Simvastatin promotes cell metabolism, proliferation, and osteoblastic differentiation in human periodontal ligament cells

Journal of Periodontology

Volumn 76, Issue 2, 2005, Pages 295-302

  Yazawa, Hiroshi ^a,b   Zimmermann, Bernd ^b   Asami, Yoshiko ^b   Bernimoulin, Jean Pierre ^a  

^a University Medical School   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cell differentiation; Cells, periodontal; Osteoblasts; Periodontal ligament; Periodontal regeneration; Simvastatin therapeutic use

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CALCIUM; MEVALONIC ACID; OSTEOCALCIN; OSTEOPONTIN; SIMVASTATIN;

ADOLESCENT; ADULT; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL METABOLISM; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MONOLAYER CULTURE; OSTEOBLAST; PERIODONTAL LIGAMENT;

ADOLESCENT; ADULT; ALKALINE PHOSPHATASE; ANALYSIS OF VARIANCE; BONE MORPHOGENETIC PROTEINS; CALCIUM; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MEVALONIC ACID; OSTEOBLASTS; OSTEOCALCIN; OSTEOPONTIN; PERIODONTAL LIGAMENT; SIALOGLYCOPROTEINS; SIMVASTATIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 17444410838     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2005.76.2.295     Document Type: Article

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