALVARIA; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; FETUS; GENE EXPRESSION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; ANIMALS; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DRUG SYNERGISM; FETUS; NATRIURETIC PEPTIDE, C-TYPE; OSTEOBLASTS; OSTEOGENESIS; PHOSPHORYLATION; RATS; SKULL; SMAD1 PROTEIN; SMAD5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 33144468578     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20657     Document Type: Article

References (24)

1. Cook SD. 1999. Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites [see comments]. Orthopedics 22:669-671.
2. Hagiwara H, Inoue A, Yamaguchi A, Yokose S, Furuya M, Tanaka S, Hirose S. 1996. cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells. Am J Physiol 270:C1311-1318.
3. Holliday LS, Dean AD, Greenwald JE, Glucks SL. 1995. C-type natriuretic peptide increases bone resorption in 1,25- dihydroxyvitamin D3-stimulated mouse bone marrow cultures. J Biol Chem 270:18983-18989.
4. Inoue A, Hiruma Y, Hirose S, Yamaguchi A, Furuya M, Tanaka S, Hagiwara H. 1996a. Stimulation by C-type natriuretic peptide of the differentiation of clonal osteoblastic MC3T3-E1 cells. Biochem Biophys Res Commun 221:703-707.
5. Inoue A, Otsuka E, Hiruma Y, Hirose S, Furuya M, Tanaka S, Hagiwara H. 1996b. Stimulation by retinoids of the natriuretic peptide system of osteoblastic MC3T3-E1 cells. Biochem Biophys Res Commun 228:182-186.
6. Inoue A, Hayakawa T, Otsuka E, Kamiya A, Suzuki Y, Hirose S, Hagiwara H. 1999. Correlation between induction of expression of biglycan and mineralization by C-type natriuretic peptide in osteoblastic cells. J Biochem (Tokyo) 125:103-108.
7. Inoue A, Kobayashi Y, Ishizuka M, Hirose S, Hagiwara H. 2002. Identification of a novel osteoblastic gene, inducible by C-type natriuretic peptide, whose transcript might function in mineralization as a noncoding RNA. Calcif Tissue Int 70:111-116.
8. Jaubert J, Jaubert F, Martin N, Washburn LL, Lee BK, Eicher EM, Guenet JL. 1999. Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene (Npr3). Proc Natl Acad Sci USA 96:10278-10283.
9. Kingsley DM. 1994. The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8:133-146.
10. Komatsu Y, Nakao K, Suga S, Ogawa Y, Mukoyama M, Arai H, Shirakami G, Hosoda K, Nakagawa O, Hama N. 1991. C-type natriuretic peptide (CNP) in rats and humans. Endocrinology 129:1104-1106.
11. Komatsu Y, Chusho H, Tamura N, Yasoda A, Miyazawa T, Suda M, Miura M, Ogawa Y, Nakao K. 2002. Significance of C-type natriuretic peptide (CNP) in endochondral ossification: Analysis of CNP knockout mice. J Bone Miner Metab 20:331-336.
12. Korchynskyi O, van Bezooijen R, Lowik CWGM, ten Dijke P. 2004. Bone morphogenetic protein receptors and their nuclear effectors in bone formation. In: Vukicevic S, Sampath KT (eds): "Bone morphogenetic proteins: Regerenation of bone and beyond." Basel/Switzerland: Birkhauser Verlag, pp 9-44.
13. Massague J. 2000. How cells read TGF-beta signals. Nat Rev Mol Cell Biol 1:169-178.
14. Miyazawa T, Ogawa Y, Chusho H, Yasoda A, Tamura N, Komatsu Y, Pfeifer A, Hofmann F, Nakao K. 2002. Cyclic GMP-dependent protein kinase II plays a critical role in C-type natriuretic peptide-mediated endochondral ossification. Endocrinology 143:3604-3610.
15. Rosenzweig A, Seidman CE. 1991. Atrial natriuretic factor and related peptide hormones. Annu Rev Biochem 60: 229-255.
16. Sampath TK, Maliakal JC, Hauschka PV, Jones WK, Sasak H, Tucker RF, White KH, Coughlin JE, Tucker MM, Pang RH, Corbett C, Ozkaynak E, Oppermann H, Rueger DC. 1992. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J Biol Chem 267:20352-20362.
17. Suda M, Tanaka K, Fukushima M, Natsui K, Yasoda A, Komatsu Y, Ogawa Y, Itoh H, Nakao K. 1996. C-type natriuretic peptide as an autocrine/paracrine regulator of osteoblast. Evidence for possible presence of bone natriuretic peptide system. Biochem Biophys Res Commun 223:1-6.
18. Suga S, Nakao K, Itoh H, Komatsu Y, Ogawa Y, Kama N, Imura H. 1992. Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system". J Clin Invest 90: 1145-1149.
19. Tamaki K, Souchelnytskyi S, Itoh S, Nakao A, Sampath K, Heldin CH, ten Dijke P. 1998. Intracellular signaling of osteogenic protein-1 through Smad5 activation. J Cell Physiol 177:355-363.
20. ten Dijke P, Fu J, Schaap P, Roelen BA. 2003. Signal transduction of bone morphogenetic proteins in osteoblast differentiation. J Bone Joint Surg Am 85 ( Suppl 3): 34-38.
21. Vollmar AM, Gerbes AL, Nemer M, Schulz R. 1993. Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs. Endocrinology 132:1872-1874.
22. Yasoda A, Ogawa Y, Suda M, Tamura N, Mori K, Sakuma Y, Chusho H, Shiota K, Tanaka K, Nakao K. 1998. Natriuretic peptide regulation of endochondral ossification. Evidence for possible roles of the C-type natriuretic peptide/guanylyl cyclase-B pathway. J Biol Chem 273: 11695-11700.
23. Yeh LC, Adamo ML, Olson MS, Lee JC. 1997. Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation. Endocrinology 138:4181-4190.
24. Yeh LC, Tsai AD, Zavala MC, Lee JC. 2004. Cartilage-derived morphogenetic proteins enhance the osteogenic protein-1-induced osteoblastic cell differentiation of C2C12 cells. J Cell Physiol 201:401-408.